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1 had a minimal inhibitory effect on the E2-G pseudotype.
2 of infection based on envelope glycoprotein pseudotypes.
3 oncentration (IC(50)) of 1.6 nM against LASV pseudotypes.
4 against vesicular stomatitis virus (VSV)-HCV pseudotype, 15 of 36 serum samples tested had a neutrali
5 ctions of recombinant adeno-associated virus pseudotype 2/5 to overexpress wildtype human alpha-synuc
6 nd self-complementary adeno-associated virus pseudotype 2/9 (AAV2/9) to transduce the nervous system
7 ing a human immunodeficiency virus (HIV)/HCV pseudotype, a VSV/HCV pseudotype, and cell culture-grown
9 length HIV-1(YU2)/vesicular stomatitis viral pseudotype and injected into basal ganglia of syngeneic
10 ng antibodies against infection by divergent pseudotyped and live MERS-CoV strains, as well as antibo
11 highest-affinity MAb, m336, neutralized both pseudotyped and live MERS-CoV with exceptional potency,
14 ainst human immunodeficiency virus (HIV)-HCV pseudotype, and 10 of 36 serum samples tested had a neut
16 hibited IC(50) values of less than 5 nM in a pseudotyped antiviral assay, and compound 13k was demons
19 airs to NAb in donor plasma by using a virus pseudotyping assay, thereby providing an ideal setting t
20 sion vector for ex vivo cell-cell fusion and pseudotype assays demonstrated fusogenicity on a large p
21 iated cleavage and thus inhibit the entry of pseudotypes bearing the glycoprotein derived from SARS-C
22 coprotein pseudotyped viruses but not by the pseudotypes bearing the glycoprotein of vesicular stomat
25 ate infection, in conjunction with smCD4, by pseudotypes carrying Envs from multiple SIVsmm subtypes.
26 iated robust entry into transfected cells by pseudotypes carrying SIVagmSab92018ivTF Env, with lower-
27 infected mice specifically neutralized these pseudotypes; cell transduction was also sensitive to cha
28 , in contrast to VSV-G, mature BASV-G in VSV pseudotypes consists of a mixture of high-mannose and co
31 ftable C17.2 neural stem cells engineered to pseudotype, disseminate, and trans-complement neurovirul
32 ette can be packaged in different AAV capsid pseudotypes, each having a unique transduction profile.
36 ecombinant vesicular stomatitis virus (rVSV) pseudotypes expressing Ebolavirus glycoproteins (GPs) in
37 of marker genes; control of synaptic spread; pseudotyping for infection of selected cells; addition o
39 protein (BASV-G) can be successfully used to pseudotype glycoprotein-deficient vesicular stomatitis v
40 nutoides cells are also infectible with LacZ pseudotypes having AKV Env and Moloney MLV (MoMLV) Gag p
41 o establish infection we used HCV lentiviral pseudotypes (HCVpp) and demonstrated a defect in cell en
42 ither human immunodeficiency virus (HIV)-HCV pseudotypes (HCVpp) nor HIV and Dengue virus (DENV) infe
43 fection mediated by the HeV glycoproteins in pseudotyped-HeV entry assays more effectively than the c
45 ect on human immunodeficiency virus (HIV) GP pseudotyped HIV or adeno-associated virus 2 vector entry
48 HIV-1 or murine leukemia virus Env (MLV-Env)-pseudotyped HIV-1 particles was enhanced in IFN-alpha-tr
49 or expression, as vesicular stomatitis virus-pseudotyped HIV-1 replication was also blocked by IL-12/
50 pan-neutralization against a panel of 56 Env-pseudotyped HIV-1 representing diverse subtypes of clini
53 ansfection production of a Sendai virus F/HN-pseudotyped HIV-1-based third generation lentiviral vect
58 nfirmed that Tat expression and infection of pseudotyped HIV.GFP led to increased lysosomal exocytosi
59 onnative viral particles in a process termed pseudotyping; however, the molecular mechanisms governin
61 h amplification on complementing cell lines, pseudotyping if desired, purification by ultracentrifuga
62 but exhibited no antiviral activity against pseudotypes incorporating either the GP from the LASV-re
64 in a SARS coronavirus (CoV) and Ebola virus-pseudotype infection assay with the oxocarbazate but not
66 astoid cell line (Raji), a poor host for HCV pseudotype infection, exhibited a four- to sixfold enhan
67 iral activity of these compounds in an Ebola pseudotyped infection model was in the low micromolar ra
68 ded compounds with subnanomolar potency in a pseudotype infectivity assay and good pharmacokinetic pr
69 of vesicular stomatitis virus (VSV)/HCV E1-G pseudotype infectivity by antibodies to apolipoprotein E
70 n apolipoprotein B (ApoB), with VSV/HCV E2-G pseudotype infectivity remaining largely unaffected.
