ライフサイエンスコーパス: proteinase inhibitor

1 ively sensitive NE inhibitors (e.g., alpha-1-proteinase inhibitor).

2 mal melting temperature but is inactive as a proteinase inhibitor.

3 ments with the homologous segments of alpha1-proteinase inhibitor.

4 r 30 min or by treating them with a cysteine proteinase inhibitor.

5 inase-1, -2, and -4, and secretory leukocyte proteinase inhibitor.

6 creted myxoma virus anti-inflammatory serine proteinase inhibitor.

7 selective inhibition of secretory leukocyte proteinase inhibitor.

8 ld convert SCCA2 into a more potent cysteine proteinase inhibitor.

9 bound to immobilized TSP-1 remains an active proteinase inhibitor.

10 and bikunin, a broad-specificity Kunitz-type proteinase inhibitor.

11 ived factor (PEDF), a multifunctional serine proteinase inhibitor.

12 ning into lipid rafts or cleavage of alpha-1-proteinase inhibitor.

13 e genes encoded functional, dual cross-class proteinase inhibitors.

14 inhibited with synthetic and natural serine proteinase inhibitors.

15 to substrate specificity and sensitivity to proteinase inhibitors.

16 tivity and native wall extension activity to proteinase inhibitors.

17 or advancing the therapeutic use of clinical proteinase inhibitors.

18 when medium was supplemented with one of the proteinase inhibitors.

19 nted with any one or all of the above serine proteinase inhibitors.

20 R3 is resistant to inhibition by physiologic proteinase inhibitors.

21 ible peptide bonds in the design of aspartic proteinase inhibitors.

22 ted Abeta degradation is inhibited by serine proteinase inhibitors.

23 pecies and are mostly thiol ester containing proteinase inhibitors.

24 virus encodes the Egf family of small serine proteinase inhibitors.

25 n growth rate, morphology and sensitivity to proteinase inhibitors.

26 irect defense metabolites, including trypsin proteinase inhibitors, 17-hydroxygeranyllinallool diterp

27 ion of late responding defense genes such as proteinase inhibitor 2 (Pin2).

28 of the substrate-like Schistocerca gregaria proteinase inhibitor 2 (SGPI-2) to select reversible hig

29 ere inhibited by treatment with the cysteine proteinase inhibitor (2S,3S)-transepoxysuccinyl-L-leucyl

30 r 9 (PI-9), or the murine orthologue, serine proteinase inhibitor 6 (SPI-6), confers resistance to CT

31 -9/serpinB9) and the murine ortholog, serine proteinase inhibitor 6 (SPI-6/serpinb9) are members of a

32 oding a related serine proteinase inhibitor, proteinase inhibitor 8, were unaffected by culture of Hu

33 levels of the granzyme B inhibitor, SerpinB9/proteinase inhibitor 9 (PI-9) and progressively block ce

34 posite estrogen-responsive unit (ERU) in the proteinase inhibitor 9 (PI-9) gene.

35 Proteinase inhibitor 9 (PI-9) inhibits caspase-1 (interl

36 pression of the granzyme B inhibitors, human proteinase inhibitor 9 (PI-9), or the murine orthologue,

37 Human proteinase inhibitor 9 (PI-9/serpinB9) and the murine or

38 ibits E(2)-ERalpha-mediated induction of the proteinase inhibitor 9 gene, which is activated by ERalp

39 ssibility that this orphan granzyme bypasses proteinase inhibitor 9 inhibition of granzyme B.

40 otrypsin, alpha(1)-proteinase inhibitor, and proteinase inhibitor 9 was characterized by using a cand

41 Proteinase inhibitor 9 was effectively hydrolyzed and in

42 We identified proteinase inhibitor 9, or PI-9, as being rapidly and st

43 roteinase inhibitor (SLPI) is a major serine proteinase inhibitor, a potent antibiotic, and thus a po

44 The efficacy of alpha1 proteinase inhibitor (A1PI) augmentation treatment for a

45 Purified alpha1 proteinase inhibitor (A1PI) slowed emphysema progression

46 The Z variant of human alpha-1 proteinase inhibitor (A1PiZ) is a substrate for endoplas

47 monic acid-dependent pathway is utilized for proteinase inhibitor accumulation in response to salt st

