ライフサイエンスコーパス: question

1 ion (a three-item scale) and loneliness (two questions).

2 ,5'-cAMP might provide new insight into this question.

3 ers metabolon formation has remained an open question.

4 subsequently inserts into the NE is an open question.

5 eceptor), as our model system to tackle this question.

6 o this challenge is, for some, still an open question.

7 o control emergency hematopoiesis is an open question.

8 d case law of the particular jurisdiction in question.

9 e vast molecular space remains an unanswered question.

10 on, which cannot be related to the period in question.

11 equired for error-prone synthesis is an open question.

12 phenotypic diversity remains a hotly debated question.

13 y drive morphogenesis remains an outstanding question.

14 provide an appropriate system to study this question.

15 available tools do not directly address this question.

16 ro-vibrational line list of the molecule in question.

17 s the proportion of affirmative answers to a question.

18 hibitory neurons may be able to resolve this question.

19 cal analysis that provides an answer to this question.

20 ed to assess for TCS phobia included 1 to 69 questions.

21 asic microbiological and clinically relevant questions.

22 discipline and the topics on the examination questions.

23 these processes through task instruction or questions.

24 Finally, we present outstanding questions.

25 ls completed rounds 1 and 2 and suggested 15 questions.

26 d preclude their understanding of the survey questions.

27 been investigated, sometimes with lingering questions.

28 provide promising new hints to answer these questions.

29 ggered in physiological settings are ongoing questions.

30 opulation, Intervention, Comparison, Outcome questions.

31 clear, with several long-standing unanswered questions.

32 l muscle stem cells (MuSCs) to address these questions.

33 pulated by a series of highly individualised questions.

34 unnel", the carotenoids still pose many open questions.

35 eport a 'good enough' solution to biological questions.

36 across 120 sites on 20 farms to answer three questions.

37 ch reporting accuracy and fishery management questioned.

38 uality of the evidence to address 3 research questions: (1) How accurate is teledermatology for skin

39 METHODS AND To address the question, 2 transgenic mouse models were generated: a ph

40 An important question about color vision is how does the brain repres

41 c span of our sampling to address intriguing question about the place of origin of Russian Starovers,

42 by advances in microscopy that helped answer questions about cell biology but also by clever genetic

43 xperimentalists to ask otherwise intractable questions about chromosome structure, function, and evol

44 shows promising results and raises important questions about gene expression and the epigenetics of G

45 Interobserver agreement was fair regarding questions about glaucoma progression (kappa, 0.39; 95% C

46 ontinue to provide insights into fundamental questions about how aromatic compounds behave.

47 This raises important questions about how the assembly of IL-12 family members

48 in nonhuman animals, we are left with major questions about how the disposition to think analyticall

49 We have begun to ask questions about how these cells can be regulated to miti

50 imuli and simplified behaviors, leaving open questions about nervous system function in the context o

51 (NAC) for operable breast cancer has raised questions about optimal local therapy for the axilla.

52 offer opportunities to address long-standing questions about the establishment of effective B cell im

53 There are many unanswered questions about the evolution of the ancient 'Silk Roads

54 GWASs) make it possible to address important questions about the genetic architecture of complex trai

55 matic amino groups in metabolites and raises questions about the intermediacy of this species in kina

56 ne for GRN evolution, is necessary to answer questions about the rate at which GRNs and their subcirc

57 developed a causality framework that defined questions about the relationship between Zika virus infe

58 y and compartmentalization of neurons raises questions about the spatial and temporal regulation of g

59 stat in mild-to-moderate AD raises important questions about the timing of intervention with BACE-1 i

60 Respondents were asked questions about their perpetration or experience of inti

61 have their own scoring systems, which raises questions about their similarity and the potential inter

62 To resolve unanswered questions about these inhibitors, we developed a novel a

63 prevention and treatment, there remain many questions about this decline.

64 the spread of signals between cells, raising questions about whether PD are in different functional s

65 The same questions addressed by IOM-compliant pulmonary or critic

66 We weigh in on this question and demonstrate that when those sequence elemen

67 ing contact sessions, as well as via online "question and discussion" forums outside of contact sessi

68 Here, we provide an overview of the key questions and challenges in the field, aiming to (1) pro

69 c tractability, but by ecologically relevant questions and hypotheses.

