ライフサイエンスコーパス: pupillary

1 Pupillary abnormalities indicative of seizure activity a

2 sual acuity loss, visual field constriction, pupillary abnormalities, attenuated retinal arteries, lo

3 ors of the mammalian eye drive circadian and pupillary adjustments through direct projections to the

4 ing intensity were presented to one eye, and pupillary amplitude and constriction velocity were measu

5 changes in gain, we found that the measured pupillary and behavioral variables were strongly correla

6 measures that indexed motivation level using pupillary and saccadic response to monetary incentives,

7 The pupillary aperture was reduced significantly (42.11+/-20

8 l acuity (BCVA), intraocular pressure (IOP), pupillary aperture, glare, contrast sensitivity, endothe

9 lar lens (IOL) opacification confined to the pupillary area are reported from clinical practice in Lo

10 Pupillary areas of anesthetized C57BL/6 mice were measur

11 status was measured by retinoscopy along the pupillary axis and at 15 degrees intervals along the hor

12 rrors were measured by retinoscopy along the pupillary axis and at eccentricities of 15 degrees , 30

13 ed by streak retinoscopy performed along the pupillary axis and at eccentricities of 15 degrees, 30 d

14 assessed by retinoscopy performed along the pupillary axis and at eccentricities of 15 degrees, 30 d

15 and axial dimensions were measured along the pupillary axis by retinoscopy and A-scan ultrasonography

16 efractive development was assessed along the pupillary axis by retinoscopy, keratometry, and A-scan u

17 rior vitrectomy and the IOL may be used as a pupillary barrier to prevent loss of lens fragments.

18 In the presence of pupillary block (+PB), AOD500 decreased 25% and 36% for

19 (2) in the presence (+PB) versus absence of pupillary block (-PB) to quantify the effect of dynamic

20 positioning group, and IOP increase (n = 9), pupillary block (n = 1), choroidal effusion (n = 2), CME

21 s: crowded-angle (CR), lens subluxation (LS) pupillary block (PB), and plateau iris syndrome (PL).

22 One case developed postoperative pupillary block and 1 case required endothelial transpla

23 etter efficacy than C3F8 without the risk of pupillary block and thus should be preferred.

24 otruding Soemmering content causing absolute pupillary block became resolved after laser iridotomy an

25 on the first postoperative day to alleviate pupillary block caused by a nonpatent iridotomy.

26 laser peripheral iridotomy to eliminate any pupillary block due to primary angle-closure glaucoma.

27 Pupillary block glaucoma, steroid-induced intraocular pr

28 compensation, iritis, secondary glaucoma, or pupillary block occurred after surgery in any eye.

29 emmering-capsule-IOL complex caused relative pupillary block similar to a phakic eye and was successf

30 y dynamic pupillary block, but the effect of pupillary block was not as large as that of the dilator

31 Pupillary block was observed in the early postoperative

32 ocation of the dilator muscle and by dynamic pupillary block, but the effect of pupillary block was n

33 treal injection of silicone oil secondary to pupillary block, inflammation, synechial angle closure,

34 ndary angle-closure glaucoma with or without pupillary block.

35 omy at the time of surgery serves to prevent pupillary block.

36 atures most consistent with greater baseline pupillary block.

37 ny ocular tissues, most commonly seen on the pupillary border and anterior lens capsule.

38 perior, inferior, nasal, and temporal to the pupillary center, to create oblique angles of incidence

39 case (1.5 vs 1.05), incidence of post-laser pupillary constriction (9.5% vs 1.23%), and anterior cap

40 c and photopic electroretinograms as well as pupillary constriction analyses revealed that rod and co

41 iris sphincter and ciliary muscle to mediate pupillary constriction and lens accommodation, respectiv

42 ious physiological responses to light, e.g., pupillary constriction and neuroendocrine regulation.

