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1 (IL-4), IL-5, and IL-13; and eosinophil-rich pulmonary granulomas.
2 .e., Th1-type) and fibrotic (i.e., Th2-type) pulmonary granulomas.
3 N-gamma or interleukin-4 and developed small pulmonary granulomas.
4 Mycobacterium tuberculosis residing within pulmonary granulomas and cavities represents an importan
5 sis-specific Abs, before infection developed pulmonary granulomas and dissemination patterns similar
6 th PPD in vitro for 36 hours had the largest pulmonary granulomas and the greatest collagen depositio
7 rized immune response generated two types of pulmonary granulomas around injected P4-coated beads.
11 surrounding necrotic and caseous regions of pulmonary granulomas by immunohistochemical staining.
12 se strongly suppressed the Th2-cell-mediated pulmonary granuloma development in naive or primed mice.
13 murine models of types 1 and 2 cell-mediated pulmonary granulomas elicited with Mycobacterium bovis o
14 nstrate that fibroblasts derived from murine pulmonary granulomas exhibit divergent expression of fun
15 hile infected Stat4-deficient mice developed pulmonary granulomas following schistosome egg injection
16 le bacterial loads in the lungs, less severe pulmonary granuloma formation and delayed dissemination
17 n IL-4 and IL-10 are completely defective in pulmonary granuloma formation and develop a highly polar
18 cell epitope (P4) of p38 was shown to elicit pulmonary granuloma formation and Th1-type cytokine prod
20 eported impaired adaptive, Th1 cell-mediated pulmonary granuloma formation in response to bead-immobi
22 dominant T cell epitope of p38 that elicited pulmonary granuloma formation was localized within pepti
23 tin regulates macrophage accumulation during pulmonary granuloma formation, and may explain the impai
29 mature, fibrotic M. tuberculosis-containing pulmonary granulomas in a mouse model of IL-10 deficienc
31 fibrotic response during the development of pulmonary granulomas in response to purified protein der
33 n protein, significantly reduced the size of pulmonary granulomas in unsensitized as well as egg-sens
37 ell involvement and eventual necrosis in the pulmonary granulomas of the infected mice lacking the NO
38 in primed mice with Th1 or Th2 cell-mediated pulmonary granulomas, respectively elicited by i.v. chal
39 els of Th type 1 (Th1) and Th2 cell-mediated pulmonary granulomas, respectively, elicited by i.v. cha
40 e present study examined the innate stage of pulmonary granuloma responses to bead-immobilized Th1- a
42 During active TB in humans a spectrum of pulmonary granulomas with central necrosis and hypoxia e
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