ライフサイエンスコーパス: radioactivity

1 le in vivo and the lowest renal retention of radioactivity.

2 zation in vitro of the total cell-associated radioactivity.

3 0% +/- 4.6% to 85.6% +/- 11.7% of introduced radioactivity.

4 ting cocktails for measurements of low (14)C radioactivity.

5 the major clearance and excretion routes for radioactivity.

6 ten hindered by the presence of a high bowel radioactivity.

7 ously) resulted in a uniform distribution of radioactivity.

8 uminous supernovae, which are not powered by radioactivity.

9 th postmortem myocardial tissue well-counted radioactivity.

10 ochemical purity, and >90 GBq/mumol specific radioactivity.

11 uptake of the 2 tracers and clearance of the radioactivity.

12 brain and fetal liver distribution of (11)C-radioactivity.

13 27 min after injection in regions with high radioactivity.

14 oduced in high purity and with high specific radioactivity.

15 d the (3)H-labeled ligand with high specific radioactivity.

16 Fukushima lack international warnings about radioactivity.

17 the two-dimensional gel sections containing radioactivity.

18 Nuclisome particles with increasing specific radioactivity.

19 of crude or purified samples with or without radioactivity.

20 -time decay rates that are inconsistent with radioactivity.

21 MGMT activity are time-consuming and employ radioactivity.

22 Bone had low levels of radioactivity.

23 r ex vivo determination of tissue-associated radioactivity.

24 gh radiochemical yield, purity, and specific radioactivity.

25 environment in the context of this elevated radioactivity.

26 and biliary excretion (CLbile) clearances of radioactivity.

27 iation] [351.5 MBq +/- 125.8]; mean specific radioactivity, 1200 mCi/mmol +/- 714 [44.4 GBq/mmol +/-

28 Radioactivity accumulated in the skull throughout the en

29 ration of both probes resulted in high tumor radioactivity accumulation (16.5 +/- 2.8 and 8.6 +/- 1.3

30 ere with high radiation absorbed doses, high radioactivity accumulation by liver and kidney should be

31 The radioactivity accumulation in normal organs, except for

32 CO2 release amounted to 17.4% of the initial radioactivity after 63 days of incubation.

33 We found increased uptake of radioactivity after injection of (11)C-PBR28 ipsilateral

34 Uptake of radioactivity after injection of (11)C-PBR28 was measure

35 Measurements of external whole tissue radioactivity after intravenous injection of Tc-DTPA rep

36 layer chromatography to eliminate the use of radioactivity and allows MGMT activity to be rapidly mea

37 C) method performs a joint reconstruction of radioactivity and attenuation from the emission data to

38 The administered radioactivity and effective radiation doses absorbed wer

39 psy, all tissues were assessed for levels of radioactivity and evaluated for histologic abnormalities

40 ted non-SLNs, we assayed all lymph nodes for radioactivity and fluorescence intensity.

41 The advantages of electrochemistry over radioactivity and fluorescence make this assay an access

42 l blood was sampled for measurement of blood radioactivity and metabolite analysis.

43 a between 1953 and 1963 dispersed long-lived radioactivity and nuclear weapons debris including pluto

44 EWOD, starting with approximately 333 MBq of radioactivity and obtained up to 52 MBq (non-decay-corre

45 degradation of cardiac SPECT by extracardiac radioactivity and partial-volume effect.

46 itable radiochemical yield and high specific radioactivity and purity.

47 over 4 h with sampling of venous bloods for radioactivity and radioactive metabolite quantification.

48 le sediment-bound residue (40-60% of applied radioactivity) and smaller amounts of photoproducts.

49 Blood levels of radioactivity, antibodies, shed serum HER2, and toxicity

50 fter intravenous injection of (18)F-AZD4694, radioactivity appeared rapidly in brain.

51 activity declined over 2 h, of the remaining radioactivity, approximately 90% was due to parent (18)F

52 PET data, using metabolite-corrected plasma radioactivity as the input function.

53 determined by PET quantification and tissue radioactivity assay.

54 ions of previously reported spectroscopic or radioactivity assays and may, therefore, facilitate the

55 he only sites with prominent accumulation of radioactivity at 4 h after injection.