43 in circuits mediating circadian entrainment, pupillary constriction and other non-image-forming visua

44 vestibular influences on lens accommodation, pupillary constriction and regulation of intraocular cir

45 In sighted individuals, pupillary constriction decreased monotonically for at le

46 at low irradiance levels, and for sustained pupillary constriction during exposure to light in the l

47 adjusted to the elevation of TPLR threshold, pupillary constriction kinetics in most patients were si

48 y significant difference was observed in the pupillary constriction of the treated eye (P<0.05) compa

49 The melanopsin-mediated, sustained pupillary constriction phase response following cessatio

50 was compared with the photoreceptor-mediated pupillary constriction phase response following cessatio

51 nuation of the melanopsin-mediated sustained pupillary constriction response was significantly associ

52 disruption of the outer segment and reduced pupillary constriction response when compared with those

53 rations in the melanopsin-mediated sustained pupillary constriction response.

54 hotoreceptors repeatedly, elicited sustained pupillary constriction responses that were more than twi

55 an enhanced pupillary light reflex (PLR)-the pupillary constriction that occurs in response to light

56 ocular motor disorders, such as paradoxical pupillary constriction to darkness, benign tonic upgaze

57 from the observed (or measured) speed of the pupillary constriction to light.

58 n4(-/-) mice, in contrast, could not sustain pupillary constriction under continuous bright illuminat

59 The amount of light required for pupillary constriction was recorded after bleaching and

60 Our data show a clear linear increase in pupillary constriction with increasing log light intensi

61 Cs (ipRGCs) drive circadian-clock resetting, pupillary constriction, and other non-image-forming phot

62 on-image-forming visual responses, including pupillary constriction, circadian photoentrainment and s

63 nses differed from that necessary to trigger pupillary constriction, suggesting that photopotentiatio

64 short isoform (OPN4S) mediates light-induced pupillary constriction, the long isoform (OPN4L) regulat

65 light to drive circadian clock resetting and pupillary constriction.

66 During pregnancy, pupillary dark adaptation was strongly associated with s

67 repair visual acuity, postoperative afferent pupillary defect (APD), old age, scleral laceration, and

68 sease severity can cause a relative afferent pupillary defect (RAPD).

69 retina or choroid, poorer visual acuity, and pupillary defect were associated with visual field defec

70 nsistent with NAION, (3) a relative afferent pupillary defect, (4) observed optic disc swelling, and

71 atients have ocular abnormalities, including pupillary defects, although they principally have constr

72 l acuity less than 20/200, relative afferent pupillary defects, optic nerve pallor, and visual field

73 acuity and contrast sensitivity suggest low pupillary dependence for light distribution.

74 so induced a significant decrease in maximum pupillary diameter (0.49+/-0.17 mm, P=.005).

75 he in vivo permeability assay, the change in pupillary diameter at 30 minutes after pilocarpine admin

76 e detected a significant decrease in maximum pupillary diameter by 0.50+/-0.19 mm (P=.011) and in the

77 Changes in pupillary diameter correlated with pilocarpine-induced A

78 We found that the pupillary diameter rapidly varied according to perceived

79 ated sustained pupillary response (mean [SD] pupillary diameter ratios at a point in time, 0.18 [0.1]

80 Hemodynamic responses, pupillary diameter, and serum cytokines were determined

81 The effects of topical ibopamine on pupillary diameter, aqueous humor flow measured by fluor

82 ataract severity, cataract extraction, small pupillary diameters (<5.5 mm), defocusing, and excessive

83 Baseline pupillary diameters in Rpe65(-/-) and control mice were

84 Patients with LCA had baseline pupillary diameters similar to normal, but the TPLR was

85 ast changes could not be responsible for the pupillary differences.

86 microl saline) significantly attenuated the pupillary dilatation response to VS, when VS was applied

87 rating characteristic curve before and after pupillary dilatation were not found.

88 athecally [i.t.] in 5 microl saline) induced pupillary dilatation when observed 1 min after the end o

89 neurons in the thoracic spinal cord produces pupillary dilatation, we propose that oxytocin is a cent

90 xytocin within the spinal cord and to induce pupillary dilatation.

91 ectly, and thus is a mediator of VS-produced pupillary dilatation.

92 corneal light reflex axis, is independent of pupillary dilation and phakic status of the eye.

