ライフサイエンスコーパス: proteinosis

1 dysfunctional, resembling pulmonary alveolar proteinosis.

2 herosclerotic lesions and pulmonary alveolar proteinosis.

3 patients with idiopathic pulmonary alveolar proteinosis.

4 actant clearance, causing pulmonary alveolar proteinosis.

5 olated from patients with pulmonary alveolar proteinosis.

6 ore represent a recurrent mutation in lipoid proteinosis.

7 or to the pathogenesis of pulmonary alveolar proteinosis.

8 st common sites for ECM1 mutations in lipoid proteinosis.

9 nflammation leading to fibrosis and alveolar proteinosis.

10 nic inflammation, and two had focal alveolar proteinosis.

11 ng function that prevents pulmonary alveolar proteinosis.

12 ventilatory defects 63%, pulmonary alveolar proteinosis 18%, pulmonary arterial hypertension 9%), de

13 studied 12 subjects with pulmonary alveolar proteinosis, 61 healthy control subjects, and 12 control

14 disorder similar to human pulmonary alveolar proteinosis, a rare disease with congenital, infantile,

15 om healthy donors and patients with alveolar proteinosis also binds to M.tb.

16 ar macrophages, thereby underlying pulmonary proteinosis and airborne infections, type I interferon v

17 t GM-CSF signaling caused pulmonary alveolar proteinosis and excessive IL-6 signaling promoted bone m

18 impaired in patients with pulmonary alveolar proteinosis and that GM-CSF autoantibodies cause the dys

19 e, cigarette smoking, and pulmonary alveolar proteinosis and the implications of obesity and obstruct

20 s infections, lymphedema, pulmonary alveolar proteinosis, and myelodysplasia.

21 ytogenetic abnormalities, pulmonary alveolar proteinosis, and myeloid leukemias.

22 lerosis, type 2 diabetes, pulmonary alveolar proteinosis, and obesity, have a chronic inflammatory co

23 ssion profile of a variant causal for lipoid proteinosis, and with a simulation study to assess our m

24 Autoimmune pulmonary alveolar proteinosis (aPAP) is a rare lung disorder involving pro

25 s against GM-CSF underlie pulmonary alveolar proteinosis; associated infections are less well charact

26 h failure, renal disease, pulmonary alveolar proteinosis, autoimmune disorders and osteoporosis, are

27 SF and IL-3 and developed pulmonary alveolar proteinosis because of elimination of mouse GM-CSF.

28 d to the pathogenesis of congenital alveolar proteinosis (CAP).

29 crine syndrome type I and pulmonary alveolar proteinosis, detecting ACAA levels consistent with those

30 pe of decreased GM-CSF function is pulmonary proteinosis due to aberrant function of alveolar macroph

31 respiratory infections and develop alveolar proteinosis due to defects in innate immune function and

32 al amygdala pathology as a sequela of lipoid proteinosis due to Urbach-Wiethe disease.

33 d cell debris in airways (pulmonary alveolar proteinosis) due to impaired development of alveolar mac

34 Prdx6 and SP-A isolated from human alveolar proteinosis fluid were studied.

35 ophils from subjects with pulmonary alveolar proteinosis had normal ultrastructure and differentiatio

36 Hereditary pulmonary alveolar proteinosis (hPAP) caused by granulocyte-macrophage colo

37 r identical to hereditary pulmonary alveolar proteinosis (hPAP) in children with CSF2RA or CSF2RB mut

38 resulting in complete correction of alveolar proteinosis in bitransgenic GM-/-, SP-C-GM+ mice.

39 al and prevented the development of alveolar proteinosis in mice transplanted with GM-Csf-receptor-de

40 by homologous recombination caused alveolar proteinosis in mice.

41 ronic interstitial inflammation and alveolar proteinosis, inflammation of the glandular stomach and s

42 Idiopathic pulmonary alveolar proteinosis is caused by autoantibodies against granuloc

43 However, lipoid proteinosis is clinically heterogeneous with affected in

44 ice lacking beta c show a pulmonary alveolar proteinosis-like disease and reduced numbers of peripher

45 Lipoid proteinosis (LP), also known as hyalinosis cutis et muco

46 uman SP-A (isolated from normal and alveolar proteinosis lungs) and SP-D (recombinant protein and pro

47 t protein and protein isolated from alveolar proteinosis lungs) bound the conidia.

