ライフサイエンスコーパス: proximal tubule

1 basolateral exit pathway for creatine in the proximal tubule.

2 DDAH1 is expressed predominately within the proximal tubule.

3 CAII colocalizes with AQP1 in the renal proximal tubule.

4 returned to the systemic circulation by the proximal tubule.

5 E3-mediated NaHCO3 reabsorption in the renal proximal tubule.

6 orters and NHE3 interact functionally in the proximal tubule.

7 directly regulate sodium reabsorption in the proximal tubule.

8 ed in mice lacking Met receptor in the renal proximal tubule.

9 ent recombination was absolutely specific to proximal tubule.

10 es with SGLT2 but not SGLT1 in the rat renal proximal tubule.

11 s, which is expressed only in differentiated proximal tubule.

12 glucose uptake on NHE3 activity in the renal proximal tubule.

13 or receptors for protein reabsorption in the proximal tubule.

14 transcellular process that occurs along the proximal tubule.

15 ified model for both podocytes and the renal proximal tubule.

16 se regulate sodium reabsorption in the renal proximal tubule.

17 urinary protein excretion via effects in the proximal tubule.

18 th structure and function of the human renal proximal tubule.

19 tal tubules and collecting ducts, but not of proximal tubule.

20 receptors, which are highly expressed in the proximal tubule.

21 f impaired cystine reabsorption in the renal proximal tubule.

22 ce of GLUT2 in glucose absorption across the proximal tubule.

23 rentiate into any nephron segments, not just proximal tubules.

24 compensatory increase in prourine uptake in proximal tubules.

25 d noted ectopic expression in P7 non-dilated proximal tubules.

26 well as clustering of macrophages around S1 proximal tubules.

27 espectively, which in pigs, localized to the proximal tubules.

28 dicator (GCaMP2) predominantly in the kidney proximal tubules.

29 -Dapa binding to the apical surface of early proximal tubules.

30 ed the size of the kidney, in particular the proximal tubules.

31 icially placed, ectopic, well-differentiated proximal tubules.

32 a membrane-bound metalloproteinase in renal proximal tubules.

33 ephron derivatives, but disappears in mature proximal tubules.

34 however, it disappeared in mature NP-derived proximal tubules.

35 that it resides on basolateral membranes of proximal tubules.

36 but not in IL-11 receptor-deficient or renal proximal tubule A1 adenosine receptor-deficient mice.

37 own as TIM-1) is markedly upregulated in the proximal tubule after injury and is maladaptive when chr

38 ture nephron structures and dedifferentiated proximal tubules after acute kidney injury.

39 We studied proximal tubules after ischemia-reperfusion injury (IRI)

40 Adv-COPI protected distal and proximal tubules against hypoxia/reoxygenation-enhanced

41 e changes functionally uncouple cells of the proximal tubule ahead of any overt loss in epithelial ce

42 In the kidney, the proximal tubule allows both transcellular and paracellul

43 lipiduria enhances lipotoxin delivery to the proximal tubule and accumulation of LC-CoAs contributes

44 n is most abundantly expressed in the kidney proximal tubule and collecting duct epithelia, where it

45 ated roles for sim1a in zebrafish pronephric proximal tubule and CS patterning, and are consistent wi

46 ) intake increased Na(+) reabsorption in the proximal tubule and decreased it in more distal kidney t

47 pha-ketoglutarate (alphaKG) transport in the proximal tubule and Henle's loop from reabsorption (acid

48 In the proximal tubule and in other tissues, MAP17 is known to

49 ium absorption is mainly paracellular in the proximal tubule and in the thick ascending limb of the l

50 ) intake decreased Na(+) reabsorption in the proximal tubule and increased it in distal segments with

51 ed that pronephric nephrons require osr1 for proximal tubule and podocyte development.

52 pivotal role in the early dysfunction of the proximal tubule and the subsequent renal repair.

53 own produced cysts predominantly arising in proximal tubules and descending limbs of loops of Henle.

54 eys of newborn mutant mice exhibited dilated proximal tubules and immature glomeruli, and the renal p

55 orm a heterogeneous population that includes proximal tubules and other types of cells.

56 in fewer numbers of autophagic cells in the proximal tubules and reduced ratio of the autophagy-rela

57 t, Notch signaling promotes the formation of proximal tubules and represses the formation of distal t

58 at Notch signaling promotes the formation of proximal tubules and represses the formation of distal t

59 uced apoptosis in microperfused Slc27a2(-/-) proximal tubules and Slc27a2(-/-) or FATP2 shRNA-treated

60 at epithelial cell plasma membranes in renal proximal tubules and thin descending limb of Henle.

