ライフサイエンスコーパス: quantitation

1 niformity, count rate performance, and image quantitation.

2 rejection of interferences and multi-analyte quantitation.

3 spectra to calculate abundances for accurate quantitation.

4 intact glycopeptides for identification and quantitation.

5 can result in up to an 8-fold difference in quantitation.

6 yer is analyzed using the ImageJ program for quantitation.

7 et abundance, enabling relative and absolute quantitation.

8 non-assay related factors can affect gluten quantitation.

9 tion coupled with automated, high-throughput quantitation.

10 lank, 2% limit of detection, and 5% limit of quantitation.

11 terfere with metabolite signal detection and quantitation.

12 t from metabolites of interest, was used for quantitation.

13 nfocal microscopy, and intracellular calcium quantitation.

14 negatively affects PET/CT image quality and quantitation.

15 guish different repeats or allow comparative quantitation.

16 viously shown to be applicable for MALDI-MSI quantitation.

17 uired and for more common cases of NMR-based quantitation.

18 therefore add to the overall uncertainty in quantitation.

19 offers a substantial improvement in protein quantitation.

20 main employing LC-MS/MS analysis for product quantitation.

21 stable isotope dilution (SID) for metabolite quantitation.

22 We consider the optimum height for quantitation.

23 y) is FDA cleared for blood plasma HIV-1 RNA quantitation.

24 ive recombinant antibody for specific adduct quantitation.

25 istent quantitation than using intraspectrum quantitation.

26 dent and data-independent modes for relative quantitation.

27 for the ultimate purpose of total bilirubin quantitation.

28 t levels and at the lower and upper limit of quantitation (0.20 and 0.67, respectively) were less tha

29 sed biosensor capable of ultra-low (limit of quantitation: 0.1 pM) detection.

30 titer at least as high as the lower limit of quantitation (1:8 or 1:16) for all 4 strains combined af

31 analysis such as abused drugs restricts the quantitation ability of LFA strips.

32 own its great potential to improve limits of quantitation, accelerate analysis throughput, and dimini

33 as the two representative test samples, the quantitation accuracy was measured to be 80% to 120% for

34 etabolite information for identification and quantitation, ADAP-GC 2.0 requires appropriate specifica

35 The quantitation agreed within 2% of the known activity dist

36 p-Q performs proteoform alignment to support quantitation analysis across replicates/samples.

37 s, not requiring high-resolving power MS for quantitation and being relatively inexpensive.

38 mance of downstream analyses like transcript quantitation and differential testing.

39 In summary, this approach yields accurate quantitation and discovery of protein PTMs in complex bi

40 mass spectrometry is now widely used for the quantitation and identification of organic compounds in

41 ET/MRI of the aortic valve could improve PET quantitation and image quality.

42 ance (MR) probe that enables the ratiometric quantitation and imaging of pH through chemical exchange

43 e of confocal Raman microscopy as a tool for quantitation and molecular-scale structural characteriza

44 omes into recipient circulation and that the quantitation and profiling of donor intra-exosomal cargo

45 AC-see with flow cytometry enables automated quantitation and prospective cell isolation as a functio

46 We present RASQUAL (Robust Allele-Specific Quantitation and Quality Control), a new statistical app

47 abor-saving, easy automation, and convenient quantitation) and also the high sensitivity of silver st

48 od sensitivity, limit of detection, limit of quantitation, and selectivity.

49 We tested these quantitation approaches by spiking standard proteins int

50 )O provides superior DNA labeling enrichment quantitation, as measured by GC-positive chemical ioniza

51 onfidence in the use of a single IA-LC-MS/MS quantitation assay.

52 n of stable, nanoparticle-based activity and quantitation assays in resource-limited areas where conv

53 (SVR12; HCV RNA less than the lower limit of quantitation at 12 weeks after the end of all study ther

54 t viral kinetics (HCV RNA below the level of quantitation at week 1, P = 0.003).

