ライフサイエンスコーパス: rabies virus

1 d to identify potent small molecules against rabies virus.

2 Mononegavirales, including measles virus and rabies virus.

3 cell-type-specific promoters, and a modified rabies virus.

4 iral infection involving an agent other than rabies virus.

5 ed each area's monosynaptic inputs using the rabies virus.

6 ear, and hence avoid an epizootic fadeout of rabies virus.

7 of Cre-dependent helper virus and a modified rabies virus.

8 etrograde spread of a genetically modifiable rabies virus.

9 city, is an important restriction factor for rabies virus.

10 lary ventrolateral column were infected with rabies virus.

11 als were given an intramuscular challenge of rabies virus.

12 e exposed, through aerosol, to 3 variants of rabies virus.

13 ted mice against a subsequent challenge with rabies virus.

14 dangerous zoonotic pathogens, like Ebola or rabies virus.

15 , such as HSV, Zika virus, dengue virus, and rabies virus.

16 the behavioural changes in hosts infected by rabies virus.

17 ho would otherwise succumb to infection with rabies virus.

18 with high homology (89 to 93%) to clade I of rabies viruses.

19 rences between vaccine strains and wild-type rabies viruses.

20 re less susceptible to lethal infection with rabies viruses.

21 rents were identified in rhesus monkeys with rabies virus, a retrograde transneuronal tracer.

22 nd to be an important restriction factor for rabies virus, acting directly or indirectly against vira

23 Genetic typing of rabies viruses allowed us to distinguish trends of disea

24 mples; 2) showing how cross species jumps of rabies virus among bat populations can be readily identi

25 against heterologous CDV strains.IMPORTANCE Rabies virus and canine distemper virus (CDV) cause high

26 hysiological recording system, combined with rabies virus and optogenetic cell-type identification, t

27 All bats survived exposure to aerosolized rabies virus and produced rabies neutralizing antibody.

28 cles of two recombinant rhabdoviral vectors, rabies virus and vesicular stomatitis virus (VSV), expre

29 including Ebola, Marburg, Nipah, Hendra, and rabies viruses and severe acute respiratory syndrome-cor

30 , lymphocytic choriomeningitis virus (LCMV), rabies virus, and Lassa virus.

31 ral encephalitis, including West Nile virus, rabies virus, and lymphocytic choriomeningitis virus, we

32 s, including Ebola virus, Lassa virus, LCMV, rabies virus, and Marburg virus, which was substituted f

33 accinated subjects developed protective anti-rabies virus antibody titers.

34 Rabies virus antigen was detected in archived autopsy br

35 s, rabies virus neutralizing antibodies, and rabies virus antigens were conducted on available specim

36 n gene do not suffice to render a pathogenic rabies virus apathogenic and are not a viable and safe a

37 continued the investigation into aerosolized rabies virus as a potential route of transmission.

38 We therefore applied a genetically modified rabies virus as a retrograde tracer to fill the dendrite

39 Here we use rabies virus as a retrograde transsynaptic tracer to stu

40 Here we use rabies virus as a retrograde transynaptic tracer to show

41 ffective at neutralizing the activity of the rabies virus as the mammalian-derived antibody (mAbM) or

42 Finally, using rabies-virus-assisted monosynaptic tracing, we show that

43 Over the last decade, rabies viruses associated with the silver-haired bat (SH

44 nlethal infections, is necessary to maintain rabies virus at levels consistent with field observation

45 e the mouse IFN-gamma gene into a pathogenic rabies virus backbone, SPBN, to produce the recombinant

46 These rabies virus-based approaches permit the linking of conn

47 LORAB1, a recombinant, bivalent, inactivated rabies virus-based EBOV vaccine, in rhesus and cynomolgu

48 use primary visual cortex (V1) with modified rabies virus-based input mapping, we have determined the

49 Here we use a recombinant rabies virus-based method to label a specific type of lo

50 Rabies virus-based monosynaptic tracing has been used to

51 Rabies virus-based retrograde tracing has developed into

52 sults demonstrate an important limitation of rabies virus-based retrograde tracing of sensory neurons

53 Using a monosynaptic rabies virus-based tracing technique, we studied the evo

54 Using a modified monosynaptic rabies virus-based transsynaptic tracing strategy, we sy

55 t rabies virus, illustrating that a bivalent rabies virus-based vaccine against CDV induces protectiv

56 Rabies virus-based vectors have been proven to be effici

57 Using a monosynaptic rabies viruses-based transneuronal tracing method combin

58 Rabies-virus-based input mapping indicated that LC-NE ne

59 ht help to protect wild dog populations from rabies virus, but not from canine distemper virus.

