ライフサイエンスコーパス: pupal

1 We found the pupal Abd-A expression pattern was conserved between spe

2 rphosis, failure to complete larval-pupal or pupal-adult ecdysis and abnormal wing development are am

3 TcADC mRNA was most abundant prior to the pupal-adult molt.

4 tinase, TcCHT5, was found to be required for pupal-adult molting only.

5 uently, the 'status quo' action of JH on the pupal-adult transformation is mediated by the JH-induced

6 TcE93 RNAi in Tribolium castaneum prevented pupal-adult transition and produced a supernumerary seco

7 Thus, Drosophila pupal/adult tissue progenitors can arise both by early a

8 n orchestrated transformation from larval to pupal/adult tissues.

9 ts are responsible for the generation of the pupal and adult abdominal airways.

10 mJHBP), which circulates in the hemolymph of pupal and adult Aedes aegypti males and females.

11 on of their synapses and cell bodies in late pupal and adult animals.

12 cells might be patterned and establishes the pupal and adult midgut as a novel genetic platform for i

13 s intact and that parkin is required only in pupal and adult muscle.

14 et-7-C locus is principally expressed in the pupal and adult neuromusculature.

15 ctions and 3D digital models for the larval, pupal and adult stage, allowed us to describe the morpho

16 rosophila, miR-125, is also expressed during pupal and adult stages of Drosophila development.

17 present only in males (third instar larval, pupal and adult stages) and in adult flies is restricted

18 ous system is sexually dimorphic during both pupal and adult stages.

19 Pupal and adult tissues form from imaginal cells, tissue

20 ted by alternative splicing catalyze larval, pupal, and adult cuticle tanning in Tribolium.

21 fascicles formed by lineages during larval, pupal, and adult stages using antibodies against membran

22 vous system were observed in pharate larval, pupal, and adult stages.

23 Within the ovary, stl is expressed in pupal basal stalks and in adult somatic cells of the pos

24 ds the pupa gradually recedes from the inner pupal case (an extracellular layer that encloses the pup

25 We propose that the inner pupal case induces elongating bristles to bend when they

26 of key processes such as emergence from the pupal case, locomotor activity, feeding, olfaction, and

27 Following eclosion from the pupal case, wings of the immature adult fly unfold and e

28 rinsic factors-the socket cell and the inner pupal case--and intrinsic factors--actin cytoskeleton as

29 yny, parthenogenesis, and oviposition in the pupal case.

30 hesized some 30 h prior to eclosion from the pupal case.

31 code proteins secreted in the saliva for the pupal case.

32 s a very different phenotype: short indented pupal cases and pupal death with head eversion defects.

33 The morphogenesis of these takes place in pupal cells and is mediated by the actin and microtubule

34 tively spliced RNAs appear in the larval and pupal CNS, but none shows sex specificity.

35 transcription factor that is correlated with pupal commitment (Zhou and Riddiford, 2001).

36 BR-C proteins shift with Z2 predominating at pupal commitment and Z4 dominant during early pupal cuti

37 Similar to pupal commitment in other tissues at later stages, activ

38 ation of broad expression is correlated with pupal commitment in the adult eye primordia.

39 one of the first molecular events underlying pupal commitment of both epidermis and wing discs.

40 pearance not only temporally correlates with pupal commitment of the epidermis on day 3 of the fifth

41 1.5 days after ecdysis, coincident with the pupal commitment of the wing.

42 al instar, MsE74B expression correlates with pupal commitment on day 3 and is induced to maximal leve

43 is study, we show that a molecular marker of pupal commitment, broad, is up-regulated in the wing dis

44 At the time of pupal commitment, in vitro experiments show that 20E up-

45 mordia initiate metamorphic changes, such as pupal commitment, patterning and cell proliferation.

46 reas E75D has roles both during the molt and pupal commitment.

47 nd pupal molts, with E75A also increasing at pupal commitment.

48 te the spatiotemporal expression of Delta in pupal cone cells.

