ライフサイエンスコーパス: push

1 Whereas by pushing 1-MeA into the syn conformation and by forming H

2 Viral eradication rates are pushing 100% for many HCV-infected populations, includin

3 (13)C-TrEnDi also pushed 24 PE and 6 PC lipids over the limit of quantitat

4 riant to incidental features: whether a girl pushes a boy or a button and whether we see it in real-t

5 Pushing a protein-containing solution through a protease

6 mand for sustainable chemicals and fuels has pushed academia and industry to search for alternative f

7 n dense populations [1-4] where they need to push against their surroundings to accommodate space for

8 l outcome' is measured in the number of H(+) pushed against the chemical gradient.

9 NA creates a pressure of tens of atmospheres pushing against the interior capsid wall.

10 Here we show that rather than pushing against the surrounding fluid, efficient swimmin

11 Therefore, the N-tier ring is pushed ahead by the C-tier ring during CMG translocation

12 he authors show that silks cannot be spun by pushing alone, and that natural spinning is dominated by

13 s in such systems lowers the basicity of the pushing amino-group(s) and increases the basicity of the

14 Nitrogen bases containing one or more pushing amino-group(s) directly linked to a pulling cyan

15 Potential push and pull forces at the tips of the invading cords w

16 m of a de-linkage model and a combination of push and pull incentive mechanisms.

17 ntial agreement on the need for a mixture of push and pull incentives and particularly those that ser

18 esults in unequal translation lengths in the push and pull regions associated with a pulse wave.

19 It allowed the fine monitoring of pushing and pulling forces generated by T-cells in respo

20 etical modeling of this behavior reveals the pushing and pulling forces that result in up to a 30-fol

21 ntrosome is positioned at the cell center by pushing and pulling forces transmitted by microtubules (

22 identified different regimes, involving both pushing and pulling forces, characterized by robust cent

23 k asymmetric cues can induce a misbalance of pushing and pulling forces, resulting in an abrupt trans

24 These kinetochore-attached K-fibres generate pushing and pulling forces, which combine with polar eje

25 The n-pi conjugation between the pushing and pulling groups in such systems lowers the ba

26 hoimino group, as well as those in which the pushing and pulling moieties are separated by a conjugat

27 ctions from X-ray scattering to develop the "push-and-pull" hypothesis, which helps to explain the in

28 two functions are necessarily coupled (i.e., push-and-pull) or independently controlled.

29 sliding filament mechanism that "engages" to push apart the spindle poles when poleward flux is turne

30 lly tilted onto COPII coats but appear to be pushed apart as the carrier grows.

31 Pictorially obvious notions of strangling or pushing are difficult to render in mechanically precise

32 meter 71mum), through which the emulsion was pushed at different applied pressure (200-500kPa) and nu

33 ask; the bias modification training entailed pushing away 90% of alcohol cues and 10% of soft drink c

34 Our discovery pushes back evidence of reproductive biology in the clad

35 unequivocal" termitophile so far discovered, pushing back the known evolutionary history of termitoph

36 Euprox furcatus (13.8 Ma) to crown Cervidae, pushing back the origin of crown deer to (at least) 4 Ma

37 effects caused through enabling athletes to push beyond normal physiological limits with the potenti

38 d experiments, the system simply breaks when pushed beyond this mean stress.

39 to a new conservative treatment, the "Nitro-Push Blind Technique".

40 the potential exhibits low effectiveness in pushing bosons into it.

41 ion 980-2500nm in reflectance mode using the push-broom approach.

42 translocases, including RNA polymerase, can push budding yeast Mcm2-7 double hexamers along DNA.

43 force range, temperature control and simple push-button operation.

44 s have evolved quickly over the last decade; pushed by a growing body of scientific data that both te

45 aging, we show that TubRC complexes were not pushed by filament polymerization; instead, they process

46 he prior view that the endoderm is passively pushed by the mesoderm.

47 Thus, pushing by the beta3-subunit on Asp is sufficient for he

48 ns indicate that these events reflect active pushing by the translocase.

49 her show that premature telomere dysfunction pushes cardiomyocytes out of the cell cycle.