60 hrlichia canis, Neospora caninum and perhaps rabies virus, but not with exposure to canine distemper

61 eins of the Ebola, vesicular stomatitis, and rabies viruses by Nedd4 family HECT domain E3 ligases is

62 Here we show that deletion-mutant rabies virus can be specifically targeted to cells local

63 In this study, we demonstrate that rabies virus can infect sensory neurons in the somatosen

64 Recombinant rabies viruses can encode genes of interest for labeling

65 r stomatitis virus (VSV), like its relative, rabies virus, can cause neuropathy in mice if it enters

66 hereas all animals that received recombinant rabies viruses carrying only the CDV attachment protein

67 ts immunized twice with a mix of recombinant rabies viruses carrying the CDV fusion and attachment gl

68 RNA viruses, a group that includes Ebola and rabies viruses, catalyze RNA-dependent RNA polymerizatio

69 such as vesicular stomatitis virus (VSV) and rabies virus, catalyzes the transfer of 5'-phospho-RNA (

70 The rabies virus causes a fatal encephalitis and can be tran

71 (within host) for the immune responses to a rabies virus challenge, an immunotypic disease model tha

72 e exception of CD8 T cells, the effectors of rabies virus clearance are more commonly targeted to the

73 the Evelyn-Rokitnicki-Abelseth strain of the rabies virus confers retrograde axonal transport on thes

74 nstrate that the clearance of the attenuated rabies virus CVS-F3 from the CNS is an exception; increa

75 ) but not during clearance of the attenuated rabies virus CVS-F3 from the CNS tissues.

76 Here we combine rabies-virus-dependent retrograde mono-trans-synaptic la

77 s backbone, SPBN, to produce the recombinant rabies virus designated SPBNgamma.

78 DFA) detection remains the gold standard for rabies virus diagnostics.

79 ween ecological and evolutionary dynamics in rabies virus during its epidemic expansion into eastern

80 transfection of neurons with deletion-mutant rabies virus encoding channelrhodopsin-2, and used this

81 We have constructed a deletion-mutant rabies virus encoding EGFP and find it to be an excellen

82 and the membrane proteins thought to mediate rabies virus endocytosis (neural cell adhesion molecule,

83 r spinal cord, which are the known sites for rabies virus entry into the CNS, and enhancements in bra

84 copy, we demonstrated that pseudotyping with rabies virus envelope glycoprotein (RV-G) enabled the ax

85 Rabies virus exhibits a small genome that encodes a limi

86 These new rabies viruses express useful neuroscience tools, includ

87 retrogradely labeled following injections of rabies virus expressing enhanced green fluorescent prote

88 Monosynaptically restricted rabies virus facilitates the anatomical investigation of

89 Rabies virus found worldwide and prevalent throughout th

90 This report documenting the transmission of rabies virus from an organ donor to multiple recipients

91 e used retrograde transneuronal transport of rabies virus from single muscles of macaques.

92 e used retrograde transneuronal transport of rabies virus from single muscles of rhesus monkeys to id

93 ng the transneuronal retrograde transport of rabies virus from the diaphragm with the immunohistochem

94 by the retrograde transneuronal transport of rabies virus from the diaphragm, were immunopositive for

95 e used retrograde transneuronal transport of rabies virus from the rat kidney to identify the areas o

96 protein (N), and phosphoprotein (P) genes of rabies viruses from 2 human cases of encephalitic rabies

97 rabies viral vectors, recovery of G-deleted rabies viruses from cDNA, amplification of the viruses,

98 Incorporation of IFN-gamma into the rabies virus genome highly attenuated the virus.

99 ding to the first 19 nucleotides (nt) of the rabies virus genome, we demonstrate that L alone initiat

100 Using sequences encoding 78% of the rabies virus genome, we explored the extent, repeatabili

101 hnology that distinguishes between classical rabies virus (genotype 1) and European bat lyssaviruses

102 f a prophylactic mRNA-based vaccine encoding rabies virus glycoprotein (CV7201).

