ライフサイエンスコーパス: proteolytically

1 h mature dimeric growth factors are released proteolytically.

2 subset of the CP N-terminal regions becomes proteolytically accessible in the expanded form, althoug

3 in L (Cat L) is a cysteine protease that can proteolytically activate CCAAT displacement protein/cut

4 ains of Coa and vWbp associate with, and non-proteolytically activate prothrombin.

5 Prostasin is unable to proteolytically activate the matriptase zymogen directly

6 AP301 increased current in proteolytically activated (cleaved) but not near-silent

7 Mammalian SREBPs are proteolytically activated and liberated from the membran

8 d) with bovine Pg than with human Pg and non-proteolytically activated bovine but not human Pg.

9 muscle cells generated pro-MMP-1, which was proteolytically activated by mast cell tryptase.

10 -activated receptor 1 (PAR1) is irreversibly proteolytically activated by thrombin.

11 uced degradation of the cell surface pool of proteolytically activated ENaC, which enhanced its recyc

12 t here the 2.3 A resolution structure of the proteolytically activated form of Cry5B.

13 tA pro-protein was compared with that of the proteolytically activated protein and with E. coli TatA.

14 nstrating that the activity of many of these proteolytically activated protein fragments can be atten

15 To initiate signaling, pro-HGF must be proteolytically activated to reveal a secondary Met bind

16 -coupled receptor (GPCR) for thrombin and is proteolytically activated, similar to the prototypical P

17 A is produced as a proprotein, which must be proteolytically activated; generally, cell surface activ

18 PAR1 is proteolytically-activated by bloodstream serine protease

19 We discovered that MBTPS1/SKI-1/S1P, which proteolytically activates a class of transmembrane trans

20 eptors (NLRs) whose stimulation recruits and proteolytically activates caspase-1 within the inflammas

21 In particular, MMP-8 proteolytically activates IL-8 and, thereby, regulates n

22 MMP-1 proteolytically activates protease activated receptor-1

23 The inflammatory mediator thrombin proteolytically activates protease-activated receptor (P

24 Proteolytically active ADAM (named for "a disintegrin an

25 Proteolytically active ADAMs are responsible for ectodom

26 , like the human orthologue HtrA1, BbHtrA is proteolytically active against numerous extracellular pr

27 dings provide a mechanism for explaining how proteolytically active allergens could preferentially in

28 These events are further amplified by proteolytically active allergens through digestion of ce

29 s promote assembly of inactive hexamers into proteolytically active cages with 12, 18, 24, or 30 subu

30 4 days p.i.) harboring NMI or NMII contained proteolytically active cathepsins and quickly degraded E

31 ot be accurately measured immunologically in proteolytically active CF secretions; mucins are hyperco

32 of Oma1 impair its ability to form a labile proteolytically active complex in response to stress sti

33 erine protease factor VIIa (FVIIa) to form a proteolytically active complex that can trigger coagulat

34 thout inducing apoptosis by functioning in a proteolytically active complex with FLICE-like inhibitor

35 C4b provides a platform for assembly of the proteolytically active convertases that mediate downstre

36 idermis: a one-chain zymogen and a two-chain proteolytically active form, generated by matriptase-dep

37 n and transformation of plasminogen into its proteolytically active form, plasmin, enhances the abili

38 Purified PcADAMp protein was proteolytically active in casein zymography, requiring d

39 active intermediate, prethrombin; or (2) the proteolytically active intermediate, meizothrombin (fIIa

40 es cargo degradation by enabling fusion with proteolytically active lysosomes enriched in the soma.

41 Proteolytically active meprinalpha leads to an increase

42 1 is secreted as a mature, glycosylated, and proteolytically active metalloprotease, capable of cleav

43 ADAMDEC1 is a proteolytically active metzincin metalloprotease display

44 Ectopic expression of proteolytically active MMP3 in mouse mammary epithelia t

45 1-MMP promotes tumor growth in vivo, whereas proteolytically active MT1-MMP devoid of cytoplasmic tai

46 s a distinctive "molecular signature" of the proteolytically active MT1-MMP.

