ライフサイエンスコーパス: pyknotic

1 d contain multiple nuclei, some of which are pyknotic.

2 rphology, 97% of Cc scrape-loaded cells were pyknotic.

3 lei in untreated RCS rat retinas were highly pyknotic.

4 t, the cells progressively shrank and became pyknotic.

5 s, we investigated neuron density along with pyknotic and apoptotic (TdT-mediated deoxyuridine tripho

6 Similar patterns were obtained from both pyknotic and apoptotic cell quantification.

7 Their nuclei appeared pyknotic and fragmentary.

8 oss-sections are calculated and observed for pyknotic and mitotic nuclei.

9 ere was a striking increase in the number of pyknotic and T+ cells in both the GCL and in the INL of

10 such as internucleosomal DNA fragmentation, pyknotic and uniformly condensed nuclei, and loss of int

11 n is based primarily on correlations between pyknotic cell counts in development and counts of mature

12 pared to nonADX rats; estradiol also reduced pyknotic cell number compared to vehicle administration.

13 However, examination of the numbers of pyknotic cells and the numbers of BrdU-labeled cells at

14 However, beginning at E15.5 large numbers of pyknotic cells are evident in the trigeminal motor nucle

15 cell death, characterized by the presence of pyknotic cells containing double-strand DNA breaks, was

16 In the inner nuclear layer (INL), T+ and pyknotic cells first appeared on ED 8, reached maximum f

17 ndrogens significantly reduced the number of pyknotic cells in corticosterone-depleted rats.

18 to identify Cc-loaded cells) and by counting pyknotic cells in cryosections.

19 les and females, ADX increased the number of pyknotic cells in the dentate gyrus compared to nonADX r

20 uced by serum deprivation, and the number of pyknotic cells was counted.

21 were observed at all the stages, when T+ and pyknotic cells were abundant, but not on ED 4, when only

22 Pyknotic cells were seldom seen in either sex by day 15.

23 with intracellular Abeta immunoreactivity in pyknotic cells.

24 Pyknotic clusters at sites of major morphogenetic change

25 ed increase in the number and the density of pyknotic dentate and hilar neurons, in particular in ani

26 cits in both Purkinje and granule cells; (3) pyknotic figures are present in the juvenile DCN and in

27 In vivo, LKB1 is highly upregulated in pyknotic intestinal epithelial cells.

28 mmunolabel for endogenous BDNF was sparse in pyknotic ION neurons, suggesting that ION neurons with l

29 The density of pyknotic late OL progenitors was significantly increased

30 yte-derived macrophages, but membrane-intact pyknotic/necrotic cells are not.

31 ient mouse brains indicated large numbers of pyknotic neurons and neurons with marked cytoplasmic swe

32 Pyknotic neurons in adult PS/APP mice exhibited apoptoti

33 After hypoxic-ischemia, there were very few pyknotic neurons in the early phase, many pyknotic neuro

34 ew pyknotic neurons in the early phase, many pyknotic neurons in the intermediate phase, and extensiv

35 ongestion, hemorrhages, multiorgan infarcts, pyknotic neurons, and progressive siderosis.

36 neuropathology, including the persistence of pyknotic neurons, elevated cortical TUNEL reactivity, ly

37 by the loss of APC labeling and the gain of pyknotic nuclear morphology and propidium iodide labelin

38 ll BPs induce caspase-dependent formation of pyknotic nuclei and cleavage of Mammalian Sterile 20-lik

39 eria: (a) morphological indicators including pyknotic nuclei and cytoplasmic condensation; (b) DNA fr

40 opathologic findings of thermal coagulation (pyknotic nuclei and streaming cytoplasm).

41 d NMDA injection, including the formation of pyknotic nuclei and TUNEL staining.

42 s of detached retinas showed the presence of pyknotic nuclei in the outer nuclear layer and disruptio

43 was a substantial increase in the number of pyknotic nuclei in the trigeminal ganglia of trkB-/- at

44 significant difference between the number of pyknotic nuclei in trkA-/- and wild-type embryos at E11

45 In wild-type embryos, the number of pyknotic nuclei increased from E11 to peak between E13 a

46 d either with propidium iodide, which stains pyknotic nuclei intensely, or with terminal transferase-

47 Numbers of pyknotic nuclei peaked at E6 and at E9, revealing an add

48 t of these osteoclasts were giant cells with pyknotic nuclei that were adjacent to superficial resorp

49 agic infiltrate on a bed of hepatocytes with pyknotic nuclei throughout the treatment zone.

50 of cell death containing shrunken cells with pyknotic nuclei were also evident.

51 TUNEL-positive (T+) cells and pyknotic nuclei were first detectable in the ganglion ce

52 foci of glial cells, lymphocytes, and a few pyknotic nuclei were observed in the brain.

53 Although pyknotic nuclei were sometimes encountered, most of the

54 because exogenous NT3 reduced the number of pyknotic nuclei without significantly altering prolifera

55 nsistent with apoptosis (shrunken cells with pyknotic nuclei); (3) DNA laddering which can be blocked

56 tic DNA fragmentation, thionine staining for pyknotic nuclei, silver staining for degenerating cells,

57 A relative increase in pyknotic nuclei, sub-GI cytometry counts and caspase act

58 , as indicated by decreases in the number of pyknotic nuclei, terminal deoxynucleotidyltransferase-me

59 For pyknotic nuclei, the very high local concentration of DN

60 Furthermore, pyknotic O4+ OLs were double-labeled with 4-HNE.

61 [bromodeoxyuridine (BrdU)-labeled] or dying (pyknotic or terminal deoxynucleotidyl transferase-mediat

62 early ages, and a relatively slow removal of pyknotic PR nuclei.

63 s of erythropoiesis, including the terminal, pyknotic stage.

64 lei in a completely inactive and contracted (pyknotic) state, and of nuclei of actively dividing cell

65 Similarly, the ratio of pyknotic to normal neurons peaked between days 0-3 in ma

66 Subsequently, pyknotic, TUNEL-positive cells were also localized to th