ライフサイエンスコーパス: quiescent

1 FSCs, but Hh also signals to ECs, which are quiescent.

2 is was unaffected and residual HSCs remained quiescent.

3 in embryo (Strongylocentrotus purpuratus) is quiescent.

4 render and maintain endothelial stalk cells quiescent.

5 er the G0 phase of the cell cycle and become quiescent.

6 These observations show that quiescent ABCs are Ag-experienced cells that accumulate

7 t the differentiated phenotype of ordinarily quiescent adult glomerular podocytes.

8 r CDKN1A/p21 facilitates cell cycle entry of quiescent adult human pancreatic beta cells.

9 on of slowly dividing RGCs gives rise to the quiescent adult NSCs that populate the ventricular-subve

10 a transmembrane protein previously found in quiescent adult NSCs, is expressed by a subpopulation of

11 ighly proliferative embryonic stem cells and quiescent adult stem cells, with a focus on hematopoieti

12 uPA-T recognizes human alphaIIbbeta3 on both quiescent and activated platelets and is enzymatically a

13 lony formation and proliferation of purified quiescent and activated V-SVZ stem cells and transit-amp

14 lifying cells and neuroblasts) but not NSCs (quiescent and activated) undergo apoptosis after 2 Gy IR

15 exhibiting a novel bistable regime between a quiescent and an inhibition-stabilized state of arbitrar

16 pression and VEGF/VEGFR2 pathway activity in quiescent and angiogenic blood vascular endothelial cell

17 ng magnetic fields to explain their observed quiescent and bursting emission, implying that the field

18 that persistent residual leukemic cells are quiescent and can become responsive to the treatment whe

19 the horizontal basal cells (HBCs), which are quiescent and held in reserve, and mitotically active gl

20 in tissues with little turnover, are largely quiescent and only activate in response to regenerative

21 lted in dual cellular synthetic lethality in quiescent and proliferating immature leukemia cells, and

22 Quiescent and proliferating leukemia cells accumulate hi

23 stochastic chromatin opening mostly found at quiescent and repressed sites.

24 lassical theory of a linear hierarchy, where quiescent and slowly-cycling stem cells self-renew but r

25 nd the vessels, and phalanx cells, which are quiescent and support the sprout.

26 Lack of PDK1 caused HSCs to be less quiescent and to produce a higher number of phenotypic H

27 gs) induced during autoimmunity often become quiescent and unable to resolve disease, suggesting inad

28 ain clusters with distinct features: active, quiescent, and an un-characterized cluster.

29 n of stress granules (SGs) in proliferating, quiescent, and differentiated muscle cells, as shown by

30 he tumor spheroids (layers of proliferating, quiescent, and necrotic cells).

31 es previously considered to be metabolically quiescent are, in fact, active and able to adapt their c

32 Drosophila neural stem cells (NSCs) are quiescent at early larval stages, when they are reactiva

33 y responses and the engagement of previously quiescent autoreactive T cells and B cells.

34 receptor in muscles and neurons to suppress quiescent behavior and promote roaming in fasting worms,

35 Replicating Lgr5(+) stem cells and quiescent Bmi1(+) cells behave as intestinal stem cells

36 of TAC-derived progenitor cells, rather than quiescent bulge SCs, for anagen HF repair can be a poten

37 rsistence of a pool of cancer cells that are quiescent but alive.

38 n their normal microenvironment are far from quiescent, but are capable of generating substantial Ca(

39 Healthy PSCs are quiescent, but upon activation during disease progressio

40 stem cells in vivo, which are predominantly quiescent, by generating pseudotyped-lentivirus.

41 state and generates a rebound effect pushing quiescent cancer cells back into the cell cycle, both in

42 prevalence of HP infection in patients with quiescent CD is relatively low.

43 XCL11, and CXCL13) were upregulated in human quiescent CD34(+)Hoescht(-)Pyronin Y(-) and primitive CD

44 ating (CDK2-increasing) versus spontaneously quiescent (CDK2-low) cells, including Cyclin D1, the lev

45 status with a high proportion of cells in a quiescent cell cycle phase as assessed in wounds, tumors

46 m cell stage and remained in the marrow in a quiescent cell cycling state (G0).

47 center, and its inactivation leads to fewer quiescent cells and a smaller bud.