47 Proteolytically active MVs induced by tobacco smoke may

48 esults in disassembly, ensuring that DegP is proteolytically active only when sufficient quantities o

49 in plasma as a zymogen and when converted to proteolytically active plasmin dissolves preformed fibri

50 MBP in shiverer mice and mutagenesis of the proteolytically active site in MBP or of the MBP cleavag

51 trate binding converts inactive trimers into proteolytically active trimers, and simultaneously leads

52 ritance is important for rapid generation of proteolytically active vacuolar compartments in daughter

53 ay but that NETs produced by all stimuli are proteolytically active, kill bacteria and composed mainl

54 g320 by the prothrombinase complex generates proteolytically active, meizothrombin (MzT), followed by

55 ell invasion when CTSB was overexpressed and proteolytically active.

56 The oligomers were unimolecular and proteolytically active.

57 may provide a generic approach for designing proteolytically-actuated peptides for tumor-penetrative

58 These proteins are presumed to be trimmed proteolytically and undergo posttranslational modificati

59 mitochondrion and found that it is processed proteolytically at a WGSS cleavage site into a heterodim

60 in cleavage of the activation peptide or non-proteolytically by exposure to 50 mM Ca2+.

61 Factor XIII can be activated proteolytically by thrombin cleavage of the activation p

62 hat is both dependent upon the presence of a proteolytically cleavable propeptide and sensitive to wa

63 ngth Reelin and its N-terminal fragment N-R6 proteolytically cleave L1 to generate an L1 fragment wit

64 intracellular and extracellular enzymes that proteolytically cleave proBDNF furin and tissue plasmino

65 The ectodomain is proteolytically cleaved (S1) in response to ligand-induc

66 VEGFC and VEGFD are proteolytically cleaved after cell secretion in vitro, a

67 ide peptidases, as well as proteins that are proteolytically cleaved after cisplatin-induced apoptosi

68 In this study, we demonstrated that GAB1 was proteolytically cleaved after CVB3 infection at G175 and

69 roteins (ZP1, ZP2, and ZP3), of which ZP2 is proteolytically cleaved after gamete fusion to prevent p

70 proDrICE was proteolytically cleaved and activated during infection.

71 Under low oxygen, Sre1 is proteolytically cleaved and the N-terminal transcription

72 Under low oxygen, Sre1 is proteolytically cleaved and the released N-terminal tran

73 PC1 must also be proteolytically cleaved at a GPS site for this to occur.

74 Here we show that histone H3 is proteolytically cleaved at its N-terminus during ESC dif

75 expressed, transported to cell surfaces, and proteolytically cleaved at levels comparable to that of

76 In some cases, the S protein is proteolytically cleaved at the S1-S2 boundary.

77 Since PKCdelta can be proteolytically cleaved by caspase-3 during apoptosis, t

78 The ectodomain of TLR9 must be proteolytically cleaved by endosomal proteases to produc

79 Many guidance receptors are proteolytically cleaved by membrane-associated metallopr

80 is synthesized as a large precursor that is proteolytically cleaved by OGT, which may regulate its b

81 f extracellular matrix remodeling, whereby a proteolytically cleaved CDCP1 regulates in vivo locomoti

82 or Escherichia coli DH5alpha showed that Cpa proteolytically cleaved complement components C3, C3a, a

83 Proteolytically cleaved CP subunits dissociate from the

84 their interaction with factor I and C3b, the proteolytically cleaved form of C3.

85 ncreased levels of the catalytically active, proteolytically cleaved form of CatD, corresponding with

86 ow that TLR9(471-1032), corresponding to the proteolytically cleaved form, does not function on its o

87 Both proteins bound to three of the four proteolytically cleaved fragments of MSP1 (p42, p38, and

88 f the constituent components are released as proteolytically cleaved fragments.