48 We report here that the induction of proteinase inhibitor accumulation in tomato leaves by pl

49 is incubated in chambers with tomato plants, proteinase inhibitor accumulation is induced in the toma

50 The proteinase inhibitor activity and expression of JA-relat

51 Here, we report the proteinase inhibitor activity of NaStEP.

52 The human plasma proteinase inhibitor alpha(2)-macroglobulin (alpha(2)M)

53 ands including the activated form of the pan-proteinase inhibitor alpha(2)-macroglobulin (alpha(2)M*)

54 elevated, and those of the inhibitors alpha1-proteinase inhibitor (alpha 1-PI) and alpha 2-macroglobu

55 NSP4 was inhibited by alpha(1)-proteinase inhibitor (alpha(1)-antitrypsin), C1 inhibito

56 alpha(1)-Proteinase inhibitor (alpha(1)-PI) is a member of the se

57 covalent complex between the serpin alpha(1)-proteinase inhibitor (alpha(1)PI) and anhydroelastase co

58 tional distributions of trypsin and alpha(1)-proteinase inhibitor (alpha(1)PI) covalent complexes.

59 (15)N-alanine specifically-labeled alpha(1)-proteinase inhibitor (alpha(1)PI) Pittsburgh (serpin) an

60 plasma components were found to be alpha(1)-proteinase inhibitor, alpha(1)-antichymotrypsin, and alp

61 mpB had proteolytic activity against alpha-1 proteinase inhibitor, alpha(2)-macrogobulin, type IV col

62 monstrated that administration of the serine proteinase inhibitor alpha1-antitrypsin (AAT) prevents t

63 We show here that the plasma proteinase inhibitors alpha1-proteinase inhibitor, alpha

64 mpaired catalysis and inactivation by alpha1-proteinase inhibitor (alpha1-antitrypsin).

65 itors I and II were identified to be alpha-1-proteinase inhibitor (alpha1-PI) based on LC-MS/MS.

66 s homozygous for the Z mutant form of alpha1-proteinase inhibitor (alpha1-PI) have an increased risk

67 regulates NE activity by inactivating alpha1-proteinase inhibitor (alpha1-PI).

68 that the plasma proteinase inhibitors alpha1-proteinase inhibitor, alpha1-antichymotrypsin, and alpha

69 y purified, then analyzed for the endogenous proteinase inhibitor, alpha1-PI, and its breakdown produ

70 dependence for the natural HLE ligand alpha1 proteinase inhibitor (alpha1antitrypsin, alpha1PI).

71 In contrast, alpha1-proteinase inhibitor (alpha1PI) Pittsburgh (P1 Met --> A

72 ons in a P1 Arg variant of the serpin alpha1-proteinase inhibitor (alpha1PI) that does not require he

73 a covalent serpin-proteinase complex, alpha1-proteinase inhibitor (alpha1PI) with porcine pancreatic

74 Previous studies of the plasma proteinase inhibitor alpha2-macroglobulin (alpha2M) demo

75 binding of receptor-recognized forms of the proteinase inhibitor alpha2-macroglobulin (alpha2M*) to

76 Binding of activated forms of the proteinase inhibitor alpha2-macroglobulin (alpha2M*) to

77 of PAK-2 in 1-LN prostate cancer cells by a proteinase inhibitor, alpha2-macroglobulin.

78 superoxide dismutase, inositol, and alpha-1 proteinase inhibitor also are warranted on the basis of

79 Leupeptin and a mixture of proteinase inhibitors also attenuated GRgpA-induced resp

80 It would appear that HIV proteinase inhibitors also have a direct effect on one o

81 Our work identifies STC2 as a novel proteinase inhibitor and a previously unrecognized extra

82 The chemically inactivated alpha(1)-proteinase inhibitor and alpha(2)-macroglobulin lose the

83 with their physiological inhibitors, alpha1-proteinase inhibitor and alpha1-antichymotrypsin.

