ライフサイエンスコーパス: pseudorabies virus

1 ase of infection in Vero cells infected with pseudorabies virus.

2 c recombinant strains (PRV-152 and BaBlu) of pseudorabies virus.

3 sport of two recombinant isogenic strains of pseudorabies virus.

4 scles, were injected with Bartha's strain of pseudorabies virus.

5 to infer the proximity of several strains of pseudorabies virus.

6 imilar to the phenotype previously shown for pseudorabies virus.

7 o infections by unrelated pathogens, such as pseudorabies virus.

8 ique long region similar to that observed in pseudorabies virus.

9 g after inoculation of the stomach wall with pseudorabies virus 152, a viral label that reports enhan

10 rebral injections of an attenuated strain of pseudorabies virus, a neurotropic alpha herpesvirus that

11 s in the spinal cord, was characterized with pseudorabies virus, a retrograde transynaptic tracer.

12 Using pseudorabies virus, a transsynaptic tracer, in anestheti

13 e poliovirus, herpesvirus, rabies virus, and pseudorabies virus all utilize neuronal retrograde trans

14 Pseudorabies virus, an alpha-herpesvirus, is capable of

15 tructure of the N-terminal half of UL37 from pseudorabies virus, an alphaherpesvirus closely related

16 following infection with the closely related pseudorabies virus and observed similar perimeters of gl

17 ynaptically labeled from the distal colon by pseudorabies virus and several of these were also retrog

18 a subunit, Fluoro-Gold, the Bartha strain of pseudorabies virus, and biotinylated dextran amine.

19 simplex virus types 1 and 2 (HSV-1 and -2), pseudorabies virus, and bovine herpesvirus 1.

20 phaherpesviruses herpes simplex virus (HSV), pseudorabies virus, and bovine herpesvirus type 1.

21 ctures of gH/gL from herpes simplex virus 2, pseudorabies virus, and Epstein-Barr virus revealed dist

22 Cytomegalovirus, pseudorabies virus, and Sindbis virus all evoked a 2-log

23 ilar mutant of the related alphaherpesvirus, pseudorabies virus, and suggests that the glycoprotein r

24 lycoproteins of herpes simplex virus type 1, pseudorabies virus, and varicella-zoster virus, BHV-1 gI

25 fork movement in vivo during replication of pseudorabies virus, another herpesvirus.

26 The glycoproteins I and E of pseudorabies virus are important mediators of cell-to-ce

27 s simplex virus, varicella zoster virus, and pseudorabies virus are neurotropic pathogens of the Alph

28 Using pseudorabies virus as a model, we infected neuron cell b

29 In this report, we have used pseudorabies virus as a neuroanatomical tract tracer in

30 ame animals by injection of a recombinant of pseudorabies virus Bartha (PRV) into the contralateral v

31 he transsynaptic retrograde transport of the pseudorabies virus Bartha (PRV-Bartha) strain has become

32 Pseudorabies virus, Bartha's K strain, was injected into

33 ry associated with the hippocampus using the pseudorabies virus-Bartha strain (PRV-Bartha) tracer in

34 virus 1 (EHV-1), varicella-zoster virus, and pseudorabies virus, but very little is known about the p

35 labeling of the phrenic motoneuron pool with pseudorabies virus demonstrated a substantial number of

36 Pseudorabies virus encodes a membrane protein (Us9) that

37 By using pseudorabies virus expressing green fluorescence protein

38 rions, epithelial cells infected by HSV-1 or pseudorabies virus following ADS express fewer than two

39 milarities and differences between HSV-1 and pseudorabies virus gE.

40 icial chromosome (BAC) containing the 142-kb pseudorabies virus genome was constructed such that the

41 d using green fluorescent protein expressing pseudorabies virus (GFP-PRV) to (1) characterize age-dep

42 sons with homologous HSV-2 gH/gL and partial pseudorabies virus gH structures support the domain boun

43 Recently, a pseudorabies virus glycoprotein D (gD)-green fluorescent

44 The Bartha strain of pseudorabies virus has several recognized mutations, inc

45 naptic labeling from the adrenal gland using pseudorabies virus identified presympathetic GABAergic n

46 ficking, we analyzed the axonal transport of pseudorabies virus in the presence and absence of pUS9.

