ライフサイエンスコーパス: psychopathology

1 n moderates the impact of stress on risk for psychopathology.

2 ght predispose individuals to stress-related psychopathology.

3 hood may be understood as prodromal to adult psychopathology.

4 ction that often mirror patterns observed in psychopathology.

5 h decreased school performance and increased psychopathology.

6 r between groups and was not associated with psychopathology.

7 s, a phenotype associated with resilience to psychopathology.

8 havioral, and cognitive problems, as well as psychopathology.

9 or understanding mechanisms underlying human psychopathology.

10 h indicators, including obesity, injury, and psychopathology.

11 ng-state functional connectivity (rs-FC) and psychopathology.

12 d function, which, in turn, confers risk for psychopathology.

13 compared to other non-compulsive aspects of psychopathology.

14 d reduced binge-eating frequency and related psychopathology.

15 were associated with specific dimensions of psychopathology.

16 e windows of vulnerability and resilience to psychopathology.

17 lter the trajectory of risk in developmental psychopathology.

18 jectory and predispose to or protect against psychopathology.

19 y (TLE) patients with a history of affective psychopathology.

20 y debilitating, conferring risk for lifelong psychopathology.

21 e strongest risk factors for later emotional psychopathology.

22 rly life environmental factors in later life psychopathology.

23 a novel biomarker for the early detection of psychopathology.

24 the childhood risk to develop stress-related psychopathology.

25 onin transporter function and stress-related psychopathology.

26 l risk for depression) or with no history of psychopathology.

27 gdala function in relation to stress-related psychopathology.

28 flammation is associated with stress-related psychopathology.

29 od as manifestations of latent dimensions of psychopathology.

30 ntially defines resilience as the absence of psychopathology.

31 underlie the parent-to-child transmission of psychopathology.

32 d by studies, and poor control of coexisting psychopathology.

33 useful in translation to human behavior and psychopathology.

34 ory of unconscious motivational processes to psychopathology.

35 t can potentially lead to the development of psychopathology.

36 nism for how maltreatment increases risk for psychopathology.

37 n interview-based measures of trauma-related psychopathology.

38 Childhood abuse is a major risk factor for psychopathology.

39 ral symptoms) plus a general factor: overall psychopathology.

40 and preventing them from developing further psychopathology.

41 (impulsivity and overcontrol) contribute to psychopathology.

42 is in part heritable and often disrupted in psychopathology.

43 Y signaling might reduce the risk to develop psychopathology.

44 domains of psychological function linked to psychopathology.

45 viating eating disorder features and general psychopathology.

46 tributes to the chronicity of trauma-related psychopathology.

47 of cognitive dimensions, brain activity, and psychopathology.

48 l therapeutic application for stress-related psychopathology.

49 to perturbed sleep-wake cycles comorbid with psychopathology.

50 elevations in symptoms of multiple forms of psychopathology.

51 debilitating, and it often leads to further psychopathology.

52 nd might confer resilience to stress-related psychopathology.

53 nse of emotional brain circuits and risk for psychopathology.

54 ma-exposed adults with severe trauma-related psychopathology.

55 sights into vulnerability for stress-related psychopathology.

56 d the influence of type of hearing device on psychopathology.

57 echanism-based treatments for trauma-related psychopathology.

58 erties of the MNS, and on social context and psychopathology.

59 ate and objective quantitative estimation of psychopathology.

60 l-being likewise predicts the risk for later psychopathology.

61 rain-behavior relationships in children with psychopathology.

62 fer risk for internalizing and externalizing psychopathology.

63 ss a population of adults with heterogeneous psychopathology.

64 rauma is translated into biological risk for psychopathology.

65 iation is a complex, ubiquitous construct in psychopathology.

66 d not differ significantly on any measure of psychopathology.

67 differences in behavior as well as risk for psychopathology.

68 Childhood trauma is a key risk factor for psychopathology.

69 lammatory links between childhood trauma and psychopathology.

70 etal growth also predicts the risk for later psychopathology.

71 sequent stressors, and, ultimately, risk for psychopathology.

72 e cognition are vulnerable to broad-spectrum psychopathology.

73 biological marker across different types of psychopathology.

74 extrastriatal areas and predicts subclinical psychopathology.

75 d imbalance in this system may contribute to psychopathology.

76 implicated in decision making, learning, and psychopathology.

77 ute a key candidate mechanism for depressive psychopathology.

