ライフサイエンスコーパス: pyrrolidine dithiocarbamate

1 stress protein response with geldanamycin or pyrrolidine dithiocarbamate.

2 ally inhibited with the NF-kappaB antagonist pyrrolidine dithiocarbamate.

3 essed by the antioxidant NF-kappaB inhibitor pyrrolidine dithiocarbamate.

4 ted by the antioxidants N-acetylcysteine and pyrrolidine dithiocarbamate.

5 acetylcysteine, TEMPO, dihydrolipoic acid or pyrrolidine dithiocarbamate.

6 y antioxidants, N-acetyl-L-cysteine (NAC) or pyrrolidine dithiocarbamate.

7 )H oxidase inhibitors, N-acetylcysteine, and pyrrolidine dithiocarbamate].

8 on of nuclear factor kappa B (NF kappa B) by pyrrolidine dithiocarbamate (200 microM), dexamethasone

9 Pretreatment of rats with pyrrolidine dithiocarbamate (50, 100, and 200 mg/kg, i.p

10 osyl-l-phenylalanine chloromethyl ketone and pyrrolidine dithiocarbamate, abrogate CD40-induced Smad7

11 nuclear factor kappaB (NF-kappaB) inhibitor pyrrolidine dithiocarbamate also inhibited NOS2 expressi

12 Pyrrolidine dithiocarbamate also markedly reduced the LP

13 The antioxidant pyrrolidine dithiocarbamate also suppressed constitutive

14 Pyrrolidine dithiocarbamate (an antioxidant inhibitor of

15 Pyrrolidine dithiocarbamate, an antioxidant that acts as

16 Pyrrolidine dithiocarbamate, an antioxidant, inhibited t

17 ysteine, a precursor of glutathione, but not pyrrolidine dithiocarbamate, an inhibitor of NF-kappaB a

18 ibited lactate dehydrogenase release, and by pyrrolidine dithiocarbamate, an inhibitor of NF-kappaB.

19 Application of pyrrolidine dithiocarbamate, an inhibitor of nuclear fac

20 Treatment of MDA-MB-231 cells with pyrrolidine dithiocarbamate, an inhibitor of p65, or sma

21 n-regulation was suggested by the ability of pyrrolidine dithiocarbamate, an inhibitor of the NFkappa

22 , palmitate-induced apoptosis was blocked by pyrrolidine dithiocarbamate and 4,5-dihydroxy-1,3-benzen

23 ultraviolet B and hydrogen peroxide whereas pyrrolidine dithiocarbamate and butyl hydroxyanisole are

24 NF-kappaB inhibitors, pyrrolidine dithiocarbamate and curcumin, prevented the

25 on of these genes; and (iv) the antioxidants pyrrolidine dithiocarbamate and ebselen abolish transcri

26 o effectively suppressed by the antioxidants pyrrolidine dithiocarbamate and glutathione peroxidase.

27 addition of inhibitors to either NF kappa B (pyrrolidine dithiocarbamate and N-acetyl-l-cysteine) or

28 t were prevented by NF-kappaBeta inhibitors (pyrrolidine dithiocarbamate and SN-50), silencing of p65

29 pretreatment with two NF-kappaB inhibitors, pyrrolidine dithiocarbamate and the proteasome inhibitor

30 cetylcysteine, butylated hydroxyanisole, and pyrrolidine dithiocarbamate and was partially attenuated

31 as inhibited in the presence of antioxidant (pyrrolidine dithiocarbamate) and Ca2+ chelators (BAPTA-A

32 pounds including interferonbeta1, ribavirin, pyrrolidine dithiocarbamate, and fluoxetine were tested

33 cells with membrane-permeable antioxidants, pyrrolidine dithiocarbamate, and N-acetylcysteine abroga

34 ants such as superoxide dismutase, catalase, pyrrolidine dithiocarbamate, and N-acetylcysteine.