56 l lymph nodes retain greater than 95% of the radioactivity at both 1 and 36 h after injection.

57 nificantly, depending on the distribution of radioactivity at the cellular and multicellular levels.

58 evolutionary discoveries about radiation and radioactivity at the end of the century that ushered in

59 Radioactivity at the T cell injection sites and in the t

60 iotin allows rapid, specific localization of radioactivity at tumor sites, making it an optimal metho

61 Current PGT assays include radioactivity-based methods, which rely on liquid-liquid

62 h subgroups had rapid fractional declines in radioactivity between the peak and late values (P < 0.00

63 Our assay does not require radioactivity, but radioactively labeling the TFs enable

64 Treatment with AMD3465 inhibited uptake of radioactivity by the tumors in both models.

65 the self-dose received by a cell containing radioactivity can be more radiotoxic than the cross-dose

66 It has been found that radioactivity can hinder aggregation of particles becaus

67 Radioactivity can influence surface interactions, but it

68 (64)Cu-FBP8 administration to further assess radioactivity clearance.

69 Blood radioactivity cleared quickly, whereas myocardial uptake

70 ned higher concentrations of salts and total radioactivity compared to prefracturing fluids.

71 but ex vivo CLI was also correlated with the radioactivity concentration (r(2) = 0.35-0.94).

72 scans were also analyzed to determine tissue radioactivity concentration (TRC) from 3-dimensional reg

73 The plasma and tissue time-radioactivity concentration curves of (11)C were integra

74 Metabolite-corrected plasma radioactivity concentration fit a biexponential (half-li

75 xperiments, the mean accuracy in quantifying radioactivity concentration in absolute terms was within

76 correction allows quantification of (99m)Tc radioactivity concentration in absolute terms within 3.6

77 Current assessments of the radioactivity concentration in liquid wastes focus on a

78 The images showed that the radioactivity concentration in skeletal muscle was highe

79 The radioactivity concentration in the patients' urine serve

80 ptake for a single cell was measured using a radioactivity concentration of 37 MBq/mL during the radi

81 cular organs demonstrated a slow decrease in radioactivity concentration over time consistent with cl

82 c acid (3) showed excellent heart/background radioactivity concentration ratios along with highest re

83 The percentage change per minute in radioactivity concentration was calculated in high- and

84 Tumor detection and radioactivity concentration within the urinary bladder w

85 with furosemide presented with lower SUV and radioactivity concentration within the urinary bladder.

86 Accurate predictions of radioactivity concentrations are critical for estimating

87 ile excretion of (11)C-cholylsarcosine, with radioactivity concentrations being more than 90 times hi

88 However, the use of radium alone to predict radioactivity concentrations can greatly underestimate t

89 Tissue radioactivity concentrations for normal organs and lesio

90 1], where CROI and CREF are the mean of the radioactivity concentrations from 90 to 120 min after tr

91 We investigated the contribution to radioactivity concentrations from naturally occurring ra

92 ity coefficients were derived from the fetal radioactivity concentrations measured on the images for

93 Clinically relevant radioactivity concentrations of alpha- and beta-emitters

94 Tumor radioactivity concentrations were calculated from SPECT

95 Tumor radioactivity concentrations were high at 1 h after inje

96 e parent fraction and plasma and whole-blood radioactivity concentrations.

97 ocedures, and the ability to quantify tissue radioactivity concentrations.

98 demonstrated that 80-95% of brain uptake of radioactivity constituted binding of the radiotracers to

99 veloped a methodology for calibrating (68)Ge radioactivity content in a commercially available calibr

100 (kappa) of the natural logarithm of external radioactivity corrected for radioactive decay versus tim

101 taneously with incorporation of extracardiac radioactivity correction, gaussian fitting, and total-co

102 Peak putamen radioactivity correlated with supine systolic pressure a

103 unohistochemistry staining study showed that radioactivity count correlated with fluorescence signal

104 was assessed by fluorescent microscopy and a radioactivity count method.