93 Pupillary dilation during cognitive tasks provides a bio

94 ce of pseudoexfoliation was looked for after pupillary dilation in either or both eyes at 1 or more l

95 Pupillary dilation responses were recorded during a digi

96 Pupillary dilation to increasing levels of monetary rewa

97 tural pupils, and then retested after stable pupillary dilation with neutral density filters of 0.0,

98 an subjects with narrow angles was low after pupillary dilation with tropicamide and oral acetazolami

99 f intersession testing, cataract extraction, pupillary dilation, focal plane, and gain settings on th

100 hermore, death was accompanied by unilateral pupillary dilation, which is indicative of uncal herniat

101 upil-involving third nerve palsy, and benign pupillary dilation--are discussed.

102 arts in reversed-contrast polarity and after pupillary dilation.

103 he El Greco fallacy by reviewing some recent pupillary evidence supporting top-down modulation of per

104 A total of 430 patients (8.7%) had a pupillary expansion device used during their cataract su

105 intraoperative vitreous prolapse, and use of pupillary expansion devices.

106 Pupillary fatigue waves became more evident with test du

107 (8/12) showed gradual miosis and periods of pupillary fatigue waves during the recording session.

108 the pupil diameter and the amplitude of any pupillary fatigue waves.

109 tting, and standing, and eyelid function and pupillary function testing, was completed on 3 young pat

110 opathic effects of diabetes primarily affect pupillary function, and the immunosuppressive effects of

111 tent of rod-, cone-, and melanopsin-mediated pupillary light reflex (PLR) abnormalities in diabetic p

112 ns of rod, cone, and melanopsin to the human pupillary light reflex (PLR) and to determine the optima

113 binocular pupillography was used to measure pupillary light reflex (PLR) in 44 healthy children (23

114 The mammalian pupillary light reflex (PLR) involves a bilateral brain

115 cement of visual function in rd/rd mice: the pupillary light reflex (PLR) returned almost to normal;

116 and cone photoreceptors (rd/rd cl) retain a pupillary light reflex (PLR) that does not rely on local

117 erwent repeated measurements of quantitative pupillary light reflex (PLR) using the Neurolight-Algisc

118 ng to bright surfaces results in an enhanced pupillary light reflex (PLR)-the pupillary constriction

119 sically photosensitive iris and thus a local pupillary light reflex (PLR).

120 n photoentrainment and severely disrupts the pupillary light reflex (PLR).

121 which include circadian photoentrainment and pupillary light reflex (PLR).

122 including circadian photoentrainment and the pupillary light reflex (PLR).

123 n-image forming visual processes such as the pupillary light reflex and circadian entrainment but als

124 l centers that mediate behaviors such as the pupillary light reflex and circadian entrainment.

125 ation for accessory visual functions such as pupillary light reflex and circadian photo-entrainment.

126 primarily nonimage visual functions, such as pupillary light reflex and circadian photoentrainment, w

127 n-image-forming visual functions such as the pupillary light reflex and circadian photoentrainment.

128 n non-image-forming visual functions such as pupillary light reflex and circadian photoentrainment.

129 Intraocular injection of AAQ restores the pupillary light reflex and locomotory light avoidance be

130 The sensitivity of the pupillary light reflex and negative masking (activity su

131 They also contribute to the pupillary light reflex and other behavioral and physiolo

132 elanopsin and rod-cone photoreceptors to the pupillary light reflex in humans, we compared pupillary

133 This spectrum matches that for the pupillary light reflex in mice of the same genotype, and

134 ults provide an anatomical substrate for the pupillary light reflex in the cat.

135 These animals showed a pupillary light reflex indistinguishable from that of th

136 In mammals, the pupillary light reflex is mediated by intrinsically phot

137 ediated persistent constriction phase of the pupillary light reflex may represent a surrogate biomark

138 In contrast, sensitivity of the pupillary light reflex was more severely reduced in rd1

139 The pupillary light reflex was reduced in patients with POAG

140 The central pathways subserving the feline pupillary light reflex were examined by defining retinal

141 er with basic neurological examinations (eg, pupillary light reflex) contributed heavily to a linear

142 ritical for competent circadian entrainment, pupillary light reflex, and other non-imaging-forming ph

143 ponses to light, pineal melatonin synthesis, pupillary light reflex, and sleep latency.

144 brain to control circadian photoentrainment, pupillary light reflex, and sleep.

145 masking behavior, melatonin suppression, the pupillary light reflex, and sleep/wake cycles.

