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1 onitor the therapeutic effect of pretargeted radioimmunotherapy.
2 harmaceuticals; 37.9% did not treat NHL with radioimmunotherapy.
3 r institution accepted Medicare patients for radioimmunotherapy.
4 ne for a more informed design of combination radioimmunotherapy.
5 e myeloid leukaemia 5 months after receiving radioimmunotherapy.
6 tial to be more effective than standard-dose radioimmunotherapy.
7 n tumors typically drops significantly after radioimmunotherapy.
8 ng the response of non-Hodgkin's lymphoma to radioimmunotherapy.
9 ease toxicity of subsequent (131)I-rituximab radioimmunotherapy.
10 before radioimmunotherapy and at 12 wk after radioimmunotherapy.
11 brane antigen, has potential as an agent for radioimmunotherapy.
12 , such as with immunoSPECT and immunoPET, or radioimmunotherapy.
13 L) after treatment with ibritumomab tiuxetan radioimmunotherapy.
14 -Fc H310A/H435Q as a promising candidate for radioimmunotherapy.
15 NHL and 1.9 years (range, 0.4 to 6.3) after radioimmunotherapy.
16 ith multistep immune targeting approaches to radioimmunotherapy.
17 phoma has led to a resurgence of interest in radioimmunotherapy.
18 ionuclides, as currently practiced in cancer radioimmunotherapy.
19 rter residence time that limits their use in radioimmunotherapy.
20 ecules can be used as effective vehicles for radioimmunotherapy.
21 xamined in patients with lymphoma treated by radioimmunotherapy.
22 3, and J591) and their potential utility for radioimmunotherapy.
23 targeting may be involved in the success of radioimmunotherapy.
24 ffer advantages compared with antibody-based radioimmunotherapy.
25 vere during CHOP chemotherapy than following radioimmunotherapy.
26 arted induction treatment; 57 (80%) received radioimmunotherapy.
27 Analyses included only patients who received radioimmunotherapy.
28 ive of improved PFS after (131)I-tositumomab radioimmunotherapy.
29 he clinically emerging method of pretargeted radioimmunotherapy.
30 cells: targeted nanospheres and pretargeted radioimmunotherapy.
31 or dose than is possible with nonpretargeted radioimmunotherapy.
32 cute leukemias administered externally or as radioimmunotherapy.
33 with antibody drug conjugates, and dosing in radioimmunotherapy.
34 Bone marrow is usually dose-limiting for radioimmunotherapy.
35 linical biodistribution studies and clinical radioimmunotherapies.
36 was performed on 13 patients at 24 wk after radioimmunotherapy, 12 of whom did not receive interval
37 diagnosed with tMDS/tAML prior to receiving radioimmunotherapy; 2 (8%) had no pathologic or clinical
38 108 lesions evaluated at 12 and 24 wk after radioimmunotherapy, 49 resolved at 12 wk and remained re
41 6 received autologous HCT 3 d after (211)At-radioimmunotherapy, after lymph node and bone marrow bio
42 oal of this work was to determine an optimal radioimmunotherapy agent for further development against
43 p53-negative tumor-bearing mice treated with radioimmunotherapy alone or combined with cisplatin show
44 HCT116 tumor-bearing mice, receiving either radioimmunotherapy alone or in combination with cisplati
45 ately 30% of its maximum tolerated dose, and radioimmunotherapy alone, at its maximum tolerated dose,
47 ty-six patients received full-radiation-dose radioimmunotherapy and 12 received attenuated doses beca
48 0) and underwent 18F-FDG PET/CT scans before radioimmunotherapy and at 12 wk after radioimmunotherapy
50 -PD-L1 antibody for radionuclide imaging and radioimmunotherapy and highlight a new opportunity to op
51 In this study, we used EGFR as a target for radioimmunotherapy and hypothesized that EGFR-directed r
54 ysplastic syndrome 28 months after receiving radioimmunotherapy and one patient developed acute myelo
57 vivo purging with rituximab, the utility of radioimmunotherapy and, finally, the evolving strategy o
58 ed systems, lessons learned from pretargeted radioimmunotherapy, and important considerations for har
60 receiving radionuclide therapy, particularly radioimmunotherapy, and the relatively long pathlength o
62 hese larger formats may be more suitable for radioimmunotherapy applications, evidenced by the precli
64 ive allogeneic transplantation and high-dose radioimmunotherapy are topics of ongoing investigation.
