ライフサイエンスコーパス: pyrogenic

1 IL-18 i.p. or i.c.v. is not pyrogenic.

2 ty although in general the mutants were less pyrogenic.

3 We asked whether PAF possesses pyrogenic activity (Expt 1) and mediates LPS fever (Expt

4 administered intranasally at 400 mug with no pyrogenic activity, but as little as 0.03 mug/kg of body

5 In rabbits, ETB was moderately pyrogenic and enhanced susceptibility to lethal shock, w

6 ical properties of the ETs, particularly the pyrogenic and lethal activities of ETB not shared by ETA

7 Purified SpeL and SpeM were pyrogenic and mitogenic for rabbit splenocytes and human

8 SpeK and SSA were pyrogenic and toxic for rabbits.

9 The best-characterized group of SAGs are the pyrogenic bacterial SAGs, which utilize a high degree of

10 ly released during systemic inflammation, is pyrogenic by binding to IL-6Ralpha on brain endothelial

11 engineered carbon nanoparticles and natural pyrogenic carbon (char) are unknown.

12 Ubiquitous in the environment, pyrogenic carbon (PyC) arises from incomplete combustion

13 ds (BPCA) are molecular markers specific for pyrogenic carbon (PyC) which can provide information on

14 Pyrogenic carbon (PyC), produced naturally (wildfire cha

15 The production of pyrogenic carbon (PyC; a continuum of organic carbon (C)

16 Pyrogenic carbon is widespread in soil due to wildfires,

17 However, the electrochemical properties of pyrogenic carbon matrices and the kinetic preference of

18 s contribute to the overall electron flux of pyrogenic carbon to a lesser extent with greater pyrolys

19 Here we show that environmentally relevant pyrogenic carbon with average H/C and O/C ratios of less

20 This review focuses on low-cost pyrogenic carbon, activated carbon (AC), and metal-carbo

21 Biochar, a form of pyrogenic carbon, can contribute to agricultural and env

22 constitute major electroactive components in pyrogenic carbon.

23 l for metal oxide ENM, with nanoparticles of pyrogenic carbonaceous material (n-PCM) derived from pec

24 he pi electron-rich, polyaromatic surface of pyrogenic carbonaceous materials (PCMs) (i.e., biochar,

25 Pyrogenic carbonaceous matter (PCM) includes environment

26 stablished when focusing specifically on the pyrogenic class of compounds.

27 how that vascular plant-derived aromatic and pyrogenic compounds were preferentially retained, wherea

28 ome complex, which leads to secretion of the pyrogenic cytokine IL-1beta.

29 produced interleukin-6, an inflammatory and pyrogenic cytokine, in a p38 MAPK-dependent fashion.

30 Fever is thought to be initiated by pyrogenic cytokines inducing the production of prostagla

31 increases of intraperitoneal neutrophils and pyrogenic cytokines were recorded.

32 did induce fever when co-injected with a non-pyrogenic dose (when given alone) of IL-1beta, and exace

33 of IL-1beta, and exacerbated the fever to a pyrogenic dose of IL-1beta.

34 increase thermogenesis in response to a low, pyrogenic dose of LPS (10 mug/kg, i.v.).

35 Because PGE2 mediates the pyrogenic effect of IL-1beta, these effects might be esp

36 in the striatum can be dissociated from its pyrogenic effects on body temperature.

37 Streptococcal pyrogenic enterotoxin C (Spe-C) is a superantigen virule

38 coccal enterotoxin type B, and streptococcal pyrogenic enterotoxin types A and C to induce inflammato

39 ococcal virulence factors, the streptococcal pyrogenic exotoxin (Spe) A and the cysteine protease Spe

40 Streptococcal pyrogenic exotoxin (Spe) B, a streptococcal cysteine pro

41 the emm1.0 allele and the same streptococcal pyrogenic exotoxin (Spe) genotype, speA(+) speB(+) speC

42 S supernatants and recombinant streptococcal pyrogenic exotoxin A (rSpeA), suggesting that the presen

43 an-GAS interactions, including streptococcal pyrogenic exotoxin A (scarlet fever toxin) and two uncha

