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1 In the cytoplasm, HDAC4 immunoreactivity is punctate.
2 side the nucleolus and diffuse nucleoplasmic punctates.
3 motes more robust and sensitive detection of punctates.
4 ing for phosphorylated EGFR colocalized with punctate accumulation of EGFR-GFP, indicating that a sub
5 hemicentin (HIM-4), found between BMs, forms punctate accumulations under the AC and controls BM link
6 the characteristic rod shape and developed a punctate acid-fast staining pattern with carbolfuchsin.
11 ils, PIP(3) is diffusely localized and forms punctate aggregates in activated p55(-/-) neutrophils, a
13 months of age, but at the time of symptoms, punctate aggregates were observed in cell bodies and pro
14 s and cytoplasm and showed a filamentous and punctate aggresome-like pattern compared with diffuse cy
16 ting high sensitivity and precision for both punctate and diffuse enrichment regions even in the abse
17 the absence of adenine, and cycling between punctate and diffuse phenotypes could be controlled by a
19 essing furrows in wild-type embryos, becomes punctate and loses its cortical association in the absen
20 The premature brain aging phenotype with punctate and multifocal WMHs was observed in ~70% of you
21 l as pronounced dilation in response to both punctate and prolonged stimulation of the contralateral
25 srupt PML nuclear bodies from their normally punctate appearance into heterogeneous filamentous struc
26 eflective spots in IR images corresponded to punctate areas of intense autofluorescence visible in fu
27 proteins redistributed to the membrane in a punctate arrangement when all of the accessory Sec compo
28 In contrast, wild-type HMGCLL1 exhibits a punctate as well as a perinuclear immunostaining pattern
29 ectopically coexpressing ppk transforms this punctate Balboa::GFP expression pattern to the uniform d
30 , CD36 or ICAM-1-binding parasites exhibited punctate binding to a subpopulation of HBMECs and bindin
32 D rats had more adult-generated neurons with punctate BrdU staining, an indicator of enhanced maturit
33 this study, we show that Tim-4 quickly forms punctate caps on contact with apoptotic cells, in contra
35 tion into Gb(3)-positive Vero cells rendered punctate cell surface VT1/VT2 binding uniform and subver
36 e chemotactic receptor K(D) displayed strong punctate centers of uropodial contractile force and stro
37 e with large variations in size and multiple punctate centromere loci exhibiting amplified copy numbe
38 ir C terminus in vivo and is co-localized in punctate clusters of CaV1.2 channels via that interactio
42 es in response to amino acid starvation to a punctate compartment partially colocalized with autophag
43 here the proteins are partially localized to punctate compartments, suggesting that Mtmr2-Mtmr13 may
44 ng from circular (Histoplasma capsulatum) to punctate (Cryptococcus neoformans) to labeling at the bu
53 et membrane-centric manner, progressing from punctate dimples, to the formation of a pinched liposoma
54 membranes of cancer cells, where it adopts a punctate distribution and induces membranolysis and rele
55 YK3 in M. truncatula and found that it has a punctate distribution at the cell periphery consistent w
60 e FLNa-binding domain of HCN1, abolishes the punctate distribution of HCN1 channels in neuronal cell
61 ophagic features such as cytosolic vacuoles, punctate distribution of LC3 and enhanced expression of
62 ture, two common organizational themes are a punctate distribution of myosin II and distinct patterns
63 a stimulated PKCiota activation and caused a punctate distribution of pPKCiota in the neurites and cy
64 ted protein 1 light chain 3 (LC3) levels and punctate distribution of the autophagic vesicle-associat
65 in both UL50-S216 and UL53-S19 resulted in a punctate distribution of the NEC in infected cells and a
66 HE also caused PKCbetaII translocation and a punctate distribution pattern in myocytes expressing thi
67 nce microscopy revealed both filamentous and punctate distribution patterns of vp13 in cells transfec
68 onal GFPPhiRz chimera was shown to exhibit a punctate distribution when coexpressed with Rz1, despite
70 e built a generative approach to modeling of punctate distributions that captures the essential chara
