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1 ]sulfonyl fluorides as synthons for indirect radiolabeling.
2 n inverse stoichiometries used for efficient radiolabeling.
3 3) that served as an immediate precursor to radiolabeling.
4 rometry, tryptic peptide analysis, and (32)P radiolabeling.
5 abeled leukocytes was evaluated at 3 h after radiolabeling.
6 phatidylinositide (Ptide) metabolism without radiolabeling.
7 ble to rapidly study ADME/PK in vivo without radiolabeling.
8 he substrate variability caused by continual radiolabeling.
9 stability of the scFv's were analyzed after radiolabeling.
10 and noncollagenous proteins was measured by radiolabeling.
11 phorylation sites of ICP27 following in vivo radiolabeling.
12 te and error associated with traditional 32P radiolabeling.
13 simplified design for single-step kit-based radiolabeling.
14 hydrazino-nicotinamide (S-HYNIC) followed by radiolabeling.
15 enetriaminepentaacetic acid to allow (111)In radiolabeling.
16 ng site-specific conjugation of chelates for radiolabeling.
17 TE, which was stored in 50-nmol aliquots for radiolabeling.
18 te/HCl (pH 4.5) solution suitable for direct radiolabeling.
19 acyclononane-1,4,7-triacetic acid for (64)Cu radiolabeling.
20 ared to be due to the use of a procedure for radiolabeling (111)In-ibritumomab tiuxetan that differed
21 ial agents for mapping human SERT by PET and radiolabeling 37 with iodine-123, which could afford the
22 n types I and V, determined by (14)C-proline radiolabeling; (4) by pepsin digestion and analysis of c
23 modified with desferoxamine for zirconium-89 radiolabeling ((89)Zr-DNP) and a near-infrared fluorochr
26 ction method together with mass spectral and radiolabeling analyses, we established that l-SMM is a m
29 ion by the modified probe was assessed using radiolabeling and a standard chronocoulometry method; bo
38 atalysis, we conducted a series of catalytic radiolabeling and kinetic experiments on the C-terminal
39 chondroitin sulfate determined by (35)SO(4) radiolabeling and measuring the sensitivity to endo-beta
41 affinity for integrin alphavbeta6, for (18)F radiolabeling and PET imaging of BxPC3 pancreatic adenoc
43 nd purification requires about 2-3 h and the radiolabeling and postlabeling purification requires abo
44 develop a simple, remote, "1-pot" method of radiolabeling and purification for the scaled-up radioio
45 BO translation was monitored by pulse-chase radiolabeling and rapid derivatization with a membrane-i
47 onsidered to have non-obvious strategies for radiolabeling and require a more customized approach.
48 DNA cleavage which replaces the traditional radiolabeling and scintillation counting with fluorescen
50 ously developed solution-phase (18)F-"click" radiolabeling and solid-phase radiolabeling using 4-[(18
52 ated to maleimide-desferrioxamine for (89)Zr radiolabeling and subsequent small-animal PET/CT acquisi
53 tions that does not require a chromophore or radiolabeling and thus provides a viable alternative to
55 rescence, western blot analysis, pulse-chase radiolabeling, and biochemical subcellular fractionation
56 This study reports the synthesis, [(123)I]radiolabeling, and biological profile of a new series of
57 atorial chemistry, site-specific solid-phase radiolabeling, and in vivo imaging for the rapid screeni
58 On the basis of site-directed mutagenesis, radiolabeling, and kinetics experiments carried out with
61 njugation, providing a promising alternative radiolabeling approach that maintains the native in vivo
63 ver, we employed shRNA library screening and radiolabeling approaches, as well as in vitro and in viv
68 nt imaging properties but greatly simplified radiolabeling compared with other (68)Ga-PSMA conjugates
71 cted cells was manipulated immediately after radiolabeling de novo-synthesized bacterial proteins.
