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5 Using this approach, we discover that the prototypical activators Gal4 and VP16 target the Snf1 (A
7 MD, the pathophysiological importance of the prototypical acute-phase reactant in the etiology of the
9 wever, this is probably not the case for the prototypical agent (11)C-PK11195 ((11)C-labeled N-butan-
14 sment of the biodistribution in rodents of a prototypical Alexa647-labeled trivalent conjugate showed
15 ex of RIIbeta and Cbeta, with or without the prototypical anchoring protein AKAP18alpha, revealed tha
18 y exist within the technologically important prototypical and pervasive insulator, polyethylene (PE),
19 Herein, a systematic mechanistic study of a prototypical anion-binding reaction, the thiourea-cataly
20 Thermus thermophilus and compare this to the prototypical antiporter NhaA from Escherichia coli and t
24 r the first time, theoretically predict four prototypical aqueous-drug diffusion coefficients in five
25 accharide-stimulated monocytes was used as a prototypical assay of HDL's immunomodulatory capacity.
27 ce energy transfer spectroscopy to study the prototypical ATP-binding cassette exporter MsbA reconsti
37 osphodiesterases (2',5'-PDEs) encoded by the prototypical Betacoronavirus, mouse hepatitis virus (MHV
39 sistence of human cytomegalovirus (CMV), the prototypical betaherpesvirus, is particularly complex in
43 ith concentrations of denatonium benzoate, a prototypical bitter compound, and the limit of detection
44 ing 34 mouse bitter taste receptors with 128 prototypical bitter substances in a heterologous express
47 KMC) model that describes the formation of a prototypical boronate-ester linked 2D COF known as COF-5
48 cally, disambiguation relies on knowledge of prototypical bouncing events that contain characteristic
50 demonstrate that mammalian PKDs 1-3 and the prototypical Caenorhabditis elegans PKD, DKF-2A, are exc
54 generation measurements of the SCN(-) ion, a prototypical chaotrope, determined a free energy of adso
57 the appropriate normal forms, an "intrinsic" prototypical characterization of the types of dynamical
58 ic injury is associated with upregulation of prototypical chemoattractant cytokines mediating retenti
61 The angiotensin-II type 1 (AT1) receptor, a prototypical class A G protein-coupled receptor, can act
63 ss of house dust mite allergen extracts as a prototypical complex extract that may be standardized by
68 e, we examine the dissociation dynamics of a prototypical Criegee intermediate by characterizing the
72 effector T cells identified as secretors of prototypical cytokines IFNgamma, IL4, IL9, and IL-17A re
73 ow that in response to lysosomal damage, the prototypical cytosolic secretory autophagy cargo IL-1bet
75 zed diabodies (DA) as surrogate ligands in a prototypical dimeric receptor-ligand system, the cytokin
76 (CS+) and safe (CS-) stimulus reverse, in a prototypical disorder of inflexible behavior influenced
83 ancer, in vertebrates), is recognized as the prototypical effector of chemoattraction, with roles in
88 cated in a number of disease states, and the prototypical example is Clostridium difficile infection
91 Vinylidene-acetylene isomerization is the prototypical example of a 1,2-hydrogen shift, one of the
100 myoglobin and beta-lactoglobulin, which are prototypical examples of helical and beta-sheet proteins
104 -induced spin-state trapping dynamics of the prototypical [Fe(bpy)3](2+) compound by time-resolved X-
109 The visual photo-transduction cascade is a prototypical G protein-coupled receptor (GPCR) signaling
111 uman beta2-adrenergic receptor (beta2AR) - a prototypical G protein-coupled receptor - is modulated b
112 sed this issue by studying the mobility of a prototypical G protein-coupled receptor, the neurokinin-
114 The visual photoreceptor rhodopsin is a prototypical G-protein-coupled receptor (GPCR) that stab
115 ity at the micro opioid receptor (microR), a prototypical G-protein-coupled receptor that is a physio
116 riophage lambda-terminase, which serves as a prototypical genome packaging motor, is composed of one
117 med (MRJ) particle packings can be viewed as prototypical glasses in that they are maximally disorder
121 cling of the beta2-adrenoceptor (beta2AR), a prototypical GPCR, and then investigate the effects of V
127 The appearance of nematic behaviour in a prototypical heavy-fermion superconductor highlights the
129 cts and acini of the human mammary gland are prototypical heterogeneous and dynamic tissues comprisin
133 mparison to the corresponding values for the prototypical HKUST-1 (tbo-MOF-1), and are 42% and 20% hi
135 amics simulations to probe the dynamics of a prototypical hydrogen-bonded alcohol, liquid methanol.