78 sms related to higher cognitive circuits and psychopathology.

79 ich trauma exposure might influence risk for psychopathology.

80 malities are linked to schizophrenia-related psychopathology.

81 was correlated with measures of anxiety and psychopathology.

82 l yet understudied symptom of trauma-related psychopathology.

83 genetic and environmental associations with psychopathology.

84 e Ce, has a role in stress, and is linked to psychopathology.

85 useful in translation to human behavior and psychopathology.

86 early-life experience, parental stress, and psychopathology.

87 as gender, personality traits, and degree of psychopathology.

88 disorder that has a limited effect on adult psychopathology.

89 acial actions and a loss of this capacity in psychopathologies.

90 ipants who experience loneliness and in many psychopathologies.

91 ss or trauma, to increased susceptibility to psychopathologies.

92 PACAP expression and signaling may result in psychopathologies.

93 ibility, and heterogeneity of stress-related psychopathologies.

94 eeking habits, a putative factor in multiple psychopathologies.

95 al health, and its dysregulation may lead to psychopathologies.

96 or and may predispose individuals to various psychopathologies.

97 r behavioural traits such as personality and psychopathology (~0.10) or physical traits such as heigh

98 ntify RDoC constructs driving the syndrome's psychopathology; (2) create a structured intervention ut

99 of MBD5 disruptions and the associated human psychopathology, 22 individuals with genomic disruption

100 ces, (2) motivation and decision making, (3) psychopathology, (4) social resources, (5) ethical and l

101 silience differs from quantitatively defined psychopathology according to the authors' definition.

102 Evaluations assessed hypochondriasis, other psychopathology, adverse events, functional status, and

103 significant group differences in severity of psychopathology after 12 weeks of treatment.

104 cy of early intervention in preventing adult psychopathology among high-risk early-starting conduct-p

105 eater risk for development of stress-related psychopathology among individuals who experienced the ad

106 a novel target mechanism for stress-related psychopathologies and neurodegeneration.

107 gree relatives (49 relatives had no lifetime psychopathology and 25 had a non-BD mood disorder), and

108 Patients were evaluated for psychopathology and all participants completed neuropsyc

109 nction and may thus contribute to borderline psychopathology and even open new avenues for targeted p

110 he secondary outcomes were general levels of psychopathology and functioning, as assessed by the Brie

111 hology, functioning, treatment, and familial psychopathology and functioning.

112 ror has contributed to the impoverishment of psychopathology and has affected our research, clinical

113 tasks is present early in the development of psychopathology and herein could not be attributed to ch

114 Psychopathology and imaging data were available for 1538

115 icacy of early intervention to prevent adult psychopathology and improve well-being in early-starting

116 ts, the exact occurrence of various forms of psychopathology and its causes are unclear, while this k

117 Both specialists in cognitive psychopathology and neurobiologists have proposed explan

118 g variables (underlying links between parent psychopathology and offspring outcomes) and possible mod

119 d genetic factors in the development of both psychopathology and optimal wellbeing that holds long-te

120 ntal risk reflects features of both parental psychopathology and other aspects of the rearing environ

121 sposing to the development of trauma-related psychopathology and provide biologically plausible suppo

122 resulting neurodevelopmental and behavioral psychopathology and provides clinical context for interp

123 nfluence in women with AN on eating disorder psychopathology and psychological distress has not previ

124 Eating disorder psychopathology and psychological distress were assessed

125 enotypes to the development of internalizing psychopathology and set the stage for developing improve

126 replicate prior work on telomere length and psychopathology and show that this effect is not seconda

127 tively associated with all examined forms of psychopathology and substance use disorders, latent vari

128 more accurately model the dynamic nature of psychopathology and system change as well as have treatm

129 stood that disturbing memories contribute to psychopathology and that new emotional experiences contr

130 r pattern is seen in individuals at risk for psychopathology and whether this can be modified by phar

131 Pessoa (2013) can be successfully applied to psychopathology and, in particular, to the reasoning of

132 d greater improvement in quality of life and psychopathology, and experienced greater involvement in

133 topiramate reduced binge eating and related psychopathology, and lisdexamfetamine and topiramate red

134 fathers as well as mothers, are affected by psychopathology, and may be amenable to treatment in way

135 nition, clinical phenomenology, comorbidity, psychopathology, and phenotypes in the first paper of th

136 r understanding of the mechanism of risk for psychopathology, and that tailored approaches to prevent

137 et the molecular mechanisms underlying these psychopathologies are not fully understood.