70 model for FUS LCD fibrils that answers some questions and raises new ones.

71 die in the ICU often remain with unanswered questions and suffer from lack of closure.

72 l types of proactive policing, such as stop, question, and frisk.

73 e sample of physician mothers completed a 45-question anonymous, secure, online questionnaire regardi

74 Although the answers to all of these questions are not yet available, rapid progress in combi

75 Clinical Question: Are different opioid agonist treatments (eg, m

76 It has been a long-standing question as to whether the activation of Notch by its li

77 ic tools by allowing them to formulate their questions as free text.

78 n a large number of different sHsps, raising questions as to whether they function redundantly or are

79 However, the underlying evidence may be questioned, as the obvious correlations between various

80 hod is appropriate to address all biological questions, as each variant differs markedly in resolutio

81 The most common question asked by patients with inflammatory bowel disea

82 empirical research aimed at addressing these questions at the level of psychological process and neur

83 This is an important question because subdominant TCD8 are more likely than i

84 es, often leading to the hormone/mediator in question being dismissed as a potential obesity therapy.

85 modeling (ENM) has been used to address such questions, but improvements and debate in study design,

86 Here, we attempt to address this question by applying a machine learning technique to SP

87 We answer this question by developing a statistical function which desc

88 , building on previous work, we address this question by testing whether a preconditioned cue will su

89 We investigated this question by using Independent Components Analysis to obt

90 Here, we answer this longstanding question by using transgenic Hydra expressing fluorescen

91 the efficacy of all the other strategies was questioned by restricting the analysis to high-quality t

92 Here we addressed these questions by identifying degradation signals in RGS2, an

93 These questions can be addressed with genomic data, which can

94 mic, and hierarchical systems, many research questions cannot be answered statistically without stron

95 ture and hydrodynamics remains a fundamental question concerning biofilm dynamics.

96 A longstanding question concerns the structure of the C-terminal region

97 nternational Cardiac Arrest Registry), an 87-question data set representing 44 centers in the United

98 e 3 trial that might potentially answer this question definitively.

99 When 70% agreement was required, 17.9% of questions did not yield recommendations, but for those t

100 ere available via video conferencing to take questions during contact sessions, as well as via online

101 To explore these questions, experimental platforms are needed that can ex

102 opulation, Intervention, Comparator, Outcome questions, five quality of evidence statements, and one

103 d life style characteristics, and diagnostic questions following Rome III criteria to assess IBS occu

104 Here we address this question for extracellular signal regulated kinase (Erk)

105 e eddy-covariance systems, which must now be questioned for their accuracy in desert ecosystems.

106 eneral practice appointments raise important questions for both the management of patients who miss m

107 g of a host of important biomedical research questions for which hamsters are an excellent model.

108 Answers to this question from theoretical and empirical perspectives are

109 hest stress)) was computed on the basis of 2 questions from the Perceived Stress Scale.

110 This is an important question, given the increasing realization that toxicity

111 To address this question, heterozygous ERalpha knockout (WT/KO) dams wer

112 Recent findings question histology- and imaging-based definitions of the

113 r initiation raised two important unanswered questions: how do PGCCs acquire such stemness, and to wh

114 In this research, we question if strong identification with an in-group neces

115 We addressed this question in a parallel genetic study between the closely

116 Metabolomics answers a fundamental question in biology: How does metabolism respond to gene

117 n through formation of new organs is a major question in developmental biology.

118 ctors to shape organogenesis is an important question in developmental biology.

119 A key and challenging question in evaluating the data was determining the cont

120 A long-standing question in evolutionary developmental biology is how ne

121 emissions on health has been a long-standing question in human health sciences; however, the toxicolo

122 capacity for sensory uptake is a fundamental question in neuroscience.

123 of Cordilleran plateaus remains a lingering question in part because of the inherent difficulty in q

124 Here, we have addressed this question in the Gram-negative model bacterium Burkholder

125 acceptor interfaces has been a long-standing question in the organic photovoltaics community.