49 ars to be an irreversible commitment to form pupal cuticle at the next molt.

50 l pupal phenotype, and the resulting grayish pupal cuticle exhibited many small patches of black pigm

51 d stage-specific cuticle genes and activated pupal cuticle genes, showing that br is a major specifie

52 re-expression and the formation of a second pupal cuticle in Manduca, but only in the abdomen of DRO

53 ut, unlike JH, it caused production of a new pupal cuticle on the head and thorax as well as on the a

54 upal commitment and Z4 dominant during early pupal cuticle synthesis.

55 nt phenotype: short indented pupal cases and pupal death with head eversion defects.

56 The pupal defensive secretion of the ladybird beetle Subcocc

57 xpression of the appropriate innexins during pupal development (but not later) rescues connection def

58 Photoreceptors form during Drosophila pupal development and acquire elaborate membrane structu

59 After pupal development and adult eclosion, unilateral (with o

60 ly expressed in R7 during the second half of pupal development and are necessary for R7 to terminate

61 vered that the critical period begins during pupal development and extends into adulthood, but temper

62 Our results show that amon is required for pupal development and identify a subset of neuronal cell

63 terminal differentiation is executed during pupal development and the photoreceptors adopt their fin

64 of normal thick filament length during late pupal development and thick filament stability in adult

65 Drosophila Runx protein Lozenge (Lz) during pupal development causes a decrease in cell death in the

66 transition proceeds normally, with extended pupal development compensating for reduced autophagy.

67 system and find that amon is required during pupal development for head eversion, leg and wing disc e

68 To examine the pupal development of the brain, we used Bodian staining

69 helial cells surrounding the sex comb during pupal development to promote sex comb rotation, a comple

70 eye disc glia through the earliest stages of pupal development to reveal the counterparts of these ce

71 affect the process of vein promotion during pupal development, and long-range from a single focus al

72 During pupal development, MN5 undergoes de novo dendritic growt

73 During the first half of pupal development, N-cadherin is required for R7 growth

74 larval atlas and proceeding forward through pupal development, one will be able to reconstruct adult

75 or of developmental timing during larval and pupal development, opposes EGF signaling in testes.

76 ain high levels of Cic throughout larval and pupal development, repressing the expression of vein-spe

77 (139) mutant animals die during mid and late pupal development, respectively, EcR(94) mutants arrest

78 During pupal development, the abdominal histoblast cells prolif

79 By 20% of pupal development, the divergence is more apparent, and

80 Early in pupal development, the neuropil organization of the two

81 r of immediate-early genes during Drosophila pupal development, yet is able to orchestrate distinct d

82 al with most mutant animals arresting during pupal development.

83 the normalized virus titer during larval and pupal development.

84 go marked changes in their morphology during pupal development.

85 scription factor broad (br), which specifies pupal development.

86 fferentiation program is attenuated prior to pupal development.

87 nd female first and second legs during early pupal development.

88 indirect flight muscles during mid stages of pupal development.

89 alled ommatidia during late larval and early pupal development.

90 ht muscles and central nervous system during pupal development.

91 ins stable throughout larval development and pupal development.

92 ession, is completed four days later, during pupal development.

93 ic interneurons of the flight circuit during pupal development.

94 mpairment of proliferation during larval and pupal development.

95 unidentified function that is essential for pupal development.

96 o generate three-cell secretory units during pupal development.

97 ed for joint development in the tarsi during pupal development.

98 it of Drosophila calcineurin, can suppress a pupal developmental arrest phenotype to adult viability.

99 r during adulthood along with the larval and pupal developmental stages, corrects the olfactory memor

100 In the tobacco hornworm, Manduca sexta, pupal diapause can be induced by exposure of fifth-insta

101 use archived expression data to compare the pupal diapause of S. crassipalpis with the adult reprodu

102 hat we describe also prevents the entry into pupal diapause when administered to larvae that are envi

103 and pathways differentially regulated during pupal diapause, dynamically regulated across diapause de

104 pendent on the duration of the overwintering pupal diapause.