138 Coexistent psychopathologies are suggested to include depression an

139 Finally, we show that early life stress and psychopathology are each associated with these markers o

140 At a group level, differences related to psychopathology are seen for gray and white matter volum

141 The states called "psychopathology" are very diverse, but Lane et al.'s sin

142 iatric research may benefit from approaching psychopathology as a system rather than as a category, i

143 end to explain brain differences observed in psychopathology as an underlying (causal) neurobiologica

144 In recent years, the boundaries of psychopathology as defined by diagnostic categories have

145 firmatory bifactor model, describing overall psychopathology as well as four orthogonal dimensions of

146 the putative role of oxytocin and effects of psychopathology, as well as the most recent work on the

147 tential therapeutic use for the treatment of psychopathologies associated with anxiety, fear, and soc

148 We examined psychopathology at age 12 years in a cohort of Romanian

149 rm, suicide, health service use, and general psychopathology at posttest and follow-up.

150 are considered to be a product of choice, or psychopathology beyond volitional control, or perhaps bo

151 nce for the increased vulnerability for some psychopathologies, but perhaps increased resilience for

152 r time is a hallmark of depression and other psychopathologies, but the mechanisms supporting the abi

153 ore critical for understanding the origin of psychopathology, but the molecular mechanisms that trigg

154 ap that is important for understanding human psychopathology by combining molecular manipulations use

155 k for suicide attempt among individuals with psychopathology by reducing their ability to respond ada

156 at has suggested that biological accounts of psychopathology can exacerbate perceptions of patients a

157 Although PANSS Total and General Psychopathology changes were influenced by genotype, sig

158 choice behaviour and may offer insights into psychopathologies characterized by dysfunctional decisio

159 Yet, stress also precipitates psychopathologies characterized by social withdrawal suc

160 Stress is implicated in psychopathology characterized by cognitive dysfunction.

161 procedures relevant to schizophrenia-related psychopathology, combined with in vivo single-unit neuro

162 d greater improvement in quality of life and psychopathology compared with those with longer duration

163 ividual differences in neural phenotypes and psychopathology cosegregate as they fall through the fam

164 ii) higher prenatal parental risks (maternal psychopathology, criminal behaviors, substance use) asso

165 sity and the presence or absence of lifetime psychopathology (depressive, anxiety, and substance use

166 mportance of shared neural substrates across psychopathology, despite likely diverse etiologies, whic

167 stress-response system that is implicated in psychopathology, developmental differences in the respon

168 The effect of psychopathology dimensions on behavioral performance and

169 Moreover, some other crucial phenomena of psychopathology do not fit this theory: the role of nega

170 ital status, social deprivation, severity of psychopathology, duration of index CRT episode, first co

171 sease (HD) mutation carriers experience some psychopathology during their lifetime, varying from irri

172 n and grouped neuroticism with internalizing psychopathology (e.g., depression or anxiety).

173 ese hidden wounds may help prevent and treat psychopathology emerging after childhood trauma.

174 and externalizing dimensions), to a general psychopathology factor or to a combination of these expl

175 exerted almost exclusively through a general psychopathology factor representing the shared effect ac

176 and later negative life outcomes, including psychopathology, focus on the mediating negative impact

177 y phenotypic risk to develop anxiety-related psychopathology, for accelerating the development of imp

178 178 young adults (73 males) without current psychopathology from a community sample followed since b

179 edicated participants and those with current psychopathology from analyses.

180 Youths and parents were interviewed for psychopathology, functioning, treatment, and familial ps

181 e (g = 0.40; 95% CI, 0.22-0.58), and general psychopathology (g = 0.32; 95% CI, 0.09-0.55), with no d

182 Studies examining psychosocial stress and psychopathology had less consistent results, with 67% of

183 bes how research on genetic contributions to psychopathology has elucidated the nature of risk for tw

184 Research into the causes of psychopathology has largely focused on two broad etiolog

185 ; however, the impact of this locus on human psychopathology has not been fully explored.

186 w research on environmental contributions to psychopathology has targeted early temperament, its asso

187 people and broadening conceptualizations of psychopathology have triggered concerns about a dispropo

188 iritual healer and precise identification of psychopathology helped to disentangle the merely uncommo

189 ders (n=60) or no lifetime history of Axis I psychopathology (ie, healthy controls; n=26).

