ライフサイエンスコーパス: quantitative trait

1 able (dichotomised by median onset) and as a quantitative trait.

2 ons between genetic markers and neuroimaging quantitative traits.

3 tween gene-regulatory changes and control of quantitative traits.

4 o estimate the effect of genetic variants on quantitative traits.

5 e and effective method for exploring complex quantitative traits.

6 The method accommodates both binary and quantitative traits.

7 n of novel loci contributing to diseases and quantitative traits.

8 els (LMMs), which are primarily designed for quantitative traits.

9 ributing to naturally occurring variation in quantitative traits.

10 ations in faba bean seeds may be independent quantitative traits.

11 the ability to dissect the genetic basis of quantitative traits.

12 o a wide range of complex human diseases and quantitative traits.

13 ntribute to naturally occurring variation in quantitative traits.

14 Expression quantitative trait analyses suggest plausible candidate

15 Expression quantitative trait analysis provides tentative evidence

16 We applied the method to existing quantitative trait and binary outcome meta-analyses (hum

17 nity will enhance our understanding of maize quantitative traits and boost crop molecular breeding de

18 SCOPA can be applied to quantitative traits and categorical phenotypes, and can

19 alyse the effects of SVs on gene expression, quantitative traits and intrinsic reproductive isolation

20 ese structural variant traits are treated as quantitative traits and mapped genetically, analogously

21 opmental disorders, the relationship between quantitative traits and physiological markers has become

22 allow variance in individual trajectories of quantitative traits and their population-level outcomes

23 association between metabolites (treated as quantitative traits) and genetic variants (e.g., SNPs) h

24 yzed large-scale GWAS summary data across 36 quantitative traits, and identified 25 genomic regions t

25 ely, despite the fact that many diseases and quantitative traits are correlated with each other, and

26 Many quantitative traits are labile (e.g. somatic growth rate

27 Quantitative traits are often influenced by many loci wi

28 c factors responsible for the variations (or quantitative traits) are largely unknown.

29 of T2D-associated loci based on T2D-related quantitative trait associations revealed tissue-specific

30 rred strong stabilizing natural selection on quantitative traits because genetic variation among wild

31 y relevant GO categories associated with the quantitative trait, chill coma recovery time, in the unr

32 acrostructure, delineate regions involved in quantitative traits, complement functional genomic inves

33 In natural populations, quantitative trait dynamics often do not appear to follo

34 c basis of the type 2 diabetes (T2D)-related quantitative traits fasting glucose (FG) and insulin (FI

35 lity of linkage map for QTL mapping of three quantitative traits, flag leaf length, width, and area,

36 ase chain reaction, we identified Slit2 as a quantitative trait gene whose expression was positively

37 Quantitative trait genes have been difficult to analyze

38 enotypes and functional testing of candidate quantitative traits genes (QTGs).

39 ertainty of the genetic model for non-normal quantitative trait genetic association study.

40 ms, enriched for causal variants affecting a quantitative trait in a population with low degree of re

41 sequence association analyses of hematologic quantitative traits in 15,459 community-dwelling individ

42 oci and studying the genetic architecture of quantitative traits in admixed populations.

43 Quantitative traits in plants are controlled by a large

44 e elucidation of the genetic architecture of quantitative traits in plants.

45 s for evolution and for our understanding of quantitative traits including complex human diseases.

46 rce will facilitate genetic investigation of quantitative traits, including brain and behavioral phen

47 nge, the complicated genetic architecture of quantitative traits is beginning to be understood.

48 , achieving such a detailed understanding of quantitative traits is important, as it can improve our

49 and found evidence of cis-acting expression quantitative trait loci (cis-eQTL) for 869 expressed gen

50 Mapping cis-acting expression quantitative trait loci (cis-eQTL) has become a popular

51 slet samples to produce dense cis-expression quantitative trait loci (cis-eQTL) maps.

52 o associated with one or more cis-expression quantitative trait loci (cis-eQTLs) and/or splicing eQTL

53 trained to recognize SNVs in cis-expression quantitative trait loci (cis-eQTLs) using a set of 92 ge

54 ites, which we named canalization metabolite quantitative trait loci (cmQTL).

