ライフサイエンスコーパス: pseudorabies

1 Control viruses, including pseudorabies, adeno-associated, or replication-deficient

2 In addition, UL11 homologs from pseudorabies and Marek's disease herpesviruses were also

3 two isogenic strains of a neurotropic virus (pseudorabies, Bartha) tagged with either green or red fl

4 s, which caused the recent devastating swine pseudorabies outbreak in China.

5 y in pigs and the promise to control current pseudorabies outbreak.

6 The alpha-herpes virus (pseudorabies, PRV) was used to observe central nervous s

7 of the advantages and limitations of herpes, pseudorabies, rabies, adeno-associated, lentivirus, and

8 d using green fluorescent protein expressing pseudorabies virus (GFP-PRV) to (1) characterize age-dep

9 A strain of pseudorabies virus (PRV 152) isogenic with the Bartha st

10 itreal injection of the attenuated strain of pseudorabies virus (PRV Bartha) results in transneuronal

11 ntraocular injection of the Bartha strain of pseudorabies virus (PRV Bartha) results in transsynaptic

12 rus (HSV), varicella-zoster virus (VZV), and pseudorabies virus (PRV) all utilize a complex of two gl

13 well as for the animal herpesviruses porcine pseudorabies virus (PRV) and bovine herpesvirus 1 (BHV-1

14 entified by immunohistochemical detection of pseudorabies virus (PRV) and corticotropin-releasing fac

15 are the most widely used method to visualize pseudorabies virus (PRV) and herpes simplex virus (HSV)

16 he gD glycoprotein of the alphaherpesviruses pseudorabies virus (PRV) and herpes simplex virus 2 (HSV

17 Pseudorabies virus (PRV) and herpes simplex virus type 1

18 Both Pseudorabies virus (PRV) and human Herpes simplex virus

19 3 in herpes simplex virus type 1 (HSV-1) and pseudorabies virus (PRV) and ORF66 in varicella-zoster v

20 ane proteins encoded by the alphaherpesvirus pseudorabies virus (PRV) are internalized after reaching

21 The membrane proteins gI and gE of Pseudorabies virus (PRV) are required for viral invasion

22 The structure of pseudorabies virus (PRV) capsids isolated from the nucle

23 The alphaherpesvirus pseudorabies virus (PrV) establishes latency primarily i

24 Like other alphaherpesviruses, pseudorabies virus (PrV) exhibits restricted gene expres

25 d PSPMNs by using recombinant strains of the pseudorabies virus (PRV) for trans-synaptic tract tracin

26 d PSPMNs by using recombinant strains of the pseudorabies virus (PRV) for transsynaptic tract-tracing

27 pothesis, we used recombinant strains of the pseudorabies virus (PRV) for transsynaptic tract-tracing

28 rograde transport of an attenuated strain of pseudorabies virus (PRV) from the nucleus accumbens was

29 endent retrograde transneuronal transport of pseudorabies virus (PRV) from the stomach wall.

30 determine the role of internalization of the pseudorabies virus (PRV) gE and gI proteins, we construc

31 The pseudorabies virus (PRV) gE gene encodes a multifunction

32 A full-length clone of the 142-kb pseudorabies virus (PRV) genome was constructed as a sta

33 Pseudorabies virus (PRV) glycoprotein E (gE) is a type I

34 ynaptic tracing with peripheral injection of pseudorabies virus (PRV) has been extensively characteri

35 K in herpes simplex virus type 1 (HSV-1) and pseudorabies virus (PRV) have been well studied.

36 using transneuronal retrograde transport of pseudorabies virus (PRV) in normal animals and in animal

37 ction of the transneuronal retrograde tracer pseudorabies virus (PRV) in rats, we previously localize

38 s, was mapped using the transneuronal tracer pseudorabies virus (PRV) in the ferret.

39 cellular virions and axonal assemblies after pseudorabies virus (PRV) infection of cultured neurons.

