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1 psi-Values are zero or unity for all sites except one at
2 ens offset (-5 V), auxiliary gas pressure (0 psi), and isolation width of parent ion (m/z value = 3).
3 As expected, digestion efficiency at 10,000 psi was increased and reproducibly produced more peptic
5 rformed at pressures up to 6900 bar (100,000 psi), consumes a large sample volume and is very irrepro
6 iquid chromatography at approximately 11,000 psi on sub 2-microm particles combined with reversed-pha
8 200 nL and operated at approximately 20,000 psi (1380 bar), the system showed a peak area reproducib
11 L) and operated at pressures close to 30,000 psi (2070 bar), the reproducibility in peak area for the
22 gh pressure [>20 psi], low pressure [5 to 10 psi], or very low pressure [1 to 2 psi]) and one of two
24 re unchanged even to 120 degrees C under 100 psi of O2 and in the presence of active radical chains (
25 ucted by reacting 2(TFE)-(13)C with 300-1000 psi of methane in single-crystal sapphire NMR tubes; cle
29 3 Sprague Dawley adult rats to unilateral 14 psi blast exposure to induce tinnitus and measured audit
32 , a pressure drop of only approximately 1500 psi is sufficient to maintain an effluent flow rate of <
37 eins at pressure gradients of 12 bar/cm (180 psi/cm) has been performed using a microdevice that inte
38 [5 to 10 psi], or very low pressure [1 to 2 psi]) and one of two irrigation solutions (castile soap
40 Similar leaks in carbon steel pipes at 20 psi self-repaired at pH 5.5 and 8.5, but two leaks did n
41 retically or by pressure pulses (10 ms at 20 psi) into the taste-responsive regions of the NST and th
42 ree irrigation pressures (high pressure [>20 psi], low pressure [5 to 10 psi], or very low pressure [
43 iquid-liquid separations run at or above 200 psi to provide solvent-free product, and the use of high
44 m tetraborate solution eluent (typically 200 psi) as the pump, and performing on-column detection usi
45 could withstand internal pressures of >2250 psi, more than 1 order of magnitude higher than their th
47 l pressures above 20 MPa (approximately 2900 psi) for efficient pressure-driven HPLC separations.
49 x between an RNA hairpin derived from the 3' psi pocket of human U65 H/ACA small nucleolar RNA (snoRN
50 discovered that low hydrogen pressures (<30 psi) were essential to achieve high enantioselectivities
51 dized with 0.5 mol % Pd/Au (3:1)-17 under 30 psi of oxygen in water to give the dihydroxylated produc
53 in 78% yield under catalytic conditions (35 psi H(2)), presumably by the 5-exo-trig cyclization of t
54 ed that some of the repairs created at 20-40 psi ambient pressure could withstand more than 100 psi w
55 formation of corrosion precipitates at 20-40 psi, pH 3.0-11.0, and with upward and downward leak orie
56 er exchange under low-pressure operation (40 psi), parameters such as the size exclusion resin, load
59 osed to blast wave pressure of 300 kPa (43.5 psi) per day for 3 successive days, and euthanized 30 da
60 as flow of 6 mL/min, nebulizer pressure of 5 psi, and drying gas temperature set to 200 degrees C.
61 s under mild conditions (35 degrees C and 50 psi CO/H(2)), and Z-olefins afford excellent enantiosele
62 ely low-pressure catalytic hydrogenation (50 psi of hydrogen) was employed using Raney nickel as the
64 ylene pressure was increased from 100 to 500 psi in order to produce semicrystalline ethylene-rich en
65 onic Rh(I)-Josiphos complex in THF under 500 psi of H2 generated the corresponding tertiary carbinami
66 c columns at a mobile-phase pressure of 5000 psi provide flow rates of approximately 40 nL/min at a l
67 ature, 200 degrees C; nebulizing pressure, 6 psi (0.414 bar); capillary voltage, +2.5 kV; fragmentor
68 ated pressures, beyond the conventional 6000 psi (400 bar), has created a demand for injection system
73 is of CRP, including sheath gas pressure (80 psi), capillary temperature (275 degrees C), collision e
74 ation is independent of CO pressure up to 80 psi; above 80 psi one observes the onset of inhibition.
