ライフサイエンスコーパス: pseudoautosomal

1 mosome are nonrecombining, while the rest is pseudoautosomal.

2 ne might be in a state of transition between pseudoautosomal and X-unique locations.

3 orangutan non-coding divergence at the Xp/Yp pseudoautosomal boundary (K=3.5%) and in the SYBL1 gene

4 gene Fxy (also known as MID1 [7]) spans the pseudoautosomal boundary (PAB) in the laboratory mouse (

5 In particular, data from the mouse pseudoautosomal boundary (PAB) suggested that locally in

6 clease recognition site just proximal to the pseudoautosomal boundary by homologous recombination.

7 ously described a gene, Fxy , that spans the pseudoautosomal boundary in mice such that the first thr

8 nd Y chromosomes followed by movement of the pseudoautosomal boundary to create X-unique regions.

9 chromosome, which we have used to define the pseudoautosomal boundary, that is, the point of divergen

10 roximately 0.2-cM interval that includes the pseudoautosomal boundary.

11 located in Xp22.3 in humans, proximal to the pseudoautosomal boundary.

12 This constitutes the first report of a pseudoautosomal DNA marker for plant sex chromosomes.

13 ide non-coding divergence (K) to that in the pseudoautosomal genes which were reported to recombine m

14 Defects of the pseudoautosomal homeobox gene SHOX were previously shown

15 We have named the gene PHOG, for pseudoautosomal homeobox-containing osteogenic gene.

16 linked genes are increased relative to their pseudoautosomal homologs, both at synonymous and amino a

17 A pseudoautosomal location for a dosage-sensitive locus in

18 leles occur on both the X and Y chromosomes (pseudoautosomal loci).

19 Recombination rates between this pseudoautosomal marker and the differentiating portion o

20 completed using 292 autosomal and three X-Y pseudoautosomal markers.

21 BAC57, containing the pseudoautosomal microsatellite INRA3O, mapped to the dis

22 Clones containing pseudoautosomal or sex-linked microsatellites were isola

23 Pseudoautosomal PacI restriction fragments, up to 2 Mb i

24 complex (MHC) and one in the sex chromosomal pseudoautosomal pairing region PAR1.

25 g male meiosis is restricted to the terminal pseudoautosomal pairing regions.

26 t 170-fold higher for synonymous sites) when pseudoautosomal (present on both the X and Y chromosomes

27 nes located in the human and orangutan Xp/Yp pseudoautosomal region (p-PAR), where recombination is o

28 The S. latifolia pseudoautosomal region (PAR) includes several genes extr

29 The pseudoautosomal region (PAR) is a segment of shared homo

30 distal one-third of the long arm, where the pseudoautosomal region (PAR) is located terminally.

31 The pseudoautosomal region (PAR) of mammalian sex chromosome

32 The pseudoautosomal region (PAR) of mammalian sex chromosome

33 le for LWD, SHOX, localizes to the short-arm pseudoautosomal region (PAR) of the X and Y chromosomes.

34 that this molecular marker is located in the pseudoautosomal region (PAR) of the X and Y chromosomes.

35 id sulfatase (Sts) as this is located in the pseudoautosomal region (PAR) of the X-chromosome and con

36 The pseudoautosomal region (PAR) was strongly associated wit

37 Six of 783 non-pseudoautosomal region (PAR) X-chromosome genes (ATRX, C

38 cloned and mapped to Xp22.3, proximal to the pseudoautosomal region (PAR).

39 over in a very small region of homology, the pseudoautosomal region (PAR).

40 ion (SDR) and proportionally elevated in the pseudoautosomal region (PAR).

41 mosomes, consistent with localization to the pseudoautosomal region (PAR).

42 lished linkage to the marker DXYS6814 in the pseudoautosomal region (PAR1) of the X and Y chromosomes

43 s hypothesis by studying the human short-arm pseudoautosomal region (PAR1), which recombines between

44 icated a critical region of <2 Mb within the pseudoautosomal region (PAR1).

45 L1 gene (K=2.7%), located in the human Xq/Yq pseudoautosomal region (q-PAR), where recombination is k

46 G gene, which spans the boundary between the pseudoautosomal region 1 (PAR1) and the X-specific regio

47 x whole genome sequence (WGS), including the pseudoautosomal region 1 (PAR1).

48 avy chain gene IGH@ on 14q32 to CRLF2 in the pseudoautosomal region 1 of Xp22.3/Yp11.3, whereas 10 (3

49 SFR alpha chain, encoded in the X-chromosome pseudoautosomal region 1.

50 The 320-kb human pseudoautosomal region 2 (PAR2) at the tips of the long

51 pseudoautosomal region in distal Xq28 (PAR2; pseudoautosomal region 2), gave a combined maximum LOD s

52 , which is X-linked, human SPRY3 maps to the pseudoautosomal region 2; however, the human Y-linked al

53 We have also refined the pseudoautosomal region and boundary in the cat and show

54 The OA1 gene is located close to the pseudoautosomal region and predicts a novel protein whos

55 ease/decrease in sharing when markers in the pseudoautosomal region are analyzed.