105 urgically removed tissue specimens including radioactivity counting, autoradiography, immunohistochem

106 Time-radioactivity curves were extracted in 11 manually delin

107 h-old WT mice and found that, although total radioactivity declined over 2 h, of the remaining radioa

108 External radioactivity decreases versus time with first-order kin

109 ogues via liquid chromatography coupled with radioactivity detection and mass spectrometry (LC-RAD/MS

110 y assays are discontinuous, involving either radioactivity detection or coupling with antibodies.

111 In this work we present specific radiocarbon radioactivity determinations and based on them estimatio

112 h account for more than 99% of the total TRU radioactivity disposed and scheduled for disposal in the

113 led enzyme activity-dependent changes in the radioactivity distribution in the liver and tumors.

114 In the FaDu mouse model, radioactivity distribution profiles were overlapping irr

115 wis-brown Norway [LBN] to Lewis), whole-body radioactivity distribution was assessed in vivo by small

116 fusion imaging protocol that merges data on radioactivity distribution with physiologic liver mappin

117 Variation of radioactivity distribution within HCCs indicated a heter

118 per pumps in the 3 models was not related to radioactivity distribution.

119 camera images, to determine the administered radioactivity dose and whether a therapeutic dose can be

120 ng unlabeled anti-CD20 IgG therapy after the radioactivity dose provides the best efficacy and that t

121 nding to an SA of 5.7 kBq/pmol for the given radioactivity dose, and 10% occupancy was reached at 1.5

122 ant increase of the tumor-to-kidney ratio of radioactivity, enabling for the first time, to our knowl

123 was a significant correlation between tumor radioactivity estimated in vivo and in vitro (Spearman c

124 ctivity was expressed as the (11)C-verapamil radioactivity extraction ratio ((11)C-verapamil brain di

125 The alga highly incorporated radioactivity following (14)C-EE2 exposure.

126 says indicated that intracellularly retained radioactivity for (18)F-RL-I-5F7 was similar to that for

127 tal lymph nodes were excised and assayed for radioactivity for calculation of SLN percentage of injec

128 ) can contribute to an increase in the total radioactivity for more than 100 years.

129 However, natural radioactivity found in the large volumes of "produced fl

130 Extensive incorporation of radioactivity from [(35)S]cysteine into taurine was obse

131 s capability as reported by incorporation of radioactivity from [(35)S]cysteine into taurine, in prim

132 en normalized to measurements of known serum radioactivity from a venous blood sample obtained at the

133 ose-1-P, to glycogen, whereas GP transferred radioactivity from glucose-1-P but not maltose-1-P.

134 lue at peak) and a fast elimination of total radioactivity from gray and white matter areas (ratio of

135 During in vivo tests, fluorescence and radioactivity from the MOMIA were colocalized in spatial

136 released only low portions of nonextractable radioactivity giving evidence of strongly incorporated r

137 ymph node to removal of all lymph nodes with radioactivity greater than 10% of the hottest lymph node

138 o resection of all sentinel lymph nodes with radioactivity greater than 10% of the hottest lymph node

139 onic transit (defined as geometric center of radioactivity >/=2 on day 3), but not gastric emptying,

140 modulators led to increased levels of brain radioactivity; however, dynamic PET did not show differe

141 In cancer xenografts, (99m)Tc-TCP-1 radioactivity (%ID/g) was 1.01+/-0.15 in the absence of

142 Treated mice were also dissected, and radioactivities in excised aortas were quantified by gam

143 P and (125)I-2P) showed similar retention of radioactivity in both tumor and major organs except kidn

144 Whole-body scans showed radioactivity in brain and in peripheral organs expressi

145 -NOP-1A injection, the peak concentration of radioactivity in brain was high ( approximately 5-7 stan

146 The accumulation of radioactivity in different organs after intravenous admi

147 and sacrificed after the final PET scan, and radioactivity in dissected tissues was measured with a g

148 ges allowed the visualization of accumulated radioactivity in KB tumors and in the kidneys.

149 onstrated that a very high proportion of the radioactivity in monkey brain was bound specifically and

150 payload EPI, (125)I-labeled EPI showed lower radioactivity in normal organs and tumor at 48h and 144h

151 idic counting system to monitor rodent blood radioactivity in real time, with high efficiency and sma

152 ne group was injected with (3)H-cocaine, and radioactivity in the blood and brain was determined.