84 pression of a biosafe, anti-feedant cysteine proteinase inhibitor and an anti-root invasion, non-leth

85 Similar experiments with alpha(1)-proteinase inhibitor and antithrombin, two inhibitory se

86 (2)-Macroglobulin (alpha(2)M) functions as a proteinase inhibitor and as a carrier of diverse growth

87 Both Pittsburgh mutant of alpha(1)-proteinase inhibitor and dec-Arg-Val-Lys-Arg-chloromethy

88 KTI gene encodes a putative 15-domain serine proteinase inhibitor and has been linked to the inherite

89 7)-Met(358) in the reactive loop of alpha(1)-proteinase inhibitor and His(140)-Val(141) in insulin-li

90 Wild-type mice given NE inhibitors (alpha1-proteinase inhibitor and Me-O-Suc-Ala-Ala-Pro-Val-CH(2)C

91 demonstrate that S49P neuroserpin is a poor proteinase inhibitor and readily forms loop-sheet polyme

92 These include proteinase inhibitors and biosynthetic enzymes for produ

93 ng the exposure of the insects to sugar beet proteinase inhibitors and build up of non-sensitive midg

94 s show that Ddi1 proteins are targets of HIV proteinase inhibitors and indicates the Leishmania Ddi1

95 g KL-transfected COS-7 cells with a panel of proteinase inhibitors and measuring cleavage products by

96 These genes, including those of four proteinase inhibitors and polyphenol oxidase, are expres

97 that salt stress causes the accumulation of proteinase inhibitors and the activation of other wound-

98 spermiogenesis (metalloproteinase and serine proteinase inhibitors), and steroidogenesis (CYP21A2 and

99 SERPINA3K is a serine proteinase inhibitor, and its levels were decreased in r

100 cofactor's binding to and activation of the proteinase inhibitor, and its salt dependence indicates

101 serpins alpha(1)-antichymotrypsin, alpha(1)-proteinase inhibitor, and proteinase inhibitor 9 was cha

102 bioactive molecules such as growth factors, proteinase inhibitors, and cytokines.

103 ed substrate zymography, reverse zymography, proteinase inhibitors, and partial sequencing to investi

104 ydrolases, ABC transporters, protein toxins, proteinase inhibitors, and, in particular, a superfamily

105 and the functional activation of, the serine proteinase inhibitor antithrombin.

106 tidase superfamily, and an 11.4-kDa alkaline proteinase inhibitor (APRin).

107 The serpins (SERine Proteinase INhibitors) are a family of proteins with imp

108 n that retinal levels of SERPINA3K, a serine proteinase inhibitor, are decreased in an animal model w

109 ars, glycoalkaloids, and jasmonate-regulated proteinase inhibitors, are produced in od-2 leaves.

110 and in complexes of increasing size with the proteinase inhibitors BPTI (total molecular mass 31 kDa)

111 , indicating that these proteins function as proteinase inhibitors but not as adhesion molecules.

112 eaves types I and II collagens, and alpha(1)-proteinase inhibitor, but is substantially resistant to

113 equired for the salt-induced accumulation of proteinase inhibitors, but was necessary to achieve maxi

114 titors, T. forsythia possesses a serpin-type proteinase inhibitor called miropin.

115 However, based on the use of proteinase inhibitors, cell death changes from being pri

116 e defects of a strand 3C antithrombin-alpha1-proteinase inhibitor chimera in reactions of the heparin

117 osites, we prepared six antithrombin-alpha 1-proteinase inhibitor chimeras in which antithrombin resi

118 Serine proteinase inhibitor, clade E, member 2 (SERPINE2), is a

119 samples was impaired using a broad-spectrum proteinase inhibitor cocktail, but not the pan-specific

120 NAH), cathepsin D (CD), and elastase-alpha-1-proteinase inhibitor complex (alpha-1-EPI) before and 6

121 X-ray crystallography of the proteinase-inhibitor complex reveals that five N-termina

122 m of numerous ligands including proteinases, proteinase inhibitor complexes, and lipoproteins.

123 rs concurrently with the formation of stable proteinase-inhibitor complexes.

124 The cystatin superfamily of cysteine proteinase inhibitors consists of three major families.

125 Renaturation of the small proteinase inhibitor cystatin under oxidizing versus red

126 in turn, reduced the production of cysteine proteinase inhibitors (CystPIs), which are specific dete

127 In addition, both proteinase inhibitors demonstrated significant reduction

128 Labeling of these polypeptides with a serine proteinase inhibitor, diisopropyl fluorophosphate, indic

129 isoforms of AbetaPP that contain the Kunitz proteinase inhibitor domain are analogous to the previou

130 a soluble isoform of APP containing a Kunitz proteinase inhibitor domain but not soluble APP lacking

131 domain but not soluble APP lacking a Kunitz proteinase inhibitor domain.