136 ient to transform ammonia monohydrate from a prototypical hydrogen-bonded crystal into a form where t
137 D) simulations of the unbinding of a popular prototypical hydrophobic cavity-ligand system using a me
140 ispersion that the D2 domain of p27(Kip1), a prototypical IDP, samples multiple discrete, rapidly exc
141 report the process of glutamate binding to a prototypical iGluR, GluA2, in atomistic detail using unb
143 signature in natural killer (NK) cells, the prototypical ILC subset, and provide a systems-based mol
145 ter resistance to water penetration than the prototypical inorganic-organic lead-containing halide pe
146 pproach achieves high accuracy in describing prototypical interacting spins models in one and two dim
147 organismal responses to pathogens, eliciting prototypical "interferon signature genes" that encode an
150 In the case of the Src tyrosine kinase, a prototypical kinase due to its role in cancer and its hi
151 3 (BT-BZT) polycrystalline ferroelectrics, a prototypical lead-free piezoelectric with an ambiguous s
153 port machinery through the activity of Rev's prototypical leucine-rich nuclear export signal (NES).
154 oded by CYP1A1, in response to the exogenous prototypical ligand 2,3,7,8-tetrachlorodibenzo-p-dioxin
155 sing NiCo2O4 as the p-TCO and n-type Si as a prototypical light absorber, a rectifying heterojunction
156 ate dynamics and structural evolution of the prototypical light-driven rotary motor are followed on t
157 d model by investigating the activity of two prototypical linear cationic peptides: magainin 2 amide
159 tered state ((5)MC) as has been observed for prototypical low-spin Fe(II) polypyridine complexes such
161 man scattering study of AMnBi2 (A=Ca, Sr), a prototypical magnetic Dirac system comprising alternatin
162 ent a recessive mouse missense allele of the prototypical mammalian KDEL receptor, KDEL ER protein re
163 Our results encourage further study of this prototypical material and may open a window into investi
164 ements were performed in vacuum gaps between prototypical materials (SiO2-SiO2, Au-Au, SiO2-Au and Au
166 high-mobility group box 1 protein (HMGB1), a prototypical mediator of sterile inflammation, to be a m
168 plant Mitragyna speciosa, represented by the prototypical member mitragynine, are an unusual class of
170 ntiation, emerging data show that Bach2 is a prototypical member of a novel class of transcription fa
172 y, we have identified a crucial role for the prototypical member of the family HNF1A in adult bone ma
174 porter (POT) YdgR from Escherichia coli is a prototypical member of the POT family, functioning in pr
182 se questions, revealing that the carriers of prototypical metal oxides undergo a transition from a po
183 tribute the 600% increase in creep life in a prototypical Mg-rare earth (RE)-Zn alloy to multiple mec
185 ime scale of minutes to hours in response to prototypical mitochondrial stressors (antimycin-A, xanth
188 chiral guest adsorption, demonstrated on the prototypical MOF-5, may revolutionize the production of
189 rt structural and functional analyses of the prototypical molecular bridge linking postsynaptic iGluR
190 ing dynamics of protein L in presence of the prototypical molecular chaperone trigger factor over the
191 his platform, we studied gold junctions with prototypical molecules (Au-biphenyl-4,4'-dithiol-Au, Au-
192 mental mechanistic free-energy profile for a prototypical Morita Baylis-Hillman reaction in methanol.
193 identify driver genes using human tumors or prototypical mouse models, many of which involve loss of
195 nravel this conundrum by heterostructuring a prototypical multi-ordered complex oxide NdNiO3 in ultra
196 analysis of mixed gas hydrate nucleation, a prototypical multicomponent crystallization process.