48 odifications can be dynamically regulated in quiescent cells and that epigenetic reprogramming can im

49 o-stratified epithelia through activation of quiescent cells and/or a switch in cell-fate determinati

50 ith an up to 43% increase in the fraction of quiescent cells as compared with cells grown in standard

51 Through this mechanism, quiescent cells avoid the accumulation of aged long-live

52 Surprisingly, in quiescent cells Exportin-1-dependent pri-miR-34a is pres

53 ations in the bone marrow and a reduction in quiescent cells in G0 Surprisingly, the loss of classica

54 Quiescent cells in nondormant dry embryos are reawakened

55 S is sufficient to promote the transition of quiescent cells into senescence and preventing repressio

56 Quiescent cells play a predominant role in most organism

57 Quiescent cells take up sufficient nutrients to sustain

58 o weeks after infection and is maintained by quiescent cells that divide less than once every year (d

59 Reactivating quiescent cells to proliferate is critical to tissue rep

60 sponses, naive T cells transition from small quiescent cells to rapidly cycling cells.

61 on-induced stress response factors may prime quiescent cells to reenter growth through glycolysis whe

62 We showed that metacyclics are quiescent cells, and propose this influences the choice

63 In quiescent cells, the interaction between WASF3 and a com

64 In quiescent cells, the primary cilium insulates itself fro

65 reaction targeting AURKA for degradation in quiescent cells, where degradation of AURKA is required

66 tive regions may be a source of mutations in quiescent cells.

67 nguish the behaviour of recently divided and quiescent cells.

68 tubule bundle that specifically assembles in quiescent cells.

69 ein that exists in an autoinhibited state in quiescent cells.

70 ly refreshed by occasional divisions of more quiescent cells.

71 ittle is known about proteasome functions in quiescent cells.

72 pproaches to reactivate latent infections in quiescent cells.

73 the release of RNA polymerase in cycling and quiescent cells: (i) RNA polymerase II release mediates

74 cells have long been regarded as relatively quiescent cells; however, it was recently shown that IL-

75 atopoietic stem cells (HSC), which provide a quiescent cellular reserve.

76 for root meristem organization, the onset of quiescent center (QC) formation during lateral root morp

77 apical meristem, a group of slowly dividing quiescent center cells is thought to limit stem cell act

78 (PAN) as an important molecular regulator of quiescent center function.

79 d that ABA accumulated in the endodermis and quiescent center of Arabidopsis thaliana root tips, mimi

80 at occur as cells move further away from the quiescent center.

81 oot apical meristem (RAM) size and defective quiescent centre (QC) development.

82 ct evidence that TPCs can reversibly enter a quiescent, chemoresistant state and thereby underscore t

83 hat non-chitinolytic bacteria can activate a quiescent ChiP gene to express a functional chitoporin,

84 e the characteristics and natural history of quiescent choroidal neovascularization (CNV) in geograph

85 the identification of a population of highly quiescent chronic myeloid leukemia (CML) SCs that is enr

86 an to noninvasively identify treatment-naive quiescent CNV and may be considered as a useful tool to

87 On ICGA, quiescent CNV appeared as a distinct area of hyperfluore

88 Quiescent CNV appeared as an ill-defined hyperfluorescen

89 Sensitivity and specificity of quiescent CNV detection by OCT-A turned out to be 81.8%

90 At last follow-up, 92% of the quiescent CNV seemed to cover the area spared from atrop

91 etinal pigment epithelium at the site of the quiescent CNV visualized by structural OCT.

92 Patients diagnosed with quiescent CNV were analyzed in 2 high-volume referral ce

93 Treatment-naive quiescent CNV were identified from a pool of patients at

94 nty-two eyes of 20 consecutive patients with quiescent CNV were included.

95 The characteristics of the quiescent CNVs were very similar to those already descri

96 osa LasI/R QS systems in bacteria exposed to quiescent conditions and controlled flows.

97 t QS onset in both systems was similar under quiescent conditions but markedly differed under flow.

98 Under quiescent conditions where fibril breakage is minimal, f

99 is mildly agitated or within three hours in quiescent conditions.

100 sion persisted but was undetectable in fully quiescent differentiated cells or senescent cells.