105 tar larvae on the photoperiodic induction of pupal diapause.

106 s have an important role in the induction of pupal diapause.

107 arvae, and are then downregulated throughout pupal diapause.

108 ultural pests, DH prompts the termination of pupal diapause.

109 complex yield hybrid males that die prior to pupal differentiation.

110 programmed cell death (PCD) 24 to 48 h after pupal ecdysis (PE).

111 segment six [APR(6)s] die by 48 hours after pupal ecdysis (PE; entry into the pupal stage), whereas

112 uron network is remodeled immediately before pupal ecdysis by the emergence of 12 late CCAP neurons.

113 laces the cuticle between larval stages, and pupal ecdysis externalizes and expands the head and appe

114 ired for viability through its regulation of pupal ecdysis in a type II receptor Wishful thinking (Wi

115 anized layers of the network controlling the pupal ecdysis sequence: a modular input layer, an interm

116 ound to be entirely sufficient for wild-type pupal ecdysis, even after targeted ablation of all other

117 This sequence, which mediates pupal ecdysis, is governed by the serial release of seve

118 died at the pupal stage from the failure of pupal ecdysis, whereas larval ecdysis and adult eclosion

119 ysis progression and results in a failure of pupal ecdysis.

120 ion affects a locus previously implicated in pupal eclosion.

121 tle specifically during the late development pupal, emerging adult, and newly eclosed adult stages.

122 Pteromalus puparum, a pupal endoparasitoid of various butterflies, represents

123 e larval endoparasitoids but not to males or pupal endoparasitoids, showing that they maintain specif

124 of wound-induced syncytium formation in the pupal epidermis suggested direct membrane breakdown lead

125 erized actin structures in the ovary and the pupal epithelium.

126 nd Dac at this stage is not dependent on the pupal expression of Distalless (Dll), the main regulator

127 rd femur, but that they do not contribute to pupal expression of Ubx in the second femur.

128 ecycling endosomes in Drosophila postmitotic pupal eye epithelia.

129 In the Drosophila pupal eye epithelium, Rho1 GTPase regulates AJ remodelin

130 s in the postmitotic Drosophila melanogaster pupal eye epithelium, we demonstrate that Rho1 is requir

131 Patterning of the Drosophila pupal eye is characterized by precise cell movements.

132 f the fly chimaerin ortholog RhoGAP5a in the pupal eye led to an excess of interommatidial pigment ce

133 The Drosophila pupal eye provides a sensitive and accessible model for

134 Reducing Pyd function in the pupal eye resulted in mis-patterning of the interommatid

135 onal analysis in the Drosophila melanogaster pupal eye, we find that Cdc42 is critical for limiting a

136 ial precursor cells (IPCs) of the Drosophila pupal eye.

137 rates that MB neurons, which are born around pupal formation, acquire unique dendritic branching patt

138 do not undergo extensive morphogenesis until pupal formation.

139 In the pupal function described here, N signalling activates ta

140 This pupal function of dac is separate from its earlier role

141 peptide hormones that coordinate larval and pupal growth and development.

142 the TcCP30 gene had no effect on larval and pupal growth and development.

143 s have defects in larval tracheal growth and pupal head eversion, and Mmp2 mutants have defects in la

144 used global gene expression analysis in late pupal heads to better characterize the post-embryonic fu

145 sarcomeres, and thick and thin filaments in pupal IFM, are 25-30% longer than in wild type.

146 ion suppresses myofibril assembly defects in pupal indirect flight muscles and dramatically reduces m

147 Mutant pupal indirect flight muscles display normal myofibril a

148 ) rearrange to generate the highly organized pupal lattice, in which hexagonal ommatidial units pack

149 on of the Dll gene within bract cells of the pupal leg by EGF receptor signaling.

150 d sex-specific gene expression in Drosophila pupal legs.