73 nerate highly concentrated lentiviral vector pseudotypes involving different envelope glycoproteins.
74 ctivity to vesicular stomatitis virus or HCV pseudotype is generated in animals immunized with recomb
78 did not exhibit a comparable high titer upon pseudotyping, it led to a significant increase in distal
81 ular stomatitis virus glycoprotein G (VSV-G)-pseudotyped lentiviral gene therapy vector could also in
82 ly impaired entry of genotype 1a HCV and HCV-pseudotyped lentiviral particles (HCVpp) in Huh-7 cells
84 ified gibbon ape leukemia virus glycoprotein-pseudotyped lentiviral vector infectivity of HSPCs, the
85 ped a novel targeting Sindbis virus envelope pseudotyped lentiviral vector, 2.2ZZ, which acquires spe
87 fuse to resting CD4(+) T cells while HIV Env-pseudotyped lentiviral vectors fused, reverse transcribe
89 as the major entry port of VSV and of VSV-G-pseudotyped lentiviral vectors in human and mouse cells,
92 ral receptor TVB (TVB-NRG1), along with EnvB pseudotyped lentivirus (LV) and rabies virus (RV), to se
93 dy, the VSV-G (vesicular stomatitis virus G) pseudotyped lentivirus is not and allows us to control f
94 ransfer of Nipah virus envelope glycoprotein-pseudotyped lentivirus particles by MDCs were severely a
95 Neonatal intravascular injection of VSV-G pseudotyped lentivirus resulted in almost exclusive tran
101 exhibited a four- to sixfold enhancement of pseudotype-mediated cell death upon incubation with anti
102 These findings indicate the utility of VSVG-pseudotyped MLV for transgenesis of S. mansoni, herald a
104 chistosomula were exposed to virions of VSVG-pseudotyped MLV, after which genomic DNA was extracted f
105 ith the vesicular stomatitis virus (VSV)/HCV pseudotype model that the hypervariable region 1 of the
107 Moreover, serology testing based on BASV-G pseudotype neutralization can be used to uncover the pre
109 eat the different rates of degeneration, two pseudotypes of recombinant adeno-associated virus (AAV)
110 n of mice with an ecotropic virus results in pseudotyping of intact endogenous viruses that have not
113 This process of complementation, known as pseudotyping, often can occur even when the glycoprotein
114 ing cell-culture HCV 1a(H77)/2a chimera, HCV pseudotype particles (HCVpp) H77, and HCVpp HCV-1 after
115 Each HMAb broadly neutralizes retroviral pseudotype particles expressing HCV E1 and E2 glycoprote
116 nd the resistance of other cell types to the pseudotype particles were similar to those observed for
117 ed two MAbs that can strongly neutralize HCV-pseudotyped particles (HCVpp) bearing the envelope glyco
119 ing cells much more efficiently than did HeV pseudotyped particles (HeVpp), and (iii) NiVpp but not H
120 gth NiV-G, resulted in optimal titers of NiV-pseudotyped particles (NiVpp) ( approximately 10(6) IU/m
123 ne leukemia virus (MLV) Env can readily form pseudotyped particles with many retroviruses, suggesting
127 ry suggested a significant reduction in E1-G pseudotype plaque numbers ( approximately 70%) by inhibi
131 rons were susceptible to infection with EnvA-pseudotyped rabies virus in tumor virus A receptor trans
133 oped vesicular stomatitis virus glycoprotein-pseudotyped replication-defective simian immunodeficienc
134 investigated the possibility of "genetically pseudotyping" replication-competent MLV by replacing the
136 inity than that of sHeV-G, (ii) NiV envelope pseudotyped reporter virus (NiVpp) entered ephrinB3-expr
139 nvelopes between PERV-A and PERV-C and using pseudotyped retroviral vectors to map the human cell tro
140 Rabbit anti-GBV-C E2 Abs neutralized HIV-1-pseudotyped retrovirus particles but not HIV-1-pseudotyp
142 g but that OCEV glycoprotein precursor (GPC)-pseudotyped retroviruses poorly entered 53 human cancer
143 y resistant to infection by flaviviruses and pseudotyped retroviruses, but infection can be restored
149 We infused a single dose of a serotype-8-pseudotyped, self-complementary adenovirus-associated vi
152 eviously showed that IFN-gamma expression by pseudotyped SIVs does not alter viral single-cycle infec
153 ls primed with dendritic cells transduced by pseudotyped SIVs expressing high levels of IFN-gamma had
155 roblasts with a vesicular stomatitis virus G-pseudotyped strain of HIV-1 produced similar results, su
156 n antifiloviral screening system, based on a pseudotyping strategy, and its application in the discov
158 dent inhibition of Moloney MLV Env and VSV G pseudotypes, suggesting that the decrease did not involv
160 ur knowledge, this is the first time the VSV pseudotyping system has been successfully extended beyon
162 e using a human immunodeficiency virus-based pseudotyping system to identify specific regions that af
163 affect host cell properties and recombinant pseudotyping systems in which filovirus structural glyco
164 -expressing vesicular stomatitis virus (VSV) pseudotype that contained the NiV fusion (F) and attachm
165 the potential benefits which may arise from pseudotyping the HIV-1 lentiviral vector with its homolo
166 DC-directed specificity is achieved through pseudotyping the vector with an engineered Sindbis virus
167 ses from cDNA, amplification of the viruses, pseudotyping them with EnvA or EnvB and concentration an
168 We suggest that these two regions dictate pseudotyping through interactions with specific lipid en
170 but not FcRIII, also led to an inhibition of pseudotype titer enhancement in an additive manner.