103 Seroconversion against rabies virus glycoprotein (G) and SHIV(89.6P) Env was de

104 himpanzee serotype 68 (AdC68) expressing the rabies virus glycoprotein (rab.gp) were tested for induc

105 (VSV) to encode a fluorophore and either the rabies virus glycoprotein (RABV-G) or its own glycoprote

106 re we show that a short peptide derived from rabies virus glycoprotein (RVG) enables the transvascula

107 etylcholine receptor (AchR)-binding peptide [rabies virus glycoprotein (RVG)-9R] effectively suppress

108 ibution studies, nanoparticles modified with rabies virus glycoprotein (RVG29) were loaded with small

109 -HIV; n = 20), control vector containing the rabies virus glycoprotein G gene (n = 10), or saline pla

110 lly in an anterograde direction, whereas the rabies virus glycoprotein gave a specifically retrograde

111 The neurotoxin-like region of the rabies virus glycoprotein inhibited acetylcholine respon

112 Furthermore, as this p137 RNA is fused to a rabies virus glycoprotein peptide that facilitates deliv

113 inding of this study is that a region in the rabies virus glycoprotein, with homologies to snake toxi

114 te at a molecular level its interaction with rabies virus glycoprotein.

115 vitro, as did full length ectodomain of the rabies virus glycoprotein.

116 Naturally occurring herpes and rabies viruses have been used for transneuronal circuit

117 Although modified rabies viruses have emerged as a powerful tool for traci

118 ew, most notably the alpha herpesviruses and rabies virus, have evolved to enter the NS efficiently a

119 ic transgenic complementation of recombinant rabies virus holds great promise for obtaining cellular-

120 respective roles of ecology and evolution in Rabies virus host shifts.

121 rus infection were attributed to aerosolized rabies virus; however, little work has been done to addr

122 animals developed protective titers against rabies virus, illustrating that a bivalent rabies virus-

123 haracterized, was demonstrated to neutralize rabies virus in a fluorescent antibody virus neutralizat

124 Using pseudotyped rabies virus in a transgenic Gpr151-Cre mouse line, mono

125 s HRIG for post-exposure prophylaxis against rabies virus in hamsters, indicating that differences in

126 abies virus (RABV) has been used as a street rabies virus in laboratory investigations.

127 stence mechanisms of vampire-bat-transmitted rabies virus in Latin America, we use data from a spatia

128 Using transneuronal transport of rabies virus in macaques, we found that a disynaptic pat

129 ere validated by efficacy against infectious rabies virus in mammalian cell culture.

130 fluorescence antibody staining demonstrated rabies virus in multiple tissues from all recipients.

131 erized vaccine-induced cellular responses to rabies virus in naive adult volunteers.

132 a set of gene sequences from an epidemic of rabies virus in North American raccoons.

133 sceptible to infection with EnvA-pseudotyped rabies virus in tumor virus A receptor transgenic mice,

134 fter restimulation of PBMCs with inactivated rabies virus in vaccinated, but not in unvaccinated, ind

135 fashion, aspects of the complex evolution of rabies viruses in different host-reservoir species.

136 in the raphe nuclei were also infected with rabies virus, indicating that midline cells utilizing mu

137 Rabies virus induces drastic behaviour modifications in

138 The rabies viruses infecting the donor and the deceased kidn

139 essing cells, allowing us to control initial rabies virus infection and subsequent monosynaptic retro

140 rs across the BBB is critical to surviving a rabies virus infection and that HPA axis activity may in

141 es involved in innate immune response during rabies virus infection and that the M protein of wild is

142 Using rabies virus infection as an example, we discuss the adv

143 Between 1956 and 1977, 4 human cases of rabies virus infection were attributed to aerosolized ra

144 sing vaccine for prevention and treatment of rabies virus infection.

145 IV5-G protected mice as late as 6 days after rabies virus infection.

146 tein (G) of rabies (PIV5-G) as a therapy for rabies virus infection: we have found that PIV5-G protec

147 ABV is associated with the majority of human rabies virus infections in the United States and Canada.

148 We report here on experiments that use rabies virus injections into V4 to retrogradely label mo

149 We injected rabies virus into lobules VB-VIIIB of the vermis and use

150 his relay directly, we injected transynaptic rabies virus into several extrastriate visual areas.