50 omosomal microtubules of the central spindle push chromosomes apart during meiotic anaphase in oocyte

51 The observed pull-push circuit at the lowest-level sensorimotor loop provi

52 Flow was controlled gravitationally to push culture media through the chamber.

53 Blocking repair and pushing damaged DNA through the cell cycle using therape

54 ometry (GC-TMS) instrumentation was shown to push detection limits for these pesticides down to the h

55 erefore, the actin filament network does not push directly toward the surface but rather accumulates,

56 Globally, this is pushing discovery research of antiparasitic drugs toward

57 ble to assume that detection limits could be pushed down even further.

58 acid makes the molecules of the protein coat push each other while they are still stuck to the virus,

59 Similar ATP-dependent pushing events, but in the opposite (3' to 5') direction

60 ction fluorescence microscopy to detect such pushing events.

61 n antiquity, and may have created a powerful push factor for human migration.

62 on the Roman Empire's periphery and created push factors for migrations.

63 e boundaries of this area have been possibly pushed far beyond what people could imagine in the begin

64 drift tube have been developed, Intermittent Push Flow for a large range of mobilities, and Nearly-St

65 rds for the training of ophthalmologists and pushed for the advancement of excellence within the prof

66 on, as they presumably limit the overall net pushing force.

67 While their capacity to generate pushing forces by ratcheting growth is well known, conve

68 ld equally result from the redistribution of pushing forces due to a reorientation of MTs.

69 We conclude that pushing forces generated by microtubule polymerization a

70 play between cell-autonomous actin-generated pushing forces in the emerging cell and mechanical prope

71 Dynamic microtubule ends exert pulling and pushing forces on intracellular membranes and organelles

72 l [13-16], it remains elusive how collective pushing forces result from the combination of single cel

73 figuration of the MTs on the distribution of pushing forces that position the centrosome.

74 e of forces where kinesin-5 produces outward pushing forces to antagonize the inward pulling forces f

75 d thereby direct the spatial distribution of pushing forces, whereas the number, dynamics, and stiffn

76 crotubules buckle as they exert compressive, pushing forces.

77 This work may push forward a significant step toward multienergy harve

78 lagellum periodically to swing to eventually push forward the robot in the glass tube filled with liq

79 However, while BACE1 inhibitors are being pushed forward as drug candidates, a remarkable gap in k

80 action on the one hand due to the technology push from better simulation tools and new manufacturing

81 The FtsN-FtsA interaction pushes FtsA into an 'on' conformation that activates the

82 This fast-growing field will push further development of more accurate and efficient

83 As x-ray and electron tomography is pushed further into the nanoscale, the limitations of ro

84 wed that upon changing conformation arginine pushes Helix V, through interactions with the highly con

85 al-time or in a single snapshot, it is still pushing Here, we investigated the brain systems that fac

86 bility of translocases to chemo-mechanically push heterologous SSB proteins along ssDNA provides a po

87 order and hydrogen bond symmetrization, and pushes ice VII to ice X transformation to higher and hig

88 rats sustain normotension despite a genetic push in altering BP.

89 integration, as evidenced by a biomechanical push-in test, was significantly improved by FGF23 neutra

90 ich (i) HP triggers Mrr activity by directly pushing inactive Mrr tetramers to dissociate into active

91 Thus, arousal exerts a feedback pull-push influence on excitatory neurons-an inversion of the

92 By contrast, we identify a pull-push inhibitory circuit in frontal cortex that originate

93 s the gap by generating strong stresses that push into the matrix.

94 and around diagnosis, enabling the field to push into unchartered territory at the earliest stages o

95 Microparticles are guided to and pushed into microwells by fluid flow through small open

96 ubstrate above the channel so that it can be pushed into the channel by a two-helix finger of the HSD

97 C-terminal domain up toward the membrane or push it down toward the periplasm, suggesting a possible

98 e column creates a thinner reactive zone and pushes it toward the oxygen boundary, resulting in a sho

99 e and atmosphere during the Proterozoic Eon, pushing it away from the more reducing conditions preval

100 poles, can stabilize improper attachments by pushing mal-oriented chromosome arms away from spindle p

101 cludes changes to disturbance regimes, which push many ecosystems towards early-successional states.

