ライフサイエンスコーパス: pseudopodia

1 s and PI3K activation occur spontaneously on pseudopodia.

2 a5beta1 integrin to the leading edge of cell pseudopodia.

3 ntercellular separation, and the presence of pseudopodia.

4 ibited the activity of the Rac GTPase within pseudopodia.

5 followed by disengagement and retraction of pseudopodia.

6 -2, beta-arrestin-2, and activated ERK1/2 to pseudopodia.

7 defects, including the formation of lateral pseudopodia.

8 tly juxtaposed multiple onion-like layers of pseudopodia.

9 focal adhesions was observed along extending pseudopodia.

10 ine 19 is elevated in growing and retracting pseudopodia.

11 C phosphorylation associated with retracting pseudopodia.

12 hich the Dictyostelium cell actively extends pseudopodia.

13 tigen has been observed to extend long, thin pseudopodia.

14 treated PB T cells extend F-actin-containing pseudopodia.

15 displayed numerous extensions suggestive of pseudopodia.

16 did not inhibit the extension of actin-rich pseudopodia along IgG-opsonized sheep erythrocytes, but

17 Rapid formation and extension of pseudopodia and filopodia were also observed, and transi

18 specific biosensors accumulated at extending pseudopodia and in phagosomal cups in trophozoites expos

19 ents and mice, formed more frequent multiple pseudopodia and lost their directionality as they migrat

20 he cells with more intensive staining on the pseudopodia and membrane ruffles.

21 rc" of Rac2 at the leading edge of leukocyte pseudopodia and PLD2 physically posterior to this wave o

22 Leukocytes that did not project pseudopodia and spread in response to low shear stress c

23 lication of fluid shear many cells projected pseudopodia and spread on the glass surface.

24 of V-1 in Dictyostelium reduced the size of pseudopodia and the cortical content of Arp2/3 and induc

25 common ancestor) had a cilium, mitochondria, pseudopodia, and myosins with three contrasting domain c

26 affolding, initiate the assembly of invasive pseudopodia, and propagate transmigration.

27 at is characterized by the extension of long pseudopodia, and the association of the GTPase with alph

28 Lasp-1 colocalize with actin at the tips of pseudopodia, and this localization is maintained by cont

29 Pseudopodia are especially problematic because their cyt

30 During the second slow phase, pseudopodia are extended from local regions of the cell

31 morphology, but instead extend mislocalized pseudopodia around the cell and exhibit decreased veloci

32 formation of actin-rich protrusions such as pseudopodia, but regulation of the dynamic localization

33 d actin networks comprising lamellipodia and pseudopodia by virtue of its ability to cap the actin fi

34 cytoskeletal-associated signals in purified pseudopodia directed to undergo growth or retraction.

35 d structures, including membrane ruffles and pseudopodia during chemotaxis.

36 SCAP RNAi or 25-HC inhibited VEGF-induced pseudopodia extension and migration of ECs.

37 and RhoA are distinct pathways that control pseudopodia extension and retraction, respectively, thro

38 e activity prevented MLC phosphorylation and pseudopodia extension but not retraction.

39 ization of the actin cytoskeleton, polarized pseudopodia extension, and chemotaxis.

40 edback loop to maintain CAS/Crk coupling and pseudopodia extension.

41 R4 or CCR7 mediates actin polymerization and pseudopodia formation, and subsequently induces chemotac

42 ine does not exhibit constitutive migration, pseudopodia formation, or trypsin secretion; in these ce

43 EP4, and CEP5 in NIH-3T3 fibroblasts induced pseudopodia formation.

44 binding domain mutant of CEP2 did not induce pseudopodia formation.