126 itable mechanism has become a key unanswered question in the origin of life.

127 used theory and experiments to address this question in the pathogenic bacterium, Pseudomonas aerugi

128 We studied this question in young, healthy human participants (both sexe

129 iting opportunities to address long standing questions in biomedical research.

130 iew provides a framework to tackle lingering questions in DUB biology.

131 the use of preexisting data sets to address questions in ecology.

132 roaches are being used to answer fundamental questions in embryology, such as how cells self-organize

133 egun adopting SRM to address a wide range of questions in many types of specimens.

134 lly relevant conditions-answer long-standing questions in membrane biology and illustrate a fundament

135 ne expression, thereby answering fundamental questions in neurobiology.

136 st, I naively ask: Is the great diversity of questions in neuroscience best studied in only a handful

137 so point out some of the most important open questions in the field and emerging evidence suggesting

138 Important questions include what defines the size of a population

139 Answering this question is challenging because human time scales set a

140 A fundamental question is how generalist pollinators recognize "flower

141 One unresolved question is how RLRs interact with each other and with v

142 An open and unresolved question is how STRF maturation affects stimulus-evoked

143 A key question is how the variety of available protocols compa

144 One question is to determine whether OCN is also sufficient

145 A pressing question is to what extent results from visual studies g

146 A further interesting question is whether B-derived transcripts become functio

147 An ongoing question is whether CENH3 evolution is driven by a funct

148 However, a remaining clinically relevant question is whether early post-status epilepticus (SE) e

149 One key question is whether speech-plus-gesture and sign-with-ic

150 An important outstanding question is whether the antOFC and vlPFC act on common o

151 n of these formulas motivates an interesting question: Is there an optimal feedback strategy to regul

152 f unanswered scientific, ethical, and policy questions, it is inappropriate to perform germline gene

153 ential for drug overdose treatment without a question mark on the timing used in the animal models.

154 networks that vary considerably in size and questions: movements of an endangered raptor, the snail

155 The following questions need to be answered in this regard: are there

156 zed evidence from studies investigating this question, no review to date has explored specific eviden

157 In this framework, we consider the question of cell types in medial entorhinal cortex (MEC)

158 other experiments to address more fully the question of FliG number.

159 The fundamental question of how bone quality is affected in AIS remains

160 hbours are observed, and poses a fundamental question of how complex interactions on the triangular l

161 of p38 MAP kinase, which posed the important question of how Epac2 engages p38 without simultaneously

162 Threshold-seq addresses the critical question of how many reads need to support a short RNA m

163 The question of how noncoding RNAs are involved in Polycomb

164 Here we address the question of how rapidly multiple drivers of marine ecosy

165 chanism that triggers uncoating is a pivotal question of long standing.

166 To investigate the question of ongoing viral replication on current ART reg

167 We focus here on the question of size regulation in bacteria, and suggest tha

168 this review, we have addressed not only the question of the application of chemometrics for aroma an

169 This raises the question of the ecosystem's systemic resilience and its

170 Our results answer the long standing question of the physical mechanisms driving cell sorting

171 f large-scale human functional networks, the question of timing, stability, and direction of communic

172 le meiosis in most animals, which raises the question of what prevents the sperm DNA from interacting

173 This state of equipoise raises the question of whether alternative anticoagulants may have

174 during differentiation, raising an important question of whether downregulation of COUP-TFII expressi

175 This helps unravel the oft-debated question of whether silk is pushed or pulled from the an

176 on, and dispersal, prompting the tantalizing question of whether social diversity may also be a conse

177 xcitation is weak in adult mice, raising the question of whether the primary role of this pathway may

178 We address the crucial question of whether the seven Earth-sized planets transi

179 l of microstructural plasticity, raising the question of whether this contributes to adaptive evoluti

180 n critically ill elderly patients has led to questioning of the beneficial effect of intensive care u

181 r analysis of the key uncertainties and open questions of and beyond the inventory shows that, among

182 ndividual studies to address macroecological questions of bacterial diversity remains methodically ch

183 ternal validity and turning its attention to questions of external validity.

