ライフサイエンスコーパス: radioiodinate

1 n be tagged with a fluorescent rhodamine and radioiodinated.

2 ide ester of 4-azidobenzoylglycine (ABG) and radioiodinated.

3 IMP-R4 was radioiodinated (0.13 mumol per 3.7 GBq of (131)I) at a p

4 In this study, two novel radioiodinated 1,4-benzodiazepines, (S)-1-(3-iodophenyl)

5 nibody was 5.7 +/- 0.1% ID/g, similar to the radioiodinated 10H8 minibody.

6 Carrier-free radioiodinated [125I]IAPEGlyMER and [125I]TBZ-AIPP were

7 Carrier-free radioiodinated [125I]IAS was used to photolabel epitope-

8 compared with a maximal ratio of 9.8:1 using radioiodinated 1F5.

9 )-labeled hSSTr2-binding peptide (P2045) and radioiodinated 2'-deoxy-2'-fluoro-beta-D-arabinofuranosy

10 Biodistribution studies with the radioiodinated 3(R)- and 3(S)-isomers of 15-(p-iodopheny

11 Radioiodinated 3(R)-(+)- and 3(S)-(-)-15-(p-iodophenyl)-

12 pound 11d was able to displace the reference radioiodinated 5-HT(4)R antagonist (1-butylpiperidin-4-y

13 Radioiodinated 8 thus appears to be a suitable radioliga

14 th mouse brain sections, the distribution of radioiodinated 8 was consistent with that of brain CB1 r

15 Radioiodinated 8, (R)-8, and (S)-8 were prepared by radi

16 microaggregates of fluorescently labeled or radioiodinated A beta peptide 1-42.

17 etween hormone and receptor, we designed and radioiodinated a bioactive, photoreactive PTH agonist, (

18 rm of (131)I (residualizing (131)I) involves radioiodinating a small molecular entity, conjugating it

19 physiological concentrations (0.5-0.7 nM) of radioiodinated Abeta1-40 and seven plasma samples with A

20 umulation in blood of intracamerally infused radioiodinated albumin at two intraocular pressure level

21 n uptake, we next studied the endocytosis of radioiodinated albumin using aortic ring segments from w

22 Interestingly, little or no uptake of radioiodinated albumin was observed in the aortic segmen

23 Pulmonary capillary leak was estimated using radioiodinated albumin.

24 Saturation experiments indicate that radioiodinated alpha-conotoxin MI binds to TE671 cell ho

25 e tested for IgG radioimmunoprecipitation of radioiodinated alpha-dendrotoxin ((125)I-alphaDTX)-label

26 The radioiodinated analog 125I-Bpa1-PTH-(1-34) cross-linked

27 n in a competition binding assay to displace radioiodinated analogue of CP-96,345.

28 4 kDa, half-life for NO release 20 days) was radioiodinated and found by intravital gamma-imaging to

29 Modified UBLs were radioiodinated and incubated with cell lysates prepared

30 ), Tyr(3), Arg(7), Phe(13)]alpha-factor, was radioiodinated and used as a probe for Ste2p, the GPCR f

31 The azido analogue, 16b, was radioiodinated and used to photolabel human DAT-transfec

32 Alpha-conotoxin MI was subsequently radioiodinated, and its properties were further evaluate

33 and an isotype-matched control antibody were radioiodinated, and the pharmacokinetics and localizatio

34 In developing radioiodinated antagonists for in vivo imaging of 5-HT1A

35 as investigated, using both biotinylated and radioiodinated antibodies (Abs).

36 With the increased use of radioiodinated antibodies, for therapy and imaging, this

37 Radioiodinated antibody and antibody fragments with (125

38 The search for a radioiodinated AR ligand prompted us to synthesize 4-[4,

39 ew lead for the development of high-affinity radioiodinated AR radioligands.

40 PT was radioiodinated at a high specific activity and possessed

41 Radioiodinated benzamide N-[2-(1'-piperidinyl)ethyl]-3-[

42 ical yields in the large-scale production of radioiodinated benzamides required for clinical applicat

43 Three different radioiodinated benzamides, [125I]PIMBA, 4-[125I]iodo-N-[

44 ully characterized and then converted to the radioiodinated BMIPP isomers.

