ライフサイエンスコーパス: radial glial cell

1 cell cycle coupling via Cyclin D in a single radial glial cell.

2 retinaldehyde dehydrogenase, is expressed by radial glial cells.

3 llary acidic protein (GFAP) in telencephalic radial glial cells.

4 ed with an abrupt termination of many of the radial glial cells.

5 ocytes by stimulating somal translocation of radial glial cells.

6 ut apparent surface-mediated guidance of the radial glial cells.

7 l phenotype, activates the erbB2 promoter in radial glial cells.

8 erts a critical role in the establishment of radial glial cells.

9 The radial glial cell, a transient embryonic cell type known

10 Thanks to the persistence of radial glial cells acting as neural stem cells, the brai

11 and that the basal fibre, inherited by outer radial glial cells after ventricular radial glial divisi

12 dial glia results in the self-renewal of the radial glial cell and the birth of a neuron.

13 oliferation and premature differentiation of radial glial cells and aberrant positioning of newborn n

14 of VZ intermediate progenitors derived from radial glial cells and are distinct from the multipolar

15 Radial glial cells and astrocytes function to support th

16 tion between the two major progenitor types, radial glial cells and basal progenitors, was impaired.

17 monstrated by inactivating the Fgfr1 gene in radial glial cells and by RNAi knockdown of Fgfr1 in viv

18 eactivity is detected simultaneously in both radial glial cells and cells that have the positional an

19 receptor, Cxcr4, is expressed in cerebellar radial glial cells and conditional Cxcr4 ablation with N

20 s of cortical neural progenitor cells (NPCs)-radial glial cells and intermediate progenitor cells-was

21 ity is detected in the transitional forms of radial glial cells and mature astrocytes, but not in neu

22 croscopy, we performed time-lapse imaging of radial glial cells and measured filopodial motility in t

23 sent study examined the relationship between radial glial cells and newborn neurons in the adult dent

24 ventricular radial glial cells produce outer radial glial cells and seed formation of the outer subve

25 ted that both cycling and noncycling Sox2(+) radial glial cells and Tbr2(+) intermediate progenitors

26 expression to the nestin(+)/Pax6(+)/GLAST(+) radial glial cells and Tbr2(+) intermediate progenitors

27 suggesting that defective connection between radial glial cells and the pial surface mediated by LAMB

28 diate interactions of migrating neurons with radial glial cells and to function as a receptor for the

29 cerebral cortex contains migrating neurons, radial glial cells, and a large population of cycling pr

30 We report that the radial glial cell antigen RC2 identifies the majority of

31 However, the mechanisms that determine how radial glial cells are established, maintained, and tran

32 provide evidence that mouse Fezf2-expressing radial glial cells are multipotent progenitors that sequ

33 Together these results demonstrate that radial glial cells are neural progenitors in the develop

34 al and precursor cells by demonstrating that radial glial cells are themselves neuronal progenitor ce

35 These results identify Fezf2(+) radial glial cells as a multipotent neocortical progenit

36 ry receptor AXL is highly expressed by human radial glial cells, astrocytes, endothelial cells, and m

37 lear migration (INM)--a hallmark of cortical radial glial cell development.

38 C is not essential for the role of MARCKS in radial glial cell development.

39 Surprisingly, Dcx(ko/Y) radial glial cells displayed spindle orientation abnorma

40 Once formed, polarized radial glial cells divide either symmetrically or asymme

41 a two-step process in which Pax6-expressing radial glial cells divide in the VZ to produce Tbr2-expr

42 Numb expression suppress mPar3 regulation of radial glial cell division and daughter cell fate specif

43 investigation of spindle orientation during radial glial cell division, revealed that NFIX promotes

44 How radial glial cells establish and maintain their morpholo

45 to reduced reelin signaling and disorganized radial glial cell fibers.

46 developing cerebral cortex, neurons regulate radial glial cell function and radial glial cells, in tu

47 Radial glial cells function during CNS development as ne

48 hin the first few days after labeling, these radial glial cells gave rise to neurons, oligodendrocyte

49 The mechanisms of human outer radial glial cell generation are unknown, but are propos

50 Radial glial cell generation is significantly impaired i

51 Radial glial cells in the cerebellum were intensely labe

52 Radial glial cells in the cerebral cortex serve as proge

53 f interactions between migrating neurons and radial glial cells in the developing cerebral cortex.

54 of the switch from neuroepithelial cells to radial glial cells in the developing mammalian cerebral

55 cells, and it causes cell-cycle deficits of radial glial cells in the embryonic mouse cortex and hum

56 tributed to protracted neurogenesis by outer radial glial cells in the outer subventricular zone, a r

57 te here that calcium waves propagate through radial glial cells in the proliferative cortical ventric

58 oon cells and dysplastic neurons derive from radial glial cells in the telencephalic ventricular zone

59 Neurons arise directly from radial glial cells in the ventricular zone (VZ) and indi

60 During early postnatal periods, radial glial cells in various ventricular zones of the b

61 rons regulate radial glial cell function and radial glial cells, in turn, support neuronal cell migra

62 To study how migrating neurons and radial glial cells influence each others' function in th

63 Further, differentiation of radial glial cells into astrocytes was accelerated, sugg

64 ptor complex, leads to the transformation of radial glial cells into astrocytes.