40 After pseudorabies virus (PRV) infection of murine L929 cells,

41 the host gene expression profile after acute pseudorabies virus (PRV) infection of the CNS using Affy

42 models of viral egress from neurons by using pseudorabies virus (PRV) infection of the rat retina: do

43 nal spread of herpes simplex virus (HSV) and pseudorabies virus (PRV) infection, a culture system con

44 nduced after herpes simplex virus type 1 and pseudorabies virus (PRV) infections of rat embryonic fib

45 When the swine alphaherpesvirus pseudorabies virus (PRV) infects the rat retina, it repl

46 ed by retrograde trans-synaptic migration of pseudorabies virus (PRV) injected into the adrenal gland

47 Using the retrograde, transsynaptic tracer pseudorabies virus (PRV) injected into the BAT of mice,

48 astric nerves transected, were infected with pseudorabies virus (PRV) injected into the external uret

49 ia the transsynaptic retrograde transport of pseudorabies virus (PRV) injected into the kidneys of ra

50 ted neurons in the preoptic region following pseudorabies virus (PRV) injections into either the supe

51 Pseudorabies virus (PRV) injections were made into the l

52 sneuronal tracing studies using injection of pseudorabies virus (PRV) into either the diaphragm or re

53 studied after injecting the Bartha strain of pseudorabies virus (PRV) into the sciatic nerve to provi

54 epithelial cells, alphaherpesviruses such as pseudorabies virus (PRV) invade axons of peripheral nerv

55 Pseudorabies virus (PRV) is a broad host range, swine al

56 Transneuronal spread of pseudorabies virus (PRV) is a multistep process that req

57 Pseudorabies virus (PRV) is a useful tracer that is retr

58 Pseudorabies virus (PRV) is an alphaherpesvirus related

59 Glycoprotein E (gE) gene of pseudorabies virus (PRV) is conserved among diverse alph

60 Pseudorabies virus (PRV) mutants lacking the Us9 gene ca

61 Retrograde infection by pseudorabies virus (PRV) of neuronal populations neighbo

62 by inoculating the ventral stomach wall with pseudorabies virus (PRV) on postnatal day 1 (P1), P4, or

63 simplex virus (HSV) entry activity, but not pseudorabies virus (PRV) or bovine herpesvirus 1 (BHV-1)

64 d the retrograde transneuronal tracer Bartha-pseudorabies virus (PRV) or the retrograde marker choler

65 ane protein present in the lipid envelope of pseudorabies virus (PRV) particles in a unique tail-anch

66 Toward this end, we generated a novel pseudorabies virus (PrV) recombinant in which a 282-bp r

67 In this report, we describe construction of pseudorabies virus (PRV) recombinants that efficiently e

68 Here, we refine this map using pseudorabies virus (PRV) retrograde tracing, indicating

69 The attenuated pseudorabies virus (PRV) strain Bartha contains several

70 After intraocular injection of the virulent pseudorabies virus (PRV) strain Becker into late-stage c

71 To accomplish this, we have constructed pseudorabies virus (PRV) strains in which viral propagat

72 , but partial deletions generated in HSV and pseudorabies virus (PrV) suggest an additional function

73 ly(A) fraction of the lytic transcriptome of pseudorabies virus (PRV) throughout a 12-hour interval o

74 This study used the transneuronal tracer pseudorabies virus (PRV) to investigate the CNS network

75 ns were identified by immunogold labeling of pseudorabies virus (PRV) transported retrogradely and tr

76 The subcellular distribution of the pseudorabies virus (PRV) UL28 protein was examined by in

77 The pseudorabies virus (PRV) UL54 homologs are important mul

78 We demonstrate here that the pseudorabies virus (PRV) Us2 protein is synthesized earl

79 The pseudorabies virus (PRV) Us3 gene is conserved among the

80 The protein product of the pseudorabies virus (PRV) Us9 gene is a phosphorylated, t

81 Pseudorabies virus (PRV) Us9 is a small, tail-anchored (

82 In this report, we demonstrate that the pseudorabies virus (PRV) Us9 protein is present in infec

83 s simplex virus (HSV) and, as reported here, pseudorabies virus (PRV) utilize the ESCRT apparatus to

84 nal sorting and transport of fully assembled pseudorabies virus (PRV) virions is dependent on the vir

85 e provide an initial characterization of the pseudorabies virus (PRV) VP22 homologue.

