ライフサイエンスコーパス: quality control

1 r its effects on glial viability and protein quality control.

2 ventually be applied in routine analyses for quality control.

3 closely associated with protein folding and quality control.

4 ns in energetics, membrane organization, and quality control.

5 ck key identification steps and perform data quality control.

6 SUMOylation participates in cellular protein quality control.

7 often feature more stringent protein and DNA quality control.

8 ions characterized by impaired mitochondrial quality control.

9 rough its role in mitochondrial turnover and quality control.

10 olves protein degradation pathways to ensure quality control.

11 shed, we analyzed 20 in 14 genes that passed quality control.

12 constitutes a critical step of mitochondrial quality control.

13 tal of 34,874 SNPs remained per animal after quality control.

14 e widely used for sensing, communication and quality control.

15 l cord blood and retained 394,460 loci after quality control.

16 thod to be specific and suitable for saffron quality control.

17 perone contributing to mitochondrial protein quality control.

18 actors contribute to cotranslational protein quality control.

19 terization of mAbs to ensure their stringent quality control.

20 omplex networks of mitochondrial defense and quality control.

21 e that this method is suitable for regulated quality control.

22 gnostic density plots further allow for some quality control.

23 based on 20 individuals following extensive quality control.

24 d and cytosolic chaperone systems in protein quality control.

25 ed, interpretable, automatable, and scalable quality control.

26 ation of energy metabolism and mitochondrial quality control.

27 vely analyze the data may also be applied in quality control.

28 the expression of many genes involved in ER quality control.

29 s of the PINK1/parkin-mediated mitochondrial quality control.

30 Raw data were obtained from the authors and quality controlled.

31 s Disease Centre Discovery Cohort and, after quality control, 228 exomes were available for analyses.

32 After quality control, 780 samples with phenotype and covariat

33 the Caulobacter bacterial cell cycle and the quality control adaptor SspB.

34 nisms of the VHHs and their potential use as quality control agents for the end game of poliovirus er

35 results reveal new roles for Tom1 in protein quality control, aggregate prevention, and, therefore, p

36 industries and regulatory agencies for food quality control, allowing detecting frauds and enabling

37 of protocols and can serve as standards for quality control and analyses.

38 roughput experiments pose a number of unique quality control and analysis challenges.

39 ated with generating automated pipelines for quality control and analysis of rare variants; the impor

40 processes, a lack of standardized curation, quality control and analysis procedures have hindered ex

41 release by infected CD4+ T cells on protein quality control and autophagy in cardiomyocytes.

42 f upfront training, human error with limited quality control and batch-to-batch variations.

43 equestration plays a central role in protein quality control and cellular fitness and represents a cr

44 a computational pipeline that automates the quality control and data analyses of ChIP-seq and DNase-

45 sts to provide comprehensive alignment-based quality control and error profile analysis--something th

46 ng long 3'UTRs to perform dual roles in mRNA quality control and gene expression regulation.

47 METHOD: Following uniform quality control and imputation procedures using the 1000

48 estigating substitutions and might assist in quality control and increase food safety for consumers.

49 Here we review recent advances on RNA quality control and its role in the suppression of RNA s

50 A-beta in maintaining neuronal mitochondrial quality control and neuronal physiology.

51 tion software pipeline (YARN), that includes quality control and preprocessing, gene filtering, and n

52 It is currently unclear how quality control and protein degradation systems coordina

53 ans play crucial biological roles in protein quality control and recognition events.

54 d sensor is applicable to clinical analysis, quality control and routine determination of drugs in ph

55 xternal calibration procedures, and internal quality control and standards are analyzed in each run.

56 arge RNA-Seq data sets requires both careful quality control and the need to account for sparsity due

57 coexpression data set was generated based on quality controlled and normalized public data, and used

58 This includes a stepwise system of quality controls and user-friendly data presentation pla

59 of mitochondrial dynamics and mitochondrial quality control, and disturbed cellular interorganellar

60 strains recommended for use in diagnosis and quality control, and hence serves as a valuable cross-pl

61 iteria for product homogeneity, potency, and quality control, and may exhibit a distinctive immunolog

62 s, developing improved nutritional products, quality control, and milk product authentication.

63 scopy to diagnostic screening, metabolomics, quality control, and other high-throughput applications

64 NEFs, helped fine-tune mitochondrial protein quality control, and regulated crucial mtHsp70 functions

65 rform information compression, comprehensive quality controls, and biological information retrieval i

66 the speed and efficiency of performing data quality control, annotation, and association analysis.