67 toxicity is highly unlikely in standard dose radioimmunotherapy but should be considered a potential
69 es could potentially play a valuable role in radioimmunotherapy by more stably encapsulating radionuc
70 ates the opinions and patterns of the use of radioimmunotherapy by nuclear physicians, affiliated res
71 the potential for improving the efficacy of radioimmunotherapy by targeting other NHL cell surface a
72 ctivity retained in the body after high-dose radioimmunotherapy can damage PBSCs if they are transfus
73 otherapy and hypothesized that EGFR-directed radioimmunotherapy can deliver a continuous lethal radia
75 re eradicated in mice treated with anti-EGFR radioimmunotherapy combined with chemotherapy and PARP i
80 y (mAb; CA12.10C12) protein dose for (211)At-radioimmunotherapy, extending the analysis to include in
82 lenge, rendering (225)Ac@GNTs candidates for radioimmunotherapy for delivery of (225)Ac(3+) ions at h
83 nt the efficacy and decrease the toxicity of radioimmunotherapy for disseminated murine leukemia.
84 le and 13 female; median age, 64 y) received radioimmunotherapy for NHL (20 received (90)Y-ibritumoma
88 of targeted monoclonal antibody therapy and radioimmunotherapy for orbital and adnexal non-Hodgkin's
89 antibody 8H9 has been successfully used for radioimmunotherapy for patients with B7-H3(+) tumors.
91 n lymphoma patients after (131)I-tositumomab radioimmunotherapy for potential use in treatment planni
92 viously treated patients, and 4.6 years from radioimmunotherapy for previously untreated patients.
94 mbination therapies using systemic anti-EGFR radioimmunotherapy for the treatment of recurrent and me
95 eview will present the latest information on radioimmunotherapy for treatment of hematologic malignan
96 c information useful for titrating doses for radioimmunotherapy, for patient risk stratification and
97 m baseline in 244 target lesions 12 wk after radioimmunotherapy (from 6.51+/-4.05 to 3.94+/-4.41; P<0
99 em-cell transplant or myeloablative doses of radioimmunotherapy given in conjunction with stem-cell s
100 owed delayed tumor growth in the pretargeted radioimmunotherapy group, corresponding with their prolo
101 d consolidation as a possible indication for radioimmunotherapy had significantly fewer concerns abou
102 ividuals who perceived a negative future for radioimmunotherapy had significantly more concerns about
106 (I)-labeled monoclonal antibodies (MAbs) for radioimmunotherapy has been the rapid diffusion of iodot
110 therapies, both unconjugated antibodies and radioimmunotherapy, have had a significant impact on the
111 treated at our centers with either high-dose radioimmunotherapy (HD-RIT) using 131I-anti-CD20 (n = 27
112 ioimmunotherapy predicted a higher growth of radioimmunotherapy if they could administer it in their
114 an intravenous fractionated regimen of alpha-radioimmunotherapy in a subcutaneous tumor model in mice
115 In this first preclinical study of anti-EGFR radioimmunotherapy in breast cancer, we found that anti-
116 n vivo purging with rituximab and the use of radioimmunotherapy in conditioning regimens may further
117 ficacy with the combination of cetuximab and radioimmunotherapy in CRC, which could potentially trans
118 role of kinetic and transport parameters of radioimmunotherapy in maximizing the therapeutic ratio,
119 atuzumab tetraxetan ((90)Y-DOTA-epratuzumab) radioimmunotherapy in refractory or relapsed CD22-positi
123 nical trials and reinvigorate enthusiasm for radioimmunotherapy in the treatment of malignancies, par
125 on make tomoregulin an attractive target for radioimmunotherapy, in which tomoregulin-specific antibo
126 scientific concerns, barriers to the use of radioimmunotherapy included difficulty in referral, perc