47 tween HSV1 and the related alphaherpesvirus, pseudorabies virus, in which the homologues of all three

48 al afferent pathways can be identified after pseudorabies virus infection of the kidney.

49 sitive neurones in the LH were labelled with pseudorabies virus injected into the liver of parasympat

50 erebral cortex were identified in rats after pseudorabies virus injections were made in functionally

51 Pseudorabies virus inoculated into the distal femoral me

52 Injection of pseudorabies virus into different regions of the MD or r

53 nsneuronally infected following injection of pseudorabies virus into rectus abdominis or transversus

54 injected the retrograde transynaptic tracer pseudorabies virus into single tensor tympani (TT) muscl

55 Injection of conditional pseudorabies virus into the brain of an LHRH::CRE mouse

56 injected a retrograde-specific strain of the pseudorabies virus into the rat OB and piriform cortex.

57 Fluorogold or green fluorescent pseudorabies virus labeled postganglionic neurons in the

58 We used transsynaptic anterograde pseudorabies virus labeling of fungiform taste papillae

59 The stability of interneuronal pseudorabies virus labeling patterns following lateral c

60 Pseudorabies virus-labelled cells were also seen in the

61 and bladder body injections, the majority of pseudorabies virus-labelled cells were found in the late

62 Very few pseudorabies virus-labelled cells were found rostral to

63 resembles in many respects the phenotype of pseudorabies virus lacking glycoproteins gM, gE, and gI.

64 Mutant pseudorabies virus lacking U(L)3.5 is deficient in viral

65 demonstrate that the pUL31 component of the pseudorabies virus nuclear egress complex is a condition

66 remotor interneurons with the trans-synaptic pseudorabies virus PRV-152 revealed the presence of burs

67 A strain of pseudorabies virus (PRV 152) isogenic with the Bartha st

68 itreal injection of the attenuated strain of pseudorabies virus (PRV Bartha) results in transneuronal

69 ntraocular injection of the Bartha strain of pseudorabies virus (PRV Bartha) results in transsynaptic

70 rus (HSV), varicella-zoster virus (VZV), and pseudorabies virus (PRV) all utilize a complex of two gl

71 well as for the animal herpesviruses porcine pseudorabies virus (PRV) and bovine herpesvirus 1 (BHV-1

72 entified by immunohistochemical detection of pseudorabies virus (PRV) and corticotropin-releasing fac

73 are the most widely used method to visualize pseudorabies virus (PRV) and herpes simplex virus (HSV)

74 he gD glycoprotein of the alphaherpesviruses pseudorabies virus (PRV) and herpes simplex virus 2 (HSV

75 Pseudorabies virus (PRV) and herpes simplex virus type 1

76 Both Pseudorabies virus (PRV) and human Herpes simplex virus

77 3 in herpes simplex virus type 1 (HSV-1) and pseudorabies virus (PRV) and ORF66 in varicella-zoster v

78 ane proteins encoded by the alphaherpesvirus pseudorabies virus (PRV) are internalized after reaching

79 The membrane proteins gI and gE of Pseudorabies virus (PRV) are required for viral invasion

80 The structure of pseudorabies virus (PRV) capsids isolated from the nucle

81 The alphaherpesvirus pseudorabies virus (PrV) establishes latency primarily i

82 Like other alphaherpesviruses, pseudorabies virus (PrV) exhibits restricted gene expres

83 d PSPMNs by using recombinant strains of the pseudorabies virus (PRV) for trans-synaptic tract tracin

84 d PSPMNs by using recombinant strains of the pseudorabies virus (PRV) for transsynaptic tract-tracing

85 pothesis, we used recombinant strains of the pseudorabies virus (PRV) for transsynaptic tract-tracing

86 rograde transport of an attenuated strain of pseudorabies virus (PRV) from the nucleus accumbens was

87 endent retrograde transneuronal transport of pseudorabies virus (PRV) from the stomach wall.

88 determine the role of internalization of the pseudorabies virus (PRV) gE and gI proteins, we construc

89 The pseudorabies virus (PRV) gE gene encodes a multifunction

90 A full-length clone of the 142-kb pseudorabies virus (PRV) genome was constructed as a sta

91 Pseudorabies virus (PRV) glycoprotein E (gE) is a type I

92 ynaptic tracing with peripheral injection of pseudorabies virus (PRV) has been extensively characteri

93 K in herpes simplex virus type 1 (HSV-1) and pseudorabies virus (PRV) have been well studied.

94 using transneuronal retrograde transport of pseudorabies virus (PRV) in normal animals and in animal

95 ction of the transneuronal retrograde tracer pseudorabies virus (PRV) in rats, we previously localize

96 s, was mapped using the transneuronal tracer pseudorabies virus (PRV) in the ferret.