67 rt of the data analysis, several statistical quality control approaches were evaluated to detect inac

68 al and molecular mechanisms of mitochondrial quality control are described in detail, physiological o

69 Impaired mitochondria dynamics and quality control are involved in mitochondrial dysfunctio

70 ly, our data suggest that NGD and subsequent quality control are triggered by ribosome collision.

71 Protocols and quality controls are given for the following: 1) extract

72 gkg(-1), significant in legislative and fish quality control aspects, PLS regression model based on s

73 lization track generation, and (5) extensive quality control assessment.

74 Quality-control assessments of [CO3(2-)]spec data obtain

75 ty and the mechanistic principles of protein quality control assisted by chaperones.

76 n a comprehensive workflow covering sequence quality control, automated sgRNA sequence extraction, al

77 Our data supports the notion that basal quality control autophagy and vimentin cage clearance in

78 s, for device design, stability studies, and quality control because the desired nanostructures are o

79 Connections not only ensure quality control but also fine-tune the gene expression p

80 standing the molecular basis of glycoprotein quality control but has been hampered by the lack of sui

81 Diligent analysis and quality control can require multiple computational tools

82 rates at a level compatible with the protein quality-control capacity of the cell.

83 ERGIC may play an underappreciated role as a quality-control center for mutant and/or malformed membr

84 zyme acts as the single glycoprotein folding quality control checkpoint: it selectively reglucosylate

85 This aaRS proofreading provides quality control checkpoints that exclude non-cognate ami

86 ng but unspliced M1 mRNA bypasses the normal quality-control checkpoints.

87 it site we termed intramitochondrial protein quality control compartment (IMiQ).

88 The Ribosome-associated Quality control Complex (RQC) engages stalled ribosomes

89 talling leads to recruitment of the ribosome quality control complex (RQC), which targets the partial

90 domain within Vms1 that allows this protein quality control component to specifically recognize dama

91 rom healthy controls) that met published OCT quality control criteria and were suitable for meta-anal

92 A sample of 519 youths who met quality control criteria entered analysis, of whom 25 (4

93 The main features of the algorithm are quality control criteria to detect failed runs, ensuring

94 folding sensor in the calnexin/calreticulin quality control cycle that is known to regenerate the Gl

95 by showing that under basic forms of active quality control, discrepancies between the outputs of th

96 Chaperone-mediated autophagy (CMA) serves as quality control during stress conditions through selecti

97 C8 as a previously unknown Hsp70-independent quality control E3 ligase for hERG.

98 Thus, UBE2O is a self-contained quality control factor that comprises substrate recognit

99 periplasmic chaperones function primarily as quality-control factors; this function complements the f

100 for cell line authentication, annotation and quality control fall short addressing genetic heterogene

101 After quality control filters and GWAS imputation, 285 patient

102 comprehensive set of analysis functions for quality control, filtration, annotation, pathogenic pred

103 In addition, there has been a lack of quality control for herbal preparations.

104 fferent ChIA-PET protocols and also provides quality controls for different steps of ChIA-PET analysi

105 These data show that the quality control function of IleRS is required in B. subt

106 diverted from their normal cellular protein quality control function to play similar roles during vi

107 ins suggest a molecular chaperone or protein quality control function.

108 ed/mutant/misfolded proteins, which serves a quality-control function.

109 ss response genes, such as the mitochondrial quality control gene, Park2.

110 data generated by NGS platforms necessitate quality control, genome assembly and sequence similarity

111 tion of pathways that regulate mitochondrial quality control have been linked to neurodegenerative di

112 ance mechanisms, however, the details of RNA quality control have not been extensively characterised

113 ed active THz device, for pharmaceutical and quality control imaging of macroscopic samples, in real-

114 pretation that includes mutation mapping and quality control, impact prediction and extensive annotat

115 The new radio-TLC method allows quality control in a short time using a fast, reliable,

116 in an attractive alternative for corn syrups quality control in industries and official laboratories.

117 ncreasingly recognized role of mitochondrial quality control in neurodegenerative diseases, these stu

118 , suggesting a requirement for mitochondrial quality control in regenerating myocardium.

119 rge-scale datasets and will help standardize quality control in the field.

120 elationship between inflammation and protein quality control in the heart is not well understood.