72 e LEs, PS-ASOs and LBPA were co-localized in punctate, dot-like structures, likely intraluminal vesic
73 hagosomes but not autolysosomes (assessed as punctate dual fluorescent mCherry-green fluorescent prot
74 compartment consists of regularly assembled punctate elements that cluster in progressively larger s
76 th corneal findings ranging from superficial punctate epitheliopathy to bilateral corneal melt with s
77 4p and their homologs Ysp1p and Sip3p target punctate ER-PM contact sites distinct from those occupie
84 rgo filled the cytoplasm with a diffuse, non-punctate fluorescence that was partially excluded from t
89 so defective, as characterized by irregular, punctate fluorochrome labeling and elevated proteoglycan
90 The sensitivity in detecting large focal, punctate focal and vessel segment leakage are 95%, 82% a
91 ents with large focal leak, 10 patients with punctate focal leak, and 5,846 vessel segments from 10 p
92 agnostic imaging allows for visualization of punctate focal mineralization in bone epiphyses during n
93 detect three types of leakage (large focal, punctate focal, and vessel segment leakage) and validate
94 plasm, yet all three proteins formed several punctate foci at the peripheries of pheromone-induced ce
96 d analysis revealed a portion of 2A-DsRed in punctate foci concentrated in the perinuclear region tha
99 tions, UgtP is sequestered away from FtsZ in punctate foci, and division proceeds unimpeded resulting
101 ft marker protein appeared to associate with punctate Gag fluorescence even in the absence of cell su
103 Cx43 in these connexin-deficient melanomas, punctate gap junction-like plaques were evident at sites
105 TBS, NMDA receptor activation, or levels of punctate glutamic acid decarboxylase-65/67 immunoreactiv
106 ith this antibody revealed high densities of punctate GlyRbeta immunoreactivity at inhibitory synapse
108 eyes with pinpoint leakage on FA (P < .001), punctate hypercyanescence on ICGA (P < .001), and pigmen
109 ous RD was associated with appearance of new punctate hypercyanescent spots on ICGA and leaking point
113 appeared to decrease, and was accompanied by punctate immunoreactivity within axon tracts suggestive
115 ally effective dopamine signals encoded by a punctate increase or decrease in dopamine levels provide
116 PBB levels increased in 90% of patients with punctate infarcts (<1.5 mL) and in all patients admitted
117 ndrome (aHR, 3.37; 95% CI, 1.52 to 7.46) and punctate inner choroiditis (aHR, 8.67; 95% CI, 2.83 to 2
118 To examine a large cohort of subjects with punctate inner choroidopathy (PIC) looking at risk facto
119 ocal choroiditis with panuveitis (MFCPU) and punctate inner choroidopathy (PIC)--for differences in c
121 ection of MtENOD8-SP-GFP from the vacuole to punctate intermediates and subsequently to symbiosomes,
123 ection of MtENOD8-SP-GFP from the vacuole to punctate intermediates preceding intracellular rhizobial
125 ht, Schirmer test I, presence of superficial punctate keratopathy (SPK), LG volume, and molecular ana
127 generalized peeling skin, leukonychia, acral punctate keratoses, cheilitis, and knuckle pads, which w
128 8F transgenic mice, which spontaneously form punctate keratotic lesions, scaly plaques, and large tum
132 he majority of bacteria and polar to diffuse punctate labeling with anti-Nsp3 for a minority of bacte
138 s of SD can occur, resulting in irreversible punctate lesions in the macula, the region of highest vi
140 and Bruch's membrane on SD-OCT, and 2) hard, punctate lesions that are smaller and undetectable on SD
142 I: 1.2, 61.4 [P = .03], respectively), while punctate lesions were exclusively observed in patients w
146 hagosome clearance, assessed as the ratio of punctate light chain-3 abundance in saline to chloroquin
149 izes to PtdIns(4,5)P2-enriched, tubular, and punctate lipid structures via N-terminal BAR and PH doma
155 orescence microscopy revealed an increase in punctate (lysosomal) LAMP-2A staining that co-localized
156 GEC1-A, and HA-GABARAP were distributed in a punctate manner and co-localized with KOPR-EGFP in the G
161 ange of temperatures and normal responses to punctate mechanical stimuli, both in the basal state and
162 ant (K483E) that associates exclusively with punctate membranes displayed decreased binding to phosph