89 ich promotes callus formation in culture, is proteolytically cleaved from its precursor by a specific

90 normal tissues and cell lines, the kinase is proteolytically cleaved from the channel domain in a cel

91 In humans, proteolytically cleaved HCII forms were detected during

92 that HAH autoantibodies selectively bind to proteolytically cleaved IgGs and can thereby provide a s

93 inogen (HK) is an endogenous protein that is proteolytically cleaved in plasma and on endothelial cel

94 zymography, and Western blot, which in turn proteolytically cleaved in situ the Abeta peptides.

95 oposed that a significant fraction of APP is proteolytically cleaved in the neuronal soma into N- and

96 For APP to be proteolytically cleaved into Abeta, it must be internali

97 In vivo, SltB is proteolytically cleaved into its two principal domains.

98 In vivo, Slit is proteolytically cleaved into N- and C-terminal fragments

99 ANGPTL4 protein is then proteolytically cleaved into several forms by proprotein

100 atis) and C. pneumoniae, the PmpD protein is proteolytically cleaved on the cell surface.

101 ne adrenal medulla 8-22 peptide (BAM8-22), a proteolytically cleaved product of proenkephalin A, is a

102 ely, overexpression of plasmids encoding the proteolytically cleaved SIRPalpha fragments in cells res

103 tant indicates the presence of an 18-residue proteolytically cleaved species.

104 as brought iRGD to the tumor, the peptide is proteolytically cleaved to expose the cryptic CendR moti

105 o the cytoplasm, where it accumulates and is proteolytically cleaved to form C-terminal fragments.

106 The amyloid precursor protein (APP) is proteolytically cleaved to generate beta-amyloid (Abeta)

107 lagen XV/XVIII, a matrix protein that can be proteolytically cleaved to release Endostatin, an antian

108 Following secretion, ACBP is proteolytically cleaved to the active neuropeptides by p

109 e completely blocked, p120 Nrf1 can still be proteolytically cleaved to the p110 form, which is trans

110 des the glycoprotein precursor (GPC) that is proteolytically cleaved to yield two viral structural gl

111 l regulatory element-binding protein Sre1 is proteolytically cleaved under low oxygen, and its N-term

112 hybrid GPC complexes are properly assembled, proteolytically cleaved, and transported to the cell sur

113 ulating partner mediating cross-talk between proteolytically cleaved, membrane-retained CDCP1 and mem

114 Full-length CDCP1 (flCDCP1) can be proteolytically cleaved, resulting in a cleaved membrane

115 subunit of neuronal L-type VGCCs, Cav1.2, is proteolytically cleaved, resulting in Cav1.2 fragment ch

116 T4.13, the C-terminal extension of SPI-1 was proteolytically cleaved.

117 s efficiently expressed on cell surfaces and proteolytically cleaved.

118 lular, ligand-binding portion of the pIgR is proteolytically cleaved.

119 To investigate the underlying mechanisms, we proteolytically cleaved/activated ENaC at the cell surfa

120 Whereas FI-FH proteolytically cleaves C3b into iC3b, PAM-bound hPm cat

121 Plasma kallikrein (pKal) proteolytically cleaves high molecular weight kininogen

122 ke protease, nsp5, is an IFN antagonist that proteolytically cleaves the nuclear transcription factor

123 is implicated in leukocyte transmigration by proteolytically cleaving its endothelial substrates.