171 in (GP) gene was used to generate lentiviral pseudotypes to identify small-molecule inhibitors of vir
173 ransfer comparable with that of AAV2 using a pseudotype vector (AAV2/5) at a 100-fold lower dose, our
174 ion significantly increased EBOV GP and VSVG pseudotyped vector transduction but had minimal effect o
179 subsequently show the specific detection of pseudotyped vesicular stomatitis virus (VSV) as a model
181 eudotyped retrovirus particles but not HIV-1-pseudotyped vesicular stomatitis virus particles, and E2
182 ermore, expression of HAP2 on the surface of pseudotyped vesicular stomatitis virus results in homoty
186 property, recombinant forms of VSV and VSV-G-pseudotyped viral vectors are being developed for gene t
188 SARS-CoV S, followed by cell-cell fusion and pseudotyped virion infectivity assays, showed a critical
189 ify inhibitors of arenavirus infection using pseudotyped virion particles bearing the glycoproteins (
191 , inhibited SARS-CoV S-mediated entry of the pseudotyped virions in 293T cells expressing a functiona
193 that membrane fusion during the entry of the pseudotyped virions shares common requirements with the
194 idate genes were identified by using EBOV GP pseudotyped virions to transduce human tumor cell lines
195 try for Ebola virus (EBOV) glycoprotein (GP) pseudotyped virions, we used comparative gene analysis t
198 ptides were also effective in inhibiting HeV pseudotype virus entry in a new assay that mimics multic
200 Epitope characterization was performed using pseudotype virus expressing mutagenized rabies glycoprot
207 susceptible to both EboV RBD binding and GP-pseudotyped virus infection than their nonadherent count
210 d single round vescicular stomatitis virus-G pseudotyped virus replication, whereas superinfection of
211 the SF162 virus with the JR-FL V3 created a pseudotyped virus that was hypersensitive to neutralizat
212 uses a lentivirus/vesicular stomatitis virus pseudotyped virus to engineer CD3/CD28-stimulated human
213 R followed by cloning of env genes to create pseudotyped virus to explore the link between genotypic
214 l receptor TVB fused to NRG, along with EnvB-pseudotyped virus, is able to direct infection selective
215 y isolates of subtypes A, B, and C in an Env-pseudotyped-virus neutralization assay, albeit with redu
216 PR15, to a lesser extent, supported entry of pseudotype viruses bearing SIVagm envelopes, including S
218 oprotein (EBOV-GP) gene was used to generate pseudotype viruses for screening of chemical libraries.