55 utomatically performs large-scale proteoform quantitation based on interspectrum abundance in top-dow

56 Isobaric tags for relative and absolute quantitation-based relative quantitation mass spectromet

57 tion/desorption times (5 min/5 s), limits of quantitation below the minimum required performance leve

58 anned doping substances, achieving limits of quantitation below the minimum required performance limi

59 orward but has not been applied as widely as quantitation by chromatographic peak areas or peak inten

60 Quantitation by flame atomic absorption spectrometry yie

61 Large molecule quantitation by LC-MS/MS commonly relies on bottom-up or

62 and nicarbazin in egg were optimized for its quantitation by liquid chromatography.

63 n in anti-adipogenic differentiation through quantitation by oil-red O staining.

64 WBQ ultimately performs quantitation by projecting hmax from the width, provided

65 dresses the harmonization challenge in lipid quantitation by providing a semiautomated process, indep

66 oftware, called bioluminescent-based analyte quantitation by smartphone (BAQS), provides an opportuni

67 ex protein background and comparing relative quantitation by spectral counts with normalized chromato

68 trophoretic migration and enable multiplexed quantitation by tandem MS.

69 ocessing, and enzymatic hydrolysis on gluten quantitation by various ELISA kits was evaluated.

70 Thus, digital RNA quantitation constitutes a sensitive and specific CTC re

71 The available immunomethods for gluten quantitation could underestimate or overestimate the net

72 With quantitation demonstrated at 1% (w/w), or 50 ng, OSCS in

73 he ELISA kits exhibited variations in gluten quantitation depending on the gluten-containing grain an

74 The source of gluten can influence gluten quantitation due to variability in protein profile of gr

75 set, there is a single height- or area-based quantitation equation.

76 ontrol, were not reflective of the increased quantitation error arising from acceleration.

77 From these results, the limits of quantitation for cobalt, nickel, and lead ions were repo

78 With on-chip desalting, the limit of quantitation for histidine spiked in aCSF is approximate

79 charge state of the analyte were used during quantitation for optimized sensitivity.

80 ith stable isotope labeling in cells (SILAC) quantitation for PAF-C phosphorylation from wild-type an

81 m the metabolic co-factors NADH and FAD with quantitation from Fluorescence Lifetime Imaging Microsco

82 It also has a quantitation function that automatically generates calib

83 Absolute pixel-to-pixel quantitation has remained a challenge, primarily lacking

84 etion detection sensitivity through absolute quantitation, improved precision and reduced assay stand

85 acy of dual-energy computed tomographic (CT) quantitation in a phantom system comparing fast kilovolt

86 bel-free approach for inorganic nanoparticle quantitation in cells.

87 uitable alternative for fumonisins B1 and B2 quantitation in corn-based feeds.

88 Here, we report on accurate miRNA quantitation in crude cell lysate by a CE-based hybridiz

89 easibility of attaining femtomolar limits of quantitation in electroanalysis.

90 d proved to be more accurate than label-free quantitation in our hands.

91 HIV-1 RNA quantitation in plasma, or virus load testing, is the pr

92 Limits of quantitation in the subnanogram per milliliter range can

93 We show that the limit of quantitation is 1.9x10(5) CFU/mL with this simple device

94 An automated tool for interspectrum quantitation is a pressing need.

95 Hence, quantitation is an important aspect of a comprehensive g

96 Quantitation is based on the UV-vis spectra.

97 ontaining peptides; additionally, label-free quantitation is used to ascertain catalytic efficiency v

98 ally labeled reference peptides for absolute quantitation, it also supports the analysis of labeled a

99 of utilizing single spectrum for proteoform quantitation, iTop-Q constructs extracted ion chromatogr

100 sing isobaric tags for relative and absolute quantitation (iTRAQ) 4-plex, >4,500 proteins are detecte

101 the isobaric tags for relative and absolute quantitation (iTRAQ) based comparative proteomics.

102 use isobaric tags for relative and absolute quantitation (iTRAQ) labeling technology to explore impo

103 sing isobaric tags for relative and absolute quantitation (iTRAQ) quantitative proteomics approach.

104 ying isobaric tags for relative and absolute quantitation (iTRAQ)-labels.

105 17beta-estradiol was detected below its quantitation limit in a sample taken downstream from a w

106 A1c levels (0.1%-8.36%) with a detection and quantitation limit of 0.024% (3sigma/slope) and 0.08% (1

107 ed from enzymatic digestion, but had a lower quantitation limit to meet the sensitivity requirement t

108 or accuracy, repeatability and detection and quantitation limits indicating its adequacy.