97 cellular virions and axonal assemblies after pseudorabies virus (PRV) infection of cultured neurons.

98 After pseudorabies virus (PRV) infection of murine L929 cells,

99 the host gene expression profile after acute pseudorabies virus (PRV) infection of the CNS using Affy

100 models of viral egress from neurons by using pseudorabies virus (PRV) infection of the rat retina: do

101 nal spread of herpes simplex virus (HSV) and pseudorabies virus (PRV) infection, a culture system con

102 nduced after herpes simplex virus type 1 and pseudorabies virus (PRV) infections of rat embryonic fib

103 When the swine alphaherpesvirus pseudorabies virus (PRV) infects the rat retina, it repl

104 ed by retrograde trans-synaptic migration of pseudorabies virus (PRV) injected into the adrenal gland

105 Using the retrograde, transsynaptic tracer pseudorabies virus (PRV) injected into the BAT of mice,

106 astric nerves transected, were infected with pseudorabies virus (PRV) injected into the external uret

107 ia the transsynaptic retrograde transport of pseudorabies virus (PRV) injected into the kidneys of ra

108 ted neurons in the preoptic region following pseudorabies virus (PRV) injections into either the supe

109 Pseudorabies virus (PRV) injections were made into the l

110 sneuronal tracing studies using injection of pseudorabies virus (PRV) into either the diaphragm or re

111 studied after injecting the Bartha strain of pseudorabies virus (PRV) into the sciatic nerve to provi

112 epithelial cells, alphaherpesviruses such as pseudorabies virus (PRV) invade axons of peripheral nerv

113 Pseudorabies virus (PRV) is a broad host range, swine al

114 Transneuronal spread of pseudorabies virus (PRV) is a multistep process that req

115 Pseudorabies virus (PRV) is a useful tracer that is retr

116 Pseudorabies virus (PRV) is an alphaherpesvirus related

117 Glycoprotein E (gE) gene of pseudorabies virus (PRV) is conserved among diverse alph

118 Pseudorabies virus (PRV) mutants lacking the Us9 gene ca

119 Retrograde infection by pseudorabies virus (PRV) of neuronal populations neighbo

120 by inoculating the ventral stomach wall with pseudorabies virus (PRV) on postnatal day 1 (P1), P4, or

121 simplex virus (HSV) entry activity, but not pseudorabies virus (PRV) or bovine herpesvirus 1 (BHV-1)

122 d the retrograde transneuronal tracer Bartha-pseudorabies virus (PRV) or the retrograde marker choler

123 ane protein present in the lipid envelope of pseudorabies virus (PRV) particles in a unique tail-anch

124 Toward this end, we generated a novel pseudorabies virus (PrV) recombinant in which a 282-bp r

125 In this report, we describe construction of pseudorabies virus (PRV) recombinants that efficiently e

126 Here, we refine this map using pseudorabies virus (PRV) retrograde tracing, indicating

127 The attenuated pseudorabies virus (PRV) strain Bartha contains several

128 After intraocular injection of the virulent pseudorabies virus (PRV) strain Becker into late-stage c

129 To accomplish this, we have constructed pseudorabies virus (PRV) strains in which viral propagat

130 , but partial deletions generated in HSV and pseudorabies virus (PrV) suggest an additional function

131 ly(A) fraction of the lytic transcriptome of pseudorabies virus (PRV) throughout a 12-hour interval o

132 This study used the transneuronal tracer pseudorabies virus (PRV) to investigate the CNS network

133 ns were identified by immunogold labeling of pseudorabies virus (PRV) transported retrogradely and tr

134 The subcellular distribution of the pseudorabies virus (PRV) UL28 protein was examined by in

135 The pseudorabies virus (PRV) UL54 homologs are important mul

136 We demonstrate here that the pseudorabies virus (PRV) Us2 protein is synthesized earl

137 The pseudorabies virus (PRV) Us3 gene is conserved among the

138 The protein product of the pseudorabies virus (PRV) Us9 gene is a phosphorylated, t

139 Pseudorabies virus (PRV) Us9 is a small, tail-anchored (

140 In this report, we demonstrate that the pseudorabies virus (PRV) Us9 protein is present in infec

141 s simplex virus (HSV) and, as reported here, pseudorabies virus (PRV) utilize the ESCRT apparatus to

142 nal sorting and transport of fully assembled pseudorabies virus (PRV) virions is dependent on the vir

143 e provide an initial characterization of the pseudorabies virus (PRV) VP22 homologue.

