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1 ing tRNA, it influences decoding of the UAGA quadruplet.
2 activated concomitantly by spike triplets or quadruplets.
3 dual log likelihoods of composing amino acid quadruplets.
4 allow decoding of complementary 5'-CAAA(-3') quadruplets.
6 oup of 83 women carrying twins, triplets, or quadruplets (aged 20-46 y) was recruited from 2011 to 20
8 s the codon immediately 5' of the first UAGA quadruplet, and release factor 1 is partially inactivate
10 plets as codons, the decoding of tandem UAGA quadruplets by an engineered tRNA(Leu) with an eight-bas
13 frameshift sequence) in the A site, and this quadruplet "codon-anticodon" helix is translocated to th
15 ibo-Q1) that efficiently decodes a series of quadruplet codons and the amber codon, providing several
16 ly encoded in response to unique triplet and quadruplet codons including fluorescent, photoreactive a
17 ral amino acids into proteins in response to quadruplet codons, and the creation of an orthogonal tra
18 dology for incorporating UAAs in response to quadruplet codons, but currently, it is mostly limited t
19 As ribo-Q1 independently decodes a series of quadruplet codons, this work provides foundational techn
23 scoring function (log likelihoods of residue quadruplet compositions) is derived by the analysis of a
24 n facilitated by the evolution of orthogonal quadruplet decoding ribosomes and the discovery of mutua
26 anslation system that uses amber and evolved quadruplet-decoding transfer RNAs to encode numerous pai
27 etween sequence pairs, but between triplets, quadruplets, etc., is proposed to strengthen the proper
29 ic mutagenesis of both suprabranch guanosine quadruplets (G(4)) revealed a key role of central G resi
31 tity of the codon immediately 5' of the UAGA quadruplet influences the efficiency of quadruplet trans
32 , and we identified two frequently occurring quadruplet marks 'K9me1K23acK27me2K36me2' and 'K9me3K23a
34 re than 10 years ago, include the processing quadruplet motif (PQM) and the inverted processing quadr
37 the m1G37 modification in the controversial quadruplet-pairing model of tRNA frameshift suppressors.
38 te of the 4-AzHBA probe was localized to the quadruplet Phe(90)-Met(91)-Val(92)-Phe(93) using ESI LC-
41 stages of rediploidization were identified: quadruplets retaining their ancestral tetraploid conditi
42 l inactivation of release factor 1, the UAGA quadruplet specifies a leucine residue with an efficienc
43 g their ancestral tetraploid condition, semi-quadruplets still reflecting the ancestral tetraploidy w
45 UAGA quadruplet influences the efficiency of quadruplet translation via the properties of its cognate
46 previous model that suppressor tRNAs induce quadruplet translocation now appears incorrect for most,
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