ライフサイエンスコーパス: proximally

1 six, the weakness was greater distally than proximally.

2 ms was virtually zero distally and very high proximally.

3 h several recognizable elements concentrated proximally.

4 he vein, focal activity seemed to occur more proximally.

5 naldehyde dehydrogenase 2 (Raldh2) expressed proximally.

6 rker D3S3691 distally and by the gene ATP2B2 proximally.

7 lected the arterial occlusion occurring more proximally.

8 tal end that give rise to meiotic cells more proximally.

9 ated in the leading edge and galectin-3 more proximally.

10 val, with a worse outcome as the tumor moves proximally.

11 nd toward a worse outcome as the tumor moves proximally.

12 at is severalfold greater than that observed proximally.

13 polymerizing drugs than the polymer situated proximally.

14 rsal V2a cells have higher synapse densities proximally.

15 fasciculation syndrome more frequently arise proximally.

16 istally and bigeminal and trigeminal rhythms proximally.

17 ast distally and the extraembryonic ectoderm proximally.

18 e of the fin, significant growth also occurs proximally.

19 and accumulate abnormal and degraded oocytes proximally.

20 hile the Bmp4 expression domain was expanded proximally.

21 fined to the 3.3-kb repeats but extends both proximally (42 kb) and distally to include the telomere.

22 ircumferential involvement was more frequent proximally, a similar pattern to native atherosclerosis.

23 receptor antagonists) should be avoided, and proximally acting agents (e.g., acetazolamide and loop d

24 and CSF-1R were coexpressed in RCCs and TECs proximally adjacent to RCCs.

25 Proximally, all V2a neurons have axonal distributions th

26 ACS-1 did not proximally alter EGF receptor or integrin signaling, but

27 d they always contacted relay cell dendrites proximally among retinal terminals (the retinal recipien

28 at the rate of regeneration is more rapid in proximally amputated appendages compared with distal amp

29 enchymal stem cells (mBMSCs) to regenerate a proximally amputated digit tip.

30 The hip capsule inserts proximally and continuously to the acetabular rim perios

31 a 7-cM (4.3-Mb) interval flanked by D19S928 proximally and D19S425 distally.

32 further defined RMD-1 between markers D6S186 proximally and D6S227 distally.

33 Perturbations evoked proximally and distally propagate along the loop, rendez

34 haracterizes complex circuits involving both proximally and distally regulating transcription factors

35 Subsequently it spreads proximally and distally, covering the entire afferent su

36 ters away from the synaptic input site, both proximally and distally, dendritic calcium transients ar

37 and flanked by "wings" W1 and W2 positioned proximally and distally, respectively, to the transcript

38 ial regulatory targets, acting both receptor proximally and distally, that can terminate or amplify t

39 noncancerous lesions are equally distributed proximally and distally.

40 siological TGF-beta signaling gradient (high proximally and low distally) and its functional correlat

41 tine nucleus stimulation restored StartReact proximally and proximal reaction times to loud stimuli c

42 e found that hsh is flanked between D3Mit187 proximally and S100a4 distally.

43 Clusters arise first dorsally and proximally and spread over the entire intestine within 2

44 cleic-acid translocases, may bind substrates proximally and, coupled with ATP hydrolysis, translocate

45 and regulators of the TFIID pathway located proximally, and (5) distinct mobilization of SAGA- versu

46 to have the V600E BRAF mutation, be located proximally, and occur in older individuals (in univariat

47 ucleotide diversity was high distally, lower proximally, and very low nearest the centromere.

48 comprised of a Cu(II)-centered core with two proximally appended tripeptide arms emanating outward.

49 ia phospholipase C activation, PKC acts more proximally as an upstream activator of PKD.

50 key roles in cell-cell communication, acting proximally as well as systemically.

51 scle weakness that was greater distally than proximally, as well as respiratory insufficiency, cardio

52 anxiety and substance use disorders were not proximally associated with suicidality.

53 However, if mouse cells are implanted either proximally at stage 21 or into the limb tip at stage 24,

54 of the extrahepatic bile duct were measured proximally at the porta hepatis, at the middle above the

55 poneurotic fibers and Muller's muscle attach proximally at the superior tarsal border.

56 ecruited from a pool of polymerases that are proximally bound to the replisome and continuously reple

57 ably due to the necessity for interaction of proximally bound transcription factors, while a facilita

58 activator such as E2F or actively represses proximally bound transcription factors.