151 Pupal lethal mutants were screened for specific defects

152 Lyra causes recessive pupal lethality and adult heterozygous Lyra mutants exhi

153 The high-protein diet also reduced the pupal lethality and the increased volume of acidic vesic

154 The pupal lethality of these dpp mutants was partially rescu

155 igned a drug screening strategy based on the pupal lethality phenotype induced by TDP-43 when express

156 s: a >or=50% loss correlated with larval and pupal lethality, disrupted nuclear structures, and in so

157 Strong knockdown of MCO1 resulted in pupal lethality, indicating that MCO1 is an essential ge

158 eride levels, small fat body cells and early pupal lethality.

159 % of NS1 transcripts also lead to larval and pupal lethality.

160 he appearance of melanotic tumors and larval/pupal lethality.

161 in the mesodermal derivatives, which led to pupal lethality; or in the central nervous system, which

162 tes that patterning events that occur during pupal life move the ommatidial units an additional 15 de

163 of Eyc during rhabdomere extension early in pupal life results in inappropriate retention of normall

164 ntified for extreme precipitation during the pupal life stage for univoltine species.

165 nd rhodopsin expression, is completed during pupal life.

166 ite puparium stage causes the formation of a pupal-like abdomen with few or no short bristles.

167 , we studied the molecular mechanisms of the pupal melanism in Spodoptera exigua.

168 xpressions of TH and DDC are involved in the pupal melanization of S. exigua.

169 e integument were compared during the larval-pupal metamorphosis process of the S. exigua wild type (

170 ull Nurf301 mutants do not undergo larval to pupal metamorphosis, and also enhance dominant-negative

171 zygotic null mutant, but rarely suffices for pupal metamorphosis, revealing later functions for slpr

172 terocytes and endocrine cells of a transient pupal midgut are selected from within the clusters of ad

173 ence of JH as there was no change during the pupal molt of allatectomized animals.

174 rgistic mortality occurred during the larval-pupal molt.

175 expressed transiently during the larval and pupal molts as the ecdysteroid titer begins to decline a

176 E74A is expressed late in the larval and the pupal molts when the ecdysteroid titer has declined to l

177 y 20-hydroxyecdysone (20E) during larval and pupal molts, with E75A also increasing at pupal commitme

178 r E75D mRNA expression during the larval and pupal molts.

179 of specific genes during development of the pupal nervous system and emphasizes the relevance of SOC

180 ression changes in the developing Drosophila pupal nervous system.

181 imaging of calcium transients from cultured pupal neurons, we confirmed that Ral does not participat

182 are the primary phagocytic cell type in the pupal neuropil.

183 Remarkably, however, mosaic pupal ommatidia with three or fewer Dip3(+) photorecepto

184 go metamorphosis, failure to complete larval-pupal or pupal-adult ecdysis and abnormal wing developme

185 a germline cyst with the basal stalk in the pupal ovary contributes to FSC niche formation.

186 This striking phenotype originates in the pupal ovary, where the developing germarium is shaped by

187 During the early pupal period (P6-P48) these primordia grow in size and d

188 ifferentiates during the first 2 days of the pupal period when terminal branches and synapses of seco

189 e autophagy and reduced viability during the pupal period--a phase when animals rely on autophagy for

190 omplex tracheal system that forms during the pupal period.

191 utant cells degenerate much later during the pupal phase of development.

192 ion of dsTcDDC into larvae produced a lethal pupal phenotype, and the resulting grayish pupal cuticle

193 In contrast, we show that in pupal photoreceptors Arr1-eGFP becomes internalized and

194 pical-basal polarity is compromised in early pupal photoreceptors, and no identifiable apical membran

195 or redirected cuticle production toward the pupal program when induced late.

196 zyme that is required for larval growth, pre-pupal/pupal viability and long-term adult lifespan.

197 vity is tightly regulated across time in the pupal retina and that epithelial cells in this tissue re

198 le pathway that affected caspase activity in pupal retina through hid and Inhibitor of Apoptosis Prot

199 omises normal developmental apoptosis in the pupal retina, while loss of ex has only mild effects.

