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1 and the biological substrate of human mental prowess".
2 in a phase III randomized controlled trial (PROWESS).
3 r sepsis in a recent phase 3 clinical trial (PROWESS).
4 unique and remarkable scope of its catalytic prowess.
5 in clinical practice differed from those in PROWESS.
6 ve site plays a major role in this enzymatic prowess.
7 represent oncogenic signaling and metastatic prowess.
8 y subjects' knowledge than by their physical prowess.
9 respectively, which may determine metastatic prowess.
10 reduction was much the same as was noted in PROWESS (0.851, 0.740-0.979), but smaller than that of p
12 4 adult patients with severe sepsis from the PROWESS and ENHANCE (a single-arm, open-label study of d
14 how enzymes obtain their fantastic catalytic prowess, and has served as a guiding principle in drug d
17 farming to population growth and to military prowess, both promoting the spread of farming as a livel
18 -mesenchymal transition (EMT) and metastatic prowess, but the underlying mechanisms are incompletely
19 hil cell line, and reduces their chemotactic prowess by causing them to pursue abnormally circuitous
20 ical practice patients compared with 2.2% of PROWESS DrotAA-treated patients with Acute Physiology an
21 tingly, old animals that maintain locomotory prowess exhibit less synaptic decline than same-age decr
26 heir bodies; the basis for this regenerative prowess is an experimentally accessible stem cell popula
27 eased proliferation and diminished migratory prowess, largely resulting from decreased nitric oxide (
32 unction can greatly expand the computational prowess of central axons to allow for precise coordinati
35 taC/C ratios tested, the average chemotactic prowess of individual cells (indicated by the distance a
37 g of the Asn-105 that lends to the catalytic prowess of the enzyme since the organization of the subs
38 1, and 222 were utilized, and the inhibitory prowess of the heteroarotinoids was referenced to that o
39 en), was examined in a large clinical trial (PROWESS) of severe sepsis and a mouse endotoxemia model.
40 psis enrolled and treated with study drug in PROWESS, of whom 1,220 were alive at 28 days (the end of
41 was higher than the 3.5% (2.5-5.0) noted in PROWESS (p=0.003), but similar to that reported in PROWE
43 as 42%, compared with 37% for DrotAA-treated PROWESS patients with Acute Physiology and Chronic Healt
46 rum, we used stepwise logistic regression on PROWESS placebo patients to generate a predicted risk of
47 tor V Leiden survival benefit in the initial PROWESS population, and in mice, suggests that the as-ye
49 valuation of Severe Sepsis and septic Shock [PROWESS SHOCK]) failed to replicate the favorable result
53 d placebo in patients with Severe Sepsis and PROWESS-SHOCK, the average age of patients living at hom
56 ding physicians, selected for their teaching prowess, supervised the teams throughout the workday and
58 the diminution of integrative physiological prowess that occurs solely as a result of ageing, unaffe
60 along with clinical trial databases from the PROWESS trial and a phase I human endotoxin trial evalua
62 These data suggest that strict adherence to PROWESS trial exclusion criteria would further limit ser
63 ning curve appeared to be present within the PROWESS trial such that the ability to demonstrate effic
64 educing mortality in severe sepsis patients (PROWESS trial) that gave impetus to new directions for b
67 ein C Worldwide Evaluation in Severe Sepsis (PROWESS) trial, but controversies about its effectivenes
68 pared with chorismate mutase whose catalytic prowess, when compared with water, originates predominan
69 that quantify career longevity, success, and prowess, which together contribute to the overall succes
70 0.979), but smaller than that of patients in PROWESS with high disease severity (0.708, 0.590-0.849).
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