35 cked by the antioxidant N-acetyl-L-cysteine, pyrrolidine dithiocarbamate, and the NADPH oxidase inhib

36 pplied for the extraction of Se(IV)-ammonium pyrrolidine dithiocarbamate (APDC) complex followed by S

37 ised in the presence of Sb(III) and ammonium pyrrolidine dithiocarbamate (APDC) using styrene as the

38 to the antioxidants N-acetyl L-cysteine and pyrrolidine dithiocarbamate, as well as to overexpressio

39 ly, the antioxidant and NF-kappa B inhibitor pyrrolidine dithiocarbamate blocked doxorubicin-induced

40 mentation was sensitive to cycloheximide and pyrrolidine dithiocarbamate, but not to dexamethasone or

41 -induced Cox-2 was sensitive to antioxidant (pyrrolidine dithiocarbamate), Ca(2+) chelator (BAPTA-AM)

42 -2 activities were sensitive to antioxidant (pyrrolidine dithiocarbamate), Ca(2+) chelator 1,2-bis(am

43 ited endotoxin-induced NF-kappaB activation, pyrrolidine dithiocarbamate did not affect p38 phosphory

44 on in HEp2 but not in DRHEp2 and antioxidant pyrrolidine dithiocarbamate eliminated docetaxel-induced

45 oM, respectively) compared to clioquinol and pyrrolidine dithiocarbamate (IC50 of 10 and 20 microM),

46 ioxidant inhibitor of NF-kappa B activation, pyrrolidine dithiocarbamate, in wild-type and NF-kappa B

47 Although the antioxidant pyrrolidine dithiocarbamate increased the activity of pu

48 Pyrrolidine dithiocarbamate inhibited both chemokine gen

49 Antioxidants N-acetylcysteine and pyrrolidine dithiocarbamate inhibited MMP production by

50 Preincubation with pyrrolidine dithiocarbamate inhibited the induction, ind

51 issimilar antioxidants, N-acetyl cysteine or pyrrolidine dithiocarbamate, markedly attenuated both st

52 The NF-kappaB inhibitors curcumin, pyrrolidine dithiocarbamate or CAY10512 abrogated both I

53 he constitutive activation of NF-kappaB with pyrrolidine dithiocarbamate or expression of IkappaBalph

54 eramide, and was attenuated by the inhibitor pyrrolidine dithiocarbamate or following transient trans

55 cell line MO7/p210 with the reducing agents pyrrolidine dithiocarbamate or N-acetylcysteine reduced

56 ted by NAC and DPI as well as an antioxidant pyrrolidine dithiocarbamate or reduced glutathione (GSH)

57 Pretreatment with pyrrolidine dithiocarbamate or sulfasalazine attenuated

58 ted hydroxyanisole, N-acetyl-L-cysteine, and pyrrolidine dithiocarbamate, or by the H2O2-degrading en

59 mg/kg p.o. daily), or an antioxidant, either pyrrolidine dithiocarbamate (PDTC) (200 mg/kg s.c. daily

60 l or treatment of cells with the antioxidant pyrrolidine dithiocarbamate (PDTC) also reduces intracel

61 hich was reversed by the NF-kappaB inhibitor pyrrolidine dithiocarbamate (PDTC) and by NF-kappaB sile

62 Pyrrolidine dithiocarbamate (PDTC) blocked activation of

63 The cell permeable antioxidant pyrrolidine dithiocarbamate (PDTC) decreased the intrace

64 ough previous studies have demonstrated that pyrrolidine dithiocarbamate (PDTC) exerts protection aga

65 The antioxidant pyrrolidine dithiocarbamate (PDTC) greatly diminished th

66 Pyrrolidine dithiocarbamate (PDTC) is a thiol compound w

67 Pyrrolidine dithiocarbamate (PDTC) is an inhibitor of NF

68 ied the effects of two NF-kappaB inhibitors (pyrrolidine dithiocarbamate (PDTC) or BAY11-7082 (BAY)),

69 utant IkappaBalpha or pharmacologically with pyrrolidine dithiocarbamate (PDTC) prevented cytokine, b