109 The detection and quantitation limits were 2.1 and 6.8microgL(-1), respect

110 very was >/=87.9% at both the lower limit of quantitation (LLOQ) and the upper limit of quantitation

111 he limit of detection (LOD) and the limit of quantitation (LOQ) being, respectively, 0.29ng/mL and 1.

112 Limit of detection (LOD) and limit of quantitation (LOQ) in samples were 0.03-0.06 and 0.12-0.

113 shed 24 PE and 6 PC lipids over the limit of quantitation (LoQ) that prior to modification were above

114 all the studied compounds, and the limits of quantitation (LOQs) were within the range of 0.1 to 10 n

115 rologic response (HCV RNA below the limit of quantitation [<15 IU/mL]) 12 weeks after treatment compl

116 intraspectrum charge state deconvolution and quantitation, manual processing is still required to qua

117 ive and absolute quantitation-based relative quantitation mass spectrometry proteomics were performed

118 re, the tests yielded satisfactory limits of quantitation (median, approximately 0.5 ng mL(-1)), line

119 ledge, this is the most sensitive DNA adduct quantitation method yet reported, exceeding the sensitiv

120 lts with those obtained by a benchmark miRNA-quantitation method-quantitative reverse transcription-p

121 ve been developed for miRNA isolation, miRNA quantitation, miRNA profiling, miRNA target detection, a

122 argeted mass spectrometry assays for protein quantitation monitor peptide surrogates, which are easil

123 et show that iTop-Q achieves highly accurate quantitation, more consistent quantitation than using in

124 UVR at 60-90 min after injection gave robust quantitation of (18)F-GE180, which correlated well with

125 concentration with an average lower limit of quantitation of 0.01 mg/mL for both of them.

126 -CBS technology was used for the concomitant quantitation of 18 compounds (mixture of anabolics, beta

127 generated to establish an accurate receptor quantitation of a panel of lung and gastric cancer cell

128 ensitive diagnostic assay for the ultratrace quantitation of a phosphoryl fluoride nerve agent surrog

129 precise diagnostic assay for the ultratrace quantitation of a thiophosphate nerve agent surrogate.

130 ion of illicit drugs in human blood, and the quantitation of accelerants in arson investigations, to

131 hieve simultaneous direct identification and quantitation of acetaldehyde, pyruvic acid, acetoin, met

132 analytical platforms enabling detection and quantitation of adulteration.

133 ue is the first MS-based method for absolute quantitation of AKT peptides from cancer tissues.

134 s efficiently in cells, allowing imaging and quantitation of ALKBH3 activity by microscopy and flow c

135 PS species as well as the identification and quantitation of an additional 4 PE and 4 PS species that

136 Detection and quantitation of antibiotic residues in blood serum and a

137 f utilizing aminoxyTMT reagents for reliable quantitation of biological glycomic samples.

138 idated here for the first time for in planta quantitation of biopharmaceuticals, is especially useful

139 olymerase chain reaction of genomic DNA, and quantitation of Bmp6 messenger RNA expression from isola

140 The accuracy of the resulting in vivo quantitation of calcification, lipid-rich necrotic core

141 alization was assessed at 12 weeks of age by quantitation of calcium deposits in the muzzle skin cont

142 ectrophotometry was successfully applied for quantitation of carotenoids in fruit juices.

143 Quantitation of cellular LAMP2 and NPC1 protein levels s

144 Spatial resolved quantitation of chemical species in thin tissue sections

145 Our SRP microscope enables fast quantitation of chemicals in a 3D volume through a two-d

146 Analytical methods for detection and quantitation of chloramphenicol in blood serum and foods

147 enoviral transduction and 24-h culture, with quantitation of cholesterol composition and intracellula

148 IgE class switch was analyzed by quantitation of class switch transcripts.

149 fused and chemometrically processed for the quantitation of coeluting analytes.

150 For quantitation of concentrations in the parts per billionv

151 FST permitted quantitation of cone and rod sensitivity in these patien

152 ve, while overall time for the detection and quantitation of Cyt c from isolated mitochondria is only

153 ing three different sets of PCR reagents for quantitation of cytomegalovirus (CMV).