44 Streptococcal pyrogenic exotoxin A (SPE A) is secreted by some strains

45 the sequenced M1 SF370 strain: streptococcal pyrogenic exotoxin A (SpeA) and a streptodornase D (SdaD

46 ibute to pathogenesis, such as streptococcal pyrogenic exotoxin A (SpeA) and SpeK, streptococcal supe

47 terotoxins of S. aureus and to streptococcal pyrogenic exotoxin A (SpeA) and streptococcal superantig

48 e bacterial superantigen (SAg) streptococcal pyrogenic exotoxin A (SpeA) could be simulated, as deter

49 coccal enterotoxin B (SEB) and streptococcal pyrogenic exotoxin A (SPEA) delivered through the intran

50 stered intravenously, SEC1 and streptococcal pyrogenic exotoxin A (SPEA) did not cause symptoms when

51 d production of immunoreactive streptococcal pyrogenic exotoxin A (SpeA) increased.

52 Streptococcal pyrogenic exotoxin A (SpeA) is a superantigen produced b

53 ces the bacterial superantigen streptococcal pyrogenic exotoxin A (SpeA) is associated with outbreaks

54 ated with STSS usually produce streptococcal pyrogenic exotoxin A (SpeA), a bacterial superantigen ca

55 te the bacterial superantigen, streptococcal pyrogenic exotoxin A (SPEA), in the pathogenesis of necr

56 ainst the Vbeta8-targeting SAg streptococcal pyrogenic exotoxin A (SpeA), or active immunization with

57 gments lymphocyte responses to streptococcal pyrogenic exotoxin A (SPEA).

58 uisition of prophages encoding streptococcal pyrogenic exotoxin A and extracellular DNases and (2) th

59 sa to allow for penetration of streptococcal pyrogenic exotoxin A and possibly viable streptococci.

60 ried significant virulence factors including pyrogenic exotoxin A and streptococcal superantigen.

61 (TSS) toxin 1 (TSST-1) and the streptococcal pyrogenic exotoxin A as low as 10 pg/ml.

62 Production of streptococcal pyrogenic exotoxin A by Streptococcus pyogenes was unaff

63 centration of the superantigen streptococcal pyrogenic exotoxin A from 90.9 +/- 12.7 ng/mL with the c

64 reaction amplification of the streptococcal pyrogenic exotoxin A gene.

65 Superantigens such as pyrogenic exotoxin A interact with monocytes and T lymph

66 ing the bacterial superantigen streptococcal pyrogenic exotoxin A is often found in streptococcal str

67 Streptococcal pyrogenic exotoxin A levels at 9 hrs were 19.9 ng/mL in

68 ined difference in circulating streptococcal pyrogenic exotoxin A levels between the groups.

69 nantly M types 1 and 3, which produce either pyrogenic exotoxin A or B or both.

70 c toxin superantigens (PTSAgs) streptococcal pyrogenic exotoxin A or C (SPE A or C), although cases h

71 oding the SpeA1 variant of the streptococcal pyrogenic exotoxin A superantigen.

72 ccus pyogenes that (along with streptococcal pyrogenic exotoxin A) is highly associated with streptoc

73 ction of erythrogenic toxin A (also known as pyrogenic exotoxin A).

74 factors, including Sic, SpeB, streptococcal pyrogenic exotoxin A, Mac protein, and streptococcal pho

75 xic shock syndrome toxin-1 and streptococcal pyrogenic exotoxin A, respectively, across porcine vagin

76 3 h after intravenous infusion of M type 3, pyrogenic exotoxin A-producing group A streptococci.

77 vely, of the prophage encoding streptococcal pyrogenic exotoxin A.

78 t encodes the SpeA4 variant of streptococcal pyrogenic exotoxin A.