59 ning a p53 response element which is located proximally (bp -168 to -57) to the transcription start s

60 ese, hIK1-like immunoreactivity was detected proximally but not distally to injury, whereas neurofila

61 ing successive evaginations that "zipper" up proximally, but at their leading edges are free to make

62 ith two nearly orthogonal stems, each capped proximally by a G x G mismatch pair, binding the AMP lig

63 didate region of approximately 20 cM flanked proximally by D15S983 and distally by D15S127 on human c

64 of deletion flanked distally by D1S2713 and proximally by D1S2134, which spans 1.5 cM within 1p32.

65 has been mapped to a region of 1q41 flanked proximally by D1S217 and distally by D1S439.

66 ve FOP gene within a 36-cM interval bordered proximally by D4S1625 and distally by D4S2417.

67 n mouse chromosome 7 in the interval defined proximally by hemoglobin beta (Hbb), D7Mit38, D7Mit2l7,

68 roximately 2.1 Mb recurrent deletion flanked proximally by LCR22-4 and distally by either LCR22-5 or

69 a minimal region of common deletion flanked proximally by marker GSN on 9q33.

70 al ectodermal ridge, both Fgfs and Bmps, and proximally by retinoic acid signaling.

71 1H), T(33H), and T(36H), which extended more proximally, caused male sterility when heterozygous with

72 Conversely, more proximally charged residues of the collagen receptor tha

73 Although proximally continuous with villous cytotrophoblast (CTB)

74 he distal ligand binding properties of these proximally detached Hbs.

75 tern of focal and noncircumferential disease proximally, diffuse and circumferential disease distally

76 There is also a small proximally directed progression of NF-M expression.

77 hers to argue for two overlapping components proximally displaced from the OCJ: an extrinsic crural s

78 a DSB using short dispersed repeats located proximally, distally, or even on separate molecules rela

79 nd expression of marker genes, including the proximally expressed hepatocyte nuclear factor/forkhead

80 ate distinct signaling pathways that diverge proximally following receptor activation but converge di

81 ce open, the gastroesophageal junction moved proximally for the duration of the transient lower esoph

82 Proximally, Foxo3a is regulated by different pathways in

83 segments (ROS) that are continuously formed proximally from connecting cilia (CC) and phagocytized d

84 ring a 1.82-Mb chromosomal segment extending proximally from p.

85 ses a 16-21 nucleotide RNA segment extending proximally from the 3' end of the chain.

86 10 cm distally from the midthigh, and 10 cm proximally from the midthigh).

87 The enlargement extended proximally from the point of nerve transection to a leve

88 murine cardiac conduction system, extending proximally from the sinoatrial node to the distal Purkin

89 Searching for a proximally generated diffusible factor capable of activa

90 The large bundles that are present proximally gradually split into smaller bundles as the a

91 CT2 is the most proximally identified gene on chromosome 16p to date.

92 to include cysteine pairs that are presented proximally if the cage state assembles.

93 Thus, alphaIIbbeta3 interacts proximally, if not directly, with tyrosine kinases in a

94 We see these divergent effects of proximally immobilized cations also in single-molecule m

95 h starts in the rectum and generally extends proximally in a continuous manner through part of, or th

96 he coding sequences in monocots is localized proximally in regions of very low and even negligible re

97 ations affecting a residue (R4) located more proximally in S(4) caused activation of gating-pore curr

98 regulate their expression, is not displaced proximally in the absence of definitive endoderm.

99 icantly reduced, suggesting SLAP-2 functions proximally in the antigen receptor signaling cascade.

100 aphical area, with the increase being larger proximally in the jejunum than distally in the ileum.

101 ter denervation and more commonly originated proximally in the jejunum, but the velocity of migration

102 sorted into separate but adjacent fascicles proximally in the limb, long before they reached the mus

103 MA) and ionomycin, suggesting that SLAP acts proximally in the TCR signaling pathway.

104 ost mesenchyme and can also be detected more proximally, in between the forming skeletal elements.

105 A4.1 proximally inhibits beta(1) integrin-dependent adhesion

106 e developing limb skeleton, and one situated proximally, initiating transcription in neural epitheliu

107 promoter sequences that have the property of proximally interfering with upstream enhancer elements i

108 PN in VAdc receive massive inhibitory input proximally intermingled with some presumably excitatory

109 distal proliferative zone and differentiate proximally into hypertrophic chondrocytes.

110 ead to a lower peak airway pressure measured proximally, intratracheal peak airway pressure was uncha

111 relapse indicating that this lesion type is proximally involved in AML evolution.

112 d D4Z4 heterochromatinization, which spreads proximally, leading to overexpression of FSHD genes in c

113 We show that the proximally localised core polarity protein Strabismus ac

114 We also establish recruitment by proximally localized Inturned to be a putative mechanism

115 t a model whereby, prior to hair initiation, proximally localized Mwh inhibits actin polymerization r

116 ose detected at index colonoscopy, and to be proximally located (odds ratio, 2.24; P < .001).