102 However, tool-assisted foraging has also pushed many of our prey species to extinction or endange

103 ese data suggest that strategies designed to push mature OLs to reinitiate myelination may be benefic

104 ion of a chemical effector compound from the pushing microchannel, while simultaneously aspirating it

105 Aberrant microtubule-driven kinetochore pushing movements and tripolar mitotic spindles occurred

106 e hypothesis that emotion states function to push neural activity toward rapid and efficient action.

107 Our results, when combined with the on-going push of high-repetition-rate lasers (sub- to few MHz's)

108 m translocase-induced directional (5' to 3') pushing of the SSB toward the 3' ssDNA end, followed by

109 d morphometric analyses, we show that humans push off with greater peak dorsiflexion angles at all MT

110 metatarsophalangeal joints (MTPJs) prior to push off, which tightens the plantar soft tissues to con

111 ing that this species used different bipedal push-off kinematics than modern humans, perhaps resultin

112 capacity of the ankle plantar flexors during push-off.

113 ergy generated by the plantar flexors during push-off.

114 The cumulative effect is to push old OMP islands towards the poles of growing cells,

115 that flattens the overall cell morphology by pushing on the cell cortex.

116 Advancing protrusions of gliding cells push, on average, in the direction of motion.

117 Here we present optical pushing (OP), a single-molecule technique that is used t

118 r conformation affects the force required to push or pull a single molecule has not been explored.

119 divide into opponent populations that prefer push or pull displacements.

120 the oft-debated question of whether silk is pushed or pulled from the animal, and provides impetus t

121 As a cell pushes or pulls its nucleus through a small constriction

122 ous force-transduction models, including the pushing or pulling of MTs at the cortex and the pulling

123 nt it will unavoidably have to interact and 'push' other particles in order to execute a pattern of m

124 me single cell and how such techniques might push our biological understanding of mammalian immunity

125 To push our understanding of functional brain organization

126 edge, where its polymerization-based forces push out non-adhesive and motile protrusions.

127 In more severe cases, the embryo can be pushed out from the micropylar end, resulting in the bur

128 s, acting locally, other optical forces can 'push' particles on a wide area of illumination but only

129 less-than-expected choice outcomes and thus pushes people to seek out alternative courses of action.

130 Using ultrafast electro-optical pump-push-photocurrent spectroscopy, we find the yield of fre

131 strate that the general concept of "polymers pushing polymers" is helpful in understanding and quanti

132 in one hemisphere is hardly perturbed by the push-pull acceptors in the other, which suggests that el

133 rmation of an unprecedented system featuring push-pull architecture.

134 cement of the pi-basic pyrene with polarized push-pull aromatics should afford more powerful CPP acti

135 ulation of RGC signalling involves a dynamic push-pull between direct TRPV1 activation and PKA-depend

136 A series of push-pull BODIPYs bearing multiple electron-donating and

137 atively low fluorescence quantum yields, the push-pull BODIPYS were effective for cell imaging, readi

138 This is a consequence of the push-pull character of the electron donor twisted violog

139 pectroscopic characterization of a series of push-pull chromophores based on a novel coumarin scaffol

140 rt an enhancement of the 1D-character by the push-pull concept in the doped state - an important view

141 The synthesis of a series of push-pull derivatives bearing triphenylamine electron-do

142 ns are preferred, despite repulsion from the push-pull dipole.

143 A new class of push-pull dyes is reported based on the structures of be

144 rove intramolecular interaction, enhance the push-pull effect between the donor unit indacenodithieno

145 n ring from o-quinone methide precursors and push-pull enaminoketones has been developed.

146 ls have center-surround receptive fields and push-pull excitation and inhibition, including neurons w

147 nsformed by voltage-dependent properties and push-pull excitatory-inhibitory interactions.