121 The loss of aminoacylation quality control in the ileS(T233P) strain resulted in th

122 studied the role of Parkin on mitochondrial quality control in vivo by knocking out Parkin in the PD

123 Insufficient quality control is a present weakness of passive samplin

124 Quality control is critical for ensuring the safety and

125 Regular quality control is required in Poland only for those met

126 amino acid starvation a primary role of aaRS quality control is to help the cell mount an effective s

127 isomerase involved in ER protein folding and quality control, is secreted and interacts with the ECM.

128 tuting a major component of the cell protein quality control machinery essential to circumvent stress

129 protease is a component of the mitochondrial quality control machinery that regulates respiration, mi

130 nary arms races have shaped the cellular RNA quality control machinery.

131 rapy that is based on co-opting the cellular quality-control machinery-the ubiquitin-proteasome syste

132 drial dynamics are generally associated with quality control, maintaining the functionality of bioene

133 ty in taxonomic profiling for the Microbiome Quality Control (MBQC) project baseline study (MBQC-base

134 d sex and genotype-inferred sex is a crucial quality control measure in genome-wide association studi

135 ii) the development of quality assurance and quality control measures, (iii) the development of a rep

136 After implementing statistical quality control measures, the median CV on the original

137 mistakes during the fabrication process, and quality-control measures to ensure reproducible material

138 We recently described a non-canonical ER quality control mechanism for folding of thrombospondin

139 Thus, Kud acts as a quality control mechanism for LINC-mediated nucleocytosk

140 it has been suggested that this represents a quality control mechanism for subunit functionality.

141 for monitoring tRNA stability in a cellular quality control mechanism that degrades structurally dam

142 st time that the translation-like cycle is a quality control mechanism that ensures the fidelity of t

143 No-go decay (NGD) is a eukaryotic quality control mechanism that evolved to cope with tran

144 As a quality control mechanism, KPAF3 binding ensures that mR

145 arity of translocation reveals an unforeseen quality-control mechanism at the origin.

146 Autophagy is a quality-control mechanism that helps to maintain cellula

147 alled ribosome into subunits.Several protein quality control mechanisms are in place to trigger the r

148 Protein quality control mechanisms eliminate defective polypepti

149 mainly when interference with mitochondrial quality control mechanisms impedes their roles in mainte

150 Quality control mechanisms intervene appropriately when

151 several levels and by multiple mitochondrial quality control mechanisms present in the intermembrane

152 Endoplasmic reticulum (ER) quality control mechanisms target terminally misfolded p

153 The current report identifies quality control mechanisms that exclude the improper pol

154 The use of quality control mechanisms to stall developmental pathwa

155 However, whether RNA quality control mechanisms, such as nonsense-mediated mR

156 ata reveal a new mechanism for mitochondrial quality control mediated by Rab5 and early endosomes.

157 Current quality control method for botanical drugs is mainly bas

158 ed that the developed method was suitable as quality control method for rice bran in terms of identif

159 Quality control methods and considerations for optimizin

160 nomic profiling techniques, with established quality control methods, have been used to detect subtle

161 ssential RNA-seq primary analyses, including quality control metrics, transcript alignment, count gen

162 is pipeline and evaluated with comprehensive quality control metrics.

163 module, and an embedded but self-sufficient quality control module.

164 onprivate capture by the BAG6 subunit of the quality control module.

165 rmed using standardized methods with central quality control monitoring.

166 m of proteins representing the mitochondrial quality control (MQC).

167 ts emerge as more durable products and their quality control must include antioxidant capacity assays

168 promote mitophagy and maintain mitochondrial quality control necessary for optimal beta-cell function

169 The disruption of protein quality control networks is central to pathology in Hunt

170 rinsic insults, cells have evolved elaborate quality control networks to resolve damage at multiple l

171 cater to facilitate rigorous pre-processing, quality control, normalization and visualization of scRN

172 tioned to regulate transcription and perform quality control of both soluble and membrane proteins tr

173 of cardiomyocyte beat patterns is needed for quality control of cells intended for surgical injection

174 The fingerprints obtained are useful for quality control of cocoa beans allowing their differenti

175 ial is fit for the purpose of being used for quality control of ddPCR systems, consumables, instrumen

176 FQC is software that facilitates quality control of FASTQ files by carrying out a QC prot

177 omponent analysis (PCA) is a crucial step in quality control of genomic data and a common approach fo

178 dology proposed here may be used for routine quality control of infant formula and other food ingredi

179 We also show that quality control of integral membrane proteins by ribosom

180 Lysosomal proteolysis is essential for the quality control of intracellular components and the main

181 Here, we identify a new pathway for quality control of major facilitator superfamily transpo

182 ribonuclease PDE12 as a major factor for the quality control of mitochondrial non-coding RNAs.