79 nd the specific PKC epsilon peptide agonist, psi epsilonRACK, each activated mitoK(ATP)-dependent K+
80 priming by the selective PKCepsilon agonist, psi epsilon receptor for activated c kinase (psiepsilonR
81 mp loading reaction by two subunits, chi and psi, which are not present in the crystal structures, we
84 as well as those encoding mu-, kappaM-, and psi-conotoxins revealed highly conserved amino acid resi
88 e native structure by changing every phi and psi angle by either +/-3, +/-5 or +/-7 degrees, five sma
92 The mean absolute error (MAE) of phi and psi angles predicted by DRNN, DReRBM, DRBM and DNN is ab
99 xes revealed similar ranges of phi (phi) and psi (psi) angles between iduronate and glucosamine rings
101 pically in mini c TAR DNA, mini TAR RNA, and psi(3) RNA, but at 5 degrees C, the motion became more a
102 rmation in much the same way that varphi and psi are used to describe backbone configuration of prote
104 dependent constraints on backbone varphi and psi torsion angles in samples with sequential pairs of c
105 echanical bonds (corresponding to varphi and psi) that include realistic barriers to rotation that cl
109 ifts are dominated by local torsion angles , psi, chi1; hence, these experiments identify flexible to
113 the ATPase spiral observed upon DNA binding, psi binding promotes the clamp-loading activity of the c
116 r mimic of stem-loop 3 RNA (SL3, also called psi-RNA, in the packaging domain of genomic RNA) is stro
117 The DnaX complex (DnaX(3)deltadelta'chi psi) within the Escherichia coli DNA polymerase III holo
118 two NC-binders to inhibit viruses containing psi-region deletions (DeltaSL1 or DeltaSL3) and found th
119 landscape of psi over which stomata control psi, and (2) the slope of the daily range of psi as pre-
121 bsence of competition with the corresponding psi transcripts lacking SL1 or SL3 for binding DP6-Gag i
122 sslink-values agree with their corresponding psi-values when they have both have values of zero or on
123 -values are smaller than their corresponding psi-values, the apparent underestimation of structure fo
124 dues within the consensus sequence psiKxE/D (psi is a hydrophobic residue and x is any residue), alth
126 slope of the daily range of psi as pre-dawn psi declined, were strongly correlated with each other a
127 ity (7.5-fold, P < 0.02) and decreased delta psi m (2.6-fold, P < 0.04), and had decreased cell viabi
128 hat before autophagy mitochondria lose delta psi(m) and OPA1, and that overexpression of OPA1 decreas
129 -2 antagonist, rapidly induced loss of Delta psi m and caspase-9 activation but had no effect on the
130 mitochondrial transmembrane potential (Delta psi m) and weak caspase-9 activation, whereas thapsigarg
132 xhibited increased membrane potential (delta psi(m)) and a high probability of subsequent fusion, whi
133 ondria that were found to have reduced delta psi(m) and decreased levels of the fusion protein OPA1.