45 Upon photolysis, radioiodinated [Bpa23]PTHrP covalently and specifically

46 oaffinity labeling of the M174A mutant using radioiodinated Bpa4-SP gave the unexpected result of an

47 The site of covalent attachment of radioiodinated Bpa8-SP is thus restricted to a residue w

48 oaffinity labeling of the M181A mutant using radioiodinated Bpa8-SP resulted in a marked reduction in

49 In the present study, we used radioiodinated Bpa8-SP to covalently label with high eff

50 tau and synuclein proteins and suggests that radioiodinated BSB derivatives or related ligands may be

51 Radioiodinated BTT-1023 cleared rapidly from blood circu

52 In this study, we preclinically evaluated radioiodinated BTT-1023 for inflammation imaging.

53 The radioiodinated BTT-1023 was able to detect mild inflamma

54 Rabbits were intravenously injected with radioiodinated BTT-1023.

55 lls after lysosomal catabolism of antibodies radioiodinated by conventional methods, whereas small mo

56 throcytes and inside-out vesicles were [125I]radioiodinated by lactoperoxidase in the same vessel.

57 considerably more stable in vivo than those radioiodinated by the direct electrophilic method.

58 PT was radioiodinated by the lactoperoxidase method which prefe

59 Biotinylated or radioiodinated C1q (*C1q) bound specifically to transfec

60 Conversely, the radioiodinated CCK(2) receptor-selective compound 7 show

61 l study directly compared L8A4 labeled using radioiodinated D-KRYRR and L-KRYRR, and confirmed the ro

62 Using radioiodinated DBP as a probe, neutrophils released 70%

63 In the present study, radioiodinated DBP was used as a probe to characterize b

64 Specific binding of a radioiodinated derivative ((125)I-alpha-CtxMII) was iden

65 ifically and efficiently photolabeled with a radioiodinated derivative of Bpa(4)-SP.

66 We recently reported that a radioiodinated, diethylenetriaminepentaacetic acid-appen

67 A series of radioiodinated, diethylenetriaminepentaacetic acid-appen

68 ulosis-associated inflammation, we evaluated radioiodinated DPA-713, a synthetic ligand of TSPO, for

69 F acts as a soluble receptor analog, binding radioiodinated DT and preventing its binding to the cell

70 n essentially heparin-independent binding of radioiodinated DT to cells.

71 However, the possibility existed that radioiodinated DT-HB-EGF complexes associate with cells

72 ddition, we have synthesized a carrier-free, radioiodinated fenpropimorph-like photoaffinity label, 1

73 synthesized and tested IAmF in carrier-free radioiodinated form ([(125)I]IAmF).

74 The radioiodinated form of L-750,667 bound specifically to t

75 When (125)IQ(2-P), the radioiodinated form of the water-soluble prodrug, was in

76 The radioiodinated fragments and the radiometal-labeled mini

77 o CD20-positive tumors was observed with the radioiodinated fragments.

78 d from healthy fasting volunteers along with radioiodinated human serum albumin (RIHSA).

79 ace radiolabeling of GLUT4 whereas uptake of radioiodinated human transferrin does not show appreciab

80 When examined using radioiodinated IL-2 or IL-15, each cytokine accumulated

81 ide-out vesicles and intact cells were [125I]radioiodinated in the same suspension, tyrosine 486 was

82 studies performed on activated T cells with radioiodinated KL were consistent with the expression of

83 SDS-PAGE analysis of the radioiodinated leptin after 60 min of uptake revealed in

84 Radioiodinated leptin was intravenously injected into ob

85 ino-tetralin) was reported to be a selective radioiodinated ligand for dopamine D2-like receptors.

86 e results of experiments characterizing this radioiodinated ligand in vitro.

87 e its binding utilizing structurally related radioiodinated ligands selective for CCK receptor subtyp

88 These findings strongly suggest that the new radioiodinated ligands, [125I]12 (ISB), [125I]13 (IMSB),

89 ntion studies showed that the receptor-bound radioiodinated linear alpha-MSH analog NDP was released

90 ns were studied using a chemically modified, radioiodinated LPS containing a covalently linked, UV li

91 Radioiodinated mAb 11-1F4 retained immunoreactivity, as

92 ll as the factors required for production of radioiodinated MAb in high yield and with high specific

93 after internalization and catabolism of the radioiodinated MAbs.

