ライフサイエンスコーパス: rRNA promoter

1 associated with a well-characterized E. coli rRNA promoter.

2 res with utilization of the UP element of an rRNA promoter.

3 ween promoter recognition factor SL1 and the rRNA promoter.

4 productive transcriptional machinery on the rRNA promoter.

5 bited an increased ability to transcribe the rRNA promoter.

6 letely retained its ability to stimulate the rRNA promoter.

7 reduced transcriptional activity with a 19 S rRNA promoter.

8 icked, reduced, or enhanced DksA function on rRNA promoters.

9 effects of ppGpp on the negative control of rRNA promoters.

10 ed primarily at the level of initiation from rRNA promoters.

11 ters and the relationship between the tandem rRNA promoters.

12 ation of the Bacillus subtilis rrnB and rrnO rRNA promoters.

13 sponsible for the strength and regulation of rRNA promoters.

14 ed with a subset of promoters, including the rRNA promoters.

15 e synthesis rates and observing responses of rRNA promoters.

16 rs, but some are inhibited almost as much as rRNA promoters.

17 been observed to stabilize open complexes at rRNA promoters.

18 interactions that recruit RNA polymerase to rRNA promoters, accounting for their extraordinary stren

19 3'-diphosphate (ppGpp) concentrations and of rRNA promoter activities showed that rapid changes in th

20 al environment, are responsible for altering rRNA promoter activities under these feedback conditions

21 of Escherichia coli, display slightly lower rRNA promoter activity and much higher amino acid biosyn

22 , but in some growth transitions, changes in rRNA promoter activity are also dependent on relA, which

23 ogical parameter, as it affects not only the rRNA promoter activity but also the free-RNA polymerase

24 situation for E. coli where ppGpp decreases rRNA promoter activity by directly inhibiting RNA polyme

25 paper, we show that ppGpp directly inhibits rRNA promoter activity in vitro by decreasing the lifeti

26 of recombinant TBP to S2 extracts stimulated rRNA promoter activity in vitro.

27 e whether the increase in TBP was modulating rRNA promoter activity indirectly, by increasing activit

28 the available GTP pools, thereby modulating rRNA promoter activity indirectly.

29 NA promoter, whereas MBD1 and MBD3 inhibited rRNA promoter activity irrespective of the methylation s

30 of a negative-feedback control loop in which rRNA promoter activity responds to the amount of transla

31 h7 or S2 cells, a dose-dependent increase in rRNA promoter activity was observed.

32 NAP, reduces open complex lifetime, inhibits rRNA promoter activity, and amplifies effects of ppGpp a

33 hat is absolutely required for regulation of rRNA promoter activity.

34 eider S2 cell lines, X expression stimulated rRNA promoter activity.

35 of Ras mimicked the enhancing effect of X on rRNA promoter activity.

36 old decrease in open complex longevity at an rRNA promoter and a approximately 10-fold decrease in tr

37 , ribin, found in rodents, that binds to the rRNA promoter and stimulates its activity.

38 to RNA polymerase and potentiates control of rRNA promoters and certain amino acid promoters.

39 Given the kinetic similarities between rRNA promoters and the fis promoter (Pfis), we investiga

40 e analyzed the distal part of the ribosomal (RRNA) promoter and identified two sequence blocks which,

41 nhibit some Escherichia coli promoters (e.g. rRNA promoters) and to stimulate others (e.g. promoters

42 s of kcat and relative KM values for the two rRNA promoters, and relative values for free RNA polymer

43 ains a large number of rRNA operons, and its rRNA promoters are extremely strong.

44 In deltadksA mutants, rRNA promoters are unresponsive to changes in amino acid

45 Sequences present in rRNA promoters but absent from vsg ES promoters appear t

46 s that recruitment of large T antigen to the rRNA promoter by SL1 constitutes a crucial step in the a

47 he extraordinary transcriptional activity of rRNA promoters by increasing promoter escape, helping to

48 at direct control of r-protein promoters and rRNA promoters by the same signal, ppGpp/DksA, makes a m

49 Because rRNA promoters contain sequences within the discriminato

50 noptimal sigma1.2-discriminator interaction, rRNA promoters create the short-lived complex required f

51 Site-specific methylation of human rRNA promoter demonstrated that methylation of CpG at th

52 rRNA promoters in B. subtilis appear to be regulated by

53 sults suggest that vsg promoters and ectopic rRNA promoters in bloodstream-form T.brucei are restrain

54 ecular effectors responsible for controlling rRNA promoters in response to changes in the nutritional

55 dksA gene, deletion of greB had no effect on rRNA promoters in vivo.

56 CpG island located within the ribosomal RNA (rRNA) promoter in human hepatocellular carcinomas and pa

57 sults demonstrate that active synthesis from rRNA promoters is a major driving force for the distribu

58 ating NTP for transcription from B. subtilis rRNA promoters is GTP, promoter strength is determined p

59 sly as a determinant of proper regulation of rRNA promoters, is also required for the unusual TSS.

60 A genes, we constructed pHrD-IRES-Luc (human rRNA promoter-luciferase reporter).

61 We show here that rRNA promoter-mediated transcription is significantly (1

62 Selection of rRNA promoter mutants forming long-lived complexes, kine

63 ent downstream promoter but not the upstream rRNA promoter on the same plasmid.

64 was weaker than that of DksA, GreA affected rRNA promoters only modestly in vitro and, even when ove

65 well above the 0.8 mM needed to saturate the rRNA promoter P1 in vitro.

66 The in vivo expression levels of four rRNA promoter pairs (rrnp(1)p(2)) of Bacillus subtilis w

67 At the iNTPs-sensitive rRNA promoters ppGpp and DksA display an independent inh

68 rDNA contains a single-base deletion in the rRNA promoter region, in a phylogenetically conserved se

69 was identified in the Chlamydia trachomatis rRNA promoter region.

70 ng growth rate; for saturation the P1 and P2 rRNA promoters require a high RNA polymerase concentrati

71 and in vitro from the growth-rate-dependent rRNA promoter rrnB P1 and from the inversely growth-rate

72 wn that the activity of the Escherichia coli rRNA promoter rrnB P1 in vitro depends on the concentrat

73 y a small number of promoters, including the rRNA promoter rrnB P1, where the sequence has a very lar

74 on factor Fis activates the Escherichia coli rRNA promoters rrnB P1 and rrnE P1 by binding to sites c

75 sg ES promoters appear to be responsible for rRNA promoter-specific derepression in procyclic cells.

76 ntaining transcription factor that binds the rRNA promoter to form the committed complex.

77 the omega subunit of RNAP in the response of rRNA promoters to ppGpp.

78 in the dissociation direction, thus allowing rRNA promoters to respond to changes in the concentratio

79 d the discriminator region in an unregulated rRNA promoter variant and in the lambdaP(R) promoter.

80 ficant hypomethylation of methyl-CpGs in the rRNA promoter was observed in the tumor samples compared

81 Transcription from both ES and rRNA promoters was also efficiently repressed at a non-t

82 vsg is not normally expressed, all inserted rRNA promoters were derepressed but ES promoters remaine

83 se activity specifically from the methylated rRNA promoter, whereas MBD1 and MBD3 inhibited rRNA prom

84 Ras blocked the X-mediated induction of the rRNA promoters, whereas expression of a constitutively a

85 ation of MBD2 with the endogenous methylated rRNA promoter, which suggests a selective role for MBD2