136 od of estimation of the parent distribution, psi(D)(f), based on analyzing the force data for a tande
140 t our results in a simple correction factor, psi, the ratio of the corrected Young's modulus and the
142 ative-like, respectively, while a fractional psi implies that in the TSE, the biHis site recovers onl
144 acent to a site with psi = 1, the fractional psi generally signifies that the "fractional site" has a
146 counted for by the proportion of prion-free [psi(-) ] cells present, no change in the molecular weigh
149 ntaining the isostere, Ac-(Gly-Pro-Hyp)3-Gly-psi[(E)CH C]-Pro-Hyp-(Gly-Pro-Hyp)4-Gly-Gly-Tyr-NH2, had
155 used bioinformatics applications, including (psi)-blast, modeller, muscle and Primer3, and tools are
156 The inability of these aptamers to inhibit psi-deleted viruses correlated with the absence of compe
159 d solute accumulation of ahk1 mutants at low psi(w) suggest that AHK1 may not be the main plant osmos
168 mp partially compensates for the activity of psi when this subunit is not present and possibly serves
169 esults demonstrate the unique application of psi-value analysis in elucidating the structure of the t
171 allenging protein, we apply a combination of psi analysis (which probes the role of specific side-cha
172 metrics of stringency of stomatal control of psi, (1) a 'hydroscape' incorporating the landscape of p
174 pment of ligands that target the elements of psi-RNA of HIV-1 with high affinity and specificity.
175 chanistic investigation to another family of psi synthases and an enzyme that makes an adduct with f5
176 'hydroscape' incorporating the landscape of psi over which stomata control psi, and (2) the slope of
177 able to the existing methods, but the MAE of psi angle is 29 degrees , 2 degrees lower than the exist
180 psi, and (2) the slope of the daily range of psi as pre-dawn psi declined, were strongly correlated w
182 rics of stringency of stomatal regulation of psi during soil drying in eight woody species and determ
183 s in src SH3, are compared to the results of psi-analysis where strand association is stabilized by m
184 appear to be the highest combined values of psi and phi (34.3 degrees and 33.5 degrees, respectively
189 alpha) atoms (residues 5-28) is 0.3 A; (phi, psi) angles of D-Ala20 are the same as those of G20 in t
190 is of the Ramachandran dihedral angles (phi, psi) reveals that the residues adopting disallowed confo
191 amino acids by comparing their backbone phi, psi distributions in different types of secondary struct
194 isotropic chemical shifts and backbone (phi, psi) torsion angles indicate that both TPF4 and TPA4 ado
195 of the activation segment, measured by phi, psi, chi1, and pseudo-dihedral angles more accurately cl
196 and binding shows that the magnitude of phi, psi changes are in general minimal, although some large
198 xperiments, we are able to predict the (phi, psi, chi(1)) angles of Ala and Val within 5.8 degrees of
199 ,916 conformations as a function of the phi, psi, omega, chi1 and chi2 torsional angles for all 20 na
200 nor an ideal beta-hairpin with uniform (phi, psi) angles and coplanar strands, agrees with the experi
201 istributions around the average values (phi, psi) approximately (-57 degrees , -31 degrees) with a wi
202 ure of KL 4 when bound to lipids, with (phi, psi) angles that differ substantially from common values
203 There are no obvious correlations with phi, psi, chi 1, or chi2 torsion angles, unlike the results s
205 h we call the niche, with characteristic phi,psi angles, is by far the commonest feature with this pr
206 y an initial exploration of the complex (phi,psi)(2) landscape of proteins, it shows that there is va
207 anosyloxy)-3',4'-didehydro-1',2'-dihydro-phi,psi-caroten -2'-ol, is novel and has been given the triv
210 resolution or better to create a purely phi,psi-based comprehensive empirical categorization of comm
211 nally rapid algorithm using only single (phi,psi) dihedral angle moves also generates tertiary struct
212 ted level of precision in describing the phi,psi angles of both previously known and novel motifs, or
214 four-dimensional space based on the two phi,psi pairs to yield a parameter-dependent list of (phi,ps
216 f the fragment to a database of multiple phi-psi angles from high-resolution x-ray crystal structures
217 t is scored based on the fit of multiple phi-psi angles of the fragment to a database of multiple phi
222 ns arising from fluctuations in backbone phi/psi torsion angles in the picosecond to nanosecond regim
223 ithms for chemical fragments, 3D motifs, phi/psi sequences, super-secondary structure motifs and for
227 approximately -60 degrees) and more positive psi (> or = 160 degrees) give spectra showing the P(II)
231 uence similarity to enzymes known to produce psi-end group modifications of carotenoids in proteobact
232 osed TCV hairpins H4a and H4b and pseudoknot psi(3), which are required for the TCV-specific requirem
234 t position 34 (mcm5s2U34) and pseudouridine (psi) at position 39--two of which, ms2t6A37 and mcm5s2U3
236 a phylogenetically conserved pseudouridine (psi) residue in the segment of U2 snRNA that pairs with
237 ses) isomerize uridine (U) to pseudouridine (psi) in RNA, and they fall into five families that share
238 RNA contains at least one pseudouridylation (psi) pocket, which is complementary to the sequences fla
239 evealed similar ranges of phi (phi) and psi (psi) angles between iduronate and glucosamine rings.