163 ases with an unusual pattern of mislocalized punctate MHC II staining and intermediate levels of mRNA
164 sformation of the mitochondrial network into punctate mitochondria and resulted in a loss of mitochon
166 proteins, NHX5 and NHX6 are associated with punctate, motile cytosolic vesicles, sensitive to Brefel
169 KTF1 colocalizes with ARGONAUTE 4 (AGO4) in punctate nuclear foci and binds AGO4 and RNA transcripts
171 in S phase-enriched HeLa cells demonstrated punctate nuclear staining, and AAF co-localized with pro
173 the helicase-primase (H/P) complex exhibited punctate nuclear structures that resemble prereplicative
175 Histone modification profiles can be either punctate or diffuse which makes it difficult to distingu
176 genital skeletal dysplasia, characterized by punctate or dot-like calcium deposits in cartilage obser
178 The MCC portion was identified as stable punctate patches that correspond to furrows in the plasm
179 smembrane domain protein localized to stable punctate patches, similar to the plasma membrane subdoma
180 s were also clearly distinguishable from the punctate, "patchy" localization patterns of MreB-RFP(SW)
181 MTs localize to the tip of flagella and in a punctate pattern along the length, very similar, but not
182 sides of cardiomyocytes evolves into a clear punctate pattern as Cdh2-EGFP molecules outside the punc
183 )-tagged ICL (EGFP-ICL) was distributed in a punctate pattern at putative inhibitory synapses, identi
184 lized to the cell poles but formed a similar punctate pattern at the membrane when SecA2 was present.
185 was readily detectable and distributed in a punctate pattern characteristic for inclusion bodies.
186 Rpl1-GFP and Rps2-GFP was also observed in a punctate pattern in chloroplasts of tobacco and Arabidop
188 uble 208 TDP-43 CTF was present in a diffuse punctate pattern in neuronal cytoplasm and dendrites wit
189 stem cells, shows that Stwl is present in a punctate pattern in the nucleus that partially overlaps
190 Here we show that tagged HmLAR2-EGFP has a punctate pattern of expression in the growth cones of th
191 classical latency-associated transcripts, a punctate pattern of LANA expression, and episomal mainte
192 Initially, PrP(Sc) deposits had a small punctate pattern on the edge of muscle cells that coloca
193 ctopic expression displayed a characteristic punctate pattern on the endoplasmic reticulum (ER).
196 requires caspase 6, which is activated in a punctate pattern that parallels the pattern of axonal fr
198 s of new and old cell division as well as in punctate patterns along the long axis of rod-shaped baci
199 ny interpretations in the literature of such punctate patterns as helices should therefore be reconsi
200 on of CiaI-GFP in epithelial cells yielded a punctate phenotype not observed with the other C. jejuni
201 h mCherry-tagged FLOTILLIN4 (FLOT4), another punctate plasma membrane-associated protein required for
202 tation as a function of the frequency of the punctate pneumatic stimulus trains and stimulus site (gl
205 omotor nucleus, CR was specifically found in punctate profiles contacting superior rectus and inferio
206 a system that provides automated analysis of punctate protein patterns in microscope images, includin
208 vir or infection with a UL97 mutant led to a punctate rather than a continuous distribution of the NE
209 landscape of Drosophila may differ from the punctate recombination pattern observed in many mammals
210 t overexpressing reticulon protein induces a punctate redistribution of PDI intracellularly, both in
211 oper trafficking of STING to perinuclear and punctated region, known to be important for its activati
212 lysis of the retina and optic nerve revealed punctate regions of reduced cellularity in the ganglion
213 strated a symmetric leukoencephalopathy with punctate regions of restricted diffusion, typical of ALS
215 Furthermore, we observed cGAS localized in punctate regions on the cytosolic side of the chlamydial
216 features such as multifocal, coarse, raised, punctate, round to oval epithelial lesions in the cornea
218 atum, Ca(2+)-dependent reduction of the CYAM punctate signal was induced by depolarization or action
219 atients had the characteristic disseminated, punctate, slightly elevated, white epithelial lesions.