144 Pseudorabies virus (PRV) was injected into the pancreas

145 tracing experiments were performed in which pseudorabies virus (PRV) was injected into the stellate

146 riments, the retrograde transneuronal tracer pseudorabies virus (PRV) was microinjected into the CEAm

147 A replication-competent gL-null pseudorabies virus (PrV) was shown to express a gDgH hyb

148 dies, we compared gH of the alphaherpesvirus pseudorabies virus (PrV) with gH of the gammaherpesvirus

149 Pseudorabies virus (PRV), a broad host range alphaherpes

150 Pseudorabies virus (PRV), a member of the Alphaherpesvir

151 Pseudorabies virus (PRV), a neurotropic swine alpha herp

152 brane glycoproteins gE and gI are encoded by pseudorabies virus (PRV), a neurotropic, broad-host-rang

153 lenic function was accomplished by injecting pseudorabies virus (PRV), a retrograde transynaptic trac

154 that the amino-terminal one-third of gC from pseudorabies virus (PRV), a swine herpesvirus, includes

155 Pseudorabies virus (PRV), a swine neurotropic alphaherpe

156 g vesicular stomatitis (VSV), Sindbis virus, pseudorabies virus (PRV), adeno-associated virus (AAV),

157 Using pseudorabies virus (PRV), an alphaherpesvirus capable of

158 Pseudorabies virus (PRV), an alphaherpesvirus related to

159 Previous studies showed that proteins from pseudorabies virus (PRV), an alphaherpesvirus, localize

160 erpes simplex viruses (HSV) 1 and 2, porcine pseudorabies virus (PRV), and bovine herpesvirus 1 (BHV-

161 (BHV-1), equine herpesvirus type 1 (EHV-1), pseudorabies virus (PRV), and varicella-zoster virus (VZ

162 pesviruses, such as herpes simplex virus and pseudorabies virus (PRV), are neuroinvasive dsDNA viruse

163 U(S)11c119.3 cells are fully susceptible to pseudorabies virus (PRV), as shown by single-step growth

164 The related animal herpesvirus, pseudorabies virus (PRV), encodes a homologous set of gl

165 sviruses, herpes simplex virus 1 (HSV-1) and pseudorabies virus (PRV), have suggested that UL37 plays

166 pes viruses: herpes simplex virus (HSV1) and pseudorabies virus (PrV), human immunodeficiency virus t

167 peroxidase conjugated to colloidal gold, or pseudorabies virus (PRV), into the nuclear core of the r

168 In the swine pathogen pseudorabies virus (PRV), mutant viruses with internal d

169 Alphaherpesviruses, including pseudorabies virus (PRV), spread directionally within th

170 Live attenuated vaccine strains of pseudorabies virus (PRV), such as PRV Bartha, are among

171 lex virus 1 (HSV-1), HSV-2, and veterinarian pseudorabies virus (PRV), that infect the peripheral ner

172 In pseudorabies virus (PRV), the Us9 protein is a 98-amino-

173 ished retrograde transneuronal viral tracer, pseudorabies virus (PRV), was injected into the ventral

174 The transneuronal tracer, pseudorabies virus (PRV), was used to identify pathways

175 Using a viral transneuronal tract tracer, pseudorabies virus (PRV), we also tested whether the com

176 Using pseudorabies virus (PRV), we have previously shown that

177 Using the neuroinvasive herpesvirus, pseudorabies virus (PRV), we show that the viral protein

178 cle-specific injection of an mRFP-expressing pseudorabies virus (PRV), which acts as a transsynaptic

179 Pseudorabies virus (PRV)-a retrograde transneuronal trac

180 s study were to identify the mechanism(s) of pseudorabies virus (PrV)-induced down-regulation of porc

181 nervous system, alphaherpesviruses-including pseudorabies virus (PRV)-use retrograde axonal transport

182 tion with virulent and attenuated strains of pseudorabies virus (PRV).