153 However, residual radioactivity in the blood and normal organs was consist

154 After (11)C-NOP-1A injection, peak uptake of radioactivity in the brain had a high concentration ( ap

155 injection of (11)C-dLop the concentration of radioactivity in the brain was low (standardized uptake

156 ously) resulted in a uniform distribution of radioactivity in the brain.

157 h time post-injury: the ratio of accumulated radioactivity in the diseased and healthy cardiac tissue

158 pH of 5.0-5.5, contained greater than 98% of radioactivity in the form of pertechnetate ion, and was

159 Radioactivity in the lipid fraction, as compared with th

160 radiochemical yield of 14% +/- 7%, specific radioactivity in the range of 888-3,774 GBq/mumol, and a

161 patients because of lack of interference by radioactivity in the small intestine.

162 The peak radioactivity in the thalamus was 540 (percentage standa

163 PET imaging showed that the accumulation of radioactivity in the treated tumors decreased 76% at 75

164 tion studies show a rapid and high uptake of radioactivity in the tumor, with uptake levels reaching

165 gamma-counting of radioactivity in the tumors positively correlated with c

166 lacridar, the brain PET signal corrected for radioactivity in the vasculature was low (~0.1 standardi

167 Radioactivity in the VOIs, normalized to whole-brain rad

168 Two photoproducts accounted for 15-30% of radioactivity in the water column at the end of the 63-d

169 etabolites individually accounted for <7% of radioactivity in the water or sediment.

170 and the significance of the heterogeneity of radioactivity in this important radiosensitive tissue.

171 The retention of radioactivity in tumors after administration of (64)Cu-A

172 This study demonstrated that radioactivity in tumors and the tumor-to-normal brain ra

173 Radioactivity in tumors was measured on PET/CT images an

174 PET/CT studies show specific accumulation of radioactivity in U87-stb-CXCR4 tumors, with the percenta

175 There was no detectable radioactivity in urine.

176 (HD), with approximately the same amount of radioactivity, in separate investigations 1 wk apart.

177 Radioactivity-induced charging mechanisms have been inve

178 The radioactivity-induced surface charging is highly influen

179 de nuclear reactors, verified the long-lived radioactivity inside our planet, and informed sensitive

180 The large discharge of radioactivity into the northwest Pacific Ocean from the

181 unction, the distribution of (11)C-verapamil radioactivity into these compartments is limited by bloo

182 The low brain uptake of radioactivity is consistent with (11)C-dLop being a subs

183 sue exposed to radiation emitted by internal radioactivity is often correlated with the mean absorbed

184 nd heterogeneous surface potential caused by radioactivity is reported.

185 Brain radioactivity (KBq/mL) was measured in summation images

186 While the radioactivity kept the amount of material limited to mic

187 The radioactivity level in tumors 4 h after injection was 10

188 mples, as well as to compile a data base for radioactivity levels in that region.

189 tration of [(11)C]PD153035 greatly increased radioactivity levels in the adjacent tumor compared with

190 1) levels of albumin nanoparticle-associated radioactivity located within the lung tissue (23.3+/-4.7

191 reases overall radiolabeling time and causes radioactivity loss.

192 Their radioactivity makes such compounds interesting candidate

193 tion counting and liquid chromatography with radioactivity, mass spectrometry, and UV detectors.

194 ion algorithm for the assessment of regional radioactivity may allow for accurate and reproducible se

195 alculated and compared with the well-counted radioactivity measured from the postmortem myocardial ti

196 nuous infusion of I-iothalamate and external radioactivity measurement after a single intravenous inj

197 plasma, and urine samples were collected for radioactivity measurement and plasma radiotracer metabol

198 erial venous blood samples were obtained for radioactivity measurement and radiometabolite analysis.

199 plasma, and urine samples were collected for radioactivity measurement and radiotracer stability.

200 dividual (131)I doses estimated from thyroid radioactivity measurements and were screened according t

201 P) data, computed from the tissue and plasma radioactivity measurements from the presmoking baseline

202 In addition, ex vivo radioactivity measurements of blood and of biopsies from

203 Radioactivity measurements showed predominant accumulati

204 est mean absorbed dose per unit administered radioactivity (muGy/MBq) was in the bladder wall (32.4),

205 ) were achieved from starting (18)F-fluoride radioactivities of 40-44 GBq.