220 tically and geographically diverse HIV-1 Env-pseudotyped viruses and chronic infection plasma samples
221 tent neutralization against EBOV and SUDV GP pseudotyped viruses as well as authentic pathogens, and
222 l of reference Env clones from among 219 Env-pseudotyped viruses assayed in TZM-bl cells with sera fr
223 the infection by EBOV and EBOV glycoprotein pseudotyped viruses but not by the pseudotypes bearing t
225 ependent entry of trypsin-treated retrovirus pseudotyped viruses expressing JMD mutant S Delta19 prot
227 he small molecule inhibited the entry of all pseudotyped viruses in vitro and the cleavage of SARS-Co
228 9 was active against 636 different HIV-1 Env-pseudotyped viruses of varying tropism and derived from
229 tibody, 10E8V2.0/iMab, neutralized 118 HIV-1 pseudotyped viruses tested with a mean 50% inhibitory co
230 Studies of entry performed with HTLV-3 Env-pseudotyped viruses together with SU binding studies rev
231 icular stomatitis virus glycoprotein (VSV-G)-pseudotyped viruses were generated by cotransfecting 293
232 from 200 southern African, clade C envelope-pseudotyped viruses with neutralization titers against 1
242 Furthermore, the infection of PHH by the pseudotype was sensitive to known inhibitors of HBV and
243 he entry of human immunodeficiency virus-HCV pseudotypes was significantly inhibited in C75-treated H
244 y high efficiency regardless of the envelope pseudotype while scAAV9 mediates gene delivery to 40% o
245 uld reduce the gene transfer inoculum of the pseudotype while still achieving gene transfer comparabl
248 eover, Ad-5/3-kappaBF512HRE, a viral variant pseudotyped with a chimeric 5/3 fiber, exerted a strong
250 d improved photoreceptor transduction by Ad5 pseudotyped with Ad35 (Ad5/F35) or Ad37 (Ad5/F37) fiber
253 protein (GFP)-expressing proviral construct pseudotyped with CCR5-tropic or CXCR4-tropic envelope to
254 compare the transduction efficiency of IDLVs pseudotyped with different envelopes (vesicular stomatit
259 1b, as well as neutralization of lentivirus pseudotyped with HCV 1a and 1b envelope glycoproteins.
260 from these antibodies, retrovirus particles pseudotyped with HCV glycoproteins (HCVpp) isolated from
261 neutralized a panel of retroviral particles pseudotyped with HCV glycoproteins from six genotypes an
262 and, as negative controls, env-minus viruses pseudotyped with HIV-1, vesicular stomatitis virus, or m
263 ted vesicular stomatitis virus (VSV) virions pseudotyped with HSV-1 essential entry glycoproteins gB,
265 ected cells, inhibited entry of retroviruses pseudotyped with Marburg virus GP(1,2), as well as Marbu
267 ion of human T cells by HIV reporter viruses pseudotyped with R5-tropic gp120 envelope proteins but h
268 of compounds for blocking of entry of HIV-1 pseudotyped with SARS-CoV surface glycoprotein S (SARS-S
273 activity, with mammalian retroviral vectors pseudotyped with the ASLV-A envelope glycoprotein (EnvA)
275 tor signaling, enhanced the entry of viruses pseudotyped with the glycoprotein of lymphocytic choriom
276 cycle simian immunodeficiency viruses (SIVs) pseudotyped with the glycoprotein of vesicular stomatiti
277 s markedly enhanced the infection of viruses pseudotyped with the GP of Machupo, Guanarito and Junin
278 imaged fusion of single retroviral particles pseudotyped with the vesicular stomatitis virus (VSV) G
279 s effect was not observed with HIV-1 virions pseudotyped with the vesicular stomatitis virus glycopro
281 HD5 and HD6 promoted HIV reporter viruses pseudotyped with vesicular stomatitis virus and murine l
283 replication of human immunodeficiency virus pseudotyped with vesicular stomatitis virus G protein an
284 upon infection of mouse DCs with HIV-1 cores pseudotyped with vesicular stomatitis virus G protein.
285 the Moloney murine leukemia retrovirus (MLV) pseudotyped with vesicular stomatitis virus glycoprotein
286 e for HSPC transduction enhancement with LVs pseudotyped with vesicular stomatitis virus glycoprotein
287 lycoprotein S (SARS-S) but not that of HIV-1 pseudotyped with vesicular stomatitis virus surface glyc
289 T cells with lentiviral particles that were pseudotyped with VSV-G or CXCR4-tropic HIV Env and assay
290 an immunodeficiency chimeric virus particles pseudotyped with XMRV envelope protein were used to demo
291 of a green fluorescent protein (GFP) vector pseudotyped with XMRV produced GFP(+) CD4(+) T cells and
293 zation in vitro can be partially bypassed by pseudotyping with Ad45 fiber protein, indicating that a
294 ly developed targeting lentiviral vectors by pseudotyping with modified Sindbis virus envelope protei
295 nd confocal microscopy, we demonstrated that pseudotyping with rabies virus envelope glycoprotein (RV
296 rotrophin receptor), thus demonstrating that pseudotyping with RV-G targets lentiviral vectors for tr
299 , the polytropic MuLV genome was extensively pseudotyped within ecotropic virions; polytropic virus r
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