94 Radioiodinated MBL bound to recombinant soluble CR1 (sCR

95 In this study, by using radioiodinated MCP-2, we identified high affinity bindin

96 Radioiodinated metaiodobenzylguanidine ((123)I-mIBG) sci

97 Radioiodinated minibody also cleared rapidly from the ci

98 A radioiodinated minibody and a radioiodinated scFv-Fc fra

99 Equilibrium binding studies with radioiodinated MIP-1 alpha were consistent with the indu

100 The in vivo behavior of radioiodinated MORAb-004 was characterized in mice beari

101 Radioiodinated MSP and MSP beta chain both bound specifi

102 Radioiodinated N33A showed high affinity binding to huma

103 screening for competitive binding against a radioiodinated neuropeptide FF analogue, 5-(dimethylamin

104 In conclusion, compound 9 is an excellent radioiodinated nonpeptidic antagonist ligand for direct

105 The radioiodinated peptide alone cleared quickly from the bl

106 1In and pretargeted with the bs-mAb, and the radioiodinated peptide alone.

107 These data suggest that radioiodinated peptide p5R may be optimal for the in viv

108 oid and stomach uptake was observed with the radioiodinated peptide several hours after injection (an

109 The [125I]radioiodinated peptides isolated by the immunoadsorbent

110 zation data showed that approximately 90% of radioiodinated peptides were internalized at 2 h in cult

111 The ability of radioiodinated phospholipid analogs to accumulate in bre

112 Radioiodinated phospholipid ether analogues have shown a

113 Cross-linking of the IRBCs with a radioiodinated photoactivable C4S dodecasaccharide label

114 Radioiodinated photoactivatable photoprobes can provide

115 ability of LBP to inhibit cross-linking of a radioiodinated, photoactivatable LPS derivative to mCD14

116 novel strategically positioned carrier-free, radioiodinated photoaffinity labels specifically designe

117 ly developed sulfhydryl-reactive, cleavable, radioiodinated photocross-linking reagent: methanesulfon

118 t on rat submaxillary gland membranes with a radioiodinated photoreactive derivative of SP, p-benzoyl

119 ified as the sites of covalent attachment of radioiodinated, photoreactive derivatives of SP containi

120 TPP group resulted in a clean separation of radioiodinated PNA from unlabeled PNA, yielding a high-s

121 and poor labeling encountered when trying to radioiodinate PNAs directly in solution was developed.

122 molecules from detergent extracts of surface-radioiodinated PRBCs using several endothelial cell rece

123 eniently assembled by "click chemistry." Two radioiodinated probes, [125I]10a and [125I]10b, and two

124 Use of [*I]SIB yields radioiodinated proteins that are considerably more stabl

125 of the in vivo radiolabeled subunits and the radioiodinated purified enzyme shows that the yeast olig

126 In the no-carrier-added synthesis of radioiodinated rhodamine 123, direct labeling of rhodami

127 retention in tumor in comparison to directly radioiodinated RS7, but the nontarget uptakes differed s

128 oreactivities comparable to that of directly radioiodinated RS7.

129 as 21.3+/-1.3, 9.8+/-1.3, and 17.3+/-1.1 for radioiodinated [sc(Fv)2]2, sc(Fv)2, and IgG, respectivel

130 iodistribution studies examining a series of radioiodinated scFv mutants with affinities ranging from

131 A radioiodinated minibody and a radioiodinated scFv-Fc fragment produced excellent, high

132 Cross-linking experiments performed with radioiodinated sFRP-1 provided definitive evidence that

133 reagents and the effect of these reagents on radioiodinated SP binding affinity and dissociation rate

134 We report a series of radioiodinated styrylpyridines as single photon emission

135 Addition of radioiodinated synthetic A beta 1-40 to the cultures or

136 in) were successfully produced, as well as a radioiodinated tetrazine, through a concomitant oxidatio

137 We have used this procedure to radioiodinate the four stereoisomers of [123I]IQNB.

138 lactoperoxidase method which preferentially radioiodinated the S1 subunit.

139 raperitoneal dosing with lipopolysaccharide, radioiodinated tyrosinamide N-linked oligosaccharides we

140 specific, isotype-matched P3X63Ag8 mAb, both radioiodinated using SIPC.

141 Radioiodinated variants had similar tumor-to-organ ratio

142 W97ALck incorporated more of the radioiodinated version of palmitic acid, 16-[(125)I]iodo

143 rin-binding peptide designated p5 that, when radioiodinated, was capable of selectively imaging syste

144 dded samples of 13a, 13b, 16a, 16b, and 16e (radioiodinated with 125I) were successfully prepared.

145 ulated brachial vein and artery using leptin radioiodinated with 2 isotopes of iodine (125I and 131I)