101 Consecutive CD patients with quiescent disease underwent meticulous disease evaluatio

102 uring routine clinical care in patients with quiescent disease) compared with no routine TDM.

103 f HP in a selected group of CD patients with quiescent disease, and to assess the influence of its er

104 n active disease or prevention of relapse of quiescent disease, with 95% CIs.

105 tomised into those with clinically active or quiescent disease, with 95% CIs.

106 when compared with control in patients with quiescent disease.

107 trol at the end of therapy for patients with quiescent disease.

108 th ICG-001 results in the differentiation of quiescent drug-resistant chronic myelogenous leukemia-in

109 erpes simplex keratitis (HSK group) that was quiescent during evaluation (no acute episode in the pas

110 rveys have revealed the presence of massive, quiescent early-type galaxies appearing as early as reds

111 SPARCL1 expression was induced in confluent, quiescent ECs and functionally contributed to EC quiesce

112 SPARCL1 secretion from quiescent ECs inhibited mural cell migration, which like

113 Here we show that endomucin abrogation on quiescent endothelial cells enables neutrophils to adher

114 y gland, the identity and characteristics of quiescent epithelial stem cells are not clear.

115 is in PDGF-activated fibroblasts, but not in quiescent fibroblasts.

116 on and re-orientation confinement found in a quiescent flow, and consequently enhances surface normal

117 Normally quiescent, following muscle fiber injury, we show that t

118 The biology of this quiescent form of the parasite is poorly understood whic

119 hat the Hippo pathway activity discriminates quiescent from non-quiescent NSCs in the Drosophila nerv

120 ing with cell-surface markers to distinguish quiescent from proliferative TPCs within SCCs.

121 of flow begin to deviate from an apparently quiescent fully formed state in spite of steady backgrou

122 fic mRNAs are translationally upregulated in quiescent (G0) mammalian cells and immature Xenopus laev

123 set of SP T cells (Tsp cells) that exhibit a quiescent (G0) phenotype in humans and mice.

124 However, we found that, in quiescent (G0) rat myoblasts transiting to the G1 phase,

125 However, these early, massive, quiescent galaxies are not predicted by the latest gener

126 eported evidence for populations of massive, quiescent galaxies at even higher redshifts and earlier

127 10(10) times that of the Sun; the number of quiescent galaxies has increased by a factor of about 25

128 resence of centrally driven winds in typical quiescent galaxies that host low-luminosity active nucle

129 Quiescent galaxies with little or no ongoing star format

130 robed by combining the spectra of 24 massive quiescent galaxies, yielding an average [Mg/Fe] = 0.31 +

131 eport a measurement of [Mg/Fe] for a massive quiescent galaxy at a redshift of z = 2.1, when the Univ

132 pproach to identify structural properties of quiescent glasses and relate them to glassy dynamics.

133 In contrast, the normally quiescent HBCs are activated to multipotency and prolife

134 ombination-driven deletion of Dnmt1 in adult quiescent hepatocytes did not affect liver homeostasis.

135 a transient induction of S-phase entrance by quiescent hepatocytes, indicating that Grb14 is a potent

136 e the quality of life (QoL) in patients with quiescent herpes simplex keratitis compared with control

137 s did not correlate to mRNA level changes in quiescent HFSCs.

138 enforce the expression of viral antigen from quiescent HIV-1 genomes, and immunotherapies to clear la

139 for low-level fibrogenic gene expression in quiescent HSCs and causes dampened gene expression in ac

140 ssed RAS (ERAS) is specifically expressed in quiescent HSCs and down-regulated during HSC activation

141 Exosomes from quiescent HSCs caused miR-199a-5p-dependent inhibition o

142 poietic stress, although reported to recruit quiescent HSCs into cycle, was well tolerated by HSPC-de

143 is characterized by trans-differentiation of quiescent HSCs to HSC myofibroblasts, which secrete extr

144 ereby investigated the signaling networks of quiescent HSCs versus activated HSCs.

145 Our data strongly indicate that in quiescent HSCs, ERAS targets AKT via two distinct pathwa

146 Notably, in quiescent HSCs, the high level of ERAS protein correlate

147 tal transfer of miR-199a-5p in exosomes from quiescent HSCs.