151 Glycoprotein-deleted (DeltaG) rabies virus is a powerful tool for studies of neural ci

152 n and that the M protein of wild isolates of rabies virus is a viral immune-modulatory factor playing

153 Based on rabies virus, it is genetically targetable, allows high-

154 rapid production of murine IFN-gamma by the rabies virus itself would induce a more robust antiviral

155 Rabies virus, lenti- and retroviruses, and herpesviruses

156 Vampire bat rabies virus lineages associated with antigenic variant

157 iciently long incubation periods, allows for rabies virus maintenance.

158 e order Mononegavirales, which also includes rabies virus, measles virus, and respiratory syncytial v

159 virus (VSV) and related rhabdoviruses (e.g., rabies virus) mediate both cell attachment and membrane

160 Using rabies virus -mediated monosynaptic retrograde tracing t

161 Glycoprotein-deleted rabies virus-mediated monosynaptic tracing has become a

162 rategy combining retroviral birthdating with rabies virus-mediated putative retrograde trans-synaptic

163 Here we combine rabies virus-mediated retrograde tracing with retroviral

164 The virus is now termed dog rabies virus-Mexico (DRV-Mexico).

165 Using rabies virus monosynaptic tracing, we mapped cocaine-ind

166 ary analyses indicate multiple barriers that Rabies virus must overcome through adaptation.

167 Rabies viruses, negative-strand RNA viruses, infect neur

168 etermine the lowest dose of CV7201 to elicit rabies virus neutralising titres equal to or greater tha

169 organ recipients remained asymptomatic, with rabies virus neutralizing antibodies detected in their s

170 ct rabies virus-specific binding antibodies, rabies virus neutralizing antibodies, and rabies virus a

171 ce immunized with LBNSE-CXCL13 produced more rabies virus-neutralizing antibodies (VNAs) and develope

172 us in colonies and much higher prevalence of rabies virus-neutralizing antibodies.

173 Serum rabies virus-neutralizing antibody titers sufficed to pr

174 NA recombinant technology to express 3 human rabies virus-neutralizing human monoclonal antibodies (h

175 V is a negative strand RNA virus, similar to rabies virus or Ebola virus, that has a unique mechanism

176 s of a 30-yr data set covering a large-scale rabies virus outbreak among North American raccoons reve

177 Here we show that inactivated rabies virus particles containing the MERS-CoV S1 protei

178 ndidates based on recombinant vaccine strain rabies virus particles, which concurrently display the p

179 jor unanswered research questions related to rabies virus pathogenesis, especially those connecting t

180 Despite its ability to infect all mammals, Rabies virus persists in numerous species-specific cycle

181 Understanding the interactions between rabies virus (RABV) and individual host cell proteins is

182 oviral vaccine vector platforms, recombinant rabies virus (RABV) and recombinant vesicular stomatitis

183 both survival from infection with attenuated rabies virus (RABV) and reduction of neurological sequel

184 rly chemokines, is an important mechanism of rabies virus (RABV) attenuation.

185 Both canine distemper virus (CDV) and rabies virus (RABV) cause lethal disease in wild and dom

186 Rabies virus (RABV) causes rabies disease resulting in >

187 la virus (EBOV) vaccine based on inactivated rabies virus (RABV) containing EBOV glycoprotein (GP) in

188 Our studies demonstrate that wild-type (wt) rabies virus (RABV) does not activate DCs.

189 letion variant of the SAD-B19 vaccine strain rabies virus (RABV) has been the reagent of choice in mo

190 A canine rabies virus (RABV) has been used as a street rabies vir

191 Untreated rabies virus (RABV) infection leads to death.

192 sible for vaccine-induced protection against rabies virus (RABV) infections in postexposure settings.

193 Rabies virus (RABV) maintenance in bats is not well unde

194 Rabies virus (RABV) P gene mRNA encodes five in-frame st

195 asome recognizes RNA viruses and its role in rabies virus (RABV) pathogenicity and immunogenicity rem

196 MIP-1alpha in mouse brain further decreased rabies virus (RABV) pathogenicity.

197 Rabies virus (RabV) phospho (P) protein, which is largel

198 The rabies virus (RABV) phosphoprotein P is a multifunctiona

199 Rabies virus (RABV) postexposure prophylaxis (PEP) requi

200 dress this need, we developed an inactivated rabies virus (RABV) that contains the MERS-CoV spike (S)

201 In this study, a recombinant rabies virus (RABV) that expressed murine interleukin-7

202 l infections, we investigated the ability of rabies virus (RABV) to activate DCs.