184 ample, the sequencing methodology and on the questions of interest.

185 Here, we address these questions on shoals of Hemigrammus rhodostomus, a specie

186 type of SI is the predominant one concerning questions on the understanding of science, the main goal

187 al and precentral gyri immediately following question onset; at the same time, high-gamma activity wa

188 opulation, Intervention, Comparator, Outcome questions or quality of evidence statements.

189 association study (GWAS) of responses to the question, 'Over the last two weeks, how often have you f

190 Questions persist, however, about how individual structu

191 patient instructors while patients received question prompt lists and individualized communication c

192 c regulators in humans raises an interesting question regarding how chromatin dysregulation contribut

193 ntify adults with a history of AD, we used a question regarding physician-diagnosed AD and 2 versions

194 e of these control costs also raises further questions regarding how best to allocate mental effort t

195 lied to disparate molecular systems, raising questions regarding the compatibility of the results.

196 iciary from the lactate, neurons-prompts new questions regarding the controversial role of lactate in

197 aging of corneal nerves in vivo are spawning questions regarding the relationship between corneal ner

198 ithin the cytoplasm of animal cells, raising questions regarding the relative roles of viral and host

199 We also discuss major unanswered questions regarding the role that defects in ciliary com

200 A crucial, yet open, question regards how babies deal with stimuli experience

201 ularly applicable to catalytic systems where questions related to homogeneous vs heterogeneous pathwa

202 inally, we discuss major challenges and open questions related to the application of SERS for underst

203 onal recommendations regarding four specific questions related to the diagnosis of LAM and management

204 Despite their functional importance, several questions remain about how these proteins are assembled

205 ad cellular impact of SCF enzymes, important questions remain about the architecture and regulation o

206 Questions remain about the degree to which aerosols are

207 However, questions remain as to the impact of CBIs on nutritional

208 However, important questions remain regarding the biogenesis and function o

209 lication occurs in a precise order, but many questions remain regarding the mechanisms of replication

210 However, questions remain regarding the optimal methods of biosti

211 However, important questions remain surrounding the specific changes and pr

212 However, many important questions remain unclarified.

213 e body of research, many basic epidemiologic questions remain unsolved.

214 as, and Stentor coeruleus Although many open questions remain, elucidating how cells repair themselve

215 nt has long been appreciated, but many basic questions remain, such as what initiates or terminates t

216 g and spin polarization, for which many open questions remain.

217 The questions remained (a) whether the plaque phenotype in t

218 is and processing have been elucidated, many questions remained, such as the structure-function relat

219 But an outstanding question remains: what principle tells us which state va

220 Seven questions required respondents to interpret BCID results

221 ce-to-Decision framework was applied to each question, requiring the panel to evaluate and weigh the

222 To address this question, research to date generally has focused on corr

223 nanotubes (CNTs) has been an important open question since the first reports of the strong modulatio

224 have been used to address the full range of questions studied by agricultural entomologists, enabled

225 This obscures answers to key questions, such as how tetrapods attained their tremendo

226 paper focuses on the most relevant clinical questions, summarises the results of recent clinical tri

227 al, and initial (test 1) and additional test questions (test 2) into each chapter.

228 anges over time, thus expanding the range of questions that can be addressed in adult zebrafish and o

229 One of the enduring questions that has driven neuroscientific enquiry in the

230 each other in time and space are scientific questions that intrigue me.

231 tions of human AML LSCs and discuss critical questions that need to be addressed in future research.

232 Two questions that presented the risk of AK as not progressi

233 For clinical questions that were not addressed by the AABB and the In

234 ed at different spatial scales, calling into question the appropriate jurisdictional level at which t

235 rsus posterior parietal cortex, calling into question the broader assumption that the alpha rhythm ma

236 hough it is reasonable and necessary that we question the relevance of such small effects, we present

237 of the cellular prion protein, leading us to question the role of fH in prion disease.

238 lular enzymes that degrade SOM, calling into question the ubiquity of the proposed mechanism.