148 more, we demonstrate that the most primitive quiescent HSPCs are more resistant to spontaneous reacti

149 ency than more differentiated HSPCs and that quiescent HSPCs are resistant to reactivation by histone

150 We show that these quiescent HSPCs are susceptible to predominantly latent

151 FN) pathways, which enforced cell cycling in quiescent HSPCs, resulting in their apoptotic death.

152 inase activity to examine the role of ATR in quiescent human cells.

153 l growth factors (GFs) that together promote quiescent human hematopoietic stem cell (HSC) expansion

154 l growth factors (GFs) that together promote quiescent human hematopoietic stem cell (HSC) expansion

155 In mammals the pathway is quiescent in many organs.

156 Healthy blood neutrophils are functionally quiescent in the bloodstream, have a short lifespan, and

157 ne-third of the world population and remains quiescent in the human body for decades.

158 Sperm cells are quiescent in the male reproductive system due to Zn(2+)

159 ve ISCs marked with HopxCreER were primarily quiescent (in G0), with inactive Wnt signaling and robus

160 bly, SCs and axons in uninjured DRs remained quiescent, indicating that caErbB2 enhanced regeneration

161 I) in the presence of acyclovir results in a quiescent infection resembling latency in which viral ge

162 The relative risk of relapse of quiescent inflammatory bowel disease with psychological

163 Although quiescent intestinal stem cell (ISC) populations have be

164 istence and interaction of proliferating and quiescent intestinal stem cells have been debated since

165 kers and methods of isolation for active and quiescent ISC populations are described as well as the n

166 DNA-PK-deficient quiescent leukemia cells and BRCA/DNA-PK-deficient proli

167 In quiescent liver, PTEN causes pathological steatosis when

168 flammatory targets, and that GC treatment of quiescent macrophages globally directs GRIP1 toward GR b

169 Here, we identify a quiescent mammary epithelial cell population expressing

170 r dead cells and efficiently clear them in a quiescent manner.

171 but did not compromise naive, regulatory, or quiescent memory T-cell pools, and had a modest nonimmun

172 mined that senescent cholangiocytes promoted quiescent mesenchymal cell activation in a platelet-deri

173 The transition from a quiescent metabolic state (dry seed) to the active state

174 Seed-aging assays showed that quiescent mmdh1mmdh2 seeds lost viability more than 3 ti

175 tly localized in the cytosol, where it has a quiescent monomer conformation.

176 -199a-5p, which was principally expressed in quiescent mouse hepatic stellate cells (HSCs) and direct

177 9a-5p-containing exosomes were shuttled from quiescent mouse HSCs to activated mouse HSCs in which CC

178 uppressed by a miR-199a-5p mimic, whereas in quiescent mouse HSCs, the inhibited CCN2 3'-UTR activity

179 Skeletal muscles harbor quiescent muscle-specific stem cells (MuSCs) capable of

180 osed stretches of passive, i.e. electrically-quiescent, muscles, the instantaneous firing rates (IFRs

181 le and single-cell analyses demonstrate that quiescent MuSCs express high levels of Myogenic Differen

182 to their ability to self-renew and exist as quiescent neural progenitors (QNPs) before differentiati

183 ta define novel REST targets to maintain the quiescent neural stem cell state.

184 -long generation of hippocampal neurons from quiescent neural stem cells (NSCs).

185 rsomedial nucleus, and Arc of reproductively quiescent NMRs.

186 arent reversal of their activated state to a quiescent, nonproliferative state.

187 iectasia mutated (ATM)-dependent and promote quiescent NSC (qNSC) activation, which does not occur in

188 ay activity discriminates quiescent from non-quiescent NSCs in the Drosophila nervous system.

189 The quiescent, nucleotide-free state in the P-glycoprotein t

190 s in alligator dental laminae, which contain quiescent odontogenic progenitors.

191 Following injury, quiescent olfactory stem cells rapidly shift to activate

192 low firing frequency network state (L) and a quiescent one (Q).

193 reatic stellate cells (PSCs) are regarded as quiescent, only to become activated in chronic pancreati

194 Establishment of a quiescent or latent infection in PNS neurons is a hallma

195 re endowed with high levels of 5hmC, whereas quiescent or proliferative neural progenitors show low t

196 ent responsible for maintaining homeostasis, quiescent or slowly proliferating stem/progenitor cells

197 local signals to determine whether to remain quiescent or undergo morphogenesis.

