ライフサイエンスコーパス: queuosine

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1 biosynthesis of the tRNA-inserted nucleoside queuosine.

2 1), the precursor to the modified nucleoside queuosine.

3 aguanine, a late step in the biosynthesis of queuosine.

4 step that also causes hydrolysis of glutamyl-queuosine.

5 biosynthesis of the hypermodified nucleoside queuosine.

6 sor to the essential hypermodified tRNA base queuosine.

7 for enzymes involved in the biosynthesis of queuosine, a 7-deazaguanine modified nucleoside found in

8 as an enzyme involved in the biosynthesis of queuosine, a 7-deazaguanosine modified nucleoside found

9 se to the intracellular concentration of the queuosine anabolic intermediate preQ(1).

10 es bacteria and the hypermodified tRNA bases queuosine and archaeosine.

11 Given that GTP is the precursor to queuosine and that a cyclohydrolase-like reaction was po

12 preQ(1) riboswitch allows the fine-tuning of queuosine biosynthesis in response to the intracellular

13 bacter confirmed that each was essential for queuosine biosynthesis, and the genes were renamed queCD

14 action was postulated as the initial step in queuosine biosynthesis, QueF was proposed to be the puta

15 s downstream encoded modification enzymes of queuosine biosynthesis.

16 nthase (PTPS) homologue possibly involved in queuosine biosynthesis.

17 on of pre-Q(0) to pre-Q(1) in the nucleoside queuosine biosynthetic pathway.

18 RNA anticodon modification from guanosine to queuosine has coevolved with these genomic changes.

19 Glutamyl-queuosine, like canonical Glu-tRNA, was hydrolyzed by mi

20 mechanism to harness exquisite control over queuosine metabolism.

21 Levels of queuosine modification in D. melanogaster reflect bioava

22 Queuosine modification is present in most organisms but

23 that are most accurate given stage-specific queuosine modification levels.

24 ne transglycosylase (TGT) is involved in the queuosine modification of tRNAs in eukarya and eubacteri

25 netic model, the known increased affinity of queuosine-modified tRNA for ribosomes increases the accu

26 l-7-deazaguanine (preQ1), a late step in the queuosine pathway.

27 Queuosine (Q) and archaeosine (G(+)) are hypermodified r

28 ia coli that contain the modified nucleotide queuosine (Q) at the wobble position, thereby preventing

29 li that contain the hypermodified nucleoside queuosine (Q) at the wobble position.

30 One nearly universal modification is queuosine (Q) for guanine (G) in tRNA(His), tRNA(Asp), t

31 Queuosine (Q) is a 7-deazaguanosine found in the first p

32 Queuosine (Q) is a hypermodified 7-deazaguanosine nucleo

33 Queuosine (Q) is a hypermodified base found in the wobbl

34 Queuosine (Q) is a hypermodified RNA base that replaces

35 The modified nucleotide queuosine (Q) is almost universally found in the anticod

36 discoideum, are strongly stimulated by prior queuosine (Q) modification of the substrate tRNA.

37 Queuosine (Q) was discovered in the wobble position of a

38 nthesis of the hypermodified tRNA nucleoside queuosine (Q), an unprecedented ribosyl transfer from th

39 in tRNAs from a G in the wobble position to Queuosine that changes optimal binding from C to a sligh

40 ree precursor in the biosynthetic pathway of queuosine that is crucial for translation efficiency and

41 (4,5-dihydroxy-2-cyclopenten-1-yl) moiety of queuosine, the modified nucleoside occupying the first a

42 t of preQ1, a precursor of the modified base queuosine universally found in four tRNAs.

43 deazaguanosine have been identified in tRNA: queuosine, which is found at the wobble position of the

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