ライフサイエンスコーパス: pteronyssinus

1 (HDM) extract derived from Dermatophagoides pteronyssinus.

2 of PBMC with beta-lactoglobulin and with D. pteronyssinus.

3 om the United Kingdom (n = 56) exposed to D. pteronyssinus.

4 sedust mite (odds ratio for Dermatophagoides pteronyssinus 0.20 [0.05-0.81], p=0.02; D farinae 0.20 [

5 f house-dust-mite allergen (Dermatophagoides pteronyssinus 1 [Der p1]) in the management of asthma is

6 5% in response to dust mite Dermatophagoides pteronyssinus, 40% in response to dust mite D. farinae,

7 and of IL-2 in response to Dermatophagoides pteronyssinus allergen 1 (Derp1) was lower in the salmon

8 Thus, we identified a new major D. pteronyssinus allergen as peritrophin-like protein.

9 are sensitized to the major Dermatophagoides pteronyssinus allergen, Der p 2.

10 Thus, Der p 23 represents a new major D. pteronyssinus allergen.

11 Parental hay fever and early exposure to D pteronyssinus allergens promote IgE polysensitization to

12 It reacted with IgE Abs from 74% of D. pteronyssinus allergic patients (n = 347) at levels comp

13 on of CD203c expression on basophils from D. pteronyssinus allergic patients.

14 ovocation tests (NAPT) with Dermatophagoides pteronyssinus, Alternaria alternata, Olea europaea and g

15 rgen provocation tests with Dermatophagoides pteronyssinus, Alternaria alternata, Olea europea, and a

16 pecific AIT should rely upon a mixture of D. pteronyssinus and D. farinae extracts, manufactured from

17 nce of mite allergens recorded by IUIS in D. pteronyssinus and D. farinae extracts, with groups 2, 8,

18 1 are major allergens from Dermatophagoides pteronyssinus and D. farinae, respectively.

19 Detection of Dermatophagoides pteronyssinus and Dermatophagoides farinae allergens Der

20 th a sublingual solution of Dermatophagoides pteronyssinus and Dermatophagoides farinae extracts or a

21 ophagoides farinae (Df) and Dermatophagoides pteronyssinus and from the mold Aspergillus fumigatus st

22 and group 2 allergens, respectively, from D. pteronyssinus and/or D. farinae species.

23 es cys-LT production by Df, Dermatophagoides pteronyssinus, and Aspergillus fumigatus.

24 erent allergens (cockroach, Dermatophagoides pteronyssinus, and D. farinae).

25 e peritrophic matrix lining the midgut of D. pteronyssinus as well as on the surface of the fecal pel

26 th species had a high ratio (> 10) of IgE D. pteronyssinus:B. tropicalis, whereas 68% of patients exp

27 n addition, specific IgE to Dermatophagoides pteronyssinus, Blomia tropicalis and their tropomyosins

28 library, showed 43% sequence homology to D. pteronyssinus Der p 5.

29 ls were pulsed with TSLP or Dermatophagoides pteronyssinus (Der p) allergen, before FACS phenotyping

30 ith a whole body extract of Dermatophagoides pteronyssinus (Der p), one of the causative agents of ho

31 early life and analyzed for Dermatophagoides pteronyssinus (Der p1) and Dermatophagoides farinae (Der

32 arinae (Der-f1, Der-f2) and Dermatophagoides pteronyssinus (Der-p1, Der-p2).

33 tly related to higher FeNO: Dermatophagoides pteronyssinus, Dermatophagoides farina, Blomia tropicali

34 en implemented for thirteen Dermatophagoides pteronyssinus enzymatic activities, associated with Der

35 We screened a D. pteronyssinus expression cDNA library with IgE Abs from

36 26.5%) of 722 participants ever had IgE to D pteronyssinus extract (>/=0.35 kUA/L).

37 rns of the IgE response to 12 molecules of D pteronyssinus from birth to adulthood and to investigate

38 , whereas 68% of patients exposed only to D. pteronyssinus had a ratio of > 10 (p < 0.001).

39 Survey 2, having information on cat/grass/D. pteronyssinus IgE levels and symptoms on exposure to ani

40 , and skin sensitisation to Dermatophagoides pteronyssinus in 205 cases and 399 controls aged over 16

41 .001) and on the bedroom floor (P=0.004), D. pteronyssinus in the bed (P=0.007), and cockroach allerg

42 In addition, D. pteronyssinus-induced CD4(+) CD25(+) FOXP3(+) T regulato

43 The house dust mite (HDM) Dermatophagoides pteronyssinus is one of most important allergen sources

44 erous allergen molecules of Dermatophagoides pteronyssinus is still unknown.

45 We show that Dermatophagoides pteronyssinus major allergen 1 (Der p 1), the major alle

46 s promote IgE polysensitization to several D pteronyssinus molecules, which in turn predicts current

47 llen (n = 108), followed by Dermatophagoides pteronyssinus (n = 105), Dermatophagoides farina (n = 96

48 12 purified allergens from Dermatophagoides pteronyssinus or D. farinae were assessed in sera from 1

49 lergens (NAPT-M), including Dermatophagoides pteronyssinus, pollens, alternaria, and dog epithelia, w

50 posures to aerosolized HDM (Dermatophagoides pteronyssinus) powder on 4 consecutive days in an allerg

51 cells (PBMC) to beta-lactoglobulin and to D. pteronyssinus; production of IFN-gamma on stimulation of

52 risons of IgE responses to B. tropicalis, D. pteronyssinus, rBlo t 5, and rDer p 5, showed that B. tr

53 ermatophagoides farinae and Dermatophagoides pteronyssinus, respectively.

54 .58-6.61], p for interaction=0.017), where D pteronyssinus sensitisation was common, but unrelated to

55 In the urban population, D pteronyssinus skin sensitisation was more strongly relat

56 ent who also had dust mite (Dermatophagoides pteronyssinus)-specific IgE antibodies from time points

57 ate basophil sensitization as measured by D. pteronyssinus-specific histamine release.

58 ints with various ratios of polyclonal to D. pteronyssinus-specific IgE (16:1 to 86:1), we demonstrat

59 ed that increased ratios of polyclonal to D. pteronyssinus-specific IgE did not attenuate basophil se

60 E antibody responses to B. tropicalis and D. pteronyssinus that were related to exposure: only 22% of

61 n from the house dust mite, Dermatophagoides pteronyssinus, that belongs to the papain-like cysteine

62 Sensitization to Ascaris and D. pteronyssinus was independently associated with asthma a

63 Dermatophagoides pteronyssinus was the main sensitizing aeroallergen in L

64 ities (51.1% and 18.8%, respectively), and D pteronyssinus was the most relevant aeroallergen (51.1%)

65 RNA-seq data from D. pteronyssinus were compared as estimates of allergen exp

66 IgE to the extract and 12 molecules of D pteronyssinus were tested by means of ImmunoCAP and micr

67 concurrently exposed to B. tropicalis and D. pteronyssinus, with patients from the United States and