154 instrumental artifacts are critical for the quantitation of data obtained with fluorescent protein (

155 r of biomolecules with drugs, as well as for quantitation of diagnostic markers in biofluids.

156 through cytokine profiling, microscopy, and quantitation of epithelial recovery from exfoliation.

157 ported outcomes (PROs) and computer-assisted quantitation of extent of fibrosis (QLF) and of total IL

158 istones in organ viability and suggests that quantitation of extracellular histones might contribute

159 The limits of detection and quantitation of FA were 1.4ng/mL and 3.1ng/mL, respectiv

160 eaction monitoring (SRM) allows simultaneous quantitation of five molecular species derived from tras

161 v greatly facilitates the identification and quantitation of flavonoids from UHPLC-HRAM-MS(n) data.

162 In this study, the quantitation of free amino acids and Amadori products (A

163 (FMOC-Cl) was determined to be effective for quantitation of fumonisins B1 and B2 in feed.

164 retinoid were evidenced by HPLC analysis and quantitation of fundus autofluorescence; this effect is

165 Quantitation of gluten proteins showed that defatting wi

166 te broad applications of identifications and quantitation of glycoproteins.

167 ivity of CoOxH-GO is utilized herein for the quantitation of H2O2 in a wide concentration range, from

168 etermined, yet to date, the exact nature and quantitation of HBeAg still remain uncertain.

169 assays or validated in-house assays for the quantitation of HIV RNA in CSF and seminal plasma.

170 study, the Aptima assay was applied for the quantitation of HIV RNA in peripheral blood mononuclear

171 Mass spectroscopic quantitation of human antibody binding demonstrated that

172 Quantitation of ICAM-1 protein expression on cells and v

173 Quantitation of images was performed by normalizing to e

174 ensional (3D) tissue cytometry: an automated quantitation of immune cells and associated spatial para

175 lly, we show the use of VTEA for large-scale quantitation of immune cells in entire human kidney biop

176 ght and heavy peaks allowed for the relative quantitation of intact proteins in three popular model o

177 formate adduct was developed, and it allowed quantitation of lactose and lactulose in all samples at

178 analytical tool for both identification and quantitation of lipid C=C location isomers from complex

179 It allowed quantitation of low ppb levels of tryptophan and its der

180 vides an opportunity for onsite analysis and quantitation of luminescent signals from biological and

181 rface Plasmon Resonance (SPR) sensor for the quantitation of lysozyme dimer in monomer-dimer mixtures

182 d bioanalytical method that permits absolute quantitation of metabolites in biological samples withou

183 bromide (PAB) for the targeted detection and quantitation of methionine-containing peptides in SPROX

184 ed proteomics strategy for the detection and quantitation of methionine-containing peptides in SPROX

185 lications of SPROX is the identification and quantitation of methionine-containing peptides.

186 Accurate quantitation of microRNA (miRNA) in tissue samples is re

187 By improving the imaging and quantitation of microtubule alignment within developing

188 purpose procedure for the identification and quantitation of moniliformin in cereals becomes availabl

189 ch enables the profiling, identification and quantitation of monoglyceride regioisomers directly from

190 allowing for the identification and absolute quantitation of multiple core transcription factors and

191 detection for fast, accurate, and sensitive quantitation of multiple miRNAs.

192 a multiplexed QXL-MS strategy, namely, QMIX (Quantitation of Multiplexed, Isobaric-labeled cross (X)-

193 eport for the first time on the simultaneous quantitation of nicotinamide riboside, nicotinamide mono

194 A new optosensor for visual quantitation of nitrite (NO2(-)) ion has been fabricated

195 A-based methods, this assay enables separate quantitation of non-phosphorylated full-length guide str

196 f minimal residual disease, as determined by quantitation of NPM1-mutated transcripts, provided power

197 ibed method can readily be applicable to the quantitation of other biotherapeutic proteins in the ADA

198 The assay-principle should be extendable to quantitation of other nucleophilic or electrophilic and

199 t, although with significant matrix effects, quantitation of penicillin G, a common antimicrobial, is

200 tandem mass spectrometry sequencing and AACT quantitation of peptides provided unambiguous identifica