203 -deficient, and (iii) chemically inactivated rabies virus (RABV) vaccines expressing Zaire Ebola viru

204 the live but not UV-inactivated recombinant rabies virus (RABV) variant TriGAS in mice induces the r

205 ptive chimpanzees to test oral delivery of a rabies virus (RABV) vectored vaccine against Ebola virus

206 Its pathogen, rabies virus (RABV), can utilize its viral proteins, suc

207 Replication-deficient rabies virus (RABV)-based vaccines induce rapid and pote

208 cing the protective immune responses against rabies virus (RABV).

209 r the RNA-dependent RNA polymerase (RdRP) of rabies virus (RABV).

210 ted GL261 tumor-bearing mice with attenuated rabies virus (RABV).

211 proteins in the brains of mice infected with rabies virus (RABV).

212 Replication-deficient rabies viruses (RABV) are promising rabies postexposure

213 Attenuated rabies viruses (RABV) are unique tools to study CNS immu

214 ent study, it was found that the recombinant rabies viruses rB2c-K1685A and rB2c-K1829A, carrying mut

215 type 1) and PPPY-containing viruses (VSV and rabies virus) regarding their dependence on specific hos

216 eurological disease caused by infection with rabies virus, registers throughout recorded history.

217 Rabies viruses related to Lasiurus cinereus, Histiotus m

218 distinctive antigenic patterns were found in rabies viruses related to rabies in vampire bats in Mexi

219 Recombinant rabies viruses rendered replication-deficient by the del

220 amma directly in the infected tissue reduces rabies virus replication and spread, limiting its pathog

221 tional significance of the components of the rabies virus replication machinery is incomplete.

222 In Latin America, vampire-bat-transmitted rabies virus represents a key example of how such uncert

223 ecific infection of MEC-LII with recombinant rabies virus results in unambiguous labeling of monosyna

224 Retrograde circuit mapping with modified rabies viruses revealed that the On-DSGCs project to the

225 olecular methods allow reliable detection of rabies-virus RNA in biological fluids or tissue before d

226 inserted into the genome of the recombinant rabies virus (rRABV) strain LBNSE, and the effect of the

227 To overcome these problems, we used rabies virus (RV) as a retrograde transneuronal tracer.

228 ermeability in mice, whether associated with rabies virus (RV) clearance or CNS autoimmunity, is unal

229 Rabies virus (RV) has recently been developed as a novel

230 Rabies virus (RV) induces encephalomyelitis in humans an

231 Rabies virus (RV) infection is a fatal nervous system di

232 f tumor necrosis factor alpha (TNF-alpha) on rabies virus (RV) infection of the mouse central nervous

233 We injected rabies virus (RV) into selected regions of the cerebella

234 While the glycoprotein (G) of rabies virus (RV) is known to play a predominant role in

235 Rabies virus (RV) nucleoprotein (N) tightly encapsidates

236 tudies indicate that the interaction between rabies virus (RV) phosphoprotein and the dynein light ch

237 A major goal in rabies virus (RV) research is to develop a single-dose p

238 TaqMan PCR-based method for the detection of rabies virus (RV) RNA in tissue samples.

239 ed tissue culture-adapted and natural street rabies virus (RV) strains differ greatly in their neuroi

240 Previous comparisons of different rabies virus (RV) strains suggested an inverse relations

241 The contribution of host factors to rabies virus (RV) transcription/replication and axonal/t

242 The nonpathogenic phenotype of the live rabies virus (RV) vaccine SPBNGAN is determined by an Ar

243 Recombinant rabies virus (RV) vaccine strain-based vectors have been

244 Rabies virus (RV) vaccine strain-based vectors show sign

245 Several rabies virus (RV) vaccine strains containing an aspartic

246 Although current postexposure prophylaxis rabies virus (RV) vaccines are effective, approximately

247 after a single immunization, live-attenuated rabies virus (RV) vaccines could be particularly useful

248 Rabies virus (RV), a member of the Rhabdoviridae family,

249 Viral vectors based on influenza virus, rabies virus (RV), and vaccinia virus (VV) were used to

250 ng with EnvB pseudotyped lentivirus (LV) and rabies virus (RV), to selectively coinfect ErbB4-express

251 Recombinant rabies virus (RV)-based vectors have demonstrated their

252 Postexposure treatment (PET) of wild-type rabies virus (RV)-infected mice with a live-attenuated t

253 vestigated after the mice were infected with rabies virus (RV).