132 ytosis of APP isoforms containing the Kunitz proteinase inhibitor domain.

133 inhibitor (TFPI) contains three Kunitz-type proteinase inhibitor domains and is a potent inhibitor o

134 I, containing only the first two Kunitz-type proteinase inhibitor domains, has very little antiprolif

135 The effect of a plant proteinase inhibitor, Enterolobium contortisiliquum tryp

136 stinct from those of other classes of serine proteinase inhibitors except in the inhibitor loop; ther

137 idylarginine deiminases, kallikreins, serine proteinase inhibitor family members, Kruppel-like factor

138 pressed multifunctional member of the serine proteinase inhibitor family.

139 In addition, CPAMD8 has a Kazal-type serine proteinase inhibitor/follistatin-like domain at the C-te

140 Two hairpin-loop domains in cystatin family proteinase inhibitors form an interface surface region t

141 Purification of proteinase inhibitor from common carp (Cyprinus carpio)

142 A Beta vulgaris serine proteinase inhibitor gene (BvSTI) was fused to the const

143 n of wound-inducible H(2)O(2) generation and proteinase inhibitor gene expression by NO was not due t

144 Although the expression of proteinase inhibitor genes in response to JA was inhibit

145 tance signal for the expression of defensive Proteinase inhibitor genes.

146 in octadecanoid-based signaling of defensive proteinase inhibitor genes.

147 sidue (approximately 7.5 kDa) rapeseed class proteinase inhibitor, has been determined in solution at

148 Serine proteinase inhibitors have been reported to block host c

149 The abundant serine proteinase inhibitor heparin cofactor II (HCII) has been

150 8-OHdG) and human neutrophil elastase/alpha1-proteinase inhibitor (HNE/alpha1-PI) complex have been r

151 ectively cleaved type I gelatin and alpha(1)-proteinase inhibitor; however, it did not digest collage

152 Proteinase inhibitor I (Inh I) and proteinase inhibitor

153 In control plants, levels of proteinase inhibitor I and II proteins increased rapidly

154 ed lines contained 4- to 5-fold increases in proteinase inhibitor I and II proteins, >50% more solubl

155 The levels of proteinase inhibitor I and inhibitor II proteins in leav

156 Synthesis of proteinase inhibitor I protein in response to wounding i

157 mechanism of action of this family of serine proteinase inhibitors (I77).

158 Proteinase inhibitor I (Inh I) and proteinase inhibitor II (Inh II) from potato tubers are

159 d to analyze wound-induced expression of the proteinase inhibitor II gene in a JA biosynthetic mutant

160 is correlated with reduced expression of the proteinase inhibitor II gene in response to Botrytis and

161 y diapause suggests a possible role for this proteinase inhibitor in halting development.

162 ne- or alanine-specifically labeled alpha(1)-proteinase inhibitor in noncovalent complex with unlabel

163 AT) is the most abundantly circulating human proteinase inhibitor in the serpin family.

164 ent in the ECB saliva induce defense-related proteinase inhibitors in both tomato (PIN2) and maize (M

165 and Fabaceae, results in the accumulation of proteinase inhibitors in leaves of all three species.

166 njunction with an up-regulation of genes for proteinase inhibitors, in particular those containing th

167 he activity of caspases was elevated without proteinase inhibitors; in contrast, caspases were not ac

168 ysins by a process resistant to a mixture of proteinase inhibitors, including aprotinin, BB-94, pepst

169 Serine proteinase inhibitors, including plasminogen activator i

170 cture, cell wall thickening, accumulation of proteinase inhibitors, induction of anthocyanins, and ro

171 Specific cysteine proteinase inhibitors interrupted invasion by tachyzoite

172 The serpin family of serine proteinase inhibitors is a mechanistically unique class

173 pathway inhibitor-2 (TFPI-2), a broad range proteinase inhibitor, is highly expressed in low-grade g

174 s to the previously identified cell-secreted proteinase inhibitor known as protease nexin-2 (PN2).