79 ted cysteine protease known as streptococcal pyrogenic exotoxin B (SpeB) is a key virulence factor th

80 Streptococcal pyrogenic exotoxin B (SpeB) is a protease secreted by gr

81 Streptococcal pyrogenic exotoxin B (SpeB) is an extracellular cysteine

82 The streptococcal pyrogenic exotoxin B (SpeB) is an important virulence fa

83 Streptococcal pyrogenic exotoxin B (SpeB), a conserved cysteine protea

84 of the extracellular protease, streptococcal pyrogenic exotoxin B (SpeB), capsular hyaluronic acid, a

85 xtracellular toxins, including streptococcal pyrogenic exotoxin B (SpeB), have been implicated in pat

86 ptolysin S (SLS) and speB, the gene encoding pyrogenic exotoxin B (SpeB).

87 lar cysteine protease known as streptococcal pyrogenic exotoxin B (SpeB).

88 ibitor of complement (Sic) and streptococcal pyrogenic exotoxin B (SpeB).

89 nd exotoxins, e.g., streptolysin S (SLS) and pyrogenic exotoxin B (SpeB).

90 tracellular cysteine protease [streptococcal pyrogenic exotoxin B (SpeB)] that is a critical virulenc

91 tococcal erythrogenic toxin B (streptococcal pyrogenic exotoxin B [SPE B]) by Streptococcus pyogenes

92 toxin B (SPE B), also known as streptococcal pyrogenic exotoxin B and streptococcal proteinase.

93 ptococcal plasmin receptor and streptococcal pyrogenic exotoxin B are currently considered major puta

94 Streptococcal pyrogenic exotoxin B is a highly conserved precursor of

95 ology and infection pattern of streptococcal pyrogenic exotoxin B-positive (SpeB(+)) and SpeB-negativ

96 s, including the hyaluronic acid capsule and pyrogenic exotoxin B.

97 Streptococcal pyrogenic exotoxin C (SPE C) is a superantigen produced

98 The cocrystal structure of streptococcal pyrogenic exotoxin C (SPE C) with HLA-DR2a (DRA*0101,DRB

99 We report the structure of streptococcal pyrogenic exotoxin C (SPE-C) complexed with HLA-DR2a (DR

100 o be the bacteriophage-encoded streptococcal pyrogenic exotoxin C (SpeC).

101 s well as the phage-associated streptococcal pyrogenic exotoxin C (SpeC).

102 scarlet fever toxin) and two uncharacterized pyrogenic exotoxin homologues, all phage-associated.

103 ion of a novel exotoxin termed streptococcal pyrogenic exotoxin J (SPE J).

104 induced the prophage encoding streptococcal pyrogenic exotoxin K (SpeK) and extracellular phospholip

105 isolated are M types 1 and 3, which produce pyrogenic exotoxin type A.

106 nd streptococcal superantigen, streptococcal pyrogenic exotoxin.

107 eptococcal superantigen (ssa), streptococcal pyrogenic exotoxins (speC, speH, and speI), and DNases (

108 Streptococcal pyrogenic exotoxins (SPEs) are superantigens that have b

109 The streptococcal pyrogenic exotoxins (Spes) play a central role in the pa

110 (complement C5a peptidase), or speB or speC (pyrogenic exotoxins B and C).

111 The pyrogenic exotoxins of group A streptococci and staphylo

112 secreted GAS SAgs, namely the streptococcal pyrogenic exotoxins produced by the globally disseminate

113 genic activity elicited by the streptococcal pyrogenic exotoxins SpeB and SpeC, as well as by GAS cul

114 ive GAS isolate or by purified streptococcal pyrogenic exotoxins, increased in plasma following IVIG

115 ge-associated genes (speA and speC) encoding pyrogenic exotoxins.

116 re supernatants or by purified streptococcal pyrogenic exotoxins.

117 showed no homology with known Streptococcus pyrogenic exotoxins.

118 syndrome toxin-1 (TSST-1), and streptococcal pyrogenic exotoxins] and anthrax toxin are bioterrorism

119 For pyrogenic HA, a more than 10-fold increase in dissolved

120 response, but the mechanism by which IL-6 is pyrogenic has remained obscure.

121 ind, based on measurements over Africa, that pyrogenic HCOOH:CO enhancement ratios are much higher th

122 Pyrogenic humic acid has been included in our study sinc

123 ta, and interleukin (IL)-18, a member of the pyrogenic IL-1 beta family.