55 a proof of principle, we mapped connectivity quantitative trait loci (cQTLs) using parallel genotype

56 e trait loci (eQTLs) and DNase I sensitivity quantitative trait loci (dsQTLs) in a tissue-specific ma

57 and validated these results using expression quantitative trait loci (eQTL) analysis and clinical phe

58 Expression quantitative trait loci (eQTL) analysis is a method to i

59 Using expression quantitative trait loci (eQTL) analysis, we found that t

60 pe data, we identified 47,587 cis-expression quantitative trait loci (eQTL) and 6,695 trans-eQTL asso

61 al non-coding variants, including expression quantitative trait loci (eQTL) and disease-associated mu

62 nscription factor binding to both expression quantitative trait loci (eQTL) and genome-wide associati

63 n gene expression levels using an expression quantitative trait loci (eQTL) approach.

64 4 cis and 3,791 trans independent expression quantitative trait loci (eQTL) by using linear mixed mod

65 Regulatory feature analysis and expression quantitative trait loci (eQTL) data showed that this loc

66 pplied it to three GWASs and four expression quantitative trait loci (eQTL) datasets.

67 pe and sequence data, such as for expression quantitative trait loci (eQTL) detection, require perfec

68 me-wide mapping identified 25 660 expression quantitative trait loci (eQTL) for 17 311 genes, capturi

69 The studies of expression quantitative trait loci (eQTL) have shown that regulator

70 Studies of expression quantitative trait loci (eQTL) indicate that genetic var

71 Expression quantitative trait loci (eQTL) mapping is a widely used

72 We identified a depletion of expression quantitative trait loci (eQTL) on the X Chromosome, espe

73 ied functional annotation such as expression quantitative trait loci (eQTL) or Hi-C genome conformati

74 tion studies (GWAS) identify 5311 expression quantitative trait loci (eQTL) regulating the expression

75 Genome-wide expression Quantitative Trait Loci (eQTL) studies in humans have pr

76 genomics, exemplified by numerous expression Quantitative Trait Loci (eQTL) studies.

77 s well as in a multi-tissue mouse expression quantitative trait loci (eQTL) study where our method in

78 portant to map the aforementioned expression quantitative trait loci (eQTL) using a statistically dis

79 ave facilitated identification of expression quantitative trait loci (eQTL), the genetic determinants

80 Mapping expression quantitative trait loci (eQTL), we identify 417 response

81 onstrate that lncRNAs overlapping expression quantitative trait loci (eQTL)-associated single nucleot

82 loited while mapping multi-tissue expression quantitative trait loci (eQTL).

83 s SNPs (in NDUFA11 and KIAA1755), expression quantitative trait loci (eQTLs) (influencing GNG11, RGS6

84 Expression quantitative trait loci (eQTLs) across all annotated tra

85 We identified 21,183 expression quantitative trait loci (eQTLs) and 6,768 splicing quant

86 (HLCs) for genome-wide mapping of expression quantitative trait loci (eQTLs) and allele-specific expr

87 is-regulatory variation including expression quantitative trait loci (eQTLs) and DNase I sensitivity

88 Conditioned on a tissue, expression quantitative trait loci (eQTLs) are genetic variants ass

89 Expression quantitative trait loci (eQTLs) are genetic variants tha

90 ion, some of which corresponds to expression quantitative trait loci (eQTLs) at these loci.

91 MDP, reveals both local and trans expression Quantitative Trait Loci (eQTLs) demonstrating 2 trans eQ

92 ts in 57 GWASs with 24 studies of expression quantitative trait loci (eQTLs) from a broad range of ti

93 About ~65% of expression quantitative trait loci (eQTLs) have primary effects on

94 Expression quantitative trait loci (eQTLs) help to explain the regu

95 The majority of known expression quantitative trait loci (eQTLs) impact expression of loc

96 We mapped cis expression quantitative trait loci (eQTLs) in 13 tissues via joint

97 and produced the first catalog of expression quantitative trait loci (eQTLs) in a nonhuman primate mo

98 arge-scale epigenomic profiles to expression quantitative trait loci (eQTLs) in a wide range of human

99 of the top signals, we identified expression quantitative trait loci (eQTLs) in whole blood and inves

100 in gene expression are encoded by expression quantitative trait loci (eQTLs) is a key to construct th

101 ociation with disease risk across expression quantitative trait loci (eQTLs) of a gene and use this a