61 yo-inositol oxygenase (MIOX) is expressed in proximal tubules and up-regulated in the diabetic state.

62 tosis, were deleted specifically from kidney proximal tubules and used this model to examine renal ap

63 production (e.g. ectopic Ccl2 in non-dilated proximal tubules), and augmented hedgehog signaling, fea

64 o SGLT2 in the apical membranes of the early proximal tubule, and is subsequently reabsorbed into blo

65 n at several locations, including podocytes, proximal tubule, and the vasculature.

66 lized with the endocytic receptor megalin in proximal tubules, and compared with wild-type mice, mega

67 stering of macrophages around S1 segments of proximal tubules, and full renal protection required bot

68 al tubulointerstitial disease resulting from proximal tubule antigen-specific antibodies and immune c

69 e of tubular atrophy, which is the result of proximal tubule apoptosis.

70 Furthermore, proximal tubules are predisposed to become cystic after

71 In the kidney, proximal tubules are very important for the reabsorption

72 icient to cause neoplastic transformation of proximal tubules, arguing against the idea that HIF2alph

73 dent phosphoinositide 3-kinase activation in proximal tubules as a critical determinant of initial tu

74 own that double knockout of Bax and Bak from proximal tubules attenuated renal tubular cell apoptosis

75 at luminal surface expression of AQP1 in the proximal tubule brush border membrane is regulated in re

76 onstitutively enhanced AQP1 abundance in the proximal tubule brush border membrane.

77 tubular Na(+) reabsorption increased in the proximal tubule but decreased in the distal nephron beca

78 tubular Na(+) reabsorption decreased in the proximal tubule but increased in distal segments with lo

79 rters detected in the apical membrane of the proximal tubule but not detected in other organs likely

80 t Eci3 is not only expressed in cells of the proximal tubule, but also in a subset of cells in the tu

81 rminal Sepp1 forms are taken up in the renal proximal tubule by another receptor, megalin.

82 indicates that hepcidin is reaborbed in the proximal tubules by megalin dependent endocytosis.

83 nd subsequent reabsorption by the downstream proximal tubule, causing lipoapoptosis.

84 ed a critical role of adenosine generated by proximal tubule CD73 expression in abrogating IRI.

85 2 (GLUT2) during diabetes may lead to renal proximal tubule cell (RPTC) injury, inflammation, and in

86 ion initiates its translocation to the renal proximal tubule cell apical membrane and the internaliza

87 AT2R activation increased renal proximal tubule cell apical membrane AT2R protein (P<0.0

88 ectively, these findings indicate that renal proximal tubule cell CB1R contributes to the pathogenesi

89 ogous expression of KIM-1 in an immortalized proximal tubule cell line triggered MCP-1 secretion and

90 In MCT cells, a mouse renal proximal tubule cell line, ATP depletion by antimycin A

91 In a renal proximal tubule cell line, either pharmacologic or genet

92 atin-induced apoptosis in the DR3(+/+) mouse proximal tubule cell line, TKPTS.

93 ules and Slc27a2(-/-) or FATP2 shRNA-treated proximal tubule cell lines compared with wild-type or sc

94 educed amounts of megalin and cubilin at the proximal tubule cell surface in Rab38 knockout versus co

95 The Na+/H+ exchanger NHE1 regulates proximal tubule cell survival through interaction with p

96 al, and functional similarities to the renal proximal tubule cell.

97 ed NHE3 expression (-50+/-9%) in human renal proximal tubule cells (hRPTCs).

98 daily from the glomerular filtrate by kidney proximal tubule cells (PT), requiring ferrireductase act

99 ct of catalase (Cat) overexpression in renal proximal tubule cells (RPTCs) on nuclear factor erythroi

100 Human renal proximal tubule cells (RPTECs) were used to characterize

101 undant levels of APOL1 mRNA were observed in proximal tubule cells and glomerular endothelial cells,

102 nificance of this interaction in human renal proximal tubule cells and HEK293 cells stably expressing

103 closporine A (CsA) treated and control human proximal tubule cells and identified mRNAs undergoing ac

104 characterizes the development of atrophy in proximal tubule cells and may contribute to the renal pa

105 ke of fluorescently labeled NEFA in cultured proximal tubule cells and microperfused rat proximal tub