201 esents a systematic approach to the accurate quantitation of plasma SEPP1 at clinical levels using SS

202 degrees C), and membrane localization on the quantitation of preformed dimers using SW-FCCS, DC-FCCS,

203 fication strategy for the identification and quantitation of primary functional human MEPs from granu

204 VC/ESI-MS/MS) system for online and absolute quantitation of propranolol in mouse brain, kidney, and

205 Quantitation of protein concentrations by reversed-phase

206 mapping is well suited to the discovery and quantitation of protein heterogeneity; however, the inte

207 c/average molecular weight determination and quantitation of proteoforms from LC-MS(1) spectra.

208 Quantitation of raphe was affected by the resolution of

209 is highly expressed on plasma cells, permits quantitation of rare circulating plasma cells (CPCs) in

210 The method for simultaneous quantitation of seven chemical markers in guarana proved

211 A method for the simultaneous quantitation of seven markers in guarana by HPLC-PDA was

212 for low limit-of-detection and reproducible quantitation of signaling pathway members using a bencht

213 liver fibrosis, as evidenced by morphometric quantitation of Sirius Red staining and increased mRNA l

214 r (13)C-MFA frequently hinder assignment and quantitation of site-specific (13)C enrichment.

215 l through several applications including the quantitation of small molecules such as drugs and neurot

216 olatile fractions of benzoin balsams and the quantitation of some of the major components by gas and

217 oyed single molecule FRET to obtain a direct quantitation of stably formed-, weakly folded and unfold

218 aphy allows noninvasive and patient-specific quantitation of strain intensities because of MV deforma

219 et-red color and can be easily used both for quantitation of sulfonamides using spectrophotometry and

220 otope-labeled standards facilitates accurate quantitation of targeted metabolites in large-scale meta

221 Analytical techniques for detection and quantitation of tetracyclines in food products are great

222 metric method for the detection and relative quantitation of the adulteration of meat with that of an

223 ction-based ELISA principle (ReactELISA) for quantitation of the carbon nucleophilic lipid metabolite

224 l the compounds in only 12 min and selective quantitation of the compounds was achieved.

225 liquid chromatography-MS method that enabled quantitation of the different variants.

226 ination of its periplasmic concentrations by quantitation of the first hydrolysis product, phenylalan

227 Quantitation of the HIV-1 viral load in plasma is the cu

228 Strikingly, quantitation of the ion atmosphere content indicates tha

229 Quantitation of the kinetics of depletion of biotinylate

230 The relative quantitation of the major peanut allergens showed little

231 Our methodology permits an explicit quantitation of the mediation of phenotypic associations

232 luidic device could be a useful tool for the quantitation of the migratory capability and anti-metast

233 RNA2DNAlign is based on quantitation of the relative abundance of variant and re

234 The distinction and quantitation of the unsaturated lipid isomers, however,

235 l fluorescence and two-photon approaches and quantitation of their concentration in biological tissue

236 Sufficient separation and reliable quantitation of these bsAb homodimers using liquid chrom

237 a successful separation, identification, and quantitation of these complex self-assemblies with regar

238 pendent DBS-SPE-LC-MS/MS bioanalysis for the quantitation of these representative controlled substanc

239 Laminin immunostaining and quantitation of tissue extractions revealed increased Lm

240 For parts per quadrillionvolume (ppqv) vapor quantitation of TNT and RDX, an online PTV-GC system wit

241 lication of one of the sulfides for relative quantitation of total thiols in live cells through fluor

242 Quantitation of trace-level (mug/L to ng/L) volatile com

243 nd transferrable procedure permits surrogate quantitation of transcription factor activity over the l

244 ediction of translated small ORFs (sORFs) by quantitation of translation termination and peptidic ana

245 n and SUMO-modified proteomes using parallel quantitation of ubiquitylated and SUMOylated peptides.