102 Analysis of expression Quantitative Trait Loci (eQTLs) provides modest support

103 The mapping of expression quantitative trait loci (eQTLs) revealed that genetic fa

104 , despite much effort made to map expression quantitative trait loci (eQTLs) that affect the expressi

105 predict causal variants for these expression quantitative trait loci (eQTLs) that disrupt transcripti

106 We performed mapping of expression quantitative trait loci (eQTLs) with WGS and RNA-seq, an

107 expression level of a gene, i.e. expression quantitative trait loci (eQTLs), can help us understand

108 Expression quantitative trait loci (eQTLs), genetic variants associ

109 gene expression levels, known as expression quantitative trait loci (eQTLs), may improve understandi

110 We define these links using expression quantitative trait loci (eQTLs), methylation quantitativ

111 elected archaic haplotypes act as expression quantitative trait loci (eQTLs), suggesting that modulat

112 GWAS loci are also enriched in expression quantitative trait loci (eQTLs), thus suggesting that mo

113 ction allowed detection of 20 206 expression quantitative trait loci (eQTLs).

114 pe-phenotype correlations such as expression quantitative trait loci (eQTLs).

115 ntify over 6000 unique genes with expression quantitative trait loci (eQTLs).

116 8) and influenza virus-and mapped expression quantitative trait loci (eQTLs).

117 idopsis thaliana, uncovering many expression quantitative trait loci (eQTLs).

118 f these variants can be mapped as expression quantitative trait loci (eQTLs); however, a major limita

119 iate mapping model detected 19 heterochronic quantitative trait loci (hQTLs), of which 15 mediate the

120 t enables accurate prediction of methylation quantitative trait loci (meQTL).

121 quantitative trait loci (eQTLs), methylation quantitative trait loci (meQTLs), chromatin conformation

122 ctions, including the mapping of methylation quantitative trait loci (mQTLs) and haplotype-dependent

123 We characterized DNA methylation quantitative trait loci (mQTLs) in a large collection (n

124 Genome-wide scans for module expression quantitative trait loci (mQTLs) reveal five modules with

125 regions (DMRs) and 3,082 strong methylation quantitative trait loci (mQTLs), most not previously rep

126 sity outbred mice, we identify 2,866 protein quantitative trait loci (pQTL) with twice as many local

127 sis of phenotypic traits of interest through quantitative trait loci (QTL) analyses.

128 lection during different life stages, mapped quantitative trait loci (QTL) for fitness and its compon

129 Quantitative trait loci (QTL) for O3 tolerance have been

130 cant involvement of APA in developmental and quantitative trait loci (QTL) gene expression.

131 validated previously reported PPV resistance quantitative trait loci (QTL) intervals, highlighted oth

132 Here, we characterized the "D" locus by quantitative trait loci (QTL) mapping and identified a F

133 Quantitative trait loci (QTL) mapping conducted for deve

134 isms (SNPs) was constructed and utilized for quantitative trait loci (QTL) mapping for salt tolerance

135 on two diverse germplasm panels followed by quantitative trait loci (QTL) mapping in a biparental po

136 dies such as mutation detection, linkage and quantitative trait loci (QTL) mapping, genetic diversity

137 Linkage and quantitative trait loci (QTL) maps are critical tools fo

138 The linkage disequilibrium (LD) based quantitative trait loci (QTL) model involves two indispe

139 and developmental mechanisms underlying most quantitative trait loci (QTL) responsible for floral dif

140 We find that detecting quantitative trait loci (QTL) with HTP phenotyping is as

141 has been investigated by mapping metabolite quantitative trait loci (QTL).

142 We further report on mapping of fruit shape quantitative trait loci (QTLs) and comparison with multi

143 We map quantitative trait loci (QTLs) and find nonadditive QTLs

144 ified significant SNP markers linked to nine quantitative trait loci (QTLs) and simple sequence repea

145 utive and responsive behaviors of two strong quantitative trait loci (QTLs) associated previously wit

146 In addition, we found two quantitative trait loci (QTLs) associated with female ma

147 ssociation study (GWAS) to identify a set of quantitative trait loci (QTLs) for investigating the pat

148 While most cell-type-specific regulatory quantitative trait loci (QTLs) lie in chromatin that is

149 asured using high-throughput DNA sequencing, quantitative trait loci (QTLs) manifest as fragment coun