117 ons have a high risk for malignancy, whereas proximally located 0-Is or 0-IIa granular lesions have a

118 Large or proximally located adenomas are important indicators of

119 to distal dendrites and segregated from the proximally located CoA synapses.

120 We recently reported that deletion of three proximally located conserved areas (Area I-II-III) from

121 SSA/P were proximally located in (10/11) 90% of patients aged under

122 is required for motor axons to progress from proximally located intermediate targets to distally loca

123 We find that deletion of proximally located loops 8 and 9 in the 32 kDa catalytic

124 Mutation of these residues as well as proximally located lysine 980 results in suppression of

125 ought to propel themselves with specialized, proximally located muscles that retract and rotate the f

126 Proximally located neurons in the distal part of the sub

127 hat patients with SSPE mimic those with more proximally located PE in regards to their risk profile a

128 of thromboembolic disease compared with more proximally located pulmonary embolism (PE).

129 with CRISPR/Cas9-edited rs1198588 or a rare proximally located SZ risk variant showed altered MIR137

130 that of large-artery atherosclerosis in more proximally located vessel beds.

131 type, TP53 wild type, poorly differentiated, proximally located, occur at lower stages, and have the

132 All membrane-anchored, proximally located, oncogenic Ras isoforms can promote R

133 to 20+/-2 nl/min; P<0.05) despite unchanged proximally measured, single-nephron GFR (SNGFR) (42+/-5

134 gion contains mixed acidic and basic patches proximally (N-terminal), whereas it is largely acidic di

135 ainly distal PN dendrites, but some synapsed proximally next to large F1 boutons.

136 everal highly homologous copies located more proximally on chromosome 16.

137 e placed in the standard position as well as proximally on the leg and the forearm.

138 echnical difficulty if a clamp can be placed proximally on the portal vein.

139 ng Cdk5 activity causes the domain to shrink proximally or disappear altogether.

140 ted kidney; the partially obstructed kidney, proximally or distally obstructed, with mild to severe o

141 Fasciculation potentials (FPs) may arise proximally or distally within the peripheral nervous sys

142 OEs leads us to propose a H-bond between the proximally oriented His207 ring and the carboxylate of A

143 pressure waveform resulting in an additional proximally originating deceleration wave during systole.

144 that begin in distal dendrites and progress proximally over time.

145 , through the controlled release of promoter-proximally paused Pol II into productive RNA synthesis.

146 tential interconnected functions of promoter-proximally paused Pol II.

147 e presence of constitutively bound, promoter-proximally paused Pol IIs at some E2-regulated promoters

148 nd Egr2, immediate-early genes with promoter-proximally paused polymerases, but does not affect expre

149 monstrate that GAF acts upstream of promoter-proximally paused RNA polymerase II (Pol II) formation (

150 Most human genes are loaded with promoter-proximally paused RNA polymerase II (Pol II) molecules t

151 Release of promoter-proximally paused RNA polymerase II (RNAPII) is a recent

152 escent sensor for the selective detection of proximally phosphorylated protein sites, suitable for ap

153 Specifically, proximally phosphorylated residues are hallmarks of cert

154 tory duct that results in obstruction of the proximally placed seminal vesicle.

155 The result was a large area of proximally pointing hairs in this region.

156 short DOG1 protein isoform produced from the proximally polyadenylated DOG1 mRNA is a key player in t

157 rocessing complex required for production of proximally polyadenylated functional DOG1 transcript.

158 This is corroborated by the finding that the proximally polyadenylated short DOG1 mRNA is translated

159 ylation of its C-terminal domain and remains proximally positioned at the promoter for hours.

160 ntext of the complete viral genome, however, proximally positioned enhancer sequences are unable to c

161 cancer-causing genes are unexpectedly often proximally positioned in the chromosome and share loci w

162 Proximally positioning P4 enhancer factor-binding sequen

163 Thus, NO and CO act proximally, presumably as heme ligands binding to the ox

164 injury mortality (SIM) with mortality from 3 proximally ranked top 10 causes of death: diabetes, infl

165 threat-detection and -response systems that proximally regulate autonomic induction of the CTRA.

166 levels, suggesting that CD2+ leukocytes may proximally regulate IL-20.

167 We identify regions consisting of tandem or proximally repetitive short DNA sequences, including som

168 lly large backward compression wave, whereas proximally, severe left ventricular outflow tract obstru

169 eceded at a one-half theta cycle interval by proximally targeted Schaffer collateral activity, tempor

170 t ascending inputs activate mainly or solely proximally targeting, parvalbumin-containing "fast-spiki

171 es, and monophasic decays, consistent with a proximally terminating synapse.