197 receptor on the surface of T cells that is a prototypical multisite substrate as it contains 20 sites
199 halose to a mouse model of Batten disease, a prototypical neurodegenerative disease presenting with i
206 k, we report magnetic effects in graphene, a prototypical non-magnetic two-dimensional semi-metal, in
207 ound state substrate-bound structure for the prototypical nonadiabatic tunneling system, soybean lipo
209 l patters characterize the dynamic signature prototypical of individual emotion processing, and seemi
211 TMD-head domain relationship by exchanging a prototypical "old" TMD (1933) with a "recent" (2009), mo
212 to represent cognitive domains, and though a prototypical one, we nevertheless urge caution in genera
217 he genome of parainfluenza virus 5 (PIV5), a prototypical paramyxovirus, encodes a V protein that inh
220 ing a patient's profile with the memories of prototypical patients built through previous repeat clin
221 er, although nearly all controls exhibited a prototypical pattern of spatial bias in their judgments,
222 emotion category is associated with unique, prototypical patterns of activity across multiple brain
223 st cancers into integrative clusters reveals prototypical patterns of single-nucleotide variants and
224 we use molecular dynamics simulations of the prototypical Pb(Mg1/3,Nb2/3)O3-PbTiO3 relaxor material t
225 l protein crystallographic structures of the prototypical PC family member furin in different functio
227 terization of a dimeric Pd(I) species in two prototypical Pd-catalyzed aerobic oxidation reactions: a
228 how a 100{011} edge dislocation in SrTiO3, a prototypical perovskite oxide, impacts the local defect
229 lectron-doping-induced phase transition of a prototypical perovskite SmNiO3 induces a large and non-v
233 central vacuole is one of the hallmarks of a prototypical plant cell, and the multiple functions of t
235 2 capture from air have often focused on the prototypical poly(ethylenimine) (PEI) as the aminopolyme
236 ic analysis of the blocking mechanism of the prototypical polyamine toxin NMDAR ion channel blocker a
237 orption-here we show that post exposure of a prototypical porous metal-organic framework to ethylened
238 se are characterized by fibrosis whereby the prototypical prosclerotic growth factor, transforming gr
239 demonstrated by tracking the activity of two prototypical proteases, trypsin and chymotrypsin, as the
240 cell responses, and cross- presented soluble prototypical protein to antigen-specific CD8+ T cells.
241 Lysergic acid diethylamide (LSD) is the prototypical psychedelic drug, but its effects on the hu
243 aling processes, and experimentally, using a prototypical quantum annealing processor, the ability of
244 tatively measure the binding affinity of the prototypical RBP Vts1 for every transcript in the Saccha
245 o the reaction of H with toluene, which is a prototypical reaction in the combustion chemistry of aro
246 tion of fluoride onto these Lewis acids as a prototypical reaction with a nucleophile yielded a libra
247 tudy, we investigated the effects of H2O2, a prototypical reactive oxygen species that is also presen
248 ative mapping from empirical observations to prototypical realizations of the underlying dynamics.
250 epidermal growth factor receptor (EGFR) is a prototypical receptor tyrosine kinase involved in cell g
252 rt the generation of bias "fingerprints" for prototypical ribose containing A3AR agonists and rigidif
253 roper transport and local translation from a prototypical RNA granule substrate and for mGluR-LTD in
257 onsidering heterogeneous water freezing as a prototypical scenario of practical relevance, we find th
259 From the study of proteorhodopsin (PR), a prototypical seven-transmembrane light-driven bacterial
260 lation of Phospholipase Cgamma (PLCgamma), a prototypical SH2 containing substrate, by FGF receptors
263 crystal structure of elemental lithium, the prototypical simple metal, is a several-decades-old prob
267 that doping electrons at the surface of the prototypical strong spin-orbit TMD WSe2, akin to applyin
272 Towards this goal, we have synthesized a prototypical superlattice composed of a correlated metal
276 lar, we imposed geometric frustration upon a prototypical system, CaF2, by ball milling it with BaF2,
279 sed peptide, WE14, is a weak agonist for the prototypical T cell, BDC-2.5, and other ChgA-specific T-
283 imetal and topological insulator states in a prototypical three-dimensional (3D) Dirac material, Na3B
284 hexagonal molybdenum ditelluride (MoTe2), a prototypical transition metal dichalcogenide (TMDC) semi
287 widely conserved signaling node comprising a prototypical transmembrane receptor for c-di-GMP, LapD,
288 uman NKT cells that differ markedly from the prototypical TRAV10-TRAJ18-TRBV25-1(+) type I NKT cell r
289 ERT to map the binding site of imipramine, a prototypical tricyclic antidepressant, and vortioxetine,
293 er virulence effectors into host cells via a prototypical type III secretion system to promote pathog
299 sion peptide, and validate the method on two prototypical voltage-dependent proteins, the Kv1.2 K(+)
300 We produced VSV pseudotypes containing the prototypical X-31 (H3) HA, either alone or with strain-m
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