150 It is known that 250 quantitative trait loci (QTLs) of the grain are associat

151 Mapping of white lupin quantitative trait loci (QTLs) revealed polygenic contro

152 sponses are conferred by series of genes and quantitative trait loci (QTLs) that control complex resi

153 NP markers for genetic map construction, and quantitative trait loci (QTLs) that control differences

154 allele-specific method detected thousands of quantitative trait loci (QTLs) that influenced gene expr

155 enetic variation in yeast has identified key quantitative trait loci (QTLs) that suppress the effects

156 ined RNA-seq data from gingival tissues with quantitative trait loci (QTLs) that were identified in a

157 Five quantitative trait loci (QTLs) were detected that underl

158 sions, we identified two major recombination quantitative trait loci (rQTLs) that explain 56.9% of cr

159 tative trait loci (eQTLs) and 6,768 splicing quantitative trait loci (sQTLs), including 619 new QTLs.

160 ng between sample groups and to map splicing quantitative trait loci (sQTLs).

161 otentially tissue-dependent transcript ratio quantitative trait loci (trQTLs) than SRE SNPs in genera

162 Ps) and genome-wide methylation (methylation quantitative trait loci [mQTLs]) were identified.

163 rdiovascular-related protein levels (protein quantitative trait loci [pQTLs]).

164 The present genome-wide quantitative trait loci analyses explore the cis-regulat

165 expression and methylation were assessed by quantitative trait loci analyses.

166 The expression quantitative trait loci analysis revealed that ERCC1 rs3

167 Expression quantitative trait loci analysis revealed that mRNA leve

168 We mapped cis-acting expression quantitative trait loci and found 24 non-HLA loci that a

169 hich are supported by independent expression quantitative trait loci and gene expression analyses.

170 se substrains and in an F2 cross to identify quantitative trait loci associated with binge eating.

171 We found significant cis-methylation quantitative trait loci at 64% of the 193 CpGs with an e

172 quencies were updated to include the unknown quantitative trait loci based on estimates from the firs

173 Integrating our results with expression quantitative trait loci data, we provide evidence that v

174 GTEx) data set, we implemented an expression quantitative trait loci epistasis analysis to explore th

175 y heart disease at APOB were cis-methylation quantitative trait loci for a low-density lipoprotein ch

176 Although the search for quantitative trait loci for behaviour remains a consider

177 fic structural variants may be causative for quantitative trait loci for germination and resistance t

178 Fifty-two quantitative trait loci for individual and total tocochr

179 ade from 3D plant reconstructions identified quantitative trait loci for standard measures of shoot a

180 lts establish mitochondrial polymorphisms as quantitative trait loci in mammary carcinogenesis, and t

181 We previously discovered 2 overlapping quantitative trait loci in mice, Lsq-1 and Civq-1, that

182 nts for NFAT5 and SLC4A10 are cis expression quantitative trait loci in tissues of the central nervou

183 en of the associated variants had expression quantitative trait loci in whole blood.

184 ovides an important first step to epigenetic quantitative trait loci mapping in genetically identical

185 dentified 18 genomic regions with expression quantitative trait loci of genes correlated with both CA

186 lymorphisms (false discovery rate, 15%) in 4 quantitative trait loci on mouse chromosomes 1, 4, 15, a

187 ese loci competing endogenous RNA expression quantitative trait loci or 'cerQTL', and found that a la

188 uencing gene expression (known as expression quantitative trait loci or eQTLs) is important in unrave

189 A genome-wide quantitative trait loci scan links parasite growth and h

190 f inflammatory markers using cis-methylation quantitative trait loci single nucleotide polymorphisms.

191 However, the identification of additional quantitative trait loci suggests that greater complexity

192 deconvolution of facial forms, we identified quantitative trait loci that are responsible for canine

193 asidiomycete species complex, is linked to a quantitative trait loci that associates with differences

194 dividuals and identified a set of expression quantitative trait loci that contribute to this variatio

195 salt-sensitive (SS) rats identified specific quantitative trait loci that predispose animals to hyper

196 We identified several metabolite quantitative trait loci that reduce variability for both

197 ical variation, and of using DNA methylation quantitative trait loci to refine the functional and reg

198 egions identified contained known expression quantitative trait loci with putative functional consequ

199 On a biological level, eQTL (expression quantitative trait loci) are genetically complex, exhibi

200 In recent years, multiple eQTL (expression quantitative trait loci) catalogs have become available

201 males from 805 DSPR lines, mapping five QTL (Quantitative Trait Loci) that each contribute 4-5 % to a

202 ked enhancers, by the presence of expression quantitative trait loci, and by allele-specific enhancer

203 by performing genetic risk score, expression quantitative trait loci, and variant*ever-smoking intera

204 pproaches, such as the mapping of expression quantitative trait loci, have helped to identify genes,

205 erent chromosomes, and report 934 expression quantitative trait loci, identified in an independent co

206 alf of PEGs were associated with grain yield quantitative trait loci.