148 A new class of push-pull fluorophores featuring the pentafluorosulfanyl

149 ur results suggest that greater antagonistic push-pull interaction between synchronizing and desynchr

150 The effect of push-pull interactions in a series of variously substitu

151 Push-pull is a canonical computation of excitatory corti

152 ne LGN ( approximately 40%), indicating that push-pull is key in the form vision pathway across speci

153 enter cortical Y-like cells in an unbalanced push-pull manner to generate orientation-selective, cue-

154 UMO energy gaps upon the installation of the push-pull moieties.

155 different solvents upon introduction of the push-pull moieties.

156 In the gas phase, most of the so-called push-pull nitrogen bases exhibit a very high basicity.

157 re and conjugation of various subfamilies of push-pull nitrogen bases: nitriles, azoles, azines, amid

158 strong basicity of biomolecules containing a push-pull nitrogen substructure, such as bioamines, amin

159 tatory neurons-an inversion of the canonical push-pull of feedforward input.

160 Three uncharged push-pull oxazol-5(4H)-ones were synthesized and thoroug

161 oduction and wintering habitat, motivating a push-pull paradigm to explain irruptions of Pine Siskins

162 ique based on electroosmosis (EO), called EO push-pull perfusion (EOPPP), that is in principle suitab

163 A series of unsymmetrical and symmetrical push-pull phenothiazines (3-7) were designed and synthes

164 Interestingly, we find the 1D-approach in push-pull polarons in agreement to the model, pointing a

165 s in the ground and doped state in a complex push-pull polymer.

166 portant view in light of the main purpose of push-pull polymers for photovoltaic devices.

167 ent the implementation of an electrochemical push-pull probe, which combines a microfluidic system wi

168 n oscillator, together with its accompanying push-pull read-out circuit that responds primarily to th

169 Twisted push-pull scaffolds with large and bright dithienothioph

170 Using this versatile method, a near-IR push-pull sensor was prepared installing the electron-do

171 By uncovering this push-pull shift between lateral and basal nuclei, these

172 amines, amino acids, and peptides containing push-pull side chains, nucleobases, and their nucleoside

173 racter and plain electronic structure of the push-pull structure.

174 The influence of the push-pull substituents on the spectroscopic and electroc

175 he intrinsic nonlinear optical properties of push-pull substituted azobenzenes.

176 The push-pull substitution of BDI also leads to sensitive fl

177 doindolone core fitted out with a conjugated push-pull system and a carboxy linker for a conceivable

178 out the differences between single-unit and push-pull systems to obtain the desired structural- elec

179 Single-well push-pull tests were conducted to measure RDX degradatio

180 d nitrate-reducing conditions, using in situ push-pull tests.

181 capped polyynes as precursors to substituted push-pull thiophenes was next presented.

182 A variety of push-pull type organic dyes are facilely synthesized thr

183 i-tert-butyl terpyridine ligand generates a "push-pull" force on the electrons upon excitation, impar

184 el that pools such neurons in an imbalanced "push-pull" manner, to generate orientation-selective cue

185 The dynamic "push-pull" pattern of load effects on visual and auditor

186 ical center-surround receptive fields had a "push-pull" structure of excitation and inhibition within

187 hydrochloride gives a species containing two push-pull-stabilized parent monochlorosilylenes that are

188 t thalamus, however, is center-surround with push-pull.

189 has the smallest receptive fields but lacks push-pull.

190 that combine excitation and inhibition from push/pull JONs in different ratios.

191 These results push quantum superposition into a new macroscopic regime

192 steady-state and generates a rebound effect pushing quiescent cancer cells back into the cell cycle,

193 quilibrium, incorporating feedback loops and pushing replication chemistry away from equilibrium.

194 specifically the one-way revolution and the push-roll model.

195 Bioethics pushes scientists to acknowledge that they operate not w

196 for future point-of-care diagnostic assays, pushing sensitivity towards single-molecule detection li

197 reasing resource partitioning in the Modern, pushing species past their baseline ranges of resource u

198 of gymnosperms creates compressive force to push stems upward.