183 owders), industrial manufacturing (e.g., for quality control of parts), or resource-limited settings

184 It could be easily applied for quality control of plant materials and their derived pro

185 ese findings provide novel insights into the quality control of plastid-localized proteins and establ

186 Collectively, Cdc37 performs a quality control of protein kinases, where induced confor

187 cled for cells to maintain energy and ensure quality control of proteins and organelles.

188 a key module of U5 snRNP while assuring the quality control of PRPF8.

189 Heuristic methods are often employed for quality control of putative homology clusters.

190 ent database updating, and the importance of quality control of RNA structures.

191 a well-balanced diet, and in the process and quality control of such products.

192 s as a membrane anchor, but the assembly and quality control of these proteins are poorly understood.

193 tial use in the food industry to perform the quality control of this dairy product.

194 The proposed method can be recommended for quality control of wine and disclosing adulterated sampl

195 ses at the fork, the clamp machinery directs quality control on the lagging strand and CMG enforces q

196 ntrol on the lagging strand and CMG enforces quality control on the leading strand.

197 d the possibility that they participate in a quality control pathway for folding of EGF repeats in pr

198 l membrane are cleared by a newly identified quality control pathway involving the conserved eukaryot

199 our results suggest that a cytosolic protein quality control pathway monitors folding and proteasome-

200 Recently, a quality control pathway was discovered in Bacillus subti

201 3 protein, due to induction of the autophagy quality control pathway.

202 ted protein product in this co-translational quality control pathway.

203 Mitophagy is a cellular quality-control pathway, which is essential for eliminat

204 biquitin-proteasome system are the two major quality control pathways responsible for cellular homeos

205 zed by aminoacyl-tRNA synthetases, which use quality control pathways to maintain substrate specifici

206 ns serve as a robust timer for translational quality control pathways to recognize stalled ribosomes.

207 k stop codons is one of the co-translational quality control pathways.

208 n-dependent cell signaling, degradation, and quality control pathways.

209 chored protein targeting and various protein quality-control pathways in the cytosol as well as regul

210 We develop a novel statistical quality control pipeline and accompanying R/Bioconductor

211 he Mammalian Phenotype Ontology, an improved quality control pipeline, and the addition of patient-fr

212 We used a standardized image-analysis and quality-control pipeline established by the ENIGMA conso

213 to both intranuclear and cytoplasmic protein quality control (PQC) aggregates under alkylation stress

214 cyte-homeostasis by concentrating on protein quality control (PQC) pathway and autophagy.

215 further used this method to identify protein quality control (PQC)-specific and compartment-specific

216 organellar remodeling, protein and organelle quality control, prevention of genotoxic stress, tumor s

217 t fraudulent instrumental work and implement quality control, principal component analysis (PCA) and

218 es of RNA-seq will aid in improvement of the quality control procedure and development of statistical

219 mentation of this approach in industry-based quality control procedures would contribute to the stand

220 udes considerations for NGS test validation, quality control procedures, proficiency testing, and ref

221 t NMD-mediated RNA surveillance is a crucial quality control process that contributes to longevity co

222 odel provides insight into the regulation of quality control processes and the manner by which they r

223 ming recognized as a key hub for integrating quality control processes associated with protein biosyn

224 is sensed by the cell to initiate downstream quality control processes.

225 that catalyzes RNA turnover, maturation, and quality control processes.

226 cations for CT, training of technicians, and quality control programs will reduce the necessary radia

227 rate-bound inner mitochondrial membrane AAA+ quality control protease in yeast, YME1.

228 out its life cycle by multiple mitochondrial quality control proteases.

229 Purification and quality-control protocols for the oligosaccharide produc

230 on of CCR2 needs to be closely monitored for quality control purpose when MDSC are generated in vitro

231 ompatibility with the cupping evaluation for quality control purposes.

232 ccessibility respectively, and comprehensive quality control (QC) and analysis tools are critical to

233 me and effort to be spent on pre-processing, quality control (QC) and normalization.

