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1 henyl as a preferred substitution on the N-3 quinazolinone.
2 developed for the synthesis of 2-substituted quinazolinones.
3 for the easy generation of new and bioactive quinazolinones.
4 e 2-(2'-hydroxyphenyl)-6-[(125)I]iodo-4-(3H)-quinazolinone ((125)IQ(2-OH)).
5 4'-dihydroxyphenyl)-6-[127I/125I]iodo-4-(3H)-quinazolinone (127IQ2-OH,4-OH (2)/125IQ2-OH,4-OH (7)) wa
6 pine (2b) were modified to produce tricyclic quinazolinone 15-18 or benzothiadiazine 26-27 derivative
7      5,7-Dihydroxy-3-(4-hydroxyphenyl)-4(3H)-quinazolinone (1aa) acts as an agonist on both ER subtyp
8 se efforts led directly to identification of quinazolinone 28 that displays high selectivity for PI4K
9 oted isomerization of iminobenzoxazine 33 to quinazolinone 34, an N-acyliminium ion cyclization that
10 olo[1,2-a]benzoxazinones 3 and pyrrolo[1,2-a]quinazolinones 4, respectively, in good overall yields.
11                                              Quinazolinones 8 and pyrido[3,4-d]pyrimidin-4-ones 9 as
12              The improved performance of the quinazolinones against the mutant enzyme is attributed t
13 MR spectroscopies show that deprotonation of quinazolinones and phenylacetylene in THF/pentane soluti
14 oad substrate scope is demonstrated for both quinazolinone as well as diaryliodonium triflates.
15 iscover four novel series of 53 compounds of quinazolinone based on the concept of molecular hybridiz
16        Quin-C1 is a prototype of substituted quinazolinones based on which further structural modific
17  a program to develop practical syntheses of quinazolinone-based nonnucleoside reverse transcriptase
18 ptimization of a potent, selective series of quinazolinone-based TRPA1 antagonists.
19 precursor for the synthesis of N-substituted quinazolinones by incorporation of a palladium-catalyzed
20 arylsulfonyl-piperazine and spiro-piperidine-quinazolinone classes were identified with up to approxi
21                        The high potential of quinazolinone containing natural products and their deri
22 ry of a novel antibacterial (2) with a 4(3H)-quinazolinone core.
23 gous to the earlier studies of the series of quinazolinone derivatives 3, we also found 3-isopropoxyp
24 eration of carbon-heteroatom bond leading to quinazolinone derivatives and aza-Michael adducts under
25 action-binding between a series of iodinated quinazolinone derivatives and human placental alkaline p
26                        We studied a class of quinazolinone derivatives of the lead structure FR20 for
27  In our laboratories, piperidine-substituted quinazolinone derivatives were identified as a new class
28 one scaffold were tolerated to provide novel quinazolinone derivatives.
29                             The Pd-catalyzed quinazolinone-directed regioselective monoarylation of a
30 enyl-3, 4-dihydro-4-(trifluoromethyl)-2-(1H)-quinazolinones DPC 082 and DPC 083 and the 4-alkynyl-3,
31 ynyl-3, 4-dihydro-4-(trifluoromethyl)-2-(1H)-quinazolinones DPC 961 and DPC 963 were found to exhibit
32        A novel copper-catalyzed synthesis of quinazolinones from easily available 2-arylindoles and a
33 rnishes a series of substituted indolo[1,2-a]quinazolinones from the suitably fabricated indoles via
34 ficant molecules, such as benzoxazinones and quinazolinones, from simple anilides without installing
35 al products containing benzodiazepinone- and quinazolinone-fused ring systems can be assembled by non
36                                     This new quinazolinone has potent activity against methicillin-re
37 the 1,2-addition of PhCCLi to an O-protected quinazolinone implicates reaction via trisolvated PhCCLi
38 s has been developed, which provided various quinazolinones in up to 99% yields for 43 examples.
39 ium 2-(2'-phosphoryloxyphenyl)-6-iodo-4-(3H)-quinazolinone (IQ(2-P)) was docked in silico into the X-
40 -(2',4'-diphosphoryloxyphenyl)-6-iodo-4-(3H)-quinazolinone (IQ2-P,4-P), having the most favorable cal
41 philes to chiral auxiliary substituted 2(3H)-quinazolinones is described.
42 d-phase synthesis of 2-arylamino-substituted quinazolinones is described.
43 llowed by chemical synthesis of a library of quinazolinones, led to the discovery of (E)-3-(3-carboxy
44                             All of the novel quinazolinones of biological interest were synthesized b
45 ts, including benzophenones, acridinones and quinazolinones or quinazolines was identified and measur
46                Herein, we report a series of quinazolinone-pyrrolopyrrolones as potent and selective
47 on of methaqualone (2-methyl-3-o-tolyl-4(3H)-quinazolinone, Quaalude), an infamous sedative-hypnotic
48 ompound library and identified a substituted quinazolinone (Quin-C1, 4-butoxy-N-[2-(4-methoxy-phenyl)
49 piperidinyl)ethyl]-2,3-dihydro-2-thioxo-4(1H)quinazolinone (R59949), which blocks HIF-1alpha protein
50                                          The quinazolinone ring has been exploited as a directing gro
51 harmacophores, an arylurea moiety of 1 and a quinazolinone ring of 3, from two known series.
52                                              Quinazolinone rotational barriers about the chiral anili
53             Various functional groups on the quinazolinone scaffold were tolerated to provide novel q
54 n optimization effort was initiated around a quinazolinone screening hit 1 with promising cellular an
55 ges to the ethylene linker that connects the quinazolinone to the amide were also investigated but pr
56                     A small family of phenyl quinazolinone ureas is reported as potent modulators of
57 idation reaction for the facile synthesis of quinazolinone was developed.
58 ition of lithium phenylacetylide (PhCCLi) to quinazolinones was investigated using a combination of s
59 ynyl-3, 4-dihydro-4-(trifluoromethyl)-2-(1H)-quinazolinones were found to be potent non-nucleoside re
60 ically relevant 3-arylquinazolin-4(3H)-ones (quinazolinones) with high levels of enantioinduction ove

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