ライフサイエンスコーパス: pup

1 of T cell-based immunity from dam to foster pup.

2 he external anatomy of the brain in a second pup.

3 with the entire procedure taking 15 min per pup.

4 remained elevated during slower decay at low Pup.

5 cleavage of the isopeptide bond formed with Pup.

6 l and the growth of m(+)/p(DeltaS-U) newborn pups.

7 as from Th1-biased dams to Th2-biased foster pups.

8 tal priority to nest viewing for pre-weaning pups.

9 increased in UPI/OIR compared to control/OIR pups.

10 onized "index" pups to uncolonized "contact" pups.

11 eductase, was decreased in hyperoxia-exposed pups.

12 nalysis and normal parturition and growth of pups.

13 sp29, causing the reduced body weight of the pups.

14 brainstem slices prepared from juvenile rat pups.

15 disease symptoms (e.g., deafness) in newborn pups.

16 irculation of lactationally-exposed neonatal pups.

17 fertility never resulted in birth of mutant pups.

18 sed milk energy output (MEO) and wean larger pups.

19 haviour and neuroanatomy of Ccdc88a knockout pups.

20 e with hyperthermia in either control or DNE pups.

21 in live-born, normal appearing affected male pups.

22 n control pups but remained depressed in DNE pups.

23 trol pups, although it did not change in DNE pups.

24 mber and sex ratios of subsequent litters of pups.

25 with heating in control pups but not in DNE pups.

26 positive control, but not in Cox7a1 knockout pups.

27 can efficiently support the generation of SC pups.

28 ltures, and in vivo in early postnatal mouse pups.

29 dings from calyceal terminals in newborn rat pups.

30 was similar between UPI/OIR and control/OIR pups.

31 tages of development in living, unrestrained pups.

32 n the P0 Mapt(-/-) , but not the Mapt(+/-) , pups.

33 ause any major effect on the survival of the pups.

34 nduced by sodium selenite in male Wistar rat pups.

35 cytic marker GFAP in the cortex of 7-day old pups.

36 n brain and/or lymph nodes of fetuses and/or pups.

37 GEs were comparable between preterm and term pups.

38 0, but not in D7 preterm relative to D4 term pups.

39 Salmonella Haifa was rare (1.1% pups; 2/175), but isolates were indistinguishable from t

40 This is shown for [ZrO](2+)[PUP](2-), [ZrO](2+)[MFP](2-), [ZrO](2+)[RRP](2-), and [Z

41 swabs of free-ranging and stranded grey seal pups (21.1%; 37/175) and compared with strains from the

42 average diastolic [Ca] nadir to 200 nM (at Pup = 24 mM/s).

43 rbificans was the most common isolate (18.3% pups; 32/175) and was indistinguishable from isolates fo

44 Salmonella Typhimurium was infrequent (2.3% pups; 4/175), mostly similar to isolates found in garden

45 Rat pups (a total of 72 controls and 72 DNE pups) were studi

46 Pup, a ubiquitin analog, is conjugated to proteins throu

47 results show that in calbindin-D9k knockout pups, a maternal vitamin D-deficient/low-calcium diet le

48 and become pregnant but did not suckle their pups after giving birth (NL), and 3) rats that were allo

49 nimal model to include heat exchange between pups allows the group to maintain one large huddle but e

50 ratio increased at 37.5 degrees C in control pups, although it did not change in DNE pups.

51 the separation between acoustically similar pup and adult vocalization categories among a physiologi

52 instem, thalamus, and cortex in one sea lion pup and the external anatomy of the brain in a second pu

53 e 021 (P021), rescued developmental delay in pups and AD-like hippocampus-dependent memory impairment

54 intestinal epithelial cells in both suckling pups and adults.

55 ficiently caused increased apnea in neonatal pups and airway hyper-reactivity in adult mice.