198 lk1) labels a rare population of long-lived, quiescent pancreatic cells.

199 these observations indicate that Dclk1 marks quiescent pancreatic progenitors that are candidates for

200 known malaria drug targets are expressed in quiescent parasites, but pathways involved in microbial

201 cle and charge compensation in the negative, quiescent part of the AC cycle.

202 mbus formation is suppressed and maintains a quiescent, patent vasculature.

203 measures using EMGs, which are performed on quiescent patients, we monitored activity during treadmi

204 Far from being passive and quiescent, pericytes and resident fibroblasts are busily

205 nstantly expressed throughout the hair cycle quiescent phase in outer bulge stem cells that produce t

206 acknowledgement." CONCLUSIONS: Even during a quiescent phase of the disease, unilateral and relapsing

207 r pain" and "acknowledgement." Even during a quiescent phase of the disease, unilateral and relapsing

208 The prolonged quiescent phase of the pyl8-1pyl9 double mutant was reve

209 phase infection and decreasing during a more quiescent phase, but generally remaining elevated at all

210 n change when KSHV switches from its latent (quiescent) phase to the lytic, infectious state.

211 nate 'active' phases of copious rainfall and quiescent phases of 'break'.

212 e extreme rainfall events, especially in the quiescent phases.

213 ely, blocking MyoD translation maintains the quiescent phenotype.

214 In LNs, CMV-specific T cells exhibited quiescent phenotypes independent of virus.

215 cores, and find that stress fluctuations in quiescent polycrystals are uniformly distributed rather

216 r of the epithelium; and a slowly cycling or quiescent pool that functions as reserve ISCs.

217 too rare to explain the vast majority of the quiescent population.

218 The signalling pathways operational in quiescent, post-development vasculature remain enigmatic

219 ion or was induced later during adulthood in quiescent preexisting oligodendrocytes, after active mye

220 The ovarian reserve represents the stock of quiescent primordial follicles in the ovary which is gra

221 ormone (AMH) induced a greater proportion of quiescent primordial follicles than control ExECs, indic

222 and can act by promoting the switch between quiescent/proliferating/differentiating myoblasts and by

223 Quiescent proviral genomes that persist during human imm

224 The induction of quiescent provirus is the goal of a new class of potenti

225 ues and can include both rapidly cycling and quiescent (q)SC populations.

226 However, the in vivo roles of HIFs in quiescent satellite cells and activated satellite cells

227 tivation dedifferentiates myocytes into Pax7 quiescent satellite cells, leading to severe defects in

228 Deletion of Pten in quiescent SCs leads to their spontaneous activation and

229 f Pten (phosphatase and tensin homologue) in quiescent SCs.

230 Deleting Foxc1 in activated, but not quiescent, SCs causes failure of the cells to reestablis

231 Germination, the process whereby a dry, quiescent seed springs to life, has been a focus of plan

232 Stem cell fate decisions to remain quiescent, self-renew or differentiate are largely gover

233 ntify choriocapillaris lesions in active and quiescent serpiginous choroiditis (SC) using swept-sourc

234 -OCTA prototype was used to image active and quiescent serpiginous lesions longitudinally before and

235 ts, we demonstrate conditional activation of quiescent sgRNAs programmed to respond to genetically en

236 d with subfractions displaying primitive and quiescent signatures.

237 fy a distinct subset of human T cells with a quiescent/slow-cycling phenotype, propensity for tissue

238 ell marker genes, revealing the existence of quiescent, slowly- and active-cycling ISC populations.

239 n the conventional positive feedback mode in quiescent solution show that hydrodynamic SECM offers at

240 when parasites developed into metabolically quiescent stage V gametocytes.

241 ofile of several proteins when entering this quiescent stage.

242 driving parasite differentiation to and from quiescent stages.

243 etal muscle, the adult stem cells maintain a quiescent state and proliferate upon injury.