86 Pseudorabies virus (PRV) was injected into the pancreas

87 tracing experiments were performed in which pseudorabies virus (PRV) was injected into the stellate

88 riments, the retrograde transneuronal tracer pseudorabies virus (PRV) was microinjected into the CEAm

89 A replication-competent gL-null pseudorabies virus (PrV) was shown to express a gDgH hyb

90 dies, we compared gH of the alphaherpesvirus pseudorabies virus (PrV) with gH of the gammaherpesvirus

91 Pseudorabies virus (PRV), a broad host range alphaherpes

92 Pseudorabies virus (PRV), a member of the Alphaherpesvir

93 Pseudorabies virus (PRV), a neurotropic swine alpha herp

94 brane glycoproteins gE and gI are encoded by pseudorabies virus (PRV), a neurotropic, broad-host-rang

95 lenic function was accomplished by injecting pseudorabies virus (PRV), a retrograde transynaptic trac

96 that the amino-terminal one-third of gC from pseudorabies virus (PRV), a swine herpesvirus, includes

97 Pseudorabies virus (PRV), a swine neurotropic alphaherpe

98 g vesicular stomatitis (VSV), Sindbis virus, pseudorabies virus (PRV), adeno-associated virus (AAV),

99 Using pseudorabies virus (PRV), an alphaherpesvirus capable of

100 Pseudorabies virus (PRV), an alphaherpesvirus related to

101 Previous studies showed that proteins from pseudorabies virus (PRV), an alphaherpesvirus, localize

102 erpes simplex viruses (HSV) 1 and 2, porcine pseudorabies virus (PRV), and bovine herpesvirus 1 (BHV-

103 (BHV-1), equine herpesvirus type 1 (EHV-1), pseudorabies virus (PRV), and varicella-zoster virus (VZ

104 pesviruses, such as herpes simplex virus and pseudorabies virus (PRV), are neuroinvasive dsDNA viruse

105 U(S)11c119.3 cells are fully susceptible to pseudorabies virus (PRV), as shown by single-step growth

106 The related animal herpesvirus, pseudorabies virus (PRV), encodes a homologous set of gl

107 sviruses, herpes simplex virus 1 (HSV-1) and pseudorabies virus (PRV), have suggested that UL37 plays

108 pes viruses: herpes simplex virus (HSV1) and pseudorabies virus (PrV), human immunodeficiency virus t

109 peroxidase conjugated to colloidal gold, or pseudorabies virus (PRV), into the nuclear core of the r

110 In the swine pathogen pseudorabies virus (PRV), mutant viruses with internal d

111 Alphaherpesviruses, including pseudorabies virus (PRV), spread directionally within th

112 Live attenuated vaccine strains of pseudorabies virus (PRV), such as PRV Bartha, are among

113 lex virus 1 (HSV-1), HSV-2, and veterinarian pseudorabies virus (PRV), that infect the peripheral ner

114 In pseudorabies virus (PRV), the Us9 protein is a 98-amino-

115 ished retrograde transneuronal viral tracer, pseudorabies virus (PRV), was injected into the ventral

116 The transneuronal tracer, pseudorabies virus (PRV), was used to identify pathways

117 Using a viral transneuronal tract tracer, pseudorabies virus (PRV), we also tested whether the com

118 Using pseudorabies virus (PRV), we have previously shown that

119 Using the neuroinvasive herpesvirus, pseudorabies virus (PRV), we show that the viral protein

120 cle-specific injection of an mRFP-expressing pseudorabies virus (PRV), which acts as a transsynaptic

121 Pseudorabies virus (PRV)-a retrograde transneuronal trac

122 s study were to identify the mechanism(s) of pseudorabies virus (PrV)-induced down-regulation of porc

123 nervous system, alphaherpesviruses-including pseudorabies virus (PRV)-use retrograde axonal transport

124 tion with virulent and attenuated strains of pseudorabies virus (PRV).

125 athways in rats using recombinant strains of pseudorabies virus (PRV).

126 te entry of herpes simplex viruses (HSV) and pseudorabies virus (PRV).

127 of gD (for example, HSV-1/Rid), and porcine pseudorabies virus (PRV).

128 following infection of the left kidney with pseudorabies virus (PRV).

129 a receptor for the porcine alphaherpesvirus pseudorabies virus (PRV).

130 el to study neuronal spread and virulence of pseudorabies virus (PRV).

131 -1), HSV-2, and the related alphaherpesvirus pseudorabies virus (PRV).

132 an alpha-herpes virus, the Bartha strain of pseudorabies virus (PRV).

133 DMV neurons projecting to the stomach using pseudorabies virus (PRV).

134 DA), and retrograde tracing with fluorescent pseudorabies virus (PRV).

135 onserved in varicella-zoster virus (VZV) and pseudorabies virus (PRV).

136 of two neurotropic herpesviruses: HSV-1 and pseudorabies virus (PRV).