127 White blood cell count analysis after alpha-radioimmunotherapy indicated bone marrow recovery for th
130 w (RM) is often the primary organ at risk in radioimmunotherapy; irradiation of marrow may induce sho
136 py in breast cancer, we found that anti-EGFR radioimmunotherapy is safe and that TNBC orthotopic tumo
138 table response rates have been observed when radioimmunotherapy is used as front-line treatment in pa
143 Cytogenetic testing before treatment with radioimmunotherapy may identify existing chromosomal abn
146 t of these bsRICs for dual-receptor-targeted radioimmunotherapy of BC coexpressing HER2 and EGFR, inc
149 mply that the optimal strategy for A33-based radioimmunotherapy of colon cancer will consist of a mul
152 the absorbed dose (AD) to the artery wall in radioimmunotherapy of NHL is of potential concern for de
153 OTA chelate represents an improved agent for radioimmunotherapy of non-Hodgkin's lymphoma, with an in
161 tibody that pretargeted (90)Y-hapten-peptide radioimmunotherapy or a directly radiolabeled, humanized
162 lymphoma and can be used in combination with radioimmunotherapy or standard chemotherapy for a more d
164 thought it took too much time to administer radioimmunotherapy (P < 0.01) and had concerns about the
168 Finally, the 3D methods were applied to a radioimmunotherapy patient, and the mean tumor absorbed
169 efficacy and safety of anti-CEA pretargeted radioimmunotherapy (pRAIT) in rapidly progressing metast
171 with a positive outlook about the future of radioimmunotherapy predicted a higher growth of radioimm
172 We now show the superiority of pretargeted radioimmunotherapy (PRIT) compared with conventional rad
176 recently reported a novel 3-step pretargeted radioimmunotherapy (PRIT) strategy based on a glycoprote
183 ies alone or in combination with pretargeted radioimmunotherapy (PT-RAIT) or radioimmunotherapy, and
185 safety, and clinical activity of radretumab radioimmunotherapy (R-RIT) were evaluated in 18 relapsed
186 d marrow absorbed dose in patients receiving radioimmunotherapy (RAIT) has not been highly predictive
187 improved therapeutic index with pretargeted radioimmunotherapy (RAIT) using a DNL-constructed tri-Fa
188 w that anti-GPA33 DOTA-PRIT will be a potent radioimmunotherapy regimen for GPA33-positive colorectal
192 s the most current allogeneic HCT data using radioimmunotherapy (RIT) and focuses on recent trials in
197 was 6 years from diagnosis and 2 years from radioimmunotherapy (RIT) for previously treated patients
199 e treatment of non-Hodgkin's lymphoma (NHL), radioimmunotherapy (RIT) has finally come of age as a ne
200 or groups as potential yttrium chelators for radioimmunotherapy (RIT) have been prepared via a conven
201 ry radiosensitive, but the potential role of radioimmunotherapy (RIT) in the management of plasmacyto
202 (375 mg/m(2)) and proceeded to fractionated radioimmunotherapy (RIT) only if a repeat BM biopsy demo
205 d a conditioning regimen employing anti-CD45 radioimmunotherapy (RIT) replacing total body irradiatio
207 anti-DR) antibodies (Abs) and of pretargeted radioimmunotherapy (RIT) using Ab-streptavidin (SA) conj
211 ium-90 (Y-90) ibritumomab tiuxetan (Zevalin) radioimmunotherapy (RIT) was safe and effective for rela
215 gh metastatic breast cancer is responsive to radioimmunotherapy (RIT), a systemic targeted radiation
216 targeting and tumor control by CD20-directed radioimmunotherapy (RIT), but had no impact on targeting
217 ed with either external beam radiotherapy or radioimmunotherapy (RIT), which joins the selectivity of
223 An antibody-targeted radiation therapy (radioimmunotherapy, RIT) employs a bifunctional ligand t
224 als are currently underway to further define radioimmunotherapy's role in the treatment of lymphomas.