106 rs is antagonized by adenosine reuptake into proximal tubule cells by equilibrative nucleotide transp

107 During recovery by regeneration after AKI, proximal tubule cells can fail to redifferentiate, under

108 to identify the conditions under which adult proximal tubule cells could be directly transcriptionall

109 that specific deletion of CB1R in the renal proximal tubule cells did not protect the mice from obes

110 e expression profiles in nondiseased primary proximal tubule cells from black patients revealed that

111 Compared with primary renal proximal tubule cells isolated from KIM-1Deltamucin mice

112 Differentiated proximal tubule cells showed upregulation of specific ge

113 on of gallein on normal rat kidney (NRK-52E) proximal tubule cells significantly reduced (P < 0.05) S

114 In rat proximal tubule cells that express endogenous AT1R and D

115 conditioned media from high glucose-treated proximal tubule cells to induce transmigration of mononu

116 In vitro, exposure of proximal tubule cells to the inflammatory cytokines IFN-

117 2 receptors and Galphaq proteins of cultured proximal tubule cells to transactivate latent TGF-beta i

118 Immediately after the onset of albuminuria, proximal tubule cells underwent a transient burst of pro

119 Treatment of cultured proximal tubule cells with mouse recombinant sclerostin

120 on the apical brush-border membrane of 786-O proximal tubule cells within the OOC surface, and the re

121 reach the primary filtrate, are captured by proximal tubule cells, and are endocytosed.

122 Moreover, in pig kidney proximal tubule cells, cisplatin-induced mitochondrial t

123 Primary cilia were elongated in proximal tubule cells, collecting duct cells and parieta

124 In AQP1-transfected, cultured proximal tubule cells, fluid shear stress or the additio

125 t age-associated lysosomal defects in kidney proximal tubule cells, in the absence of frank CNS patho

126 e receptor-2 promoter-driven Cre-transfected proximal tubule cells, suggesting that knockdown of stan

127 f mitochondrial respiration in human primary proximal tubule cells.

128 gial cells, glomerular endothelial cells, or proximal tubule cells.

129 h conditioned media from serum-starved mouse proximal tubule cells.

130 n regulating paracellular transport of renal proximal tubule cells.

131 d pathophysiologic albumin concentrations in proximal tubule cells.

132 antagonism decreased fibronectin in cultured proximal tubule cells.

133 substrate accumulation in cystinotic kidney proximal tubule cells.

134 d fusion with the basolateral membrane in S1 proximal tubule cells.

135 ll growth inhibition and cell death in renal proximal tubule cells.

136 mitochondrial morphology and respiration in proximal tubule cells.

137 uting the cation-reabsorptive pathway in the proximal tubule; claudin-14, -16, and -19 as forming a c

138 In the proximal tubule, claudins have a role in the bulk reabso

139 ephrogenesis and early kidney growth, single proximal tubule clones expanded, suggesting that differe

140 spicuous in the tubular basement membrane of proximal tubules, corresponding to deposits observed by

141 tein efflux-transporters (MRPs) in the renal proximal tubule could enhance this unwanted effect.

142 Results obtained from proximal tubule cultures derived from Nur77-deficient mi

143 nce mainly attributed to a greater number of proximal tubule cysts.

144 s with ABBA disease who had a combination of proximal tubule damage, IgG-positive immune deposits in

145 es the actions of TGF-beta, leading to renal proximal tubule dedifferentiation, an important event in

146 Renalase, an amine oxidase secreted by the proximal tubule, degrades circulating catecholamines and

147 renal dopamine production, we used mice with proximal tubule deletion of aromatic amino acid decarbox

148 Lastly, proximal tubule deletion of DRP1 after ischemia-reperfus

149 The proximal tubules demonstrate a corresponding up-regulati

150 a renal cystic model, ectopic p-Creb stained proximal tubule-derived cystic segments that lost the di

151 In proximal tubule-derived, PC1-knock-out cells, adenylyl c

152 hat Par1a/b has a key role in glomerular and proximal tubule development, likely via modulation of No

153 Adult CLIC4-null proximal tubules display aberrant dilation.

154 with tamoxifen-induced Wnt1 expression from proximal tubules displayed interstitial myofibroblast ac

155 w-level transfection of the collecting duct, proximal tubule, distal tubule, interstitial cells, and

156 ells, induced expression of several of these proximal tubule DMEs, as well as epithelial markers and

157 Compared with control proximal tubules, DN, FSGS, IgAN, and MPGN proximal tubu

158 d to ectopic expansion of podocytes into the proximal tubule domain.