244 ctivated Tie2 maintains the endothelium in a quiescent state characterized by dynamic barrier functio

245 and human CRC, we found that SPDEF induces a quiescent state in CRC cells by disrupting binding of be

246 tive to stress, whereas qSCs exit from their quiescent state in response to homeostatic imbalance and

247 HIV persists in a quiescent state in resting CD4+ T cells, where the repli

248 HSPCs exist in a quiescent state in vivo, and quiescence is correlated wi

249 rmore, our findings show that Msi2 maintains quiescent state of HFSCs in the process of the telogen-t

250 is required to establish and/or maintain the quiescent state of the egg cell in the absence of fertil

251 tic fibrosis through their activation from a quiescent state partially in response to profibrotic gro

252 oenvironment that facilitate adaptation to a quiescent state remains poorly understood.

253 upon maturation, the egg cell establishes a quiescent state that is maintained until fertilization.

254 s on the return of stem cells to a transient quiescent state through the rapid degradation of a key p

255 any tissues sustain themselves by entering a quiescent state to avoid genomic insults and to prevent

256 B cells predominate in a quiescent state until an antigen is encountered, which r

257 Super-numeral SCs attain a 'normal' quiescent state, accelerate regeneration, and maintain r

258 ation, reverted cells to a mitogen-sensitive quiescent state, from which they can later re-enter the

259 the wild type keeps most mutant clones in a quiescent state, strong selection pressures that kill th

260 ypical characterizations of cancer cell in a quiescent state, such as growth inhibition, apoptosis, G

261 In this quiescent state, the viral genome persists as a circular

262 beta -catenin, expression of SPDEF induced a quiescent state, which was reversed when SPDEF expressio

263 onsistent with homeostatic regulation of the quiescent state.

264 as a delayed response to stimulation in the quiescent state.

265 hemotherapy because it prevents entry into a quiescent state.

266 population exit to a transient or persistent quiescent state.

267 ect translational repression to maintain the quiescent state.

268 s restoration of inflamed endothelium into a quiescent state.

269 old is only attained when the beads are in a quiescent state.

270 cle stem cells (MuSCs) in vitro in a potent, quiescent state.

271 s from exiting the cell cycle and entering a quiescent state.

272 as they transition from a proliferating to a quiescent state.

273 r hypothermic conditions are maintained in a quiescent state.

274 cell's decision to enter a growth state or a quiescent state.

275 l growth through mediating cell entry into a quiescent state.

276 tency in human primary cells maintained in a quiescent state.IMPORTANCE Human immunodeficiency virus

277 the conventionally reported synchronized and quiescent states through an unusual sharp jump transitio

278 In growing hair follicles (HF), quiescent stem cells (SC) are maintained in the bulge re

279 intensity in neuroblast cells as compared to quiescent stem cells and mature granule neurons.

280 ngrams, inhibitory engrams can make memories quiescent, stored in a latent form that is available for

281 and calcineurin regulate cell cycle entry of quiescent T cells by controlling glycolysis and oxidativ

282 olecular circuits by which antigens activate quiescent T cells remain poorly understood.

283 (CAR-Ts) and second, re-animating endogenous quiescent T cells through checkpoint blockade.

284 While quiescent T cells use oxidative phosphorylation (OXPHOS)

285 Uterine smooth muscle cells remain quiescent throughout most of gestation, only generating

286 predictably switch isolated PSM cells from a quiescent to an oscillatory state in vitro, a behavior r

287 on of anemia resulted in mobilization of the quiescent to the active cluster and of the early to late

288 We find that quiescent TPCs resist DNA damage and exhibit increased t

289 gger a wound-healing response that mobilizes quiescent tumor stem cells into active proliferation.

290 VCAM-1 expression and leukocyte adhesion in quiescent tumour endothelial cells with intact insulin r

291 is was increased compared with patients with quiescent ulcerative colitis and that colitis was attenu

292 ematopoietic stem cells (HSCs) remain mostly quiescent under steady-state conditions but switch to a

293 ion in most animals, plant stem cells remain quiescent until the postembryonic phase of development.

294 which we find to be higher in spontaneously quiescent versus proliferating cells.

295 At least some of the quiescent viral genomes retain the capacity to reactivat

296 Prophages are quiescent viruses located in the chromosomes of bacteria

297 d importantly no significant reactivation of quiescent viruses was noticed.

298 Stem cells were immobile and quiescent without injury whereas their activated progeni

299 roteasome dynamics between proliferating and quiescent yeast in response to cellular requirements for

300 d actively repress its translation to remain quiescent yet primed for activation.