207 sert tomato Solanum pennellii and identified quantitative trait loci.

208 We highlight 16 genes based on expression quantitative trait loci.

209 heritable features coincide with expression quantitative trait loci.

210 s expression (eQTLs) and methylation (mQTLs) quantitative trait loci.

211 organ development were located within mapped quantitative trait loci.

212 have identified selective sweeps underlying quantitative trait loci/genes of important fruit quality

213 rs8192675 was the top cis expression quantitative trait locus (cis-eQTL) for SLC2A2 in 1,226

214 tiple-testing correction in local expression quantitative trait locus (cis-eQTL) studies are a trade-

215 dentified protein-altering or cis-expression quantitative trait locus (cis-eQTL) variants in linkage

216 We performed expression quantitative trait locus (eQTL) analyses by using abdomi

217 Using expression quantitative trait locus (eQTL) analyses, we constructed

218 Gene expression quantitative trait locus (eQTL) analysis in 1,425 normal

219 Expression quantitative trait locus (eQTL) analysis in multiple cel

220 Expression quantitative trait locus (eQTL) analysis showed suggesti

221 integrate summary-level GWAS and expression quantitative trait locus (eQTL) data with RNA-seq data f

222 of discoveries have uncovered cis-expression quantitative trait locus (eQTL) effects via mass univari

223 mined a role for rs34481144 as an expression quantitative trait locus (eQTL) for IFITM3, with the ris

224 (RNA-seq)-based approach for both expression-quantitative trait locus (eQTL) mapping and the detectio

225 by a single cis- or trans-acting expression quantitative trait locus (eQTL).

226 We used large DNA methylation quantitative trait locus (mQTL) datasets generated from

227 s been extensively studied using metabolomic quantitative trait locus (mQTL) mapping.

228 A combination of quantitative trait locus (QTL) analysis and genome-wide

229 In this study, we performed quantitative trait locus (QTL) analysis, identified and

230 We used an integrated method of quantitative trait locus (QTL) dissection with a high-re

231 We previously mapped a quantitative trait locus (QTL) for body weight by genome

232 , methylation, and histone variation through quantitative trait locus (QTL) mapping and allele-specif

233 ) to identify, validate and fine-map a major quantitative trait locus (QTL) on wheat chromosome 5A as

234 A quantitative trait locus (QTL) regulating icas#9 sensiti

235 e likely, respectively, to encompass a known quantitative trait locus (QTL) than the rest of the soyb

236 We identified a single quantitative trait locus (QTL) that explains nearly all

237 hat all compounds co-localised with a single quantitative trait locus (QTL) that harbours the FGR gen

238 910083-C was implicated as a cis-methylation quantitative trait locus (QTL) variant associated with h

239 its, and more than 90 independent expression quantitative trait locus (QTL), transcriptome, proteome,

240 Recently, we developed a quantitative trait locus (QTL)-based computational appro

241 a multi-omic resource generated by applying quantitative trait locus (xQTL) analyses to RNA sequence

242 gene expression, 2 papers studied expression quantitative trait locus allelic heterogeneity through c

243 ncluding 1000 Genomes imputation, expression quantitative trait locus analyses, and interrogation of

244 ence, a murine smoking model, and expression quantitative trait locus analyses.

245 Expression quantitative trait locus analysis linked increased COMMD

246 Expression quantitative trait locus analysis of blood pressure loci

247 To prioritize further, we used expression-quantitative trait locus analysis of RNA sequencing from

248 Here we performed quantitative trait locus analysis, utilizing RNA-seq dat

249 Through a trans-expression quantitative trait locus analysis, we provide genetic ev

250 METHODS AND We queried expression quantitative trait locus data acquired in 190 human left

251 We assessed expression quantitative trait locus effects in human lung specimens

252 sue expression consortium for cis-expression quantitative trait locus effects of rs9388451, which rev

253 .124; P<4.5 x 10(-9)), is also an expression quantitative trait locus for BCHE (butyrylcholinesterase

254 brain regions and harbours a cis-expression quantitative trait locus for EFCAB5 (P=3.4 x 10(-20)).