124 oprotein convertase subtilisin/kexin enzymes proteolytically convert immature proproteins into bioact

125 The zymogen prothrombin is proteolytically converted by factor Xa to the active pro

126 ic proteins to autolysosomes where they were proteolytically converted into products capable of killi

127 acillus subtilis, induces plasma clotting by proteolytically converting ProT into active sigmaPre2, a

128 damaged fibers are repaired longer, whereas proteolytically damaged fibers are repaired shorter, rel

129 ascular cells encapsulated in cell-adhesive, proteolytically-degradable poly(ethylene) glycol-based h

130 MMP-9 was confirmed in vitro and in vivo to proteolytically degrade CD36.

131 ite stages of Leishmania species bind to and proteolytically degrade FN at the parasite surface and d

132 ase activity, active serine proteases, which proteolytically degrade NET-associated proteins and prom

133 During stress, DinJ is proteolytically degraded and free YafQ halts translation

134 contain stoichiometric flavin, type 1 CRY is proteolytically degraded by a light-initiated reaction i

135 nt evidence that like lambda CII, 186 CII is proteolytically degraded in vivo, but unlike lambda CII,

136 hexylamine, lysine-containing peptides, or a proteolytically degraded protein, it bound to MDA-modifi

137 ence of its partner protein, SleB or YpeB is proteolytically degraded soon after expression during sp

138 dividual subunits of fatty acid synthase are proteolytically degraded when the respective partner is

139 posed that the protein component of a DPC is proteolytically degraded, giving rise to smaller DNA-pep

140 with natriuretic peptide receptors and to be proteolytically degraded.

141 to and merge with the vacuole, where A30P is proteolytically degraded.

142 Cathepsin B (CatB) proteolytically degrades Abeta into non-aggregating frag

143 ClpP proteolytically degrades folded proteins only when assoc

144 omplex consists of a core particle (CP) that proteolytically degrades polyubiquitylated proteins, and

145 ne proteinase, is activated during aging and proteolytically degrades tau, abolishes its microtubule

146 leviates DIAP1 inhibition of all caspases by proteolytically degrading DIAP1 and induces apoptosis bo

147 ), a specialized group of enzymes capable of proteolytically degrading extracellular matrix proteins,

148 part, on the basis of work conducted with a proteolytically derived form of phosphorylase that lacke

149 trafficking by secreting a peptide (PEPITEM) proteolytically derived from 14.3.3 zeta delta (14.3.3.z

150 hydrogen-deuterium exchange patterns within proteolytically derived peptides allows spatial resoluti

151 For this protocol, proteins can be proteolytically digested before ETD analysis, although d

152 employed for isolating phosphopeptides from proteolytically digested plasma membranes of Arabidopsis

153 he peptide harboring the FLNH(2) can then be proteolytically digested, purified by HPLC and then iden

154 quantitation of CFTR peptides produced from proteolytically digesting the plasma membrane subproteom

155 Thus, a proteolytically diverse portfolio exists for MT1-MMP wit

156 During a proteolytically-driven maturation process, the orthoretr

157 s could restore immune effector functions to proteolytically generated F(ab')2 fragments.

158 arallel experiments, we showed that the same proteolytically generated Fabs and F(ab')(2)s become sel

159 Using proteolytically generated Fn fragments and purified reco

160 ctive band that corresponds to PKMalpha, the proteolytically generated, free catalytic subunit of PKC

161 GerD-FLAG was not processed proteolytically in a B. subtilis strain lacking gerF (lg

162 s down the complex that produces thrombin by proteolytically inactivating factor Va.

163 A proteolytically inactive form of APC with reduced antico

164 We generated two proteolytically inactive Lon mutants, S679A and S679W, w

165 We report that iRhom2 (RHBDF2), a proteolytically inactive member of the rhomboid family,

166 Proteolytically inactive MT1-MMP promotes tumor growth i

167 , in vitro transcribed mRNA, which encodes a proteolytically inactive Papp-a mutant, recues the papp-

168 Proteolytically inactive prostasin, unlike the wild-type

169 pancreatic trypsin inhibitor (BPTI) with the proteolytically inactive rat trypsin mutant S195A.

170 overexpression of wild-type YME1L but not a proteolytically inactive YME1L variant.