183 athways in rats using recombinant strains of pseudorabies virus (PRV).

184 te entry of herpes simplex viruses (HSV) and pseudorabies virus (PRV).

185 of gD (for example, HSV-1/Rid), and porcine pseudorabies virus (PRV).

186 following infection of the left kidney with pseudorabies virus (PRV).

187 a receptor for the porcine alphaherpesvirus pseudorabies virus (PRV).

188 el to study neuronal spread and virulence of pseudorabies virus (PRV).

189 -1), HSV-2, and the related alphaherpesvirus pseudorabies virus (PRV).

190 an alpha-herpes virus, the Bartha strain of pseudorabies virus (PRV).

191 DMV neurons projecting to the stomach using pseudorabies virus (PRV).

192 DA), and retrograde tracing with fluorescent pseudorabies virus (PRV).

193 onserved in varicella-zoster virus (VZV) and pseudorabies virus (PRV).

194 of two neurotropic herpesviruses: HSV-1 and pseudorabies virus (PRV).

195 emale Sprague-Dawley rats were infected with pseudorabies virus (PRV, Bartha's K-strain) by injection

196 nstructing a replication-competent strain of pseudorabies virus (PRV-263) that changes the profile of

197 train of the retrograde transneuronal tracer pseudorabies virus (PRV-Ba) was injected into rat choroi

198 e transneuronal tracer, the Bartha strain of pseudorabies virus (PRV-Ba), were injected into the uppe

199 tract tracing using an attenuated strain of pseudorabies virus (PRV-Bartha) was combined with immuno

200 ions of the SCN using the swine herpesvirus (pseudorabies virus, PRV) as a tool for transynaptic anal

201 S-specific transneuronal viral tract tracer, pseudorabies virus (PRV152) and demonstrated the sensory

202 , to identify GG premotoneurons, we injected pseudorabies virus (PRV152) into the GG muscle.

203 ed fluorophore expression from a recombinant pseudorabies virus (PRV263) carrying a Brainbow cassette

204 tructed a panel of Cre recombinase-activated pseudorabies viruses (PRVs) that enabled retrograde trac

205 Specifically, we injected the conditional pseudorabies virus recombinant (BA2001) that can replica

206 Dual-labeling studies with pseudorabies virus recombinants also showed prephrenic i

207 The first method uses HSV-1 and pseudorabies virus recombinants that express one of thre

208 ransneuronal retrograde pathway tracing with pseudorabies virus revealed connectivity between MnPO VG

209 We constructed a pseudorabies virus strain that expressed Us9-GFP and tes

210 liver and epididymal white fat in mice using pseudorabies virus strains expressing different reporter

211 Two immunohistochemically distinct pseudorabies virus strains were injected into male Sprag

212 riments with ICP4 homologs revealed that the pseudorabies virus TAD is a potent activator of the gD p

213 Despite being a major component of the pseudorabies virus tegument, VP22 is not required for PR

214 We report the development of a pseudorabies virus that can be used for retrograde traci

215 Starting with derivatives of pseudorabies virus that encode a fluorescent protein fus

216 ell imaging, we made a series of recombinant pseudorabies viruses that encoded green fluorescent prot

217 Here, the spread of pseudorabies virus through renal sensory pathways was ex

218 vulgaris leucoagglutinin (anterograde), and pseudorabies virus (transneuronal retrograde) tract-trac

219 n subunit b retrograde tracing from rRPa and pseudorabies virus transynaptic retrograde tracing from

220 The large DNA viruses, herpes simplex and pseudorabies viruses, use ubiquitous nectins 1 and 2.

221 The resistance to pseudorabies virus was CD4(+) T cell dependent, because

222 Pseudorabies virus was injected into the wall of the ven

223 pathway, a retrograde transsynaptic tracer (pseudorabies virus) was injected into the orbicularis oc

224 r the retrograde transneuronal viral tracer, pseudorabies virus, was injected into the stellate sympa

225 an infectious clone of the alphaherpesvirus pseudorabies virus, we have made a collection of truncat

226 ntral nervous system neurons infected with a pseudorabies virus were examined in vitro by using whole

227 /Cas9 and Cre/Lox system against re-emerging Pseudorabies virus, which caused the recent devastating