199 These results indicate that random noise can push subthreshold receptor potentials across the transfe

200 Originally driven by pushing technological limits, it has become a tool of bi

201 In this issue, Yang et al. push technology boundaries to measure both voltage and c

202 Experiments that push temperatures beyond historic variation are indispen

203 reased, the expansions transitioned to being pushed, that is, controlled by growth and dispersal in t

204 Research-minded oncologists may push the avenues of evidence-based research by taking ad

205 escribe major evolving strategies for how to push the borders of STED imaging even further in life sc

206 The present survey intends to push the boundaries and summarise the state-of-the-art o

207 asing pace of drug discovery and the need to push the boundaries of unexplored chemical space, medici

208 rease and clustering of mechanical forces to push the centrosome toward the cell apical pole.

209 ngle c-subunits in the c-ring of F0, and can push the common axle shared by the two motors clockwise

210 ntibiotic over many individual cells, we can push the detection time to the biological response time

211 limate change; global warming is expected to push the ecotone northwards, at the same time resulting

212 oducts of the catalytic reaction in order to push the equilibrium and enhance the assay fold amplific

213 steps needed to answer crucial questions and push the field forward to bring the mirage into a tangib

214 It is thus important to push the frontiers of operando techniques to monitor inc

215 These needs often push the infrastructural boundary in crisis regions and

216 ea that relatively less-penetrating polymers push the more easily penetrating ones into nanosize chan

217 h high average controllability, predicted to push the network into easily achievable states, affected

218 indle microtubule minus-end protrusions that push the properly segregated chromosomes to the site of

219 pharmacological and genetic manipulations to push the SCN clockwork toward its limits and, by doing s

220 n ssDNA translocase (ATP-dependent motor) to push the SSB along ssDNA.

221 nerals provides sufficient extra moisture to push the system into a sustained heat pipe, where simula

222 In doing so, we push the technical limits of this information storage sy

223 ixed polarity and minus-end-out microtubules push the tip of the axon, consistent with kinesin-1 driv

224 nts reveal that the hydrostatic pressure can push the Tmstr to a lower temperature at a rate of 7.7 K

225 The rural development in the Amazonia pushed the agricultural frontier swiftly, resulting in w

226 We review recent efforts that have pushed the boundary of the vibrational spectroscopic ima

227 cientific applications in space and thus has pushed the development of their components including the

228 quality of the absorber(|)buffer interface, pushed the device efficiency up to 6.3% which is at the

229 and, mutation of uvrD, if anything, slightly pushed the distribution of TS/NTS ratios to higher ratio

230 into the "water-in-salt" electrolyte further pushed the energy densities of aqueous Li-ion cells clos

231 development of new hypotheses and tools and pushed the field forward.

232 esents a doubled-edged sword for OCCC, as it pushed the intracellular H2O2 threshold to enable more r

233 of hardware-based adaptive optics (HAO) has pushed the limits of optical imaging, enabling high-reso

234 wind bursts (WWBs) in early 2014 apparently pushed the ocean-atmosphere system toward a moderate to

235 The dilated glandular ducts pushed the uterine horn lumen to closure or dilation and

236 Thereby, it pushes the boundaries of single-molecule kinetics beyond

237 This discovery pushes the boundaries of the original idea of Kekule and

238 eaks, indicating that binding the first dUMP pushes the enzyme ensemble to further conformational ext

239 he strongly donating equatorial tetracarbene pushes the Fe-dx(2)-y(2) orbital above dz(2), 1 features

240 f actin treadmilling (polymerization), which pushes the front of a cell forward, and myosin-induced s

241 ntroduce SIM to LSFM because the combination pushes the lateral resolution to the physical limit of l

242 ic moduli imply that cytosolic pressure both pushes the membrane forward and compresses the actin cor

243 rejection of these steranes as contaminants pushes the oldest reported steranes forward to around 1.