171 otein quality control but are presumed to be proteolytically inactive.

172 In contrast, this domain remains proteolytically labile in cells producing only one of th

173 Using trypsin proteolysis, we identified the proteolytically labile sites in the C-terminal domain (a

174 nt in the egg as well as that of its derived proteolytically modified fragments necessary for develop

175 MSP1 is extensively proteolytically modified, first just before egress and t

176 the final stages of merozoite development to proteolytically modify the SERA family of papain-like pr

177 Calpain enzymes proteolytically modulate cellular function and have been

178 hydrolytically, whereas natural ECM degrades proteolytically, often through matrix metalloproteinases

179 ates: in its unmodified quiescent form, in a proteolytically "on" state induced by ethylenediaminetet

180 Diminished binding of soluble hTSP-1 to proteolytically pretreated staphylococci suggested a pro

181 hat they can do so after the glycoprotein is proteolytically primed and bound to its intracellular re

182 s reach an endosomal compartment where GP is proteolytically primed by cathepsins.

183 GP(1) and GP(2) that remain after GP(1,2) is proteolytically primed by endosomal cathepsins for fusio

184 y, and neutralize viral entry by targeting a proteolytically primed, fusion-competent GP intermediate

185 t with a model that the amon protein acts to proteolytically process a diverse suite of peptide hormo

186 ppropriate spatiotemporal pattern in vivo to proteolytically process Cad6B.

187 ive temperature, MHV-Brtsc31 was not able to proteolytically process either p150, the precursor polyp

188 l analysis that proprotein convertases (PCs) proteolytically process human Pxdn at Arg-1336, a locati

189 However, calpains can proteolytically process PKCs, and the potential in vivo

190 or Ebola virus infection and are believed to proteolytically process the Ebola virus glycoprotein (GP

191 BclA contains a proteolytically processed 38-residue amino-terminal doma

192 In response to CpG DNA stimulation, the proteolytically processed 80-kDa fragment is tyrosine ph

193 ocess is known to decrease the expression of proteolytically processed active channels on the cell su

194 inal mitochondrial targeting peptide that is proteolytically processed after import into the mitochon

195 bilized from the ER to the Golgi where it is proteolytically processed and released to enter the nucl

196 Endocytosed antigens are proteolytically processed and small amounts of peptides

197 Here, we show that hTLR7 is proteolytically processed and that the C-terminal fragme

198 Upon heat stress, AtBAG7 is sumoylated, proteolytically processed and translocated from the ER t

199 In contrast, proteolytically processed ARSG fragments of 34-, 18-, an

200 is study indicates that C. abortus Pmp18D is proteolytically processed at the cell surface similar to

201 nd SprE may modify the cell wall affinity of proteolytically processed AtlA resulting in either a pro

202 ns, adhesins, and proteases, are extensively proteolytically processed both pre- and postexocytosis.

203 We show that although the S1/S2 site is proteolytically processed by furin during protein biosyn

204 polyposis coli (APC), and GSK3beta were also proteolytically processed by P. gingivalis gingipains.

205 Upon migration to the Golgi, bZIP28 is proteolytically processed by proteases S1P and S2P.

206 Fpr1 is secreted and proteolytically processed by the fungus.

207 h the nucleocapsids of some PEDV strains are proteolytically processed by the virally encoded main pr

208 ncode large replicase polyproteins which are proteolytically processed by viral proteases to generate

209 ssion of a lantibiotic-type bacteriocin, but proteolytically processed derivatives of the phenol-solu

210 ay requires a signaling complex in which the proteolytically processed distal C-terminal domain acts

211 binds to cell-surface receptors and is then proteolytically processed forming a LF-binding competent

212 y, our study identifies histone H3.3 and its proteolytically processed forms as key regulators of cel

213 mineralization of bone and dentin, exists as proteolytically processed fragments in the mineralized t