48 itis obliterans (n = 21), pulmonary alveolar proteinosis (n = 12), pulmonary fibrosis (n = 15), and o

49 ccupational burden, 30%); pulmonary alveolar proteinosis (occupational burden, 29%); tuberculosis (oc

50 nfection in patients with pulmonary alveolar proteinosis occurs in association with high levels of au

51 B, and C in lavage fluids from patients with proteinosis of different causes in comparison with healt

52 for later development of pulmonary alveolar proteinosis or other opportunistic infections, and that

53 impaired in patients with pulmonary alveolar proteinosis, owing to the presence of GM-CSF autoantibod

54 t it is elevated in human pulmonary alveolar proteinosis (PAP) and in the GM-CSF knockout mouse, a mu

55 respectively) resulted in pulmonary alveolar proteinosis (PAP) but no hematologic abnormalities.

56 frequency and features of pulmonary alveolar proteinosis (PAP) in patients with ADA deficiency.

57 Pulmonary alveolar proteinosis (PAP) is a devastating lung disease caused b

58 Pulmonary alveolar proteinosis (PAP) is a rare disease characterized by an

59 Autoimmune pulmonary alveolar proteinosis (PAP) is a rare disease characterized by mye

60 Pulmonary alveolar proteinosis (PAP) is a rare disease with frequently favo

61 Pulmonary alveolar proteinosis (PAP) is a rare disorder in which surfactant

62 Pulmonary alveolar proteinosis (PAP) is a rare lung disease characterized b

63 Pulmonary alveolar proteinosis (PAP) is a rare lung disorder in which surfa

64 Pulmonary alveolar proteinosis (PAP) is a rare lung syndrome caused by the

65 Pulmonary alveolar proteinosis (PAP) is a rare syndrome characterized by ac

66 Primary pulmonary alveolar proteinosis (PAP) is a rare syndrome characterized by ac

67 Pulmonary alveolar proteinosis (PAP) is a syndrome characterized by the acc

68 Pulmonary alveolar proteinosis (PAP) is an idiopathic lung disease in which

69 Rationale: Pulmonary alveolar proteinosis (PAP) is characterized by filling of the alv

70 upus erythematosus (SLE), pulmonary alveolar proteinosis (PAP) or multiple sclerosis) and coronavirus

71 In patients with pulmonary alveolar proteinosis (PAP) syndrome, disruption of granulocyte/ma

72 dies are thought to cause pulmonary alveolar proteinosis (PAP), a rare syndrome characterized by myel

73 phy is characteristic for pulmonary alveolar proteinosis (PAP), it is not specific and has not been c

74 independent kindreds have pulmonary alveolar proteinosis (PAP), progressive polycystic lung disease,

75 how its disruption causes pulmonary alveolar proteinosis (PAP), we evaluated lipid composition in alv

76 ells and severe secondary pulmonary alveolar proteinosis (PAP).

77 gitis who later developed pulmonary alveolar proteinosis (PAP).

78 l function in patients with primary alveolar proteinosis (PAP).

79 a slightly more severe mucocutaneous lipoid proteinosis phenotype, but neurological features do not

80 The autosomal recessive disorder lipoid proteinosis results from mutations in extracellular matr

81 f extracts from normal human skin and lipoid proteinosis skin (lacking ECM1).

82 hat partially rescued the pulmonary alveolar proteinosis syndrome.

83 s, distinguishing the disorder from alveolar proteinosis syndromes.

84 in 10 further unrelated patients with lipoid proteinosis to extend genotype-phenotype correlation and

85 unction characteristic of pulmonary alveolar proteinosis was reproduced in a dose-dependent fashion i

86 larities between lichen sclerosus and lipoid proteinosis, which results from mutations in extracellul

87 t5 signaling in AMs, mice developed alveolar proteinosis with altered lipid homeostasis.

88 Five patients developed pulmonary alveolar proteinosis without mutations in the granulocyte-macroph