65 CYFIP1 and WAVE signaling similarly affects radial glial cells, leading to their ectopic localizatio

66 In the absence of APC, radial glial cells lose their polarity and responsivenes

67 We further find that outer radial glial cell mitotic behaviour is cell intrinsic, a

68 Radial glial cell modulation could thus affect neuron pr

69 proposed to involve division of ventricular radial glial cells; neural stem cells present in all dev

70 These results demonstrate that radial glial cells not only serve as progenitors for man

71 mitotic spindle orientation increased outer radial glial cell number, and ultimately neuronal number

72 Radial migration, apparently supported by radial glial cells, occurred within the proliferative zo

73 In addition to radial glial cells of neurohistogenesis, immature astroc

74 ) or double knock-out mice, respectively] in radial glial cells of the dorsal telencephalon.

75 ic carnivore, focusing our analysis on outer radial glial cells (oRGs).

76 Radial glial cells play a critical role in the construct

77 In the ventricular zone, the radial glial cell population remains largely unaltered m

78 pathway but becomes minimal or absent where radial glial cell processes enter the marginal zone regi

79 reas the protein is exclusively expressed in radial glial cell processes that occupy the rhombomere b

80 ructure formed between migrating neurons and radial glial cell processes.

81 Here we show that human ventricular radial glial cells produce outer radial glial cells and

82 larly, ZIKA-NS2A, but not DENV-NS2A, reduces radial glial cell proliferation and causes AJ deficits i

83 active in the cerebellar VZ and essential to radial glial cell proliferation and expansion of GABAerg

84 Dystroglycan also regulates perinatal radial glial cell proliferation and transition into inte

85 photoreceptor cells, associated neurons, and radial glial cells, rapamycin prevented nuclear and cell

86 nd adhesion interactions between neurons and radial glial cells regulate neuronal migration as well a

87 Recent work suggests that radial glial cells represent many, if not most, of the n

88 Embryonically, proliferation of radial glial cells (RGC) and intermediate precursors (IP

89 11.5 (E11.5), the majority of Pax6-positive radial glial cells (RGCs) and Tbr2-positive intermediate

90 There are indications that radial glial cells (RGCs) are involved in initiating mye

91 Radial glial cells (RGCs) are the most abundant macrogli

92 ne (VZ) challenges the widely held view that radial glial cells (RGCs) are the sole occupants of this

93 e generated in a temporal sequence, with all radial glial cells (RGCs) contributing to both lower and

94 mapping to demonstrate that Fezf2-expressing radial glial cells (RGCs) exist throughout cortical deve

95 evelopment of the mammalian cerebral cortex, radial glial cells (RGCs) generate layer-specific subtyp

96 ule precursors (CGPs) and differentiation of radial glial cells (RGCs) in the cerebellum.

97 Radial glial cells (RGCs) in the developing cerebral cor

98 Radial glial cells (RGCs) in the ventricular neuroepithe

99 During vertebrate cortical neurogenesis, radial glial cells (RGCs) serve as neural stem cells tha

100 t two types of dividing cells in the VZ: (1) radial glial cells (RGCs) that span the entire neocortic

101 e neocortical ventricular zone (VZ) contains radial glial cells (RGCs) with restricted fate potential

102 go transitions from neuroepithelial cells to radial glial cells (RGCs), and later, a subpopulation of

103 s seen to colabel subsets of Pax6-expressing radial glial cells (RGCs), whereas only cD2 colabeled wi

104 The polarity and adhesion of radial glial cells (RGCs), which function as progenitors

105 The polarity and organization of radial glial cells (RGCs), which serve as both stem cell

106 The radial glial cells serve as neural progenitors and as a

107 Because radial glial cells supply the brain with RA during the d

108 t antiadhesive signaling via SPARC-like 1 on radial glial cell surfaces may enable neurons to recogni

109 two types of macroglial cells, Muller cells, radial glial cells that are the principal macroglial cel

110 developing rodent cortex are generated from radial glial cells that function as neural stem cells.

111 During asymmetric divisions of radial glial cells, the basal cell may inherit the radia

112 sufficient to induce somal translocation of radial glial cells throughout the cortex; furthermore, t

113 iking: Zac1 delayed the transition of apical radial glial cells to basal intermediate neuronal progen

114 uring embryonic brain development arise from radial glial cells which communicate, in part, via ATP m

115 o promotes the maintenance and elongation of radial glial cells, which are essential for guiding neur

116 t in part by suppressing Notch activation in radial glial cells, which leads to the increased express

117 Radial glial cells within the scaffold constantly intera