175 of AbetaPP that contain a Kunitz-type serine proteinase inhibitor (KPI) domain are expressed in brain

176 -2/AbetaPP, but not its isolated Kunitz-type proteinase inhibitor (KPI) domain, in a saturable, dose-

177 the SPINK5 gene, which encodes the putative proteinase inhibitor LEKTI.

178 disease (SPINK5) encodes a 15-domain serine proteinase inhibitor (LEKTI) which is expressed in epith

179 The sugar beet serine proteinase inhibitor may be more effective for insect co

180 a cysteine proteinase, instead of a cysteine proteinase inhibitor, may be a novel insect defense mech

181 luding DEFB4 (defensin B4), SERPINB3 (serine proteinase inhibitor, member 3), STAT1 (signal transduce

182 nsistent with its proposed role in signaling proteinase inhibitor mRNA and protein synthesis.

183 eolytic activity was blocked by the cysteine proteinase inhibitor N-alpha-p-tosyl-L-lysine chlorometh

184 We recently reported a Kunitz-type proteinase inhibitor, named NaStEP (for Nicotiana alata

185 e plasminogen activator (tPA) and the serine proteinase inhibitor neuroserpin are both expressed in a

186 The alkaline proteinase inhibitor of Pseudomonas aeruginosa (APRin),

187 Alkaline proteinase inhibitor of Pseudomonas aeruginosa is a 11.5

188 II (Inh II) from potato tubers are effective proteinase inhibitors of chymotrypsin and trypsin.

189 een S195A or S195A/D189S trypsin and protein proteinase inhibitors of different structural families a

190 Many serine proteinase inhibitors of the serpin superfamily have evo

191 Addition of alpha1-proteinase inhibitor or a urokinase-type PA inhibitor, 7

192 f LapA was not sufficient to induce Pin (Ser proteinase inhibitor) or PPO (polyphenol oxidase) transc

193 )-Antichymotrypsin is a member of the serine proteinase inhibitor, or serpin, family that typically f

194 ursors is believed to be regulated by serine proteinase inhibitors, or serpins.

195 reconfigurations to produce toxic compounds, proteinase inhibitors, oxidative enzymes, and behavior-m

196 Addition of the broad-spectrum serine proteinase inhibitor, p-aminobenzamidine, or the specifi

197 ynthesized by linking the microbial aspartic proteinase inhibitor pepstatin to mannosylated BSA via a

198 The results show that a wide range of proteinase inhibitors (phenylmethanesulfonyl fluoride, N

199 und-induced systemic expression of defensive proteinase inhibitor (PI) genes in tomato plants require

200 JA accumulation and expression of defensive proteinase inhibitor (PI) genes, which were induced in m

201 Levels of granzyme B (GB) mRNA (P=0.002) and proteinase inhibitor (PI)-9 mRNA (P=0.01) in urinary cel

202 Serine proteinase inhibitor (PI)-9 with a reactive center P1 (G

203 site of what has been observed for defensive proteinase inhibitors (PIs) in other plants (typically h

204 s local and systemic expression of defensive proteinase inhibitors (PIs) in response to wounding.

205 ecular mass 44 kDa), and the serpin alpha(1)-proteinase inhibitor Pittsburgh (alpha(1)PI Pittsburgh)

206 ue-selectively (15)N-labeled serpin alpha(1)-proteinase inhibitor (Pittsburgh variant with stabilizin

207 dy was to investigate the role of the serine proteinase inhibitor plasminogen activator inhibitor -1

208 at sodium dodecyl sulfate induces the serine proteinase inhibitor, plasminogen activator inhibitor ty

209 The serine proteinase inhibitor, plasminogen activator inhibitor ty

210 In this study we have analyzed two proteinase inhibitors, plasminogen activator inhibitor t

211 nces obtained indicated that the pepper leaf proteinase inhibitors (PLPIs) exhibit homology to two Ge

212 Host proteinase inhibitors potentially contribute to immunity

213 whilst the plasma deficiency of an important proteinase inhibitor predisposes to emphysema.