206 Lower radioactivities of I-131 could provide similar outcomes

207 sional doses being noted using fixed 100 mCi radioactivities of I-131, no dose-effective relationship

208 adiochemical yield and purity, with specific radioactivities of more than 83.92 GBq/mumol.

209 al (124)I-BTT-1023 PET studies with injected radioactivity of 0.5-0.7 MBq/kg may be justified.

210 bismuth, and polonium isotopes, to the total radioactivity of hydraulic fracturing wastes.

211 Radioactivity of nest samples was in the range 479-143,3

212 th this finding, measurement of the specific radioactivity of PC in plasma and liver indicated that 5

213 Another interesting feature is the radioactivity of some compounds, which makes them excell

214 With this approach, the specific radioactivity of the alloyed gold nanoparticles could be

215 ermoluminescent dosimeters, and by measuring radioactivity of the nest material.

216 s, has been employed to study the effects of radioactivity on particle aggregation kinetics in air.

217 en performed to investigate the influence of radioactivity on surface charging and aggregation kineti

218 y with human tissue revealed accumulation of radioactivity only in AD brain tissues in which Abeta pl

219 amples, limit this work because they rely on radioactivity or fluorescence and require bulky instrume

220 Limited redistribution of radioactivity out of the peritoneal cavity to circulatin

221 the PET signal, essentially by accumulating radioactivity over time.

222 ayed by measuring changes in cell-associated radioactivity over time.

223 )F-l-FEHTP was between 48% and 113% of added radioactivity per milligram of protein within 60 min at

224 Besides total radioactivity, plasma samples were analyzed by radio-hig

225 ancer cells, with retention of intracellular radioactivity predicted to occur via a putative (18)F-FP

226 ategies decrease the circulation time of the radioactivity, reduce the uptake of the radionuclide in

227 opulations in the same tissue may contain no radioactivity, referred to as labeled and unlabeled cell

228 The large inventory of radioactivity released during the March, 2011 Fukushima

229 Radioactivity released from disasters like Chernobyl and

230 of March 11, 2011, resulted in unprecedented radioactivity releases from the Fukushima Dai-ichi nucle

231 of radioactivity was observed, whereas most radioactivity remained trapped in the endocrine cells.

232 At 30 min after injection, 37% of plasma radioactivity represented unmetabolized (18)F-GE-179.

233 (37.2% +/- 4.0% and 37.6% +/- 4.1% of total radioactivity, respectively).

234 or (238)U, corresponding to 4 and 25 muBq/kg radioactivity, respectively.

235 These levels correspond to 25 and 25 muBq/kg radioactivity, respectively.

236 ffinity binders provided 2-fold-higher tumor radioactivity retention at 24 h.

237 ctron antineutrinos from terrestrial natural radioactivity, reveal the amount of uranium and thorium

238 dge of the transport of the Fukushima marine radioactivity signal to the eastern North Pacific.

239 In addition, the radioactivity signal within the urinary bladder was lowe

240 We demonstrate the first evidence of radioactivity-synchronized fluorescence quenching of a n

241 s cell lines incorporated significantly more radioactivity than their normal counterparts.

242 We now aim to establish the lower limit of radioactivity that can be administered to patients and t

243 ic chemistry laboratories, the importance of radioactivity, the basics of Np decay and its ramificati

244 s retained greater than 52% and 70% of their radioactivity through 60 days in the prostate and pancre

245 Radioactivity time integrals are more robustly estimated

246 The partitioning of radioactivity to different organs and tissues was measur

247 r results indicated that the distribution of radioactivity to EGFR-overexpressing tumors was affected

248 and endotoxinMD-2 complexes of high specific radioactivity to measure: 1) interaction of recombinant

249 To link the radioactivity to possible health impairments, we calcula

250 ouse tumor model (Panc-02) that RL delivered radioactivity to the metastases and less abundantly to p

251 he recent transport history of the Fukushima radioactivity tracer plume through the northeast Pacific

252 gnificant, ongoing environmental releases of radioactivity, triggering a mandatory evacuation of a la

253 retention, correspondingly, of internalized radioactivity under hypoxic conditions relative to 34.8%

254 No evidence of radioactivity uptake in bone was observed.

255 The radioactivity uptake in joints was quantified and correl

256 The radioactivity uptake in nontumor tissue was higher than

257 croPET studies affirm that this differential radioactivity uptake in spinal cords of EAE versus contr

258 Early (6-24 h) radioactivity uptake in the gastrointestinal region was

259 abeling with [(99m)Tc(CO)3](+) but increases radioactivity uptake in the liver.