227 d with monotherapy, combining cetuximab with radioimmunotherapy significantly and synergistically red
231 inal half-life and serum clearance suited to radioimmunotherapy (T1/2beta, 100.24 +/- 20.92 h, and cl
232 d comparative assessments using conventional radioimmunotherapy targeting CD20, CD22, and HLA-DR on h
234 meters and may be particularly effective for radioimmunotherapy targeting minimal residual disease (M
236 onjugates are better candidates for targeted radioimmunotherapy than are antibodies targeting PSMA(in
238 derable success in improving the efficacy of radioimmunotherapy, the pretargeting strategy remains un
239 dies targeting lymphoma-associated antigens, radioimmunotherapy, therapeutic vaccination and allogene
240 zed that selective ablation of T cells using radioimmunotherapy together with postgrafting immunosupp
242 e tumor absorbed radiation doses in STI571 + radioimmunotherapy-treated mice compared with PBS + radi
249 unotherapy (PRIT) compared with conventional radioimmunotherapy using a recombinant tetravalent singl
253 assess activity and toxicity of fractionated radioimmunotherapy using anti-CD22 (90)Y-epratuzumab tet
255 ated the preclinical efficacy of combination radioimmunotherapy, using a humanized (131)I-labeled ant
256 bolic activity was assessed before and after radioimmunotherapy visually and quantitatively by lean m
259 n percentage decline in platelet count after radioimmunotherapy was greater in the (90)Y-ibritumomab
261 ed survey with 13 broad questions related to radioimmunotherapy was sent electronically to 13,221 Soc
262 various sizes after intraperitoneal (211)At-radioimmunotherapy, we used an in-house-developed Monte
263 emarkable improvements in tumor responses to radioimmunotherapy were discovered after the inclusion o
266 this study was to determine the efficacy of radioimmunotherapy when using (90)Y-labeled cetuximab an
267 trials have shown the promise of pretargeted radioimmunotherapy, which leverages the specificity of a
269 umor-to-red marrow dose ratio was higher for radioimmunotherapy with (177)Lu-cG250 than for radioimmu
273 cts on tumor growth after fractionated alpha-radioimmunotherapy with (211)At-MX35-F(ab')2 was strong
274 cts on tumor growth after fractionated alpha-radioimmunotherapy with (211)At-MX35-F(ab')2 was strong
277 e examine the role of p53 in the response to radioimmunotherapy with (64)Cu-DOTA-cetuximab in KRAS-mu
279 dioimmunotherapy with (177)Lu-cG250 than for radioimmunotherapy with (90)Y-cG250, indicating that (17
286 This clinical trial evaluated standard-dose radioimmunotherapy with a chemotherapy-based transplanta
287 ternal gamma-beam radiation, we investigated radioimmunotherapy with an anti-CD45 mAb labeled with th
288 ation derived from a Cs-137 source, systemic radioimmunotherapy with an I-131-conjugated monoclonal a
289 a dose of 2 mCi/kg Bi, further trials using radioimmunotherapy with Bi for nonmyeloablative HCT seem
290 study demonstrates that dose deescalation of radioimmunotherapy with Bi labeled to anti-CD45 or anti-
293 the authors demonstrated that pretransplant radioimmunotherapy with the alpha-emitter bismuth-213 (B
294 R could be treated by dual-receptor-targeted radioimmunotherapy with these bsRICs labeled with the be
295 analysis shows the feasibility of outpatient radioimmunotherapy with tositumomab and (131)I-tositumom
296 oped determining patient releasability after radioimmunotherapy with tositumomab and (131)I-tositumom
297 he limitations of conventional, or one-step, radioimmunotherapy, with initial preclinical and clinica
298 Almost 30% (29.6%) of the responders thought radioimmunotherapy would probably grow and 38.0% thought
299 Seventy-nine (36.6%) responders thought radioimmunotherapy would probably grow in importance, an
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