200 his paper, we used the developing Drosophila pupal retina--looking specifically at the reorganization

201 adherens junction in cells of the developing pupal retina.

202 effects of Par-1 on Baz localization in the pupal retina.

203 elial patterning during morphogenesis of the pupal retina.

204 d abnormal E-cadherin localization in mutant pupal retinas, correlating with aberrant cellular arrang

205 As the larvae entered the pupal stage, pupal sizes reflected the overall larval weights.

206 Here, we analyzed the expression of the pupal specifier gene broad (br), and the effect on br of

207 g essential genes, lethality was high in the pupal stage and also found in the larval stages.

208 e (20E), whereas APR(4)s survive through the pupal stage and die at eclosion (adult emergence).

209 93 is expressed widely in adult cells at the pupal stage and is required for many patterning processe

210 ine this requirement temporally to the early pupal stage and use RNA-sequencing to identify SOCE medi

211 The majority of CCAP KO animals died at the pupal stage from the failure of pupal ecdysis, whereas l

212 ell fate determination, typically during the pupal stage of holometabolan species.

213 cap cells can develop into GSCs at the early pupal stage while the rest directly differentiate.

214 matic activity was detected at day 13 of the pupal stage with a peak at day 2 adult stage.

215 ours after pupal ecdysis (PE; entry into the pupal stage), whereas APR(4)s survive until adulthood.

216 peratures, which are likely to influence the pupal stage, are important for predicting the timing of

217 lth requires DPTP69D during the mid- to late-pupal stage, eclosion requires DPTP69D during the early

218 r of adjacent genes, animals die at an early pupal stage, indicating that fru's function is required

219 As the larvae entered the pupal stage, pupal sizes reflected the overall larval we

220 eloping (hemimetabolous) insect that lacks a pupal stage, we cloned br from the milkweed bug, Oncopel

221 arvae while another induced mortality at the pupal stage.

222 r cells contributing to the TDT at the early pupal stage.

223 ene Dchx1 and can be followed until the late pupal stage.

224 f pupariation and lethality during the early pupal stage.

225 showing that br is a major specifier of the pupal stage.

226 adult leg muscles develop during the ensuing pupal stage.

227 viorally simple larval stage and a quiescent pupal stage.

228 ture lethality and arrested development at a pupal stage.

229 expression of TcKr-h1 and TcBR-C during the pupal stage.

230 5' shortvein (shv) regulatory region at the pupal stage.

231 val muscle defects and semi-lethality at the pupal stage.

232 ocrine cell development takes place at a mid-pupal stage.

233 n of Elp3 results in larval lethality at the pupal stage.

234 tracts are found and such robo embryos reach pupal stages and die, while robo3 mutant embryos develop

235 lopmental delay, lethality during larval and pupal stages and hyperplasia of the hematopoietic organ,

236 expressed throughout embryonic, larval, and pupal stages as well as in adult males and females.

237 oreceptors lose neuronal markers during late pupal stages but do not re-enter a proliferative state o

238 Null animals survive to larval and pupal stages due to a large maternal contribution of CaM

239 atic activity ubiquitously during larval and pupal stages is lethal.

240 arvae, lethality occurs in the late larval - pupal stages of development.

241 reas Tlr is required later during larval and pupal stages of development.

242 The developmental times of the larval and pupal stages on I. batatas than on I. triloba were 37.01

243 We found that at mid-pupal stages the Drosophila melanogaster CNS neuropil wa

244 error-correction mechanism operating during pupal stages to reposition inappropriately orientated om

245 ction of the cDNA only during the larval and pupal stages was inconsequential to performance in olfac

246 l developmental delay (e.g. prolonged larval/pupal stages) often associated with decreased levels of

247 ecific isoform of troponin I during the late pupal stages, although the incompleteness of this transi

248 , with essential functions in embryogenesis, pupal stages, and adults.

249 yogenesis, low expression through larval and pupal stages, and greatly enriched expression in the adu

250 p in isolation from one another during early pupal stages, and that some patterning events are indepe

251 s promote terminal R8 differentiation during pupal stages, including the regulation of rhodopsin expr

252 ing 30% and 42% knockdown for early and late pupal stages, respectively.