214 roglobulin (alpha(2)M) is a highly conserved proteinase inhibitor present in human plasma at high con

215 Thus, the proteinase inhibitors prevent adhesion molecules such as

216 In conclusion, the plasma proteinase inhibitors prevent degradation of extracellul

217 We therefore conclude that the STCs are proteinase inhibitors, probably restricted in specificit

218 eas levels of mRNA encoding a related serine proteinase inhibitor, proteinase inhibitor 8, were unaff

219 ith the loss of accumulation of JA-regulated proteinase inhibitor proteins in reproductive tissues.

220 o plants, induces the synthesis of defensive proteinase inhibitor proteins in the treated plants and

221 ion of both hydrogen peroxide (H(2)O(2)) and proteinase inhibitor proteins in tomato leaves in respon

222 mall (approximately 6,000 D) wound-inducible proteinase inhibitor proteins were isolated from leaves

223 cells and induce the synthesis of defensive proteinase inhibitor proteins when supplied at fmol leve

224 onical conformation" typical of small serine proteinase inhibitor proteins, which explains why it ret

225 epresentative of three gene classes encoding proteinase inhibitor proteins, with distinct spatial exp

226 peptides activate the synthesis of defensive proteinase-inhibitor proteins in a manner similar to tha

227 Proteinase inhibitors provide a means of engineering pla

228 HIV proteinase inhibitors reduce the levels of Leishmania pa

229 let transmigration by using a small molecule proteinase inhibitor restores beta cell functionality, i

230 Among proteinase inhibitors screened, only decanoyl-Arg-Val-Ly

231 acy of a novel nontoxic viral-derived serine proteinase inhibitor (SERP-1) in preventing postangiopla

232 ) and its SDS-stable complex with the serine proteinase inhibitor (serpin) alpha(1)-antichymotrypsin

233 Kallistatin is a unique serine proteinase inhibitor (serpin) and a heparin-binding prot

234 wed that GCET1 has a highly conserved serine proteinase inhibitor (SERPIN) domain and is located on a

235 Members of the serine proteinase inhibitor (serpin) family play important role

236 C1 inhibitor (C1INH), a member of the serine proteinase inhibitor (serpin) family, is an inhibitor of

237 tichymotrypsin (ACT), a member of the serine proteinase inhibitor (serpin) family.

238 The activity of the serine proteinase inhibitor (serpin) plasminogen activator inhi

239 evels of kallistatin, a member of the serine proteinase inhibitor (SERPIN) superfamily with antiangio

240 n member of the high molecular weight serine proteinase inhibitor (serpin) superfamily, we initiated

241 Kallistatin is a serine proteinase inhibitor (serpin) that specifically inhibits

242 Headpin is a novel serine proteinase inhibitor (serpin) with constitutive mRNA exp

243 An amyloid-associated serine proteinase inhibitor (serpin), alpha(1)-antichymotrypsin

244 Kallistatin, a serine proteinase inhibitor (serpin), is expressed in the endot

245 Kallistatin is a heparin-binding serine proteinase inhibitor (serpin), which specifically inhibi

246 binding protein, semaphorin, and five serine proteinase inhibitors (serpins).

247 members of a family of intracellular serine proteinase inhibitors (serpins).

248 Treatment of the Ddi1 transformants with HIV proteinase inhibitors showed differential effects depend

249 lic Acid Insensitive (SlGAI) and Cathepsin D Proteinase Inhibitor (SlPI) differed significantly in th

250 se phosphatase 1 (MKP-1) and secretory leuko-proteinase inhibitor (SLPI) gene induction.

251 Secretory leukocyte proteinase inhibitor (SLPI) is a major serine proteinase

252 Secretory leukocyte proteinase inhibitor (SLPI) is a well-established inhibi

253 surface liquid, namely, secretory leukocyte proteinase inhibitor (SLPI), lysozyme, and lactoferrin.

254 inhibitor-like (TIL) domains of small serine proteinase inhibitors (smapins).

255 surface architecture of the soybean cysteine proteinase inhibitor (soyacystatin N, scN) was engineere

256 attributable to increased luminal levels of proteinase inhibitors such as alpha1-anti-trypsin.