70 G2 cells to beta-naphthoflavone (beta-NF) or pyrrolidine dithiocarbamate (PDTC) resulted in the up-re

71 etatarsal bones in the presence of GH and/or pyrrolidine dithiocarbamate (PDTC), a known NF-kappaB in

72 tured rat metatarsal bones with IGF-I and/or pyrrolidine dithiocarbamate (PDTC), a known NF-kappaB in

73 lines (SH-EP1 and SK-N-AS) were treated with pyrrolidine dithiocarbamate (PDTC), a NFkappaB inhibitor

74 Pyrrolidine dithiocarbamate (PDTC), a presumed antioxida

75 expression occurs in the presence of either pyrrolidine dithiocarbamate (PDTC), a selective inhibito

76 n this study, we investigated the ability of pyrrolidine dithiocarbamate (PDTC), an agent that inhibi

77 Treatment of cells with pyrrolidine dithiocarbamate (PDTC), an antioxidant that

78 Pyrrolidine dithiocarbamate (PDTC), an inhibitor of NF-k

79 The oxidant scavenger, pyrrolidine dithiocarbamate (PDTC), inhibited iNOS expre

80 In the presence of antioxidants [pyrrolidine dithiocarbamate (PDTC), N-acetyl l-cysteine

81 of ROS in leukemia cells by the antioxidants pyrrolidine dithiocarbamate (PDTC), N-acetylcysteine (NA

82 Following stimulation with TNF-alpha, pyrrolidine dithiocarbamate (PDTC), N-acetylcysteine, an

83 3 inhibitor, z-DEVD-CH2F, and an antioxidant pyrrolidine dithiocarbamate (PDTC), whereas cytochrome c

84 that the addition of an antioxidant, such as pyrrolidine dithiocarbamate (PDTC), would attenuate HO-1

85 by antioxidants N-acetyl cysteine (NAC) and pyrrolidine dithiocarbamate (PDTC).

86 econd group (n=6) injected with two doses of pyrrolidine dithiocarbamate (PDTC, 100 mg/kg, i.p.) 24 a

87 treated with IFN-gamma and supplemented with pyrrolidine dithiocarbamate (PDTC, an NF-kappaB inhibito

88 e (7-NI, specific nNOS inhibitor), 3) 7-NI + pyrrolidine dithiocarbamate (PDTC, NF-kappaB inhibitor),

89 The potent inhibitor of NF-kappaB, pyrrolidine dithiocarbamate (PDTC; 250 mg/kg s.c.) was a

90 teasome inhibitor MG-132 and the antioxidant pyrrolidine-dithiocarbamate (PDTC)-prevented poly IC + I

91 Preincubation of HUVECs with pyrrolidine dithiocarbamate prevented MAC-induced increa

92 ells with three unrelated scavengers of ROS, pyrrolidine dithiocarbamate, pyruvate, or nordihydroguai

93 p38 and NF-kappaB activation by SB203580 and pyrrolidine dithiocarbamate, respectively, blocked endot

94 ependent VCAM-1 transcription with 50 microM pyrrolidine dithiocarbamate resulted in 87.7% inhibition

95 d that TNF activates NF-kappa B through both pyrrolidine dithiocarbamate-sensitive and -insensitive m

96 reporter gene led to cisplatin-inducible and pyrrolidine dithiocarbamate-sensitive luciferase activit

97 nhibitors of NF-kappaB (N-acetylcysteine and pyrrolidine dithiocarbamate) suggest that the stimulator

98 Pyrrolidine dithiocarbamate was tested for effects on ch

99 Pyrrolidine dithiocarbamate was unable to inhibit ultrav

100 = 2-(diisopropylphosphino)ethanethiol; L1 = pyrrolidine dithiocarbamate) was determined by HPLC comp

101 An antioxidant, pyrrolidine dithiocarbamate, which blocked LPS-induced N

102 -activated reporter gene could be blocked by pyrrolidine dithiocarbamate, which is known to inhibit N

103 Treatment with the antioxidant pyrrolidine dithiocarbamate, which is known to inhibit N