56 on the mammalian Y chromosome outside of the pseudoautosomal region do not recombine with those on th

57 We examined the long arm XY pseudoautosomal region for linkage to asthma, serum IgE,

58 polymorphisms at the distal tip of the Xp/Yp pseudoautosomal region in 47,XYY males, their parents an

59 Marker DXYS154, which is located within the pseudoautosomal region in distal Xq28 (PAR2; pseudoautos

60 however, this gene spans the boundary of the pseudoautosomal region in mouse but not in humans.

61 the distal end of the bivalent acts as a neo-pseudoautosomal region in these males.

62 We find that, while PolII in the pseudoautosomal region occupies both chromosomes at simi

63 obligatory exchange occurs in PAR1, an Xp/Yp pseudoautosomal region of 2.6 Mb, which creates a male-s

64 It has been proposed that the pseudoautosomal region of mammals has evolved by sequent

65 One was a 1.6-Mb deletion in the pseudoautosomal region of one maternal X chromosome enco

66 e pairs were preferentially clustered in the pseudoautosomal region of the sex chromosomes and locate

67 ature homeobox-containing gene (SHOX) in the pseudoautosomal region of the sex chromosomes may cause

68 ce for close linkage to three markers in the pseudoautosomal region of the sex chromosomes.

69 PCR assays potentially originating from the pseudoautosomal region or other areas of X-Y or autosome

70 GYG2 is outside the pseudoautosomal region PAR1 but still in a region of X-Y

71 t Moa1 is located much farther away from the pseudoautosomal region than its human homolog.

72 ls on the Y chromosome short arm outside the pseudoautosomal region that are homologous to Xq2l.3.

73 ic map was 118.7 cM (female only) and of the pseudoautosomal region was 13.0 cM (male only).

74 lation: SYBL1, a housekeeping gene in the Xq pseudoautosomal region, and GPC3, a tissue-specific gene

75 elative to autosomes, including those in the pseudoautosomal region, and the male-bias increases afte

76 st that all CpG islands on Xq, including the pseudoautosomal region, are subject to X inactivation-in

77 In addition to the genes from the pseudoautosomal region, which have long been anticipated

78 nce increases with genetic distance from the pseudoautosomal region.

79 ice because of a 4-Megabase expansion of the pseudoautosomal region.

80 n sex-determining gene DMRT1 and ends at the pseudoautosomal region.

81 se characteristics are those residing in the pseudoautosomal regions (PAR) of the sex chromosomes.

82 s pairing and exchange occurs within the two pseudoautosomal regions (PARs) together comprising <5% o

83 ersity among species in their composition of pseudoautosomal regions and degree of Z/W differentiatio

84 Sequence exchange outside the pseudoautosomal regions could play a role in protecting

85 human X-linked genes outside the X-Y pairing pseudoautosomal regions escape X-inactivation.

86 Pseudoautosomal regions have been described in a broad t

87 red regions, analogous to the nonpairing and pseudoautosomal regions of animal sex chromosomes.

88 However, with this approach, data from the pseudoautosomal regions on the X chromosome pose special

89 Outside the pseudoautosomal regions on the X chromosome, we similarl

90 stages from the mating-type locus toward the pseudoautosomal regions was not found, but evidence of s

91 V system) recovering the sex determining and pseudoautosomal regions, and then to the mating-type chr

92 Outside the pseudoautosomal regions, the mammalian sex chromosomes a

93 x linked, not including those in recombining pseudoautosomal regions.

94 mosome lengths, flanked at either end by two pseudoautosomal regions.

95 mice, there is synapsis between the X and Y pseudoautosomal regions; in XSxr(a)O mice, with a single

96 at it is still ongoing in the recombining or pseudoautosomal, regions (PARs) of these chromosomes.

97 om a chromosomal rearrangement that includes pseudoautosomal sequences and affects XY pairing.

98 Only Smcx and the pseudoautosomal Sts gene on the mouse X chromosome have

99 Satisfying the requirement for pseudoautosomal synapsis by providing a pairing partner

100 adjacent like repeats, as seen at the Xp/Yp pseudoautosomal telomere.

101 nscripts tested here, 34 (three of which are pseudoautosomal) were expressed in as many as nine Xi hy

102 mcx gene is the first known example of a non-pseudoautosomal X-linked gene in mouse that normally esc