146 including circadian photoentrainment and the pupillary light reflex, are thought to be mediated by th

147 retinal ganglion cells (ipRGCs) mediate the pupillary light reflex, circadian entrainment, and may c

148 onimage-forming visual functions such as the pupillary light reflex, masking behavior, and light-indu

149 esponses to environmental light, such as the pupillary light reflex, seasonal adaptations in physiolo

150 kinetic visual field, nystagmus testing, and pupillary light reflex.

151 ympathetic input to the islet grafts via the pupillary light reflex.

152 caque frontal eye fields (FEF) modulates the pupillary light reflex.

153 eration for negative masking but not for the pupillary light reflex.

154 t are different for negative masking and the pupillary light reflex.

155 is sufficient for reaching threshold for the pupillary light reflex.

156 ite, red, and blue colors; visual field; and pupillary light reflex.

157 rocesses including circadian rhythms and the pupillary light reflex.

158 es including circadian photo-entrainment and pupillary light reflex.

159 onse to unilateral ESV, while preserving the pupillary light reflex.

160 rcuit that mediates a very basic reflex, the pupillary light reflex.

161 synchronization of circadian rhythms and the pupillary light reflex.

162 ity, suppression of pineal melatonin, or the pupillary light reflex.

163 the regulation of sleep-wake states, and the pupillary light reflex.

164 nvolved in circadian photoentrainment or the pupillary light reflex.

165 s such as circadian photoentrainment and the pupillary light reflex.

166 the rods, cones, and ipRGCs that mediate the pupillary light reflex.

167 n nucleus, indicating its involvement in the pupillary light reflex.

168 o non-image-forming nuclei and an attenuated pupillary light reflex.

169 ation, indicating that these cells serve the pupillary light reflex.

170 the affected dog was functionally blind, and pupillary light reflexes and ERG response amplitudes con

171 lete ophthalmic ocular examination including pupillary light reflexes and laboratory examinations; co

172 ncluding entrainment of the circadian clock, pupillary light reflexes and melatonin synthesis.

173 Mice lacking rods and cones retain pupillary light reflexes that are mediated by intrinsica

174 The earliest clinical signs (reduced pupillary light reflexes) were seen at 2 to 3 weeks of a

175 as photic entrainment of circadian rhythms, pupillary light reflexes, etc.

176 s supported by reduced direct and consensual pupillary light reflexes, phenotypic presence of retinal

177 circadian entrainment, sleep induction, the pupillary light response (PLR), and negative masking of

178 ight including circadian entrainment and the pupillary light response (PLR).

179 ted in some cases by objective tests such as pupillary light response and nystagmography.

180 under continuous bright illumination to the pupillary light response and suggest the presence of a p

181 generate mice reduces the sensitivity of the pupillary light response at all wavelengths but does not

182 cells [ipRGCs]) are sufficient to drive the pupillary light response in mice.

183 ment-state distinct from that triggering the pupillary light response itself.

184 ectroretinogram becomes undetectable and the pupillary light response weakens.

185 o subserve circadian photic entrainment, the pupillary light response, and a number of other aspects

186 ex (marked dry eyes and dry mouth), abnormal pupillary light response, upper gastrointestinal symptom

187 entrainment of circadian rhythms, and to the pupillary light response.

188 nner and outer retinal photoreception to the pupillary light response.

189 Absent pupillary light responses (FPR 1; 95% CI, 0-7) or absent

190 ecithin-retinol acyl transferase (Lrat) have pupillary light responses (PLR) that are less sensitive

191 However, photoentrainment and pupillary light responses are preserved.

192 upillary light reflex in humans, we compared pupillary light responses in normally sighted individual

193 a very limited contribution to circadian and pupillary light responses under these conditions.

194 tients had at least a 2 log unit increase in pupillary light responses, and an 8-year-old child had n

195 Nonvisual photoreception (pupillary light responses, circadian entrainment, and in

196 The absence of pupillary light responses, corneal reflexes, and an exte

197 nfidence intervals (CIs) were calculated for pupillary light responses, corneal reflexes, and motor s

198 hotoentrainment of the circadian oscillator, pupillary light responses, photic suppression of arylalk

199 psin mutant (opn4(-/-)) mice were tested for pupillary light responsiveness by video pupillometry bef

200 rate amplitude (0.5 log) circadian rhythm of pupillary light responsiveness was observed in rd/rd mic

201 of the circadian clock to light-dark cycles, pupillary light responsiveness, and light-regulated horm

202 -)/(-);rd/rd mice showed significantly lower pupillary light sensitivity than rd/rd mice alone.