240 ct of Xer recombination at directly repeated psi sites on a circular unknotted DNA molecule is a righ
242 genomic RNA with an intact packaging signal (psi) and Gag were observed to extend outward from the cy
245 e CRISPR loci (termed prokaryotic silencing (psi)RNAs) and the RAMP module (or Cmr) Cas proteins.
247 amino ester trifluoromethyl aldimines, small psi[CH(CF3)NH]-peptidomimetic backbones can be achieved
248 on for the dominant-negative effects of such psi-no-more (PNM) mutations and demonstrate directly the
250 se III holoenzyme depends upon a Pol III-tau-psi-chi-SSB binding network, where SSB is bound to the d
255 hi angle of the ith residue (phi(i)) and the psi angle of the residue i - 1 (psi(i-1)) on the 0.1 ps
256 ential interaction between HIV-1 Gag and the psi-region that may be distinct from that which occurs d
261 e genes encoding two enzymes that modify the psi end of myxoxanthophyll in Synechococcus sp. strain P
262 sequence (pal) located at the 3' end of the psi encapsidation signal is critical for human immunodef
265 be asymmetric and strongly dependent on the psi backbone angle before and after phosphorylation.
267 rticle, we show structural evidence that the psi pocket can form the predicted base pairs with substr
268 ts from our work and others suggest that the psi subunit may introduce a temporal order to the clamp
270 tial energy profile generated by varying the psi dihedral angle in Ace-Pro-NMe indicates that the con
274 agonist (DAMGO) and deltaOR antagonist (Tipp(psi)), and this leads to a shift in the pattern of ERK1/
275 tem, the Xer accessory protein PepA binds to psi accessory sequences, interwraps them, and brings the
276 capsid domain of Gag preferentially binds to psi and Rev Response elements in the viral genome, and G
277 This method is adapted from the traditional psi-value analysis, which uses engineered bi-His metal c
279 e other globular protein characterized using psi-analysis, also exhibits a single consensus TSE struc
280 l phosphatase (ctAcP) is characterized using psi-analysis, which identifies specific chain-chain cont
282 ribution of backbone dihedral angles (varphi,psi) obtained from an experimentally validated denatured
284 minates another substantial region of varphi,psi-space for a blocked peptide; for conformers within t
285 steric clashes alone eliminate 3/4 of varphi,psi-space, a result that has guided all subsequent work.
290 ded proteins arising due to intrinsic varphi-psi dihedral angle fluctuations dictate the course of pr
291 he backbone torsional mobility in the varphi-psi dihedral angle space, we used a model intrinsically
293 tropy in folded proteins by using the varphi-psi distributions of the 20 amino acids in common second
294 h are all down (Cgamma-endo), and the varphi/psi dihedral angles of the Xaa 3(S)Hyp residues are also
295 on of U0126 delivered at ischemia onset with psi deltaRACK injected at reperfusion increased infarct
296 fractional psi lies adjacent to a site with psi = 1, the fractional psi generally signifies that the
297 fractional site is distal to the sites with psi = 1, however, the histidines sample configurations i
299 -Gly dipeptide surrogates in the form of Xaa-psi[triazole]-F2Gly building blocks were established, an
300 cent to the accessory sequences from the Xer/psi multimer resolution system, we have imposed topologi
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