214 composed of full-length PmpD (p155) and two proteolytically processed fragments, the p73 passenger d

215 e functional region for CLV3, and that it is proteolytically processed from the CLV3 precursor protei

216 The octapeptide angiotensin II (AII) is proteolytically processed from the decapeptide AI by ang

217 l nsp1 in these processes, using nsp1beta, a proteolytically processed functional product of nsp1 as

218 and lymphangiogenic glycoprotein that can be proteolytically processed generating various forms diffe

219 ARSG is expressed and proteolytically processed in a tissue-specific manner.

220 The TLR9-GFP transgene is functional and is proteolytically processed in resting bone marrow-derived

221 asmic reticulum (ER), and is transported and proteolytically processed in the Golgi apparatus under c

222 he distal portion of the C terminus (DCT) is proteolytically processed in vivo and serves as a noncov

223 Progranulin is proteolytically processed into granulins, but the role o

224 as an inactive proenzyme (pro-TPP1) that is proteolytically processed into the active enzyme after e

225 In human skin, CHGA was found to be proteolytically processed into the antimicrobial fragmen

226 (LC-MS/MS) analyses suggested that ChiA was proteolytically processed into two GH18 domain-containin

227 ic construct, it was discovered that MT1-MMP proteolytically processed the pro-fibrotic molecule, lat

228 Early during germination, YpeB is proteolytically processed to a stable fragment.

229 ute its function, the intact-Ac45 protein is proteolytically processed to cleaved-Ac45 thereby releas

230 through endosome to the lysosome where it is proteolytically processed to enzymatically active-CD.

231 Herein we report that human TLR3 is proteolytically processed to form two fragments in endos

232 nt CLEs are posttranslationally modified and proteolytically processed to function as bioactive ligan

233 RPTP-kappa is proteolytically processed to isoforms that have opposing

234 expressed as a transmembrane protein that is proteolytically processed to release a soluble form.

235 LKs are synthesized as prepro-forms that are proteolytically processed to secreted pro-forms via the

236 a is synthesized as a precursor molecule and proteolytically processed to the mature form by members

237 FV medium RNA encodes a polyprotein which is proteolytically processed to yield the glycoprotein prec

238 efficient incorporation of VP1, as well as a proteolytically processed VP1 subunit that could account

239 sp1/11(-/-) BMDC indicated that caspase-8 is proteolytically processed within detergent-insoluble ASC

240 ith pulmonary diseases, and full-length (not proteolytically processed) IL-33 is the predominant form

241 protein phosphatase PGAM5, which we show is proteolytically processed, accumulates in cytosol during

242 At red blood cell invasion MSP1 is proteolytically processed, and the 19-kDa C-terminal fra

243 The MGA0674-encoded lipoprotein is a proteolytically processed, immunogenic, TX-114 detergent

244 The proteolytically processed, mature form of pVI, protein V

245 s the ER and moves to the Golgi, where it is proteolytically processed, releasing its transcriptional

246 cA, the VacA Delta346-347 mutant protein was proteolytically processed, secreted, and bound to eukary

247 s showed that PyrR and PyrD are taken up and proteolytically processed.

248 ts C-terminus, and we demonstrate that it is proteolytically processed.

249 Additionally, we observed that Dsg2 is proteolytically processed; resulting in a 95-kDa ectodom

250 d into the parasitophorous vacuole, where it proteolytically processes a subset of parasite proteins

251 e found that the 55-kDa Tpr inactive zymogen proteolytically processes itself into active forms of 48

252 dogenous angiogenesis inhibitors but require proteolytically processing by furin to compete with VEGF

253 Kex2 and Kex1 may promote cell fusion by proteolytically processing substrates that act in parall

254 fy Cathepsin L as a protease responsible for proteolytically processing the N-terminal H3 tail.