172 yed interval, they were more likely to occur proximally than a comparable number of meiotic crossover

173 (29H), T(32H), and T(34H) that extended less proximally than T(30H) permitted male fertility when opp

174 ns exhibit cytoplasmic extradenticle whereas proximally the protein is nuclear.

175 As autophagosomes move distally to proximally, they undergo maturation and become increasin

176 Injured cortical axons were eliminated proximally through a two-phase retraction process, which

177 of conduction block in the inferior pathway proximally, thus extending the length of the retrograde

178 y condensation of water-soluble silicic acid proximally to biomolecular interfaces throughout the org

179 nt pre-mRNAs cause U1 and Malat1 to localize proximally to chromatin at active genes, demonstrating t

180 PC1 acts proximally to CPE in the pathway of post-translational p

181 ured from up to four patched neurons located proximally to each other.

182 haracterized hESC enhancers, and are located proximally to genes expressed in hESCs and the epiblast.

183 cted to the feet and toes but extending more proximally to involve the legs and hands with time.

184 e sequences imposing variegation are located proximally to Ly49 genes.

185 Many epithelial cancers develop proximally to microbial communities, which are physicall

186 They initially localized proximally to mutating B cells, secreted interleukin 21

187 f promoter escape by removing downstream DNA proximally to positions 40/42.

188 ein kinase ArnS (Saci_1181) which is located proximally to the archaellum operon was identified.

189 layer of parallel collagen fibers attaching proximally to the base of the medial epicondyle of the h

190 Remaining chromaffin vesicles lined up proximally to the cell membrane in preparation for exocy

191 Whereas a tag from RepA protein crosslinked proximally to the flexible N domains, the ssrA sequence

192 ta-globin gene family during ontogeny reside proximally to the genes and immediately 5' to the human

193 yosin heavy chain promoter (alphaMHC) placed proximally to the human iPLA2gamma coding sequence that

194 ed in bladder neoplasia located distally and proximally to the MTS locus within p22-23 and p11-13 reg

195 at drives membrane invagination is nucleated proximally to the plasma membrane, opposite to the orien

196 Rgg binds to DNA proximally to the speB promoter (PspeB) to activate tran

197 s of subthalamic deep brain stimulation both proximally to the stimulation site and distally through

198 sting that proteasome binding positions Ubp6 proximally to the substrate translocation channel.

199 l pathway, which has been found to innervate proximally to the SVZ, causes motor and cognitive impair

200 s ligament (IOL) coursed obliquely to attach proximally to the tibia and insert distally in the fibul

201 rprisingly, transcription does initiate, but proximally to the UAS, regardless of its location.

202 t the site of impulse initiation in the cell proximally toward the soma and neurites receiving synapt

203 4 h depolarization, lengthened and relocated proximally toward the soma.

204 to the transmural incision either propagated proximally toward the stimulation site and collided with

205 Attempts to trace excitability measures proximally towards the site of block were unsuccessful,

206 Transcriptional profile of proximally transformed mosaic wing epithelium and functi

207 to those of the most advanced lesion removed proximally (up to the junction of the splenic flexure an

208 This result suggests that Z-DNA formation proximally upstream of a promoter is sufficient to demar

209 e signaling molecule(s) at the same level or proximally upstream of the MAPKKK level.

210 d(CG)n dinucleotide repeat sequence located proximally upstream of the TATA box enhances transcripti

211 Proximally, ureteral strictures and symptomatic retrocav

212 VH-TCFAs that remained VH-TCFAs located more proximally (values are median [interquartile range]) (16

213 e performed parallel to the popliteal tendon proximally was added to our routine study in patient kne

214 use chylomicron production is most efficient proximally we examined whether CD36 function is importan

215 In the mesenchyme Dlx2 is expressed proximally, whereas in oral epithelium it is expressed d

216 mped and the right iliac vein was controlled proximally with a double wrapped vessel-loop to contain

217 accharides and/or chitin that are associated proximally with lipid membrane constituents.

218 y along the apical dendrite and, on average, proximally with respect to OSN synapses.

219 These observations place Barx1 proximally within a Wt1 pathway of spleen development an

220 ta are consistent with a Src kinase activity proximally within DAP12 signaling, DAP12 also appears to

221 ed homeobox genes expressed distally but not proximally within the arches.

222 Gastric acidity extended more proximally within the LES in the large WC group, compare

223 that affect the turnover of repeats located proximally within the telomeric DNA are poorly defined.