260 Besides, significant radioactivity uptake in the pituitary gland was observed

261 ter tariquidar pretreatment in both species, radioactivity uptake in these organs decreased by 35% to

262 analysis with cerebellar reference input, as radioactivity uptake ratios between the frontal cortex (

263 High radioactivity uptake was seen in liver, followed by sple

264 in rhesus monkey, [(18)F]11 gave high brain radioactivity uptake, reflecting the expected distributi

265 es to assess regional distribution of (89)Zr radioactivity was also performed.

266 Plasma and urine radioactivity was assessed over 24 hours.

267 Greater than 82% of the injected radioactivity was cleared through the urinary system by

268 Distribution of radioactivity was determined via PET at 60 min after rad

269 determine whether the increased tumor (64)Cu radioactivity was due to increased cellular uptake of (6

270 on between SPECT-quantified and well-counted radioactivity was fair (R(2) = 0.19, y = 0.50x + 0.05, P

271 e serum as trichloroacetic acid-precipitable radioactivity was greatly reduced in Mct8-KO mice.

272 In patients, radioactivity was high in regions expected to contain am

273 4)C-labeled product was maltohexaose, and no radioactivity was in maltopentaose, demonstrating that m

274 o contain amyloid-beta, whereas in controls, radioactivity was low and homogenously distributed.

275 Accumulation of radioactivity was low in other organs, with the exceptio

276 itoneally into ApoE knockout mice (n=6), and radioactivity was measured using a gamma counter.

277 Less than 3% of applied radioactivity was mineralized to (14)CO2.

278 the remaining 50 min, suggesting that brain radioactivity was most likely parent radioligand, as sup

279 Brain uptake of radioactivity was negligible at baseline and increased o

280 esent in blood ( approximately 40% of plasma radioactivity was nonparent 3 h after injection), no sig

281 In the exocrine cells, a rapid efflux of radioactivity was observed, whereas most radioactivity r

282 in orexin-A-stimulated cells, the AA-derived radioactivity was released as two distinct components, i

283 Most of the radioactivity was retained in the circulation system at

284 Brain radioactivity was strikingly higher in the LPS-treated m

285 ivity in the VOIs, normalized to whole-brain radioactivity was taken as a surrogate index of glucose

286 e from (18)F-FDG samples containing decaying radioactivity was transmitted through an optical fiber b

287 demonstrated that intracellular retention of radioactivity was up to 1.5-fold higher for *I-SGMIB-Nan

288 Tissue (18)F radioactivities were determined from quantitative analys

289 Total time integrals of radioactivity were computed for each model and averaged

290 rkably, little fractions of the internalized radioactivity were detected in the blood and muscle tiss

291 Detectable concentrations of drug-related radioactivity were documented in the central nervous sys

292 The highest mean levels of gray matter radioactivity were seen in the putamina and peaked at 7.

293 tate cancer xenografts with increased (64)Cu radioactivity were visualized previously by PET using (6

294 ssue may contain widely different amounts of radioactivity, whereas other cell populations in the sam

295 estimated by multiplying fludeoxyglucose F18 radioactivity with dose coefficients.

296 ximately 3 h to estimate the uptake of (18)F radioactivity with respect to time for the pharmacokinet

297 logic analysis showed good colocalization of radioactivity with TAM-rich areas in tumor sections.

298 ans except the kidneys showed low background radioactivity, with especially low activities in the liv

299 ed on the dissected pancreas to localize the radioactivity within the pancreatic tissue.

300 Accumulation of radioactivity within the tumor periphery colocalized wit