255 Autoactivation of cationic trypsinogen is proteolytically regulated by chymotrypsin C (CTRC), whic

256 In Escherichia coli, such antitoxins are proteolytically regulated by the ATP-dependent proteases

257 ADAMTS13 proteolytically regulates the platelet-tethering functio

258 l fragment, called the PF-AB domain, becomes proteolytically released as well, but much less is known

259 Proteolytically released extracellular matrix (ECM) frag

260 Mechanistically, these studies reveal that a proteolytically released fragment of this collagen, term

261 extracellular domain of the PDGFRbeta can be proteolytically released from cell membranes and, if so,

262 Collagen XVII is proteolytically released from the membrane, and the path

263 The extent to which phage is proteolytically released from the resin was found to be

264 Proteolytically released GAGs are involved in the genera

265 4 (ErbB4) is a kinase that can signal via a proteolytically released intracellular domain (ICD) in a

266 Importantly, proteolytically released sIL-23R has IL-23 binding activ

267 the fusion protein on an amylose column, we proteolytically released the TonB C terminus and charact

268 Gag is then processed proteolytically, releasing the capsid protein (CA) to as

269 egligible binding to full-length GP, bound a proteolytically remodeled GP with picomolar affinity, su

270 ys a critical role in cancer cell biology by proteolytically remodeling the extracellular matrix.

271 portion of laminin-332, termed G45, which is proteolytically removed and absent in normal tissues, is

272 lular amino-terminal half of the protein, is proteolytically removed during prolonged zinc deficiency

273 cleaves signal peptides after they have been proteolytically removed from exported proteins by signal

274 Ripe fruit extracts proteolytically removed the NTT of 27-kD AcCYS1 in vitro

275 l extensions of the ClpP/R subunits were not proteolytically removed upon assembly, suggesting a regu

276 ion of a SIRPalpha mutant plasmid encoding a proteolytically resistant form in HeLa cells inhibited a

277 Being proteolytically resistant, D-peptides lack interactions

278 Cytidylyltransferase (CCTalpha) is a proteolytically sensitive lipogenic enzyme containing an

279 forms a beta-barrel when expressed alone or proteolytically separated from the NTD, indicating that

280 e heparan sulfate proteoglycan syndecan-1 is proteolytically shed from the surface of multiple myelom

281 ting enzyme (TACE, herein denoted as Adam17) proteolytically sheds several cell-surface inflammatory

282 uch peptides, which are conformationally and proteolytically stabilized with all-hydrocarbon staples,

283 Here we describe a novel FPR2 agonist, the proteolytically stable alpha-peptide/beta-peptoid hybrid

284 he study highlights the discovery of a novel proteolytically stable cyclic peptide that can be used f

285 dified to provide antibacterially active and proteolytically stable derivatives.

286 This type of proteolytically stable FPR2-specific peptidomimetics may

287 In our continued effort to design a proteolytically stable ligand with specific receptor bin

288 -dimensional structure of a native HCT and a proteolytically stable lysine mutant enabled the identif

289 Proteolytically stable peptide architectures are require

290 alpha- and beta(3)-residues have emerged as proteolytically stable structural mimics of alpha-helice

291 laying a central role in the assembly of the proteolytically stable trimeric complex and its correct

292 n1) isomerase resulted in potent, selective, proteolytically stable, and biologically active inhibito

293 Yos9, consisting of residues 22-421, that is proteolytically stable, highly structured, and able to f

294 This effector proteolytically targeted Rab32, which controls traffic t

295 itreous IGFBP-3 revealed that the protein is proteolytically truncated at the C terminus.

296 ming motif and a cryptic CendR motif that is proteolytically unmasked in tumor tissue.

297 We report that SlrR is proteolytically unstable and present evidence that self-

298 region attached to a DNA binding domain, are proteolytically unstable in yeast, and it has been sugge

299 diseases, including hypertension in which a proteolytically unstable RGS2 mutant has been reported.

300 ssical activators work most efficiently when proteolytically unstable.