124 This model assumes that TOC in pyrogenic-impacted areas sorbs similarly to coal tar, ra

125 A protein in culture supernatants was pyrogenic in rabbits, was mitogenic for splenocytes, and

126 onary phase are described for the removal of pyrogenic lipopolysaccharides (LPS) from insulin.

127 haride by Kupffer cells, the major source of pyrogenic mediators.

128 IL)-1beta and IL-6 are thought to convey the pyrogenic message to the brain region where fever is reg

129 nd (2) direct transmission to the POA of the pyrogenic messages via peripheral (largely vagal) affere

130 PAH ratios for these samples suggest pyrogenic (not petrogenic) contamination - indicating po

131 s to the soil are substituted with inputs of pyrogenic organic matter (py-OM).

132 lization of soil organic carbon (SOC), added pyrogenic organic matter (PyOM) and root respiration.

133 l in the global C cycle, and the addition of pyrogenic organic matter (PyOM) has been shown to change

134 ity is central to elucidating the role(s) of pyrogenic organic matter (PyOM) in biogeochemical cycles

135 also convert part of the burnt biomass into pyrogenic organic matter (PyOM).

136 s showed a 50% decrease in the proportion of pyrogenic PAH derived from fossil fuel combustion over t

137 enic PAHs were similar in magnitude to total pyrogenic PAH fluxes in early 1900, suggesting that thes

138 Pyrogenic PAH fluxes to sediments were observed to conti

139 total in petroleum-derived PAHs and in some pyrogenic PAH mixtures.

140 in concentrations and radiocarbon content of pyrogenic PAHs and perylene were determined 20 years aft

141 Fluxes of pyrogenic PAHs related to biomass burning were consisten

142 Radiocarbon analysis of pyrogenic PAHs showed a 50% decrease in the proportion o

143 Fluxes of biomass-derived pyrogenic PAHs were similar in magnitude to total pyroge

144 s of the hypothalamus, but the origin of the pyrogenic PGE2 has not been clearly determined.

145 The cellular source for pyrogenic PGE2 remains a subject of debate; several hypo

146 methylated (petrogenic) versus unmethylated (pyrogenic) phenanthrenes; such antibodies will be useful

147 The most pyrogenic preoptic sites were clustered along the ventro

148 the role of interleukin-1beta, (IL-1beta), a pyrogenic, proinflammatory cytokine, in FS.

149 er S. liquefaciens bloodstream infections or pyrogenic reactions occurred at this hemodialysis facili

150 ia liquefaciens bloodstream infections and 6 pyrogenic reactions occurred in outpatients at a hemodia

151 oodstream infections, and in 8, patients had pyrogenic reactions without bloodstream infection.

152 ed S. liquefaciens bloodstream infections or pyrogenic reactions.

153 5 mug administered intramuscularly induced a pyrogenic response.

154 luded that PAF is a highly potent endogenous pyrogenic substance and a mediator of LPS fever.

155 oneally with staphylococcal enterotoxin B, a pyrogenic superantigen, and their inflammatory responses

156 e a molecular basis for the development of a pyrogenic threshold as individuals acquire immunity to c

157 s a member of the new subfamily (group V) of pyrogenic toxin superantigens (PTSAgs) and examined its

158 cal STSS cases have been associated with the pyrogenic toxin superantigens (PTSAgs) streptococcal pyr

159 us aureus and Streptococcus pyogenes express pyrogenic toxin superantigens (PTSAgs) that are associat

160 d Streptococcus pyogenes produce a family of pyrogenic toxin superantigens (PTSAgs) that can cause il

161 treptococcal and staphylococcal origins, the pyrogenic toxin superantigens (PTSAgs).

162 The data demonstrate that SpeL and SpeM are pyrogenic toxin superantigens and suggest that they may

163 The pyrogenic toxin toxic shock syndrome toxin-1 from Staphy

164 es that encode a variety of immunomodulatory pyrogenic toxins (PTs), including the staphylococcal ent

165 The strong structural homology between the pyrogenic toxins and other bacterial proteins suggests t