159 lial cells, which were inhibited in diabetic proximal tubule EGFR-knockout mice (EGFR(ptKO)) or admin

160 ceptor function and therefore is a marker of proximal tubule endocytic activity.

161 n are cooperating receptors essential to the proximal tubule endocytic uptake of proteins from the gl

162 impairment of which has a dramatic effect on proximal tubule endocytosis.

163 Injury to labeled proximal tubule epithelia induced expression of CD24, CD

164 NBCe1 protein in the basolateral membrane of proximal-tubule epithelia is the most probable cause of

165 Treatment of human proximal tubule epithelial (HK-2) cells with a selective

166 ted using lipopolysaccharide-activated human proximal tubule epithelial (HK-2) cells.

167 ing BKPyV intracellular trafficking in renal proximal tubule epithelial (RPTE) cells, a natural host

168 and clonal behavior of fully differentiated proximal tubule epithelial cells after injury.

169 ssion mediated by Notch-2 signaling in renal proximal tubule epithelial cells aid in the functional a

170 Kidney FATP2 localized exclusively to proximal tubule epithelial cells along the apical but no

171 ted tubular architecture is circumscribed by proximal tubule epithelial cells and actively perfused t

172 Renal proximal tubule epithelial cells express high levels of

173 TRPM2 was localized mainly in kidney proximal tubule epithelial cells, and studies in chimeri

174 dneys, CLIC4 is specifically enriched in the proximal tubule epithelial cells, in which CLIC4 is impo

175 ion were upregulated in diabetic mouse renal proximal tubule epithelial cells, which were inhibited i

176 roperties of terminally differentiated renal proximal tubule epithelial cells.

177 The proximal tubule epithelium relies on mitochondrial funct

178 g EGF-like growth factor (hHB-EGF), in renal proximal tubule epithelium.

179 Mice with CD73 deletion in proximal tubules exhibited exacerbated IRI, comparable w

180 d displays nuclear expression in the hypoxic proximal tubules exhibiting high levels of autophagy.

181 albumin at concentrations that mimic apical proximal tubule exposure during glomerular injury reveal

182 RNA expression analyses revealed that kidney proximal tubules express transmembrane fatty acid transp

183 l perfusion rates in isolated, microperfused proximal tubules for 15 minutes.

184 form the distal tubule and to restrict both proximal tubule formation and MCC fate choice.

185 ture microdissection to obtain glomeruli and proximal tubules from 98 human needle kidney biopsy spec

186 tol administration protected the human donor proximal tubules from normothermic-induced cell swelling

187 role of FtH and reveal the critical role of proximal tubule FtH in iron trafficking in AKI.

188 RL) and share the feature of impaired kidney proximal tubule function.

189 l proximal tubules, DN, FSGS, IgAN, and MPGN proximal tubules had differential expression of 13, 14,

190 Whether kidney proximal tubule harbors a scattered population of epithe

191 o antibodies to brush border antigens of the proximal tubule has been demonstrated experimentally and

192 e data suggest that glomerular podocytes and proximal tubules have different requirements for PIKfyve

193 In cultured human proximal tubule (HK-2) cells, the S1P(2)R antagonist sel

194 ced cytotoxicity progression in human kidney proximal tubule (HK-2) cells.

195 me/nephron progenitor phenotype in the adult proximal tubule (HK2) cell line.

196 cell line for human epithelial cells of the proximal tubule (HK2) to demonstrate that Ketamine evoke

197 hese results suggest that induction of renal proximal tubule IL-11 is a critical intermediary in A1 a

198 s support a role for insulin receptor in the proximal tubule in the modulation of systemic glucose le

199 tic receptor, is markedly upregulated in the proximal tubule in various forms of acute and chronic ki

200 oprinting method for creating 3D human renal proximal tubules in vitro that are fully embedded within

201 Similar results were observed in cultured proximal tubules, in which labeled clones proliferated a

202 sclerosis complex protein 1 (Tsc1) in renal proximal tubules induced strikingly enlarged kidneys, wi

203 of epidermal growth factor receptor in renal proximal tubule induces tubulointerstitial fibrosis.

204 c knockdown of stanniocalcin-1 led to severe proximal tubule injury characterized by vacuolization, d

205 ys after cisplatin treatment, more extensive proximal tubule injury was observed in Mrp2-null mice co

206 expression of well-characterized markers of proximal tubule injury.