190 ma-exposed adults with severe trauma-related psychopathology (ie, posttraumatic stress disorder, majo

191 o monitor and reduce the long-term burden of psychopathology in 22q11.2 deletion syndrome.

192 lead to inappropriate circuit refinement and psychopathology in adverse situations.

193 typic and genetic structure of internalizing psychopathology in children and adolescents.

194 rly foster care slightly reduced the risk of psychopathology in children who had been living in insti

195 opment of maltreatment-related externalizing psychopathology in children.

196 care placements is an important predictor of psychopathology in early adolescence.

197 Literature on psychopathology in hearing-impaired children and adolesc

198 al material may underlie heightened risk for psychopathology in individuals that endure early-life tr

199 variation have been associated with risk of psychopathology in largely independent lines of research

200 Early-life adversity increases the risk for psychopathology in later life.

201 We did not identify any increased psychopathology in mutation carriers over non-carriers d

202 ciated with negative behavioral outcomes and psychopathology in offspring.

203 ) data for making accurate predictions about psychopathology in survivors of the 2008 Sichuan earthqu

204 dy-composition variables and eating disorder psychopathology in the AN group, and the only significan

205 While the increased risk of psychopathology in the biological offspring of depressed

206 ide novel evidence suggesting that affective psychopathology in TLE has a neurobiological correlate,

207 verity, implicating a role in trauma-related psychopathology in youth.

208 re present in association with dimensions of psychopathology in youth.

209 erarchical-dimensional conceptualizations of psychopathology, in which each form of psychopathology i

210 for understanding a range of reward-related psychopathologies including addiction.

211 -reward learning is thought to underlie many psychopathologies, including addiction, so understanding

212 nitive dysfunction is implicated in multiple psychopathologies, including attention deficit hyperacti

213 ve important implications for stress-related psychopathologies, including post-traumatic stress disor

214 dentifies a novel mechanism that can support psychopathology, including addiction.SIGNIFICANCE STATEM

215 be applied to the emergence (or decline) of psychopathology, including psychosis prediction, as well

216 a known vulnerability group for later severe psychopathology, including psychotic illness.

217 and characterized the associated spectrum of psychopathology, including the novel finding of anxiety

218 between groups survived adjustment for other psychopathology, indicating some specificity for psychot

219 f abnormal input to four selected domains of psychopathology (indiscriminate social behavior, posttra

220 The associations among psychopathology, intellect, and functioning were examine

221 through DISC-IV scores for three domains of psychopathology: internalising symptoms, externalising s

222 ar to confer resilience or susceptibility to psychopathologies involving prefrontal cortex (PFC) dysf

223 ar to confer resilience or susceptibility to psychopathologies involving prefrontal cortex (PFC) dysf

224 e associations between OT-pathway genes with psychopathologies involving social dysfunctions such as

225 nique effects of 2 major dimensions of child psychopathology, irritability and anxiety, on neural res

226 influencing the definition and treatment of psychopathology is also needed.

227 ns of psychopathology, in which each form of psychopathology is hypothesized to have both unique and

228 The role of emotional trauma in psychopathology is limited.

229 the heritability of neural systems linked to psychopathology is not sufficient to implicate them as i

230 Increased risk of psychopathology is observed in children exposed to mater

231 sk, and whether it is linked to pre-existing psychopathology, is not known.

232 ng presumed genetic risk for anxiety-related psychopathology, key neural activity involved in anxious

233 he risk of suicide attempt through a general psychopathology liability, this dimension should be cons

234 mans, such behaviors are also symptomatic of psychopathologies like obsessive-compulsive disorder (OC

235 innovative framework to understand and treat psychopathology linked to childhood trauma.

236 associated with an increased risk of severe psychopathology, mainly stress-related disorders and sui

237 e molecular mechanisms, variation in risk of psychopathology may emerge, particularly as a consequenc

238 al mechanisms through which genetic risk for psychopathology may emerge.

239 titative traits that may be components of BP psychopathology may enable genetic dissection of this co

240 eria (RDoC), a proposed dimensional model of psychopathology, may offer new insights into psychiatric

241 To define a more precise occurrence of psychopathology, more studies are needed.

242 ontrasting patterns of prefrontally governed psychopathology observed in males and females.

243 neurocognition, anxiety, depression, and the psychopathology of anorexia nervosa.

244 situations may contribute importantly to the psychopathology of GAD by proliferating anxiety cues in

245 ions that appear to duplicate aspects of the psychopathology of several neuropsychiatric disorders.