255 Replicable expression quantitative trait locus functionality was identified fo

256 essenger RNA expression and brain expression quantitative trait locus functionality were determined.

257 Using quantitative trait locus mapping and heterologous expres

258 Using an epigenetic quantitative trait locus mapping approach, we were able

259 Quantitative trait locus mapping of a Pla-1 X Col-0 F2 p

260 The application of metabolite-based quantitative trait locus mapping using biparental popula

261 amily-based linkage and association studies, quantitative trait locus mapping, analysis of genome syn

262 rved that this polymorphism is an expression quantitative trait locus modulating CHRNA4 expression le

263 uct marker-assisted selection such that each quantitative trait locus of complex trait is in linkage

264 lymorphism rs4523957, which is an expression quantitative trait locus of the human serine racemase (S

265 96029, this gene was mapped to the site of a quantitative trait locus on Ca5 that explained 59% of fl

266 Focusing on facial shape, we resolved a quantitative trait locus on canine chromosome 1 to a 188

267 We mapped a single genome-wide significant quantitative trait locus on chromosome 11 (logarithm of

268 The quantitative trait locus on distal Chr 13 contained a si

269 ns indicated that the drl loci reside within quantitative trait locus regions for leaf angle, leaf wi

270 on, brain imaging and fetal brain expression quantitative trait locus studies prioritize SLC35B1 and

271 as a positional candidate for an expression quantitative trait locus underlying Borrelia burgdorferi

272 report the cloning and characterization of a quantitative trait locus, GL4, controlling the grain len

273 A quantitative trait locus, qMdr9.02, associated with resi

274 A major quantitative trait locus, Scmv1, has been identified to

275 This imputed expression quantitative trait locus, termed impeQTL, was also shown

276 cted will facilitate QTL and fine mapping of quantitative traits, map-based cloning, comparative mapp

277 CNVs make substantial contributions to quantitative traits, most notably intracellular amino ac

278 ide association studies (GWAS) are robust in quantitative trait nucleotide (QTN) detection, the absen

279 e the state-of-the-art procedure to identify quantitative trait nucleotides (QTNs) associated with co

280 l tests were conducted to identify imprinted quantitative trait nucleotides (QTNs) associated with re

281 The authors interrogated a quantitative trait of CP (mean interproximal clinical at

282 reasingly being modeled as a function of the quantitative traits of species, which are used as proxie

283 sk SNPs underlying complex human phenotypes (quantitative traits or diseases).

284 gh changes in gene expression that influence quantitative traits, or through the regulation of the ep

285 A quantitative trait (QTL) mapping approach was applied an

286 eotide polymorphisms (SNPs) and neuroimaging quantitative traits (QTs) is one major task in imaging g

287 single nucleotide polymorphisms (SNPs)) and quantitative traits (QTs) such as brain imaging phenotyp

288 approximately 3,000 individuals we obtained quantitative traits related to 9 of the ordinal phenotyp

289 20 different genetic association studies for quantitative traits related to complex diseases, conduct

290 e association of them with pre-eclampsia and quantitative traits relevant for the disease.

291 H9308) was constructed for identification of quantitative trait SNPs (QTSs) associated with two impor

292 aditional models of GxE in a case-control or quantitative trait study as well as alternative approach

293 ently limited by incremental improvements in quantitative traits that often rely on laborious selecti

294 ortant traits, (b) deepened understanding of quantitative traits through new analytical models and po

295 nd it required 1.75 hr for the analysis of a quantitative trait using several rare variant aggregate

296 Mapping gene expression as a quantitative trait using whole genome-sequencing and tra

297 derpinning variant association with platelet quantitative traits using cell type-matched epigenomic d

298 ting genetic interactions that contribute to quantitative trait variation in a large yeast intercross

299 better represent the genetic architecture of quantitative traits, which likely involve some large eff

300 nd provide desirable prediction accuracy for quantitative traits, with universal applications under w