56 Tissues from E17.5 embryos, pups and dams were collected for choline/methyl metaboli

57 of reproductive and metabolic development in pups and has a persistent effect on their subsequent sen

58 evels were comparable in both preterm rabbit pups and human infants with and without IVH, but HA rece

59 nsgene in mice resulted in growth restricted pups and placentae with poor syncytialisation and dimini

60 activities of two enzymes, Dop (deamidase of Pup) and PafA (proteasome accessory factor A), the Pup l

61 ed levels being detectable early in enriched pups, and chromatin immunoprecipitation revealed an incr

62 sufficient to cause the apneas in Necdin-KO pups, and that fluoxetine may offer therapeutic benefits

63 The pups appear phenotypically normal until 13 days of age,

64 hoerus grypus) are typical capital breeders; pups are abandoned on the natal site after a brief suckl

65 Moreover, pups are born through natural mating and thrive through

66 According to mass balance calculations, the pups are exposed to considerable amounts (mug/d) of merc

67 However, V(I) was lower in DNE pups at both chamber temperatures, whereas the duration

68 re also more numerous in the LGEs of preterm pups at D3 compared with term rabbits at D0.

69 Across all three sites, packs which reared pups at high ambient temperatures produced fewer recruit

70 llowing outcomes between control and PNE rat pups at postnatal days 11-14: 1) the cardiorespiratory r

71 at the periphery continually displace warmer pups at the centre.

72 aintains a constant 'pup flow', where cooler pups at the periphery continually displace warmer pups a

73 Tissues were collected from pups at week 5 (W5), and their littermates at week 39 (W

74 ample, co-rearing with a male, which induced pup attraction to male odor, reduced activity in amygdal

75 d within 48 h of initiation of colonization; pups become progressively less susceptible to infection

76 We report that tight Pup binding and the limited degree of Dop interaction wi

77 Based on live pup births in the vaccinated and control groups (94.1% v

78 Moreover, pups born from mothers with a disruption of intestinal H

79 Consistent with these anatomical deficits, pups born to CB-treated dams exhibited compromised CCK-I

80 ammatory pathways in myometrium and neonatal pup brain.

81 FASD pup brains showed evidence of altered acetylcholine avai

82 V(I) increased with heating in control pups but not in DNE pups.

83 al infection occurred in 20/31 (65%) control pups but only 8/24 (33%) pups in the group vaccinated wi

84 rees C, V(I) returned to baseline in control pups but remained depressed in DNE pups.

85 ecays to resting Ca levels (<100 nM) at high Pup, but remained elevated during slower decay at low Pu

86 ostnatal day 0 (P0) heterozygous (Mapt(+/-)) pups, but not a complete loss of tau in the Mapt(-/-) li

87 Release propagation is facilitated at higher Pup by a larger LCR amplitude, whereas at low Pup by hig

88 up by a larger LCR amplitude, whereas at low Pup by higher background Ca.

89 and the demethylation capability develops in pups by the time of weaning.

90 maternal animals responded to the individual pup call exemplars having combinations of acoustic featu

91 n female mice by enhancing auditory cortical pup call responses.

92 Neural responses to pup calls were lateralized, with co-tuned and temporally

93 were quantitated in sera of individual PND 3 pups collected 1 hr postexposure utilizing ultra-high-pr

94 on extinction and plasticity in postweanling pups compared with adult rats.

95 rtality was 5-10 times greater in "silenced" pups compared with controls at P5 and P8 (p = 0.001) but

96 In all pups, core temperature was similar to chamber temperatur

97 and smaller litters (4.29 +/- l.02 vs. 8.50 pups/dam).

98 ight pupylated proteins results in preferred Pup deamidation over protein depupylation by this enzyme

99 defects and deliver only 2% of the number of pups delivered by control females.

100 cating that it is probably not controlled by pup demands.

101 dissipate body heat, and not indirectly via pup demands.

102 all immunogen-responding CD8(+) T cells were pup derived by 12 wk of age.