207 Transepithelial water flow across the renal proximal tubule is mediated predominantly by aquaporin-1

208 investigate whether Wnt ligand derived from proximal tubule is sufficient for renal fibrogenesis, we

209 ium glucose cotransporter SGLT2 in the early proximal tubule is the major pathway for renal glucose r

210 but the role of the insulin receptor in the proximal tubule is unknown.

211 This damage occurs primarily by killing of proximal tubule kidney cells and mechanosensory hair cel

212 nd enhanced apoptosis, whereas inhibition of proximal tubule LC-CoA generation preserved NHE1 activit

213 drug cisplatin is actively transported into proximal tubules, leading to acute renal injury.

214 og (Shh) in subsets of non-dilated P7 mutant proximal tubules (likely driving the stromal Gli express

215 pattern in which genes of the glomerular and proximal tubule lineages were either unchanged or upregu

216 atty acids, LC-CoAs, and caspase-2-dependent proximal tubule lipoapoptosis.

217 In addition, in cultured proximal tubule LLC-PK1 cells, knockdown of Rab38 mRNA s

218 AI1 protein was detected within cytoplasm of proximal tubules localized, for some of them, near foci

219 meaningful increases in sodium exit from the proximal tubule/loop of Henle.

220 Because glomerular injury permits proximal tubule luminal exposure and reabsorption of fat

221 Similarly, proximal tubule megalin expression was reduced by diabet

222 erfusion-induced AKI, meprin A was shed from proximal tubule membranes, as evident from its redistrib

223 iew that OAT1 plays a greater role in kidney proximal tubule metabolism and OAT3 appears relatively m

224 suggesting that CsA+SRL negatively impacted proximal tubule metabolism.

225 genous PTH with redistribution of Npt2a from proximal tubule microvilli to intracellular compartments

226 nephritis and ultrastructural changes in the proximal tubule mitochondria associated with aberrant tu

227 In conclusion, AC6 in the proximal tubule modulates cAMP formation, Npt2a traffick

228 ombined knockdown of prkciota/zeta disrupted proximal tubule morphogenesis and podocyte migration due

229 esponses; greater reductions in abundance of proximal tubule Na(+)/H(+) exchanger 3, Na(+)/Pi co-tran

230 nism of regulation of ouabain-mediated renal proximal tubule Na/K-ATPase signal transduction and subs

231 This effect relies on increased proximal tubule NaPi-IIa expression secondary to decreas

232 AT2R activation holds promise as a renal proximal tubule natriuretic/diuretic target for the trea

233 In the kidney proximal tubule, NBCe1-A plays a critical role in absorb

234 We conclude that FATP2 is a major apical proximal tubule NEFA transporter that regulates lipoapop

235 In STN kidneys, the S3 segment of the proximal tubule, normally injured after ischemia, consti

236 ex, indicating the protective effects on the proximal tubule occur primarily through modulation of th

237 pared with the proximal tubule of males, the proximal tubule of females had greater phosphorylation o

238 Compared with the proximal tubule of males, the proximal tubule of females

239 (FGF-23) enhance phosphate excretion by the proximal tubule of the kidney by retrieval of the sodium

240 High albumin concentrations in the proximal tubule of the kidney causes tubulointerstitial

241 er that specifically indicates injury to the proximal tubule of the kidney has been identified.

242 trate that deleting the beta1 subunit in the proximal tubule of the kidney results in a major urine-c

243 reticulum stress, was more prominent in the proximal tubules of 15 obese patients compared with 16 n

244 g expression of NUPR1 in the nuclei of renal proximal tubules of injured human kidney allografts, but

245 t Met receptor expression selectively in the proximal tubules of mice (gammaGT-Cre;Met(fl/fl)).

246 30A, and N851A, named as HIF2alphaM3) in the proximal tubules of mice is not sufficient to promote cc

247 ly knocked out the insulin receptor from the proximal tubules of mice.

248 singly mobile in the microvilli of the renal proximal tubule OK cell line.

249 directly alter phosphate uptake in cultured proximal tubule OK cells.

250 These engineered 3D proximal tubules on chip exhibit significantly enhanced

251 otein, glucose, or phosphate handling in the proximal tubule or with the presence of >/=2 of these ma

252 in-dependent and -independent endocytosis in proximal tubules, phenocopying what has been reported fo

253 Furthermore, unlike the osr1-deficient proximal tubule phenotype, which can be rescued by manip

254 s relative phosphate retention via increased proximal tubule phosphate reabsorption.