239 The findings question the value of this operation for these indicatio

240 Our findings call into question the view that motion processing deficits are du

241 Previous work has questioned the effect of population-level deworming; how

242 Reports have questioned the technical proficiency of newly graduating

243 ll biological studies have shed light on the question-the site of BDNF release at the synapse.

244 The question thus arises whether there are instances where t

245 This is an important question to answer because stimulus-evoked correlated ac

246 In this paper we pose the question to what extent sequence- and structure-informat

247 am recipients' self-efficacy in knowing what questions to ask their doctor significantly improved at

248 ed tonic signaling heterogeneity remain open questions today.

249 les, presenting a macroevolutionary angle to questions traditionally explored at microevolutionary sc

250 The sensitivity of the check-all-that-apply questions, treating the forced-choice format as the "gol

251 To address this question, unmedicated individuals with pathological anxi

252 Here we address the question using a comparative approach to contrast divers

253 Here, we address this question using the network controlled by the fungal tran

254 hallenged previous attempts to resolve these questions using conventional genetic techniques.

255 -nucleotide polymorphisms for this tiredness question was 8.4% (s.e.=0.6%).

256 on skills, evidence for many of the clinical questions was limited.

257 To address this question, we analysed the performance of two groups of p

258 To address this question, we assessed whether petal number responds to a

259 To address this question, we built an up-to-date and complete database o

260 To investigate this question, we compared the fate of IgE-ICs in human B cel

261 To investigate this question, we developed breast cancer cell lines expressi

262 To address this question, we engineered a mutant of MYO6, MYO6+, which u

263 To address this question, we exploited a prion conversion in vitro assay

264 To address this question, we generated a novel Drosophila model expressi

265 To address this question, we generated Cic-deficient mice and human olig

266 To investigate this question, we obtained an effect estimate, which can have

267 To address this question, we performed comparative transcriptomics analy

268 To address this question, we recorded neural activity in a prefrontal se

269 To investigate this question, we studied performance during an explorative m

270 To address this question, we studied two pathways originating from the p

271 To investigate this question, we use a CRISPR-dCas9 epigenetic editing tool,

272 To address this question, we used functional near-infrared spectroscopy

273 To answer this question, we used psychoacoustic tests and comparative a

274 To address this question, we used the Atonal family of proneural transcr

275 To tackle these questions, we carried out a series of behavioral experim

276 To address these questions, we developed a quantitative polymerase chain

277 Addressing these questions, we find that VEGF acts as a survival factor i

278 To investigate these questions, we have studied the behaviour of single-cryst

279 To answer these questions, we recorded intracellularly from hippocampal

280 To answer these questions, we tested for differentiation, movement and e

281 To address our questions, we took advantage of a population of Magnific

282 Other prespecified research questions were addressed qualitatively.

283 Questions were asked about: use of ayahuasca, lysergic a

284 ewed, research gaps were identified, and key questions were generated for each of three research doma

285 of the studies performed so far answered the question what size of the defect should be an indication

286 described here, we have asked the following question: what fraction of the rotavirus particles that

287 However, a critical question when analyzing high-dimensional and heterogeneo

288 istance (IR), and dementia has recently been questioned, wherefore the aim of this study was to asses

289 unknown 12-epi-hapalindole U (3), raised the question whether 3 is a direct precursor to 4 or an arti

290 We question whether implicit memory for language can and sh

291 In particular, it remains an open question whether metacognitive judgments are based on th

292 This raises the question whether PAP thereby affects the expression and

293 nics of retromer-based sorting and call into question whether retromer indeed functions as a complex

294 y investigates the controversially discussed question whether this attention effect extends to imperc

295 he genes downregulated by JAK2 knockdown, we questioned whether TFEB is regulated by JAK2.

296 This questions whether the available x-ray crystal structures

297 been studied extensively, it remains an open question why microvessels need to be so narrow.

298 Moving forward, answers to these questions will provide a greater level of understanding

299 In each project, we sought questions with the precision needed for economic modelin

300 als were for secondary hypothesis-generating questions, with only 1 proposed reanalysis of the origin