137 emale Sprague-Dawley rats were infected with pseudorabies virus (PRV, Bartha's K-strain) by injection

138 nstructing a replication-competent strain of pseudorabies virus (PRV-263) that changes the profile of

139 train of the retrograde transneuronal tracer pseudorabies virus (PRV-Ba) was injected into rat choroi

140 e transneuronal tracer, the Bartha strain of pseudorabies virus (PRV-Ba), were injected into the uppe

141 tract tracing using an attenuated strain of pseudorabies virus (PRV-Bartha) was combined with immuno

142 S-specific transneuronal viral tract tracer, pseudorabies virus (PRV152) and demonstrated the sensory

143 , to identify GG premotoneurons, we injected pseudorabies virus (PRV152) into the GG muscle.

144 ed fluorophore expression from a recombinant pseudorabies virus (PRV263) carrying a Brainbow cassette

145 vulgaris leucoagglutinin (anterograde), and pseudorabies virus (transneuronal retrograde) tract-trac

146 g after inoculation of the stomach wall with pseudorabies virus 152, a viral label that reports enhan

147 e poliovirus, herpesvirus, rabies virus, and pseudorabies virus all utilize neuronal retrograde trans

148 following infection with the closely related pseudorabies virus and observed similar perimeters of gl

149 ynaptically labeled from the distal colon by pseudorabies virus and several of these were also retrog

150 The glycoproteins I and E of pseudorabies virus are important mediators of cell-to-ce

151 s simplex virus, varicella zoster virus, and pseudorabies virus are neurotropic pathogens of the Alph

152 Using pseudorabies virus as a model, we infected neuron cell b

153 In this report, we have used pseudorabies virus as a neuroanatomical tract tracer in

154 ame animals by injection of a recombinant of pseudorabies virus Bartha (PRV) into the contralateral v

155 he transsynaptic retrograde transport of the pseudorabies virus Bartha (PRV-Bartha) strain has become

156 labeling of the phrenic motoneuron pool with pseudorabies virus demonstrated a substantial number of

157 Pseudorabies virus encodes a membrane protein (Us9) that

158 By using pseudorabies virus expressing green fluorescence protein

159 rions, epithelial cells infected by HSV-1 or pseudorabies virus following ADS express fewer than two

160 milarities and differences between HSV-1 and pseudorabies virus gE.

161 icial chromosome (BAC) containing the 142-kb pseudorabies virus genome was constructed such that the

162 sons with homologous HSV-2 gH/gL and partial pseudorabies virus gH structures support the domain boun

163 Recently, a pseudorabies virus glycoprotein D (gD)-green fluorescent

164 The Bartha strain of pseudorabies virus has several recognized mutations, inc

165 naptic labeling from the adrenal gland using pseudorabies virus identified presympathetic GABAergic n

166 ficking, we analyzed the axonal transport of pseudorabies virus in the presence and absence of pUS9.

167 al afferent pathways can be identified after pseudorabies virus infection of the kidney.

168 sitive neurones in the LH were labelled with pseudorabies virus injected into the liver of parasympat

169 erebral cortex were identified in rats after pseudorabies virus injections were made in functionally

170 Pseudorabies virus inoculated into the distal femoral me

171 Injection of pseudorabies virus into different regions of the MD or r

172 nsneuronally infected following injection of pseudorabies virus into rectus abdominis or transversus

173 injected the retrograde transynaptic tracer pseudorabies virus into single tensor tympani (TT) muscl

174 Injection of conditional pseudorabies virus into the brain of an LHRH::CRE mouse

175 injected a retrograde-specific strain of the pseudorabies virus into the rat OB and piriform cortex.

176 Fluorogold or green fluorescent pseudorabies virus labeled postganglionic neurons in the

177 We used transsynaptic anterograde pseudorabies virus labeling of fungiform taste papillae

178 The stability of interneuronal pseudorabies virus labeling patterns following lateral c

179 resembles in many respects the phenotype of pseudorabies virus lacking glycoproteins gM, gE, and gI.