203 g of pigmented translucent iris cysts at the pupillary margin of each eye, confirmed with ultrasound

204 In predilation pupillary measurements, we detected a significant decrea

205 ere included, 6 with a unilateral congenital pupillary membrane and 1 with classic persistent fetal v

206 nsient ocular microvessel network called the pupillary membrane as a unique in vivo model for studyin

207 the 6 patients with a unilateral congenital pupillary membrane had 1 or more recurrences after a mem

208 increased as the capillaries of the anterior pupillary membrane regressed.

209 In contrast, histopathology of a recurrent pupillary membrane revealed collagenized fibrovascular t

210 Congenital fibrovascular pupillary membranes in infants are likely a variant of P

211 Histopathologic examination of 2 primary pupillary membranes showed fibrovascular tissue that did

212 The 2 patients without recurrences of the pupillary membranes underwent multiple iris sphincteroto

213 e lens reproliferation into the visual axis, pupillary membranes, and corectopia.

214 The 4 eyes manifested with pupillary membranes, immature anterior chamber angles, l

215 tural pupils, and then retested after stable pupillary miosis (assessed with an infrared camera).

216 clude a triad of ipsilateral blepharoptosis, pupillary miosis, and facial anhidrosis.

217 In Parkinson's disease, reduced pupillary modulation by incentives was predictive of apa

218 ine the relationship between complex eye and pupillary movements, collectively referred to as eye met

219 ular smooth muscle, including blood vessels, pupillary muscle and the ciliary body in mammals.

220 ncreases in systemic vascular resistance and pupillary mydriasis and lethality in five of six vascula

221 ich exhibited severe microphthalmia, reduced pupillary openings, disrupted fiber cell morphology, eve

222 bsent somatosensory-evoked potential, absent pupillary or corneal reflexes, presence of myoclonus, an

223 d phakic IOLs revealed unacceptable rates of pupillary ovalization, IOL rotation, and endothelial cel

224 Thus, the pupillary physiological response reflects the subjective

225 mon neuro-ophthalmologic finding was minimal pupillary reaction to light (25%).

226 Pupils were fully dilated, and pupillary reaction to light was absent in 7 of the 9 res

227 Visual acuity (VA), pupillary reaction, and optic disc findings were assesse

228 er age (median 44 vs. 53 yrs), more abnormal pupillary reactions (52% vs. 32%), and more intracranial

229 Coma Scale score, the Injury Severity Score, pupillary reactivity, and presence of midline shift.

230 tomography characteristics, injury severity, pupillary reactivity, mitochondrial haplogroups, and APO

231 -image-forming visual behaviors, such as the pupillary reflex and circadian photoentrainment.

232 nvisual light-sensing functions, such as the pupillary reflex and entrainment of circadian rhythms.

233 For the pupillary reflex evaluation, patients were tested in the

234 s that regulate the biological clock and the pupillary reflex in mammals, is homologous to invertebra

235 The pupillary reflex was an important determinant, regardles

236 s also affected saccade velocity and reduced pupillary reflex.

237 w false-positive rates: bilateral absence of pupillary reflexes more than 24 hours after a return of

238 6 months and absent motor response or absent pupillary reflexes or bilateral absent cortical response

239 ing light adaptation, circadian entrainment, pupillary reflexes, and other aspects of non-image-formi

240 ons including circadian photoentrainment and pupillary reflexes.

241 , collapsed PAS-positive lens capsule in the pupillary region.

242 nuation of the melanopsin-mediated sustained pupillary response (mean [SD] pupillary diameter ratios

243 and its activity was associated with larger pupillary response and better performance in the task.

244 atients were OFF dopaminergic drugs, both in pupillary response and saccadic peak velocity response t

245 d ipRGC function caused by glaucoma affected pupillary response and sleep quality.