45 k as an essential scaffold for Rac1-mediated pseudopodia growth and retraction, and illustrate spatio

46 Pseudopodia growth requires assembly of a p130Crk-associ

47 ukocytes from FAN-deficient embryos protrude pseudopodia in all directions instead of having one clea

48 thelial junctions were retained and extended pseudopodia into and through the junctions, thereby incr

49 Human T-lymphocytes extended pseudopodia into endothelial cells in caveolin- and F-ac

50 The extension of pseudopodia is followed by periods of growth in the cell

51 Acquisition of elongated cells with pseudopodia is observed when corneal endothelial cells (

52 Nine eyes had pseudopodia lentis, whereas all 10 had glass wool-like v

53 er, Rac1-null fibroblasts translocated using pseudopodia-like protrusions without lamellipodia, migra

54 Nonmotile cells extend and retract pseudopodia-like structures in a random manner, whereas

55 stem in which migrating ECs display branched pseudopodia morphodynamics similar to those in living ze

56 MT1-MMP's arrival at the plasma membrane in pseudopodia, N-WASP stabilized MT1-MMP via direct tether

57 hich is highlighted by impaired formation of pseudopodia networks due to marked cytoskeletal alterati

58 oncentrated at the leading edge of extending pseudopodia of Fos-transformed Rat-1 cells, and was main

59 wide scale, RNAs that localize in protruding pseudopodia of mouse fibroblasts in response to migrator

60 lipodia that is similar to ezrin function in pseudopodia of transformed fibroblasts.

61 ted the rate of protrusion and retraction of pseudopodia on fibronectin-coated surfaces.

62 in cross-linked webs (as in lamellipodia or pseudopodia) or parallel bundles (as in filopodia).

63 nestrations, formation of irregular platelet pseudopodia, platelet lysis, lipid vesicle leakage, and

64 romoted trafficking of MT1-MMP into invasive pseudopodia, primarily from late endosomes, from which i

65 tend to spread anisotropically, by extending pseudopodia randomly distributed along the cell membrane

66 -actin-rich leading edge and do not protrude pseudopodia, resulting in very poor cell motility.

67 tion of RhoA activity specifically decreased pseudopodia retraction but not extension.

68 regulation of Rac1 activity and induction of pseudopodia retraction.

69 roteomic and functional analysis of isolated pseudopodia revealed the Lim, actin, and SH3 domain prot

70 nce microscopy and biochemical enrichment of pseudopodia showed that type II regulatory subunits of P

71 in axo-glial interactions, we modified the 'pseudopodia' sub-fractionation system and isolated the p

72 a-arrestin-1 colocalizes with p85 within the pseudopodia, suggesting that beta-arrestin-1 association

73 role in mediating the assembly of elongated pseudopodia that are instrumental in matrix degradation.

74 n and contributes to the global extension of pseudopodia that occurs prior to polarization and direct

75 g an initial stage involving invasive T-cell pseudopodia that penetrate deeply into the antigen-prese

76 roduction begins with the extension of large pseudopodia that use unique cortical bundles of microtub

77 They become more spherical and extrude pseudopodia, their fibrinogen receptors are activated, c

78 the metastatic cascade by inserting invasive pseudopodia through breaches in the basement membrane (B

79 ndle, or dome-shaped cells, with exploratory pseudopodia to noninvasive cuboidal cells that formed ce

80 region narrowed to a smaller area from which pseudopodia were extended toward the target.

81 The settled neutrophils lacked pseudopodia, were impaired in motility, and were envelop

82 oss of polarity and produce multiple lateral pseudopodia when placed in a chemoattractant gradient.

83 in Lasp-1 in membrane ruffles at the tips of pseudopodia, where both proteins are necessary for pseud

84 RK1/2 scaffolding complex is enriched in the pseudopodia, where it appears to prolong ERK1/2 activati

85 2 caused platelets to form fenestrations and pseudopodia which were longer and thinner than those cau

86 ellipodia and at the periphery of fibroblast pseudopodia, which are regions of high motility.

87 aplanospores of the parasite produced filose pseudopodia, which contained fine fibers the diameter of

88 Motility refers to the random extension of pseudopodia, which may be driven by spontaneous actin wa