103 and allowing a distinction between dam- and pup-derived cells, we show that foster nursing by an imm

104 Pup-derived immunogen-responsive CD8(+) cells persisted

105 However, the pups develop overt ataxia by postnatal day 8-10 and die

106 Full-term pups developed in room air (RA) or an oxygen-induced ret

107 Consequently, neonatal pups died at birth due to respiratory insufficiency.

108 Groups of rodent pups display two such emergent properties.

109 Newborn CypA-deficient pups double stained with alcian blue and alizarin red ex

110 of stromal ESR1 caused mice to deliver fewer pups due in part due to inability of some embryos to imp

111 ales were unable to adequately nourish their pups, due to a disorganized epithelial compartment withi

112 NRF2 loss impaired survival of SCD pups during gestation and in the first 2 months of life.

113 ice present a dramatic phenotype with 60% of pups dying within 24 h of birth and the surviving animal

114 s was lower in uncoupling protein 1 knockout pups employed as a positive control, but not in Cox7a1 k

115 doses of peanut extract were administered to pups every day for 2 weeks before peanut sensitization a

116 mmunity than direct immunization in 5-wk-old pups (ex vivo assay of pup splenocytes).

117 body at postnatal day 1 (P1) and P3 in these pups exacerbated the remodeling defect and led to a reop

118 LCRs at higher Pup exhibit larger amplitudes and faster propagation wit

119 in dietary response, the cross-fostered SWR pups exhibited a significantly increased response in wei

120 Brpf1-deficient pups experienced early lethality due to acute bone marro

121 properties of this map are present when rat pups explore the world outside of their nest for the fir

122 aride (LPS)-induced dopaminergic deficits in pups exposed to LPS in utero.

123 higher prevalence of Salmonella was found in pups exposed to seawater, suggesting that this may repre

124 Finally, pups exposed to the odor in the presence of the conditio

125 Moreover, pups exposed to WIN in utero lacked constitutive CB1R-me

126 tocin signaling in the dam had been blocked, pups failed to learn.

127 glucose tolerance as early as 5 wk of age in pups fed a Western diet, ultimately causing diabetes.

128 Second, the huddle maintains a constant 'pup flow', where cooler pups at the periphery continuall

129 at which group sizes change, referred to as pup flow, is predicted at the critical temperature of th

130 ond observed emergent property--a continuous pup flow.

131 th abnormal cognitive behavior in CW-exposed pups following birth.

132 o mate and become pregnant and suckled their pups for 21 days before weaning (L).

133 cessed brain sections from seal and sea lion pups for Nissl substance, cytochrome oxidase, and vesicu

134 0%) diet lessens the phenotype, and knockout pups fostered to mothers fed a normal diet do not develo

135 A pup from each litter was euthanized weekly over a 7-week

136 e stress on gamma oscillations, we separated pups from dams once each day on PNDs 2-14 and recorded i

137 e with H10407, compared to 100% mortality in pups from dams vaccinated with sham vaccine or LTK63 onl

138 Rescue of pups from premature abortion with an SphK inhibitor occu

139 ress response results from separation of rat pups from the dam for three hours per day during a criti

140 Additionally, pups from the vaccinated group had reduced CMV transmiss

141 and dive data from recently-weaned grey seal pups from two regions of the United Kingdom (the North S

142 Here we show that pup gathering behaviour and associated auditory cortical

143 We propose that pup gathering learning triggers a transient epoch of inh

144 We found that calbindin-D9k null (knockout) pups generated from calbindin-D9k knockout females fed a

145 l-3-phosphate acyltransferase-4 (GPAT4) null pups grew poorly during the suckling period and, as adul

146 e produce less milk protein, leading to poor pup growth and postnatal death.

147 Furthermore, sodium selenite- injected rat pups had significantly higher levels of malondialdehyde,

148 y, an acute OT treatment of Magel2-deficient pups has a curative effect.

149 interactions between mouse mothers and their pups has recently been claimed to support coadaptation r

150 In lanugo pups, Hg concentrates in the hair, and molting serves as

151 ate the importance of early maternal care of pups in affecting offsprings' long-term behavioral chang

152 oduced fewer recruits than did those rearing pups in cooler weather; at the non-seasonal Kenya site s

153 20/31 (65%) control pups but only 8/24 (33%) pups in the group vaccinated with 10(6) PFU (P < 0.05).