220 Annexin A2 colocalized with several LANA-1 punctate spots in KSHV+ body cavity B-cell lymphoma (BCB
221 During latency, LANA localizes to discrete punctate spots in the nucleus, where it tethers viral ep
222 y a shift in intracellular distribution from punctate spots to diffused cytoplasmic staining at a pep
228 t not in normal controls, LC3 and p62 showed punctate staining characteristic of autophagosome buildu
230 demonstrated a distinct increase in antibody punctate staining in the endothelium and Descemet membra
231 th in-situ hybridization also coincides with punctate staining observed in brain, SEG, thoracic, and
232 development proceeded, MAGI-1 occurred in a punctate staining pattern on stereocilia, which was main
235 ith the cationic polymer yielded perinuclear punctate staining reminiscent of endocytotic vesicles, t
237 ng in the endothelium and Descemet membrane; punctate staining was absent from both normal corneas an
238 he receptor's protein, we observed extensive punctate staining within the neuropil and on the membran
240 the brainstem of OA patients in response to punctate stimulation of their referred pain areas compar
243 significantly lower threshold perception to punctate stimuli and were hyperalgesic to the noxious pu
246 , TRIM12c is expressed in the cytoplasm as a punctate structure and induced upon IFN and pathogen sti
247 n regulatory light chain, localizes to small punctate structures and does not colocalize with large,
249 otein that colocalizes with Stt4 at cortical punctate structures and regulates the stability of this
251 sion levels recruits Dnm1 into mitochondrial punctate structures but fails to support normal fission.
254 hat ubiquilin 1 localizes TREX1 to cytosolic punctate structures dependent upon the TREX1 CTR and lys
256 saspora cells, CoSrc1 and CoSrc2 localize to punctate structures in filopodia that may represent prim
258 ypothesis that SV40 induces the formation of punctate structures in the ER membrane, called foci, tha
259 uria aurantia lectin (AAL) binds to numerous punctate structures in the nuclei of tachyzoites, bradyz
261 CDCP1 relocates from cell-cell junctions to punctate structures on filopodia after activation of EGF
262 1 family of tethering proteins, localizes to punctate structures on opposing surfaces of mitochondria
264 rapid and transient recruitment of NEMO into punctate structures that are anchored at the cell periph
265 oughout the entire cell membrane, aside from punctate structures that may correspond to regions of me
266 doplasmic reticulum (ER) and trafficked into punctate structures that were mutually exclusive with RV
269 iefly in the brain, where it associated with punctate structures within neurons and copurified in par
270 ly sea urchin embryo, Dsh is concentrated in punctate structures within the cytoplasm of vegetal blas
271 eceptor kinase-1 (GRK1) accumulated on large punctate structures within the inner segment in ARL3-Q71
273 characterized as being primarily located in punctate structures, but their images had all been annot
274 apical membrane, and redistributes to dense punctate structures, containing WNK1, within the cytopla
280 , but persistent events uniquely generated a punctate surface distribution over a 10 s interval.
281 esults indicate that diffuse cytoplasmic and punctate syntaxin-1-LIR are present in different subsets
283 hIP-seq data but also effective in analyzing punctate transcription factor ChIP datasets, making it w
284 oot apical meristem identified a novel gene, PUNCTATE VASCULAR EXPRESSION1 (PVE1), that is down-regul
285 moglobin (P = 0.0002) and the development of punctate vascular lesions on the colonic surface, which
287 a redistribution of LC3 from the cytosol to punctate vesicles indicative of authentic autophagosomes
288 gy as defined by an increase in LC3-positive punctate vesicles, double-membrane vacuoles, and decreas
290 itions (300 mOsm), human CLN3 was found in a punctate vesicular pattern surrounding the nucleus with
293 revealed a "supercomplex" structure within a punctate where elongation complexes aggregate through en
294 metabolism, are altered in association with punctate white matter lesions and "diffuse excessive hig
296 In a high proportion of infants, MRI detects punctate white matter lesions that are not seen on ultra
299 tamate excitotoxicity in the pathogenesis of punctate white matter lesions, but not necessarily in DE
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