1 BCC6 gene cause soft-tissue calcification in
pseudoxanthoma elasticum (PXE) and, in some patients, ge
2 Pseudoxanthoma elasticum (PXE) is a classic inherited di
3 Pseudoxanthoma elasticum (PXE) is a heritable disorder c
4 Pseudoxanthoma elasticum (PXE) is a heritable disorder m
5 Pseudoxanthoma elasticum (PXE) is a multisystem disorder
6 Pseudoxanthoma elasticum (PXE) is a multisystem ectopic
7 Pseudoxanthoma elasticum (PXE) is a pleiotropic multisys
8 Pseudoxanthoma elasticum (PXE) is a systemic heritable d
9 Pseudoxanthoma elasticum (PXE) is an autosomal recessive
10 Pseudoxanthoma elasticum (PXE) is an autosomal recessive
11 Pseudoxanthoma elasticum (PXE) is an autosomal recessive
12 Pseudoxanthoma elasticum (PXE) is caused by mutations in
13 Pseudoxanthoma elasticum (PXE) is caused by mutations in
14 Pseudoxanthoma elasticum (PXE) is caused by mutations in
15 The pathologic hallmark of
pseudoxanthoma elasticum (PXE) is ectopic mineralization
16 The classic
pseudoxanthoma elasticum (PXE) phenotype derives from mu
17 rformed linkage analysis on 21 families with
pseudoxanthoma elasticum (PXE) using 10 polymorphic mark
18 cular fundus abnormalities characteristic of
pseudoxanthoma elasticum (PXE) were detected by cSLO in
19 Pseudoxanthoma elasticum (PXE), a multisystem disorder c
20 Pseudoxanthoma elasticum (PXE), a pleiotropic heritable
21 Pseudoxanthoma elasticum (PXE), a pleiotropic multisyste
22 Pseudoxanthoma elasticum (PXE), a prototype of heritable
23 Pseudoxanthoma elasticum (PXE), a prototypic heritable d
24 Pseudoxanthoma elasticum (PXE), a rare genetic disease c
25 Pseudoxanthoma elasticum (PXE), an autosomal recessive d
26 A characteristic feature of classic
pseudoxanthoma elasticum (PXE), an autosomal recessive d
27 Pseudoxanthoma elasticum (PXE), characterized by connect
28 cular fundus abnormalities characteristic of
pseudoxanthoma elasticum (PXE), including peau d'orange,
29 The ABCC6 gene, which is mutated in
pseudoxanthoma elasticum (PXE), resided within a small r
30 Although clinical similar to
pseudoxanthoma elasticum (PXE), the skin changes were fo
31 To better understand the pathogenetics of
pseudoxanthoma elasticum (PXE), we performed a mutationa
32 system have been identified in families with
pseudoxanthoma elasticum (PXE).
33 f all Vanderbilt Eye Institute patients with
pseudoxanthoma elasticum and at least 1 set of color fun
34 This report summarizes the progress in
pseudoxanthoma elasticum and other ectopic mineralizatio
35 els, resulting in the calcification disorder
pseudoxanthoma elasticum and some cases of generalized a
36 nderlie the incurable calcification disorder
pseudoxanthoma elasticum and some cases of generalized a
37 ted a series of Abcc6(-/-) rats as models of
pseudoxanthoma elasticum depicting ectopic mineralizatio
38 Pseudoxanthoma elasticum in humans and dystrophic cardia
39 Pseudoxanthoma elasticum is a multisystem ectopic minera
40 Pseudoxanthoma elasticum is a prototype of heritable ect
41 Pseudoxanthoma elasticum like fundus changes are a frequ
42 mately 200 mutations have been identified in
pseudoxanthoma elasticum patients, the underlying struct
43 rter C6) ABC transporter are associated with
pseudoxanthoma elasticum, a disease of altered elastic p
44 drug efflux pumps, are the genetic basis of
Pseudoxanthoma elasticum, a disease that affects elastin
45 Pseudoxanthoma elasticum, a heritable ectopic mineraliza
46 Mutations in ABCC6 result in
pseudoxanthoma elasticum, a multi-system heritable conne
47 eye (3%) had neovascularization secondary to
pseudoxanthoma elasticum, all showing similar ORT format
48 The prototype of such conditions is
pseudoxanthoma elasticum, and related conditions with ov
49 ic atrophy independent of CNV can develop in
pseudoxanthoma elasticum, causing significant vision los
50 exemplified by familial tumoral calcinosis,
pseudoxanthoma elasticum, generalized arterial calcifica
51 ions in four candidate genes associated with
pseudoxanthoma elasticum, the prototype of ectopic miner
52 In a humanized mouse model of
pseudoxanthoma elasticum, we investigated whether 4-PBA
53 The fundamental question on pathogenesis of
pseudoxanthoma elasticum, whether lack of ABCC6 expressi
54 Pseudoxanthoma elasticum-like changes were more frequent
55 Pseudoxanthoma elasticum-like fundus changes are a frequ
56 several months prevented the development of
pseudoxanthoma elasticum-like spontaneous calcification,
57 tion to counteract ectopic mineralization in
pseudoxanthoma elasticum.
58 efore provides a novel model system to study
pseudoxanthoma elasticum.