154 Postnatal growth restriction occurred in pups in UPI/RA, but not in UPI/OIR.

155 l and hippocampal slices from neonatal mouse pups in vitro, but also reveals inhibitory GABA actions

156 uction of long-term potentiation (LTP) in PW pups, in contrast to its effects in adult animals.

157 Feeding high doses of peanut to pups induced tolerance to peanut protein.

158 he level of bacterial shedding is highest in pups infected intranasally at age 4 days and peaks over

159 imal set of assumptions about how individual pups interact, by simply turning towards heat sources, a

160 allows for active pup protection and mother-pup interactions crucial for pup threat learning.

161 the transient formation of a phosphorylated Pup-intermediate.

162 (DMT1) and ferroportin were not affected by pup iron status at 10 d of age but were strongly affecte

163 which the prokaryotic ubiquitin-like protein Pup is covalently attached to a lysine residue in target

164 s early as postnatal day 16 (P16) in the rat pup, just after eye opening and coinciding with the firs

165 nd molecular analyses indicate that hSRY(ON) pups lack innate suckling activities, and develop fatty

166 While at low Pup LCRs show smaller amplitudes, their larger durations

167 Reduced pup licking associated with suppressed LTP formation in

168 Furthermore, the Pup ligase PafA and the depupylase Dop share close struc

169 nd PafA (proteasome accessory factor A), the Pup ligase.

170 In rat pups, limb twitches exhibit a complex spatiotemporal str

171 However, the very low birth rate of SC pups limits practical use of this approach.

172 MTHFR protein levels were reduced in FASD pup livers, with lower concentrations of phosphocholine

173 A phosphorylation were demonstrated in a rat pup model of NEC.

174 AMA mice (38-41 weeks) at E17.5 had fewer pups, more late fetal deaths, reduced fetal weight, incr

175 loads, intrauterine growth restriction, and pup mortality comparable to that induced by pathogenic S

176 n the higher- and lower-dose vaccine groups, pup mortality was reduced to 1/24 (4%) and 4/29 (14%) pu

177 The immune response, maternal viral load, pup mortality, and congenital infection rates in the vac

178 n generates a negative environmental loop in pup-mother social communication.

179 Subsequently, pups (n = 4 . time(-1)) were killed at 13 different time

180 onses in the left cortex of maternal but not pup-naive adults.

181 Both biological and foster pups nursed by bitransgenic dams exhibited a dramatic de

182 in birth weights of UPI/OIR vs. control/OIR pups occurred.

183 shift of PVN frequency tuning should render pup odor-induced disinhibition more effective for high-f

184 Indeed, pup odors increased neuronal responses of PyrNs to pup u

185 The presence of pup odors significantly reduced the spontaneous and evok

186 erebellar external granule layer of P2 mouse pups of both sexes.

187 environment, we reciprocally cross-fostered pups of both species.

188 Pups of FASD mothers displayed short-term memory impairm

189 ice but recovers more slowly in the knockout pups on the vitamin D-deficient, low-calcium diet.

190 head direction cells--are present before rat pups open their eyes.

191 d of week 2 (postpartum day 14) when the rat pups opened their eyes.

192 may confer other, more cryptic, benefits to pups or allonurses, such as immunological or social bene

193 idence that allonursing provides benefits to pups or mothers.

194 tation in the thymus, the maternal or foster pup origin of immunogen-responding CD8(+) cells in foste

195 s it was 26/31 (81%) in unvaccinated control pups (P < 0.0001 for both groups versus the control grou

196 ation used congenic/syngeneic dam and foster pup pairs.

197 nificant delay to first litter and decreased pups per litter.

198 natal call sequence of its carriers and this pup phenotype in turn diminishes maternal care through a

199 [ZrO](2+)[RRP](2-), and [ZrO](2+)[DUT](2-) (PUP = phenylumbelliferon phosphate, MFP = methylfluoresc

200 of altered brain and behavior development in pups prenatally exposed to maternal immune activation (M

201 wever, 35% of the variability in NZ sea lion pup production is explained by latent by-catch, and the

202 s in the prokaryotic ubiquitin-like protein (Pup)-proteasome system (PPS), the bacterial equivalent o

203 t self-defense suppression allows for active pup protection and mother-pup interactions crucial for p

204 , especially during the energetically costly pup-rearing period.

