ライフサイエンスコーパス: protein refolding

1 cing G conformational changes that trigger F protein refolding.

2 ative in vitro assay for this step in fusion protein refolding.

3 aster than anticipated from models involving protein refolding.

4 bstrates from one another, leading to native protein refolding.

5 which intercalates target membranes during F protein refolding.

6 nts were blocked in distinct steps in fusion protein refolding.

7 al ion affinity purification and solid-phase protein refolding.

8 brane transport, protein disaggregation, and protein refolding.

9 ent mechanism that allows HdeA to facilitate protein refolding.

10 In vitro studies show that TF promotes protein refolding.

11 at undergoes major structural changes during protein refolding.

12 lling experiments that involve rapid in situ protein refolding.

13 bending and/or the extent of binding-induced protein refolding.

14 st aggregation, especially in the process of protein refolding.

15 r branches of the ER stress response mediate protein refolding.

16 target protein aggregation or enhance target protein refolding.

17 tity with BAG-1 and inhibits Hsp70- mediated protein refolding.

18 tein Ydj1, to partner with Hsp70 in in vitro protein refolding.

19 or kinetic studies of disulfide bond-induced protein refolding.

20 phosphorylation-initiated mechanism of local protein refolding activates yeast glycogen phosphorylase

21 li, results in significant impairment of its protein refolding activity in vitro without affecting in

22 demonstrate that BAG-1 inhibits the in vitro protein refolding activity of Hsp70 by forming stable te

23 es are ubiquitous enzymes that stimulate the protein refolding activity of Hsp70 family chaperones.

24 of JNK suppression, thus indicating that the protein refolding activity of Hsp72 is not critical for

25 tructure less than temperature denaturation, protein refolding after a fast P-jump is not necessarily

26 chains to study how the competition between protein refolding and aggregation affects the optimal co

27 The IRE1-XBP1 pathway directs both protein refolding and degradation in response to ER stre

28 s a necessary early step for paramyxovirus F-protein refolding and presents a novel target for struct

29 the development of automated approaches for protein refolding and purification.

30 oteostasis, including quality control during protein refolding and regulation of protein degradation.

31 Proteins involved in protein refolding and response to oxidative stress appea

32 iation reduced Hsp70 chaperone activities of protein refolding and survival after heat shock.

33 We find little difference in ATPase, protein refolding, and amyloid inhibiting activities of

34 d full-length and truncated TPO in assays of protein refolding, and we examined protein stability in

35 The inhibitory effects of GdnHCl protein refolding are partially suppressed by elevating

36 Using an established protein refolding assay, we demonstrate here that fibron

37 n shown that Hsp70 and Hsp90 act not only in protein refolding but also cooperate with the C terminus

38 While the molecular basis of fusion (F) protein refolding during membrane fusion has been studie

39 virus exit and that sense low pH and mediate protein refolding during virus entry.

40 es are necessary for the rapid, productive S protein refolding events that culminate in membrane fusi

41 lecules, "artificial chaperones," facilitate protein refolding from a chemically denatured state.

42 Here, we report that protein refolding from the acid-denatured state of PYP m

43 Thus, pressure-jump (P-jump)-induced protein refolding, if it could be made fast enough, woul

44 qualitatively akin to that observed with the protein refolding in buffer.

45 We show that for a mixture of proteins refolding in vitro, folding intermediates do no

46 Analysis of intermediate steps in F protein refolding indicated that the mutants were not tr

47 the effect of a cyclodextrin substitution on protein refolding is not possible at present, these resu

48 virtually monomeric unfolded state, however, protein refolding leads to the formation of severely sel

49 timize the phosphocholine motif for membrane protein refolding led to the identification of two new d

50 eraction partners and that context-dependent protein refolding may be widespread in nature.

51 of a quality control system that facilitates protein refolding or degradation during recovery from st

52 attenuate protein translation, and increase protein refolding or degradation.

53 hlighted key conformational changes in the F-protein refolding pathway, but a detailed understanding

54 ion of recombinant proteins often requires a protein-refolding process for recovery of high yields.

55 ured purified protein and in the analysis of protein refolding products promise to remove bottlenecks

56 fic and interconnected aspects of the fusion protein refolding reaction.

57 However, protein refolding reactions using ADP-fluoroaluminate co

58 ion of partially folded intermediates during protein refolding results in the termination of further

59 We recently reported a new approach to protein refolding that utilizes a pair of low molecular

60 During protein refolding there is kinetic partitioning between

61 couple the energy released from irreversible protein refolding to the work of membrane fusion.

62 r, and (iv) characterize the early stages of protein refolding when chemically denatured proteins are