246 the possibility of the downstream effects of psychopathology on the brain.

247 Volumetric results were not influenced by psychopathology or maltreatment variables.

248 er, seem to influence either eating disorder psychopathology or psychological distress scores.

249 mily adversity (p<0.0001 for both), maternal psychopathology (p=0.013 and p=0.004), low intelligence

250 mal behavior, such as human impulsivity, and psychopathology, particularly behavioral addictions.

251 dictive disorders and comorbid externalizing psychopathology, particularly in adolescence.

252 enome included 50 traits from the domains of psychopathology, personality, cognitive abilities and ed

253 Individuals at risk for psychopathology presented an avoidant pattern of ocular

254 Externalizing psychopathology, prior depression, and specific "instrum

255 ples gleaned from the field of developmental psychopathology provide a framework for understanding mu

256 In novel network approaches to psychopathology, psychiatric disorders are conceptualize

257 e of Prevalent Forms of Child and Adolescent Psychopathology" published in the February 2011 issue of

258 neuronal computation can be used to explain psychopathology, ranging from impoverished theory of min

259 c and dimensional spectrum of trauma-related psychopathology, ranging from nontrauma-exposed psychiat

260 ting with a broad spectrum of trauma-related psychopathology, ranging from nontrauma-exposed, psychia

261 higher prevalence in those who had comorbid psychopathology, received benzodiazepines, and had early

262 A long-standing goal of psychopathology research is to develop objective markers

263 tem has been implicated in trauma and stress psychopathology, resulting in a growing interest in modu

264 which genetic variation and stress increase psychopathology risk.

265 ve identified a general liability factor for psychopathology-sometimes called the 'p factor'- that un

266 ratings, PANSS positive symptom and general psychopathology subscales, HAM-A, and HAM-D than for pla

267 =0.03) as well as PANSS Negative and General Psychopathology subscales.

268 g behavior may shed light on the etiology of psychopathologies such as addiction, for which high or l

269 Fear-related psychopathologies such as post-traumatic stress disorder

270 Fear-related psychopathologies such as post-traumatic stress disorder

271 rical predictions that might help explaining psychopathologies, such as addiction.

272 n individual, which is often associated with psychopathologies, such as addiction.

273 Chronic pain and stress-related psychopathologies, such as depression and anxiety-associ

274 ngth did not predict other common adolescent psychopathology, such as anxiety, attention deficit hype

275 ng (TD) comparison youth without significant psychopathology (TD group) (n = 220).

276 g comparison individuals without significant psychopathology (TD group).

277 ethylation mediate the molecular changes and psychopathologies that can occur following trauma.

278 the phenotypic expression of trauma-related psychopathology that comprises threat (ie, re-experienci

279 mental disorders, to specific dimensions of psychopathology (that is, internalizing and externalizin

280 ionally to the study of child and adolescent psychopathology, the nature of the relationship between

281 nt improvement in positive symptoms, general psychopathology, thought disturbance, and negative sympt

282 o predict, prevent, and treat stress-related psychopathology through the targeting of specific neural

283 imensions) provides an incomplete mapping of psychopathology to neurobiology.

284 erience stress without developing persistent psychopathology, varies from individual to individual.

285 Overall psychopathology was associated with both abnormal multiv

286 the same participants revealed that overall psychopathology was associated with decreased connectivi

287 Overall psychopathology was associated with elevated perfusion i

288 A dimensional measure of psychopathology was constructed using a bifactor model o

289 sociation of maltreatment with externalizing psychopathology was mediated by this perturbed pattern o

290 Psychopathology was not associated with communication or

291 Overall, the prevalence of psychopathology was not influenced by dexamethasone.

292 nsive involvement of neuroactive steroids in psychopathology, we hypothesized that the behavioral com

293 Factor scores of clinical psychopathology were calculated using an item-wise confi

294 Childhood adversity and lifetime psychopathology were each associated with shorter telome

295 and possible risk and protective factors on psychopathology were examined.

296 gh the article stated that the dimensions of psychopathology were measured using parent informants fo

297 ents in eating disorder features and general psychopathology were observed, but in general these chan

298 rly psychiatric patients had lower levels of psychopathology when assessed while wearing hearing aids

299 lopment of psychosis, the patient's specific psychopathology, with preeminently disturbed self-experi

300 th century, associations between smoking and psychopathology would increase.