254 tically from hindlimb extensor muscles using rabies virus (RV).

255 utralizes several fixed and street wild-type rabies viruses (RVs).

256 Using a data set of hundreds of rabies viruses sampled from 23 North American bat specie

257 Dengue virus, tick-borne encephalitis virus, rabies virus, severe acute respiratory syndrome coronavi

258 vidual viral lineages revealed that although rabies viruses shared consistent three-stage processes o

259 Silver-haired bat rabies virus (SHBRV) infection induces a strong virus-sp

260 ion, we developed a self-inactivating DeltaG-rabies virus (SiR) that transcriptionally disappears fro

261 Laboratory tests to detect rabies virus-specific binding antibodies, rabies virus n

262 erstand the molecular machinery required for rabies virus spread in the nervous system.

263 an infectious clone of the highly pathogenic rabies virus strain CVS-N2c and replaced its cognate gly

264 mice infected with an attenuated laboratory rabies virus strain.

265 The matrix (M) protein of wild isolates of rabies virus such as Tha (M-Tha) was previously shown to

266 s captured in Trinidad in the 1950s during a rabies virus surveillance program.

267 on in these circuits, we used a monosynaptic rabies virus system to generate brain-wide maps of neuro

268 We used the monosynaptic rabies virus system, in conjunction with mice expressing

269 omplish this, we used a genetically modified rabies virus that acts as a retrograde tracer and fills

270 Both vectors induced Abs to rabies virus that could be detected in serum and from mu

271 Both vectors induced antibodies to rabies virus that could be detected in serum and mucosal

272 Using a modified rabies virus that expresses green fluorescent protein, w

273 synaptic infection from the spinal cord with rabies viruses that carry glycoproteins in their envelop

274 Here we generated recombinant inactivated rabies viruses that carry one of the CDV glycoproteins o

275 Using paired cytopathic and noncytopathic rabies viruses that differ by only two amino acids, we i

276 We used a monosynaptic rabies virus to define the circuit's functional connecti

277 We also show that engineering a lethal rabies virus to express IFN-gamma directly in the infect

278 Here, we used transneuronal transport of rabies virus to identify the areas of the primate cerebr

279 a recently developed tracing system based on rabies virus to overcome all three constraints.

280 ice, recombinant adeno-associated virus, and rabies virus to produce sparse but binary labeling of se

281 nables trans-synaptic spreading of G-deleted rabies viruses to directly connected, presynaptic neuron

282 Using rabies virus tracing strategies Weissbourd et al. (2014)

283 Combining rabies-virus tracing, optical clearing (CLARITY), and wh

284 Unlike the 2 previous clusters of rabies virus transmission through solid organ transplant

285 icular stomatitis virus (VSV), a relative of rabies virus transmitted by insect bites, that SCS macro

286 Using a modified rabies virus transsynaptic tracing strategy, we labeled

287 y recipient were consistent with the raccoon rabies virus variant and were more than 99.9% identical

288 The fox rabies virus variant descended as an irregular wave with

289 Genetic analysis revealed a canine rabies virus variant found only in the patient's home co

290 aphic relationships among 83 isolates of fox rabies virus variant using nucleotide sequences from the

291 It has been postulated that different rabies virus variants associated with particular vectors

292 differences in rabies due to canine and bat rabies virus variants have been noted, but no detailed s

293 differences in the route of viral spread of rabies virus variants in the nervous system, although ce

294 erlying geographic expansions of vampire bat rabies virus (VBRV) in Peru.

295 the safety and immunogenicity of attenuated rabies virus vectors expressing simian-human immunodefic

296 er VLPs, as well as vesicular stomatitis and rabies viruses (VSV and RABV, respectively).

297 Using a genetically modified rabies virus, we demonstrated that molecular layer perfo

298 Antibodies against rabies virus were present in three of the four recipient

299 immunopositive neurons that were infected by rabies virus were significantly less prevalent in the po

300 Rabies viruses whose glycoprotein (G) gene is deleted fr