257 The use of proteinase inhibitors such as gabexate mesylate in the p

258 Our data are the first to identify STC1 as a proteinase inhibitor, suggesting a previously unrecogniz

259 rotein is dramatically increased by cysteine proteinase inhibitors, suggesting rapid turnover, and is

260 Members of the serpin (serine proteinase inhibitor) superfamily play a central role in

261 s a dual role in potato plants in regulating proteinase inhibitor synthesis in leaves in response to

262 hydrogen peroxide (H(2)O(2)) production and proteinase inhibitor synthesis that was induced by syste

263 not blocked by NO, nor was H(2)O(2)-induced proteinase inhibitor synthesis.

264 way inhibitor (TFPI) is a Kunitz-type serine proteinase inhibitor that down-regulates tissue factor-i

265 tion by heparin cofactor II (HCII), a plasma proteinase inhibitor that has been detected within the a

266 oem serpin-1 (CmPS-1), a novel 42-kDa serine proteinase inhibitor that is developmentally regulated a

267 ), which encodes for a broad-spectrum serine proteinase inhibitor that negatively regulates the extra

268 athway inhibitor-2 (TFPI-2) is a Kunitz-type proteinase inhibitor that regulates a variety of serine

269 or clear zone that corresponded to the BvSTI proteinase inhibitor that was not detected in the untran

270 -Macroglobulin (alpha2M) is a broad spectrum proteinase inhibitor that when activated by proteinases

271 ne-use suicide substrate serine and cysteine proteinase inhibitors that have evolved to finely regula

272 ete inflammatory cytokines, proteinases, and proteinase inhibitors that influence extracellular matri

273 a 72-kd member of the serpin superfamily of proteinase inhibitors that produces rapid inhibition of

274 heat shock proteins, and secretory leukocyte proteinase inhibitors that protect the integrity of the

275 stically unique class of naturally occurring proteinase inhibitors that trap target enzymes as stable

276 Without proteinase inhibitors, the extracellular matrix was degr

277 We report here that the serine proteinase inhibitor tissue factor pathway inhibitor-2 (

278 e volatile (E)-alpha-bergamotene and trypsin proteinase inhibitors (TPIs), which are also found in he

279 r leaves typically invoke a higher defensive proteinase inhibitor transcript accumulation than older

280 Serpin family protein proteinase inhibitors trap proteinases at the acyl-inter

281 xhibit cleavage of Dsg1, which is blocked by proteinase inhibitor treatment as well as by siRNA silen

282 e named trespin (TGF-beta-repressible serine proteinase inhibitor (trespin).

283 proteinase by two standard mechanism serine proteinase inhibitors, turkey ovomucoid third domain (OM

284 ed a severe reduction in the accumulation of proteinase inhibitors under salt stress, indicating that

285 This enabled us to construct an alpha1-proteinase inhibitor variant (Ile-Lys-Pro-Arg-/-Ser-Ile-

286 covalent complexation between PR3 and alpha1-proteinase inhibitor was delayed in the presence of MCPR

287 adruple-PM KOs to six different HIV aspartic proteinase inhibitors was comparable to that of 3D7, thu

288 ing that salt stress-induced accumulation of proteinase inhibitors was jasmonic acid dependent.

289 The antiapoptotic effect conferred by the proteinase inhibitors was proportional to proteinase inh

290 ed in medium containing serum from which the proteinase inhibitors were removed.

291 Two genes encoding cystatins, cysteine proteinase inhibitors, were cloned from the flesh fly Sa

292 In the absence of the proteinase inhibitors, Western blot analysis shows that

293 members of the serpin superfamily of serine proteinase inhibitors, which are best recognized for the

294 a member of the serpin superfamily of serine proteinase inhibitors, which function in maintaining hom

295 may be a naturally occurring neuroprotective proteinase inhibitor, whose therapeutic administration d

296 itor of the Wnt pathway, SERPINA3K, a serine proteinase inhibitor with anti-inflammatory and angiogen

297 epithelium-derived factor (PEDF) is a serine proteinase inhibitor with antiangiogenic activities.

298 DeltaGD)) complexed with protein Z-dependent proteinase inhibitor (ZPI).

299 ted with the corresponding loops of alpha(1)-proteinase inhibitor (ZPI-CD-helix(alpha1-PI)).

300 p of the non-heparin-binding serpin alpha(1)-proteinase inhibitor (ZPI-D-helix(alpha1-PI)).