234 set of pooled human sera exposed to OPNAs as quality control (QC) materials, the developed method suc

235 Quality control (QC) metrics are critical in high throug

236 -purpose software toolkit for reference-free quality control (QC) of WGS reads and de novo genome ass

237 ave different approval pathways but the same quality control (QC) paradigm, where the quality of rele

238 nslation are resolved by ribosome-associated quality control (QC) pathways that oversee mRNA and nasc

239 All of these data need to pass some form of quality control (QC) processing and checking before they

240 Disk diffusion and MIC quality control (QC) ranges were determined for nafithro

241 In spiked quality control (QC) samples 82% of metabolite measureme

242 An important quality control (QC) step in these studies is to ensure

243 A quality control (QC) study was performed to establish di

244 aving a unique dilution pattern, alongside a quality control (QC) that serves as a reference in every

245 ass spectrometry (LC-MS)-based metabolomics, quality control (QC), molecular identification using MS/

246 coopted from its role as a critical protein quality-control regulator to having a central role in sy

247 ChiLin generates comprehensive quality control reports that include comparisons with hi

248 In eukaryotes, the ribosome-bound quality control (RQC) complex detects aberrant nascent p

249 d stalling initiated the ribosome-associated quality control (RQC) pathway for degradation of nascent

250 product is degraded by the ribosome-mediated quality control (RQC) system.

251 sequences (CDS) triggers ribosome-associated quality control (RQC), followed by degradation of the ab

252 When quality control samples are systematically included in b

253 ed 126 identical human plasma samples and 29 quality control samples from a nutritional intervention

254 metabolite batch and run-order effects using quality control samples.

255 imum acceptable intralaboratory variation on quality control samples.

256 Loss of protein and organelle quality control secondary to reduced autophagy is a hall

257 n drug discovery and development but also in quality control settings.

258 cellular proteins and is involved in protein quality control, signalling and cell death.

259 s a key player in the regulation of ribosome quality control specifically on mitochondria-localized r

260 Batch release quality control specifications were established to meet

261 as a precision control mechanism in protein quality control, stability, localization, and maturation

262 efore this technology can be used in lieu of quality-controlled standard assays.

263 Our RNA-Seq libraries met high quality control standards and accurately captured differ

264 Bypassing this quality control step produces defects in reading frame m

265 sis in pre-Aire MHCII(lo) mTECs points to a "quality control" step during early mTEC differentiation.

266 The quality control steps and self-fitting methods make Repl

267 applications of this technique might be for quality control, study of fractionation processes and de

268 nor degradation by the mitochondrial protein quality control system were observed.

269 d degradation (ERAD) is an important protein quality control system which maintains protein homeostas

270 g various components of the cellular protein quality control system.

271 t of a thin-layer chromatography (TLC)-based quality control system.

272 ide important insights into the mRNA/protein quality-control system in humans, which could be a poten

273 Therefore modulation of the ER quality control systems may be a potential therapeutic r

274 Three mRNA quality control systems monitor mRNAs for translational

275 Quality control tests were performed for both scanners.

276 rs describe a mechanism of ribosome-mediated quality control that involves the ubiquitination of ribo

277 n other species defective for aminoacylation quality control, the growth rate of the ileS(T233P) stra

278 After quality control, the primary analysis included 29,838 pa

279 After quality control, the study analyzed data from 69 childre

280 After quality control, thirteen subjects were included in the

281 ough diverse examples, ranging from NGS data quality control to characterization of enhancer regions

282 tion elongation and impacts co-translational quality control to minimize production of aberrant prote

283 he animals is particularly important for RNA quality control to promote longevity.

284 ed monitoring of Gram stains is an essential quality control tool for laboratories and is necessary f

285 Induced Breakdown Spectroscopy (LIBS) to the quality control, traceability and detection of adulterat

286 y demonstrates the feasibility of conducting quality-controlled trials for this disease stage in the

287 hese independent datasets were processed and quality-controlled using the same methods, but analyzed

288 For radio-TLC quality control, various mobile phases were analyzed usi

289 ading pathways, requirements for translation quality control vary depending on cellular physiology an

290 l dynamics, reduced organelle biogenesis and quality control via mitophagy, accumulation of mitochond

291 When TLC quality control was performed on silica gel 60 plates, 4

292 Following data quality control, we analysed 22 single nucleotide polymo

293 s of K11/K48-linked chains in cell-cycle and quality control, we establish heterotypic ubiquitin conj

294 Through data integration and quality control, we provide a scored human protein-prote

295 hip between chronic inflammation and protein quality control, we used a mouse model of dilated cardio

296 , had an acceptable record according to CPRD quality control, were approved for CPRD and Hospital Epi

297 (CRLB%) values, which are typically used for quality control, were not reflective of the increased qu

298 h of neuronal proteostasis and mitochondrial quality control, which, when dysfunctional or diminished

299 tion studies and clinical trials, as well as quality control within and across laboratories.

300 Hsp70 chaperone activity and improve protein quality control without need for Hsp70 induction.