246 It enabled quantitation of unsaturated FAs from various biological

247 Quantitation of unsaturated FAs with confident carbon-ca

248 cialized isobaric tags which enable relative quantitation of up to six different glycan samples simul

249 mainstay of clinical virology, and accurate quantitation of viral load among labs requires the use o

250 om mRNA to protein, but does not specify the quantitation or timing of this process across the genome

251 On quantitation, patients showed a 30% mean decrease in tot

252 This quantitation platform can also distinguish single base m

253 dization chain reaction was employed in this quantitation platform for highly sensitive assays that c

254 he new strategy lays the foundation for this quantitation platform to be applied in forensic analysis

255 Here, we introduce protein-lipidation quantitation (PLQ)-the first method for quantitative ana

256 was needed and the method, based on LC-MS/MS quantitation, proved matrix-independent.

257 dies as reagents for capture, detection, and quantitation purposes is most commonly used to monitor H

258 hesized as an internal standard for accurate quantitation purposes.

259 S) to quantitate 28 polar OAs with limits of quantitation ranging from 0.25 to 50 muM.

260 Height- and area-based quantitation reduce two-dimensional data to a single val

261 of which the hematocrit effect on DBS-based quantitation remains undoubtedly the most widely discuss

262 effects of NUS and CS reconstruction on the quantitation results are unknown.

263 with this device reveal similar nanoparticle quantitation results to those acquired with a much large

264 cantly higher than the instrumental limit of quantitation (S/N 10).

265 uorescence microscopy images, along with DNA quantitation, showed that both PCL+FA and PCL scaffolds

266 Quantitation stability of a (68)Ge flood phantom was dem

267 issues affecting sensitivity and accuracy of quantitation still exist, and the development of more ef

268 Although numerous MS-based quantitation strategies have been developed in the past

269 exist, and the development of more effective quantitation strategies is still required.

270 and comparison of these label-free top-down quantitation strategies using spiked proteins, spectral

271 ral counting is a straightforward label-free quantitation strategy used in bottom-up proteomics workf

272 Many DNA quantitation systems can be accurately calibrated with s

273 ificance of differential abundance from each quantitation technique are evaluated against the expecte

274 ighly accurate quantitation, more consistent quantitation than using intraspectrum quantitation.

275 ere AssayR provides more accurate and robust quantitation than XCMS, and we propose that tailored pea

276 aper, we describe a novel method for analyte quantitation that does not rely on calibrants, internal

277 the matrix onto tissue sections resulted in quantitation that was not statistically significantly di

278 lled iTop-Q (intelligent Top-down Proteomics Quantitation), that automatically performs large-scale p

279 or emission maxima that would enable precise quantitation through ratiometric imaging.

280 tion of targeted information, enables better quantitation thus providing an advanced analytical tool

281 ed in Belgium ranged from below the limit of quantitation to 1072 ng L(-1), with 2-ethylhexyl phenyl

282 This allowed absolute quantitation to be achieved with an external calibration

283 Nasopharyngeal samples for viral load quantitation, typing, and genotyping, and blood samples

284 f quantitation (LLOQ) and the upper limit of quantitation (ULOQ) along with acceptable selectivity an

285 ata processing, followed by verification and quantitation using parallel reaction monitoring (PRM).

286 ides (or housekeeping protein peptides), but quantitation using western blots showed 6.3- to 8-fold o

287 The limit of quantitation was 10mug/kg for benzylpenicillin, 20mug/kg

288 Quantitation was based on proteins for which heat-stable

289 wavelength 277nm and 289nm respectively and quantitation was carried out by first order derivative m

290 PET stability metrics demonstrated that PET quantitation was not affected during simultaneous aggres

291 We propose a width-based quantitation (WBQ) paradigm complementing height or area

292 The preceding paper introduced width-based quantitation (WBQ).

293 Corroborating these with multiplex RNA quantitation, we found that multiple IFN-inducible genes

294 Accuracy and precision of miRNA quantitation were determined for miRNA samples in a crud

295 calculated limits of detection and limits of quantitation were found to be in the ranges 0.05-0.13mug

296 he presence of inhibitors, and more accurate quantitation when amplification efficiency is low, make

297 are required to support accurate metabolite quantitation which in turn enables efficient analysis of

298 -exchange chromatography (IEC) detection and quantitation, which is slow, laboursome and costly.

299 enabled glycan characterization and relative quantitation with minimal side reactions: the MALDI-TOF-

300 In addition, quantitation with minimally processed rat plasma samples