246 The crucial metric was the growth of the pupillary response and the reduction of this response fo

247 used to characterize the association between pupillary response characteristics and alterations in re

248 ental assessment of various stimulus-induced pupillary response characteristics and was conducted at

249 Association of pupillary response characteristics with alterations in r

250 ERG recordings and tests of the consensual pupillary response confirmed the effectiveness of each d

251 o corneal permeability was quantified as the pupillary response over a 30-minute period to a dose of

252 ix control subjects we studied the binocular pupillary response to a variety of sharply defined colou

253 pid eye movement latency and the peak of the pupillary response to the blue flash (P = 0.004).

254 atients, like the control subjects, showed a pupillary response to the structured coloured displays,

255 The dark-adapted pupillary response was tested in 298 pregnant women aged

256 the control subjects, the patients showed no pupillary response when the coloured displays lacked sha

257 Light intensity was a strong predictor of pupillary response, regardless of baseline pupil size.

258 concurrently measured cortical activity and pupillary response, using functional near infrared spect

259 tive processes can be obtained from the slow pupillary response.

260 the relationship between light intensity and pupillary response.

261 radiance light, indicating that steady-state pupillary responses are an order of magnitude slower tha

262 with schizophrenia was investigated by using pupillary responses as a biomarker of task effort.

263 pillometer is designed to record and analyze pupillary responses at multiple, controlled stimulus int

264 ing a pupillometer, we recorded and analyzed pupillary responses at varied stimulus patterns (full fi

265 Pupillary responses did not attenuate after saturating l

266 ta/cm(2)/s retinal irradiance) and recording pupillary responses for 50 seconds after light cessation

267 sistent with the choices, eye movements, and pupillary responses of subjects who commit to the optima

268 nses; stressed individuals showed attenuated pupillary responses to action, hinting at a noradrenergi

269 explanation for the present findings is that pupillary responses to ambient light reflect the perceiv

270 Pupillary responses to blue light and red light were com

271 isual photoreceptors are required for normal pupillary responses to continuous light exposure at low

272 e photoreceptors and melanopsin in mediating pupillary responses to continuous light.

273 h depression and examined how differences in pupillary responses to emotional stimuli correlate with

274 e infrared camera digitally records afferent pupillary responses to graded light stimuli (-2.9 to 0.1

275 Pupillary responses to high-irradiance blue light associ

276 In glaucomatous eyes, reduced pupillary responses to high-irradiance blue light were a

277 r lactate, lower maximum glucose, and normal pupillary responses were all associated with survival.

278 These pupillary responses were compared with those of 19 age-m

279 In patients with POAG, pupillary responses were evaluated relative to standard

280 Effort allocation (pupillary responses) to the task increased as the proces

281 itudes, goal-directed task effort indexed by pupillary responses, and negative symptoms in schizophre

282 s demonstrated improvement in visual acuity, pupillary responses, color vision, and visual field.

283 cit in action-learning was also reflected in pupillary responses; stressed individuals showed attenua

284 Scotopic vision and pupillary responsiveness have typically been measured us

285 Pupillary responsiveness was expressed as the percent ch

286 Moreover, pupillary reward sensitivity declined with age.

287 Beehler pupil dilator, nylon iris hooks, and pupillary rings, including the Perfect Pupil, the Graeth

288 Parameters evaluated include pupillary ruff absence and abnormality, pupil edge pigme

289 Pupillary ruff and associated gonioscopy findings were g

290 Asymmetric pupillary ruff changes were associated with asymmetry in

291 The eye with the most pupillary ruff loss was 25% more likely to have the grea

292 i were equiluminant so that constrictions in pupillary size could not be ascribed to changes in light

293 es identified severe cataracts and thickened pupillary sphincter muscle.

294 le miosis was present in only 1 patient, and pupillary supersensitivity to 2.5% phenylephrine was not

295 ffect of supplemental iron and riboflavin on pupillary threshold (PT) and plasma retinol in nightblin

296 adaptation was assessed weekly by using the pupillary threshold (PT) test; plasma retinol concentrat

297 up and tended to have a small improvement in pupillary threshold scores (by 0.21 log candela/m2; P =

298 went a clinic-based assessment that included pupillary threshold testing and phlebotomy before and af

299 central areas of IOL opacification over the pupillary zone, confined to the anterior surface of the

300 om its capsule, which was left behind in the pupillary zone.