244 Graphene-edge dielectrophoresis pushes the physical limit of gradient-force-based trappi

245 The compressed magnetic field pushes the plasma via the Lorentz force on a diamagnetic

246 This intersubunit communication pushes the Rag GTPases into either of two stable configu

247 Elongation of the Arabidopsis hypocotyl pushes the shoot-producing meristem out of the soil by r

248 t a global and proportionate increase in E/I pushes the system to states of generalized hyper-activit

249 The experiment pushes the target of quantum teleportation to the bigges

250 Pushing the current limits of AM technologies in future

251 milar to orthologs found in vascular plants, pushing the date of the underlying gene duplication and

252 with the concept of time and cost saving are pushing the development of portable, miniaturized, compa

253 ical excitation, is a promising paradigm for pushing the efficiency of solar cells beyond the Shockle

254 nd polymer elongation, respectively, thereby pushing the elongated polymer into BcsA's transmembrane

255 Pushing the emission wavelength of efficient ultraviolet

256 Emerging nano-scale technologies are pushing the fabrication boundaries at their limits, for

257 TC may be achieved through electron doping, pushing the Fermi surface (FS) topology towards leaving

258 Pushing the frontier of fluorescence microscopy requires

259 Pushing the frontiers of condensed-matter magnetism requ

260 structures that resemble in vivo organs are pushing the frontiers of human disease modeling and drug

261 t-of-care (POC) diagnostics technologies are pushing the frontiers of POC devices toward low-cost, us

262 listic pact with our intestinal counterpart, pushing the gut microbiome toward a dysbiotic layout, wh

263 However, by pushing the limitations of the traditional medium into t

264 2O3 power electronics devices will be key to pushing the limits of device performance.

265 and environmental issues, the possibility of pushing the reduction beyond the CO and formate level an

266 onic liquid as compared to aqueous solution, pushing the solution thermal denaturation beyond the boi

267 tematically cleaning via a plasma or locally pushing the tip into the substrate by a few nanometres,

268 bance (especially fire) may in many cases be pushing the treeline downslope.

269 Grazing 'pushes' the community towards larger cell sizes, whereas

270 s into resonant escape routes that, in turn, pushed them onto planet-crossing orbits.

271 lony edge, whereas the other sits behind and pushes them both along.

272 e anterior bulb and acts as a repellent that pushes them towards the CZ.

273 t the VECs to open a junctional gap and then push themselves across the gap by generating strong stre

274 urse microscopy, that these loops migrate by pushing themselves away from the colony.

275 ies abundances and that seasonal forcing may push these nonequilibrium dynamics to the edge of chaos.

276 ults suggest that future climate change will push this ecosystem away from conditions that maximize N

277 Here, we pushed this idea forward and examined, across all sleep

278 e resistance encountered by a seedling as it pushes through the soil causes inhibition of stem elonga

279 , and as each layer becomes wet, the analyte pushes through to the next membrane layers.

280 e solar cells and will prove critical in the push to commercialize this exciting new photovoltaic tec

281 g topic, which is partially explained by the push to conduct experiments on model systems under relev

282 In recent years, the push to foster increased technological innovation and ba

283 In contrast, the domain wall can be pushed to move in a direction with reduced anisotropy, w

284 izosaccharomyces pombe, the mitochondria are pushed to the cell poles by the spindle.

285 h established techniques, but they were both pushed to their limits by the challenge posed by the hig

286 tection strategies in recent years, a bigger push toward detecting TB in the shortest and easiest way

287 technology while leveraging the progressive push toward efficiency and value but also requires the b

288 rding opioid use and abuse, there has been a push toward greater regulation over prescriptions of opi

289 ience is likely to benefit from simultaneous pushes toward both greater integration across theories (

290 These findings are expected to provide a big push towards graphene-protected Cu plasmonics.

291 n contrast, the nonsulphated IdoA residue is pushed towards the (1)C4-chair conformer when the neighb

292 creasing temperatures, these cities could be pushed towards very different partitioning between runof

293 OH)2, naturally depleting the semiconductor, pushing towards intrinsic doping limit and enhancing ove

294 g, stereo-specific complex, the myosin heads push Tpm strand to the open, or O, state allowing myosin

295 As rapid climate change and other factors push tree populations into new areas, the successful est

296 es that can guide, accelerate, slow down and push up neurites in un-modified collagen scaffolds.

297 e lower crust beneath the LMS was folded and pushed upwards and the upper crust was removed by exhuma

298 We also study how the spatial spread of the pushed wave can be stopped by making gene drives uniquel

299 In this "pushed wave" regime, the spatial spreading of gene drive

300 tional magnetic resonance imaging (fMRI), we pushed young and old subjects to their working memory (W