205 Strikingly, pups receiving anti-BMP9/10 antibodies via lactation dis

206 Relative to wild-type pups receiving high perinatal n-6/n-3 ratios, subcutaneo

207 neous adipose tissue in 14-day-old wild-type pups receiving low n-6/n-3 ratios had more adipocytes th

208 Pups receiving the C57BL/6J or BALB/cJ mitochondrial gen

209 Transmission from nasally colonized pups required high levels of bacterial shedding in nasal

210 rog/ml CSC neonatally had increased rates of pup resorption.

211 lity was reduced to 1/24 (4%) and 4/29 (14%) pups, respectively, whereas it was 26/31 (81%) in unvacc

212 onal transfer to nonimmunized BALB/cJ foster pups resulted in much greater immunity than direct immun

213 Here we show how oxytocin enables pup retrieval behaviour in female mice by enhancing audi

214 nusual paternal care in rats, as measured by pup-retrieval tests.

215 dam immunogen are the product of the foster pup's thymus.

216 = 0.0022) and weight (p = 0.0024); gamma in pups separated for 180 minutes per day was not correlate

217 In control pups, separated for 15 minutes per day, gamma power had

218 ocytes derived from XLalphas knockout (XLKO) pups showed enhanced transferrin internalization.

219 Studies in suckling rat pups showed similar results with no capacity to regulate

220 All mothers abandoned their pups, showing that prolactin action on MPOA neurons is n

221 ge, 82% of immunogen-responding cells in the pup spleen were produced through maternal educational im

222 immunogen-responding CD8(+) cells in foster pup spleens was assessed.

223 Depletion of maternal Foxp3(+) cells from pup splenocytes illustrated a substantial role for lacta

224 unization in 5-wk-old pups (ex vivo assay of pup splenocytes).

225 ng undergoes a 'phase transition', such that pups start to aggregate rapidly as the temperature of th

226 developing alveolar macrophages in LPL(-/-) pups, suggesting that precursor cells were not correctly

227 odies conferred a dose-dependent increase in pup survival after challenge.

228 Crossover experiments showed that high pup survival rates after ETEC challenge were associated

229 re absolutely required for milk ejection and pup survival, an observation that redefines the signalin

230 the TNF inhibitor etanercept resulted in all pups surviving to adulthood, with normal body and spleen

231 organs of mice were evaluated using a novel pup-swapping approach.

232 rs consistently produce heavier (or lighter) pups than expected.

233 ion of spontaneous apnoeas was longer in DNE pups than in controls at 33 degrees C.

234 ent of CD8(+) T cells in nonimmunized foster pups that are specific for Ags against which the foster

235 and did not have a higher survival rate than pups that did not receive allonursing.

236 "Silenced" pups that eventually died took longer to initiate gaspin

237 nital heart disease can be modelled in mouse pups that harbour a mutation of the cardiac transcriptio

238 Pups that received allonursing were not heavier at emerg

239 of status epilepticus in postnatal day 7 rat pups that results in widespread neuronal injury, we foun

240 amined LCR regulation by SR Ca pumping rate (Pup) that provides a major contribution to fight-or-flig

241 In Necdin-KO pups, the genetic deletion of Slc6a4 or treatment with F

242 ssues from infection-resistant 9-day-old rat pups; the bacteria appeared to damage and penetrate the

243 l hippocampal development in rat fetuses and pups, there has been little research on the specific fun

244 tion and mother-pup interactions crucial for pup threat learning.

245 re CD4(+)MHC class II(+), accumulated in the pup thymus and spleen during the nursing period.

246 Further analysis of maternal cells in the pup thymus showed that a proportion was positive for mat

247 esent in milk, only T cells were detected in pup tissues.

248 chment of prokaryotic ubiquitin-like protein Pup to lysine side chains of the target protein via an i

249 We show that the early exposure of rat pups to enriching environmental conditions accelerates t

250 d in a more naturalistic context by exposing pups to interactions with the mother treating them rough

251 females direct help away from non-kin female pups to preserve future breeding opportunities for thems

252 t we gave mice at 30 degrees C either 6 or 9 pups to raise.