255 ing cell populations with characteristics of proximal tubules, podocytes and endothelium.

256 of the filtered calcium is reabsorbed in the proximal tubule, primarily by paracellular mechanisms th

257 every facet of life-requires that the renal proximal tubule (PT) adjust its rate of H(+) secretion (

258 Proximal tubule (PT) cells are critical targets of acute

259 fusion injury by directly activating S1P1 on proximal tubule (PT) cells, independent of the canonical

260 accumulate within epithelial cells, causing proximal tubule (PT) dysfunction and renal Fanconi syndr

261 they appear to be dispensable for mammalian proximal tubule (PT) function.

262 Cells lining the proximal tubule (PT) have unique membrane specialization

263 Recent data highlight the role of the proximal tubule (PT) in reabsorbing, processing, and tra

264 ively referred to as DMEs) in the developing proximal tubule (PT) is not well understood.

265 and other small molecules is mediated by the proximal tubule (PT) multiligand receptors megalin and c

266 Cells lining the proximal tubule (PT) of the kidney are highly specialize

267 In the proximal tubule (PT) of the kidney, claudin-2 mediates p

268 nic cation transporters (OCTs) in the kidney proximal tubule (PT) participate in renal excretion of d

269 concept that both glomerular filtration and proximal tubule (PT) reclamation affect urinary albumin

270 In vitro data indicates that the kidney proximal tubule (PT) transporters of uremic toxins and s

271 The renal proximal tubule reabsorbs 90% of the filtered glucose lo

272 he in vivo role of these signaling events in proximal tubule responses to kidney injury has been diff

273 (211)At- 6: also showed uptake in renal proximal tubules resulting in late nephrotoxicity, highl

274 f F0F1-ATPase activity after injury in renal proximal tubules (RPTC).

275 expression of Kim1 and vimentin in scattered proximal tubule segments.

276 blood-brain barrier, hepatocytes, and kidney proximal tubule, serving a protective function for the b

277 s the D1-like receptor from inhibiting renal proximal tubule sodium transport, neutralizing the natri

278 t of fenoldopam and its inhibitory effect on proximal tubule sodium transport.

279 A novel proximal tubule-specific Ddah1 knockout (Ddah1(PT-/-)) m

280 Using genetic murine models, we found that proximal tubule-specific deletion of Drp1 prevented the

281 Proximal tubule-specific deletion of Egfr in Pten(ptKO)

282 Here, we demonstrated that mice harboring a proximal tubule-specific deletion of Pten (Pten(ptKO)) h

283 overy from AKI, we generated mice with renal proximal tubule-specific deletion of survivin (survivin(

284 njury (AKI) and renal iron handling by using proximal tubule-specific FtH-knockout mice (FtH(PT-/-) m

285 centric" paradigm and focus attention on the proximal tubule that by virtue of the high energy requir

286 injected hhep25 and no hepcidin staining in proximal tubules that lack megalin.

287 n the kidney, magnesium is reabsorbed in the proximal tubule, the thick ascending limb of the loop of

288 in each of 14 renal tubule segments from the proximal tubule through the inner medullary collecting d

289 es can affect all tubular segments, from the proximal tubule to the collecting duct.

290 es the signals inducing the proliferation of proximal tubules to acquire their final organ size.

291 vealed the metabolic signatures of S1 and S2 proximal tubules to be distinct and resolvable at the su

292 We sought to identify the apical proximal tubule transporter that mediates NEFA uptake an

293 vo renal targeting of 8-pCPT-2'-O-Me-cAMP to proximal tubules using a kidney-selective drug carrier a

294 tasis by reabsorbing filtered glucose in the proximal tubules via sodium-glucose cotransporters (SGLT

295 endocytic receptor highly expressed in renal proximal tubules, where it mediates uptake of albumin an

296 1393 is specifically expressed in the kidney proximal tubule, which is the site of renal glucose reab

297 ownregulation of the insulin receptor in the proximal tubule, which occurs in insulin-resistant state

298 proximal tubule cells and microperfused rat proximal tubules, with greater uptake from the apical su

299 n injury (IRI) led to dynamic changes in the proximal tubules, with increased numbers of RFP and EGFP

300 enerated a novel mouse strain with inducible proximal tubule Wnt1 secretion.