253 erozygous dDP mutant animals develop to late pupal stages, the analysis of somatic mutant clones show

254 At pupal stages, the wing-hinge contraction contributes to

255 r visceral muscles is mainly required during pupal stages, when Hand participates in the proper hormo

256 esulting in female death at larvae and early pupal stages.

257 alters overall dimensions at the larval and pupal stages.

258 evelopment, including embryonic, larval, and pupal stages.

259 Homozygous mutant dronc animals die during pupal stages; however, at a low frequency we obtained ho

260 rence) from behavioural observations and for pupal survivorship (related to performance), showing tha

261 tissue fusion, embryonic dorsal closure and pupal thorax closure in Drosophila are useful experiment

262 criptional repressors in multiple larval and pupal tissues, including many DSF-expressing tissues.

263 the timing of the transition from larval to pupal to adult stages.

264 oth br-Z1 and br-Z4 caused the appearance of pupal traits in the adults, but disruption of br-Z5 had

265 morphogenetic processes during the prepupal-pupal transition in Drosophila.

266 During the larval-pupal transition, a switch from gene activation by EcR/U

267 most Acf1 null animals die during the larval-pupal transition, Acf1 is not absolutely required for vi

268 ch br expression is restricted to the larval-pupal transition, Of'br mRNA is expressed during embryon

269 During the larval-pupal transition, the levels of CDK8 protein positively

270 mutants proceeds normally until the prepupal-pupal transition, when final leg elongation is delayed b

271 ostmitotic neurons born during the larval-to-pupal transition, when transitions among three MB subtyp

272 ssure during the normal time of the prepupal-pupal transition.

273 and to shorten their bodies at the prepupal-pupal transition.

274 ing key developmental events at the prepupal-pupal transition.

275 ges correlate with the timing for the larval-pupal transition.

276 etabolism (SREBP activity) during the larval-pupal transition.

277 Pupal weight, adult emergence and lifetime fecundity of

278 urthermore, ectopic expression of Ubx on the pupal wing activated the eyespot-associated genes spalt

279 F-actin prehair to the distal vertex of the pupal wing cell has been shown to be dependent upon the

280 Prickle localizes to the proximal side of pupal wing cells and binds the Dishevelled DEP domain, i

281 We show that centrioles are polarized in pupal wing cells as a readout of PCP signalling, with bo

282 ited to a small region at the distal edge of pupal wing cells as in wild type, resulting in multiple

283 he PCP proteins accumulate asymmetrically in pupal wing cells where they are thought to form distinct

284 tial, symmetric subcellular distributions in pupal wing cells, Frizzled and Dishevelled become highly

285 and for suppression of endoreduplication in pupal wing cells.

286 Likewise, during pupal wing development, BMPs help to specify vein versus

287 rowing hairs, and we failed to detect Trc in pupal wing nuclei, implying that in this developmental c

288 ensitivity of the posterior crossvein in the pupal wing of Drosophila to reductions in the levels and

289 Pupal wing RNA was isolated from tissue prior to, during

290 the cytoplasm in differentiating larval and pupal wing vein cells, and we show that this cytoplasmic

291 and other tissues, and can diffuse into the pupal wing via the hemolymph.

292 of Ras to maintain vein cell identity in the pupal wing, our results indicate that Ras controls Shg l

293 it affects the range of BMP movement in the pupal wing, probably as part of a lipid-BMP-lipoprotein

294 hairs to distal cell edges in the Drosophila pupal wing.

295 s required for hexagonal cell packing in the pupal wing.

296 and inter-vein subregions of the Drosophila pupal wing.

297 ment of the posterior crossvein (PCV) in the pupal wing.

298 ormation along the proximodistal axis of the pupal wing.

299 ermis of both the embryonic germband and the pupal wing.

300 ecovery after photobleaching in prepupal and pupal wings, we have investigated the turnover of two ke