253 The pregnant animals carried the pups to term, and viral loads in target organs of pups w

254 there was a high ratio of colonized "index" pups to uncolonized "contact" pups.

255 ors increased neuronal responses of PyrNs to pup ultrasonic vocalizations.

256 At postnatal-day seven, rat pups underwent moderate or severe HI followed by 5 h at

257 other; and a more controlled paradigm, where pups underwent peppermint odor-shock conditioning that p

258 Wild-type pups used individually diverse sequences of simple and c

259 and complicated call types, but heterozygous pups used individually invariable call sequences with le

260 mula: see text]e was recorded in newborn rat pups using whole-body plethysmography under normoxic and

261 ut also inhibited delivery while maintaining pup viability in a noninflammatory model of preterm part

262 ons in the magnitude of maternal DNAemia and pup viral load were noted in the vaccine groups compared

263 f maternal viremia, congenital transmission, pup viral loads, intrauterine growth restriction, and pu

264 pansion to represent a behaviorally relevant pup vocalization category-contrary to expectations from

265 way produce highly specific effects in mouse pup vocalizations and establish the mouse as an attracti

266 Direct contact between pups was not required for transmission indicating the im

267 to weight, we included a genetic analysis of pup weight at birth and weaning.

268 ffected, and F2 litters showed no effects on pup weight or survival.

269 Pup weights and serum and mRNA of liver and kidney VEGF,

270 Milk yield and pup weights were recorded throughout lactation.

271 Alveolar morphology, milk yield, and pup weights were similar.

272 F1 pup weights were unaffected at birth but reduced at 2,00

273 ary structural deficits in hyperoxia-exposed pups were accompanied by a significant 28% decrease in D

274 to term, and viral loads in target organs of pups were analyzed.

275 Three-week-old male pups were evaluated for motor and cognitive function.

276 Neonatal mouse pups were exposed to >90% hyperoxia or room air during p

277 duced when she was exposed, and not when her pups were exposed, showing that the high temperature dir

278 Pups were injected with terbutaline on postnatal days 2-

279 t such capacity occurred at 20 d of age when pups were partially weaned.

280 an odor, froze when tested alone, whereas if pups were present, they remained in close contact with t

281 Forty male Wistar rat pups were randomly divided into a control group, an N-ac

282 ere used: a naturalistic paradigm, where rat pups were reared by an abusive mother; and a more contro

283 After breeding male turnover, fewer female pups were recruited in the new males' litters.

284 r during postnatal days 0 to 7, and then all pups were returned to room air from days 7 to 56.

285 Mutant pups were severely stunted during the suckling period, b

286 o simulate severe thermal stress, additional pups were studied at 33 degrees C and 43 degrees C.

287 h ketamine at a sedative dose for 2 hrs, and pups were studied at postnatal day 0 (P0) or P30.

288 Rat pups (a total of 72 controls and 72 DNE pups) were studied under thermoneutral conditions (chamb

289 ent regular reproductive cycles nor produced pups, whereas administration of exogenous gonadotropins

290 a, decreased growth, and truncal alopecia in pups which was restored following weaning.

291 ding by using odor-shock conditioning in rat pups, which engages the attachment system and produces a

292 experiments of wild-type pups with Nod2(-/-) pups, which then acquired altered cutaneous bacteria and

293 proportions of their body reserves to their pups, which they then abruptly wean.

294 ded activity from CA1 pyramidal cells in rat pups while they were trained on trace eyeblink condition

295 Newborn pups whose bodies primarily contained (56)Fe or (57)Fe w

296 Pups with hSRY activated (hSRY(ON)) are born of similar

297 IF), and the density of Iba1(+) microglia in pups with IVH.

298 in cross-fostering experiments of wild-type pups with Nod2(-/-) pups, which then acquired altered cu

299 nificant differences in the vocalizations of pups with the human Gnptab stuttering mutation compared

300 ZIKV was stochastic, in that not all fetuses/pups within the same dam had detectable virus and infect