180 Mutant pseudorabies virus lacking U(L)3.5 is deficient in viral

181 demonstrate that the pUL31 component of the pseudorabies virus nuclear egress complex is a condition

182 remotor interneurons with the trans-synaptic pseudorabies virus PRV-152 revealed the presence of burs

183 Specifically, we injected the conditional pseudorabies virus recombinant (BA2001) that can replica

184 Dual-labeling studies with pseudorabies virus recombinants also showed prephrenic i

185 The first method uses HSV-1 and pseudorabies virus recombinants that express one of thre

186 ransneuronal retrograde pathway tracing with pseudorabies virus revealed connectivity between MnPO VG

187 We constructed a pseudorabies virus strain that expressed Us9-GFP and tes

188 liver and epididymal white fat in mice using pseudorabies virus strains expressing different reporter

189 Two immunohistochemically distinct pseudorabies virus strains were injected into male Sprag

190 riments with ICP4 homologs revealed that the pseudorabies virus TAD is a potent activator of the gD p

191 Despite being a major component of the pseudorabies virus tegument, VP22 is not required for PR

192 We report the development of a pseudorabies virus that can be used for retrograde traci

193 Starting with derivatives of pseudorabies virus that encode a fluorescent protein fus

194 Here, the spread of pseudorabies virus through renal sensory pathways was ex

195 n subunit b retrograde tracing from rRPa and pseudorabies virus transynaptic retrograde tracing from

196 The resistance to pseudorabies virus was CD4(+) T cell dependent, because

197 Pseudorabies virus was injected into the wall of the ven

198 ntral nervous system neurons infected with a pseudorabies virus were examined in vitro by using whole

199 pathway, a retrograde transsynaptic tracer (pseudorabies virus) was injected into the orbicularis oc

200 rebral injections of an attenuated strain of pseudorabies virus, a neurotropic alpha herpesvirus that

201 s in the spinal cord, was characterized with pseudorabies virus, a retrograde transynaptic tracer.

202 Using pseudorabies virus, a transsynaptic tracer, in anestheti

203 Pseudorabies virus, an alpha-herpesvirus, is capable of

204 tructure of the N-terminal half of UL37 from pseudorabies virus, an alphaherpesvirus closely related

205 a subunit, Fluoro-Gold, the Bartha strain of pseudorabies virus, and biotinylated dextran amine.

206 simplex virus types 1 and 2 (HSV-1 and -2), pseudorabies virus, and bovine herpesvirus 1.

207 phaherpesviruses herpes simplex virus (HSV), pseudorabies virus, and bovine herpesvirus type 1.

208 ctures of gH/gL from herpes simplex virus 2, pseudorabies virus, and Epstein-Barr virus revealed dist

209 Cytomegalovirus, pseudorabies virus, and Sindbis virus all evoked a 2-log

210 ilar mutant of the related alphaherpesvirus, pseudorabies virus, and suggests that the glycoprotein r

211 lycoproteins of herpes simplex virus type 1, pseudorabies virus, and varicella-zoster virus, BHV-1 gI

212 fork movement in vivo during replication of pseudorabies virus, another herpesvirus.

213 Pseudorabies virus, Bartha's K strain, was injected into

214 virus 1 (EHV-1), varicella-zoster virus, and pseudorabies virus, but very little is known about the p

215 tween HSV1 and the related alphaherpesvirus, pseudorabies virus, in which the homologues of all three

216 ions of the SCN using the swine herpesvirus (pseudorabies virus, PRV) as a tool for transynaptic anal

217 r the retrograde transneuronal viral tracer, pseudorabies virus, was injected into the stellate sympa

218 an infectious clone of the alphaherpesvirus pseudorabies virus, we have made a collection of truncat

219 /Cas9 and Cre/Lox system against re-emerging Pseudorabies virus, which caused the recent devastating

220 ry associated with the hippocampus using the pseudorabies virus-Bartha strain (PRV-Bartha) tracer in

221 Pseudorabies virus-labelled cells were also seen in the

222 and bladder body injections, the majority of pseudorabies virus-labelled cells were found in the late

223 Very few pseudorabies virus-labelled cells were found rostral to

224 ase of infection in Vero cells infected with pseudorabies virus.

225 c recombinant strains (PRV-152 and BaBlu) of pseudorabies virus.

226 sport of two recombinant isogenic strains of pseudorabies virus.

227 scles, were injected with Bartha's strain of pseudorabies virus.

228 to infer the proximity of several strains of pseudorabies virus.

229 imilar to the phenotype previously shown for pseudorabies virus.

230 o infections by unrelated pathogens, such as pseudorabies virus.

231 ique long region similar to that observed in pseudorabies virus.

232 tructed a panel of Cre recombinase-activated pseudorabies viruses (PRVs) that enabled retrograde trac

233 ell imaging, we made a series of recombinant pseudorabies viruses that encoded green fluorescent prot

234 The large DNA viruses, herpes simplex and pseudorabies viruses, use ubiquitous nectins 1 and 2.