73 5 degrees C for 2h) of (52)Mn gave excellent radiolabeling efficiencies of 97-100% and 98-100% respec
75 exhibited exceptional cell transfection and radiolabeling efficiencies, providing an overall advanta
77 The described novel protocol improves the radiolabeling efficiency and efficacy of DOTATOC, provid
81 of the techniques, the different methods of radiolabeling erythrocytes, the procedure, useful indica
87 pared from a wzxE-null mutant, and metabolic radiolabeling experiments revealed the accumulation of l
89 conditions were identified and used in eight radiolabeling experiments with 2IT-BAD-Lym-1 and a secon
92 a combination of kinetic studies, selective radiolabeling experiments, and cell viability assays to
98 for quantitative metabolite profiling, i.e., radiolabeling followed by high-performance liquid chroma
99 this laboratory and elsewhere, the method of radiolabeling had an important effect on the biodistribu
100 nnocuous, appending nanoparticles with these radiolabeling handles can have dramatic effects on impor
105 ility has numerous advantages over localized radiolabeling in the preparation of 131I-labeled antibod
106 ter conjugation to a DFO chelator and (89)Zr radiolabeling, in assays including cell uptake, internal
111 tapa-trastuzumab conjugates displayed faster radiolabeling kinetics with more reproducible yields und
113 ations, including insensitivity, reliance on radiolabeling, low throughput and an inability to resolv
114 here an improved MAG3 conjugation and 99mTc radiolabeling method capable of generating high radioche
115 We have characterized an efficient, 1-step radiolabeling method that produces stable, therapeutical
116 high yield, high specific activity, one-step radiolabeling method, high selectivity and favorable kin
117 We present a novel solid-phase based (45)Ti radiolabeling methodology and the implementation of (45)
119 generated a range of innovative chelate-free radiolabeling methods that exploit intrinsic chemical fe
122 tween Hint1 and LysRS, a series of catalytic radiolabeling, mutagenesis, and kinetic experiments was
129 n, and SDS gel analysis revealed 2-fold more radiolabeling of 55-58-kDa 2B15-His by PKCalpha than by
131 nation at RT was successfully applied to the radiolabeling of [(18)F]-2-fluoroethylamines in which th
134 14C]palmitoyl CoA (5 microM) resulted in the radiolabeling of an 80 kDa band demonstrated by SDS-PAGE
136 20.3 min) possesses the unique potential for radiolabeling of any biological, naturally occurring, or
138 The phosite reagent enables the enzymatic radiolabeling of any protein, peptide, or small molecule
139 ortant and versatile building blocks for the radiolabeling of biomolecules via Huisgen cycloaddition
140 allele (as1 allele) results in the exclusive radiolabeling of bona fide substrates of the mutant kina
142 (111)In radiolabeling of DOTA and (64)Cu radiolabeling of CB-TE2A conjugates yielded 370-1,850 an
143 eous sodium chloride (NaCl)-based method for radiolabeling of chelator-modified peptides for molecula
149 ification of the ischemic state via targeted radiolabeling of hypoxia-induced angiogenic receptors is
155 ibroblasts from a human patient, pulse-chase radiolabeling of newly synthesized proteins is used to d
166 development of these modalities through the radiolabeling of somatostatin analogs with various radio
170 The TF-targeted tracer was developed through radiolabeling of the anti-human TF monoclonal antibody (
173 difficult using conventional methods such as radiolabeling of the oligonucleotide or fluorescence con
179 ncountered with previous strategies based on radiolabeling or fluorescence timer proteins, allowed us
181 recurrent prostate cancer by the use of one radiolabeling precursor, which can be radiolabeled eithe
182 c strategy that affords modular synthesis of radiolabeling precursors via a copper-catalyzed 'click'
186 Step 1A of this protocol describes a (64)Cu-radiolabeling procedure for 1,4,8,11-tetraazacyclododeca
190 h impactor stage for all 3 aerosols, and the radiolabeling process itself did not affect their partic
191 ed autophagic flux by two different methods (radiolabeling proteins and a dual-colored LC3 plasmid);
193 time frame (1-4 h) well within that of most radiolabeling protocols, whereas fluorescence analyses u
196 DC018) equipped with both a DOTA chelate for radiolabeling purposes and a fluorophore (IRdye800CW) to
197 cal metal ion chelators that can be used for radiolabeling reactions have residualizing properties in
200 charged nucleic acids (siRNA) and to undergo radiolabeling, respectively, for potential theranostic a
206 of this study was to assess different (18)F radiolabeling strategies of the HER2-specific Affibody m
207 for the coupling of maleimide linkers, and 3 radiolabeling strategies were assessed: silicon-fluoride
209 radiolabel molecules, and select a preferred radiolabeling strategy to progress for automated manufac
211 [(3)H]inositol and [(3)H]dihydrosphingosine radiolabeling studies demonstrated that mutant cells had
221 opulations and, taken together with previous radiolabeling studies, provide strong evidence of in viv
232 ared with their stored test PAS platelets by radiolabeling their stored and control platelets with ei
239 ermine proteoglycan degradation, zymography, radiolabeling to determine chondrocyte biosynthesis, and
241 (18)F-"click" radiolabeling and solid-phase radiolabeling using 4-[(18)F]fluorobenzoic and 2-[(18)F]
243 nsity in whole blood and after isolation and radiolabeling was 25.98 +/- 7.59 and 51.82 +/- 17.44, re
251 ectrospray ionization-mass spectrometry, and radiolabeling was monitored by instant thin-layer chroma
257 To study PIP(2) levels of cells without radiolabeling, we have developed a new method to quantif
260 s exhibited DNA fragmentation in response to radiolabeling whereas only the p53(+/+) cells exhibited
261 nt in the solution phase, and its subsequent radiolabeling with (111)In (T(1/2) = 2.8 d) and (86)Y (T
264 ic acid (DOTA) conjugate of RS7 was used for radiolabeling with (177)Lu-acetate or (88/90)Y-acetate.
266 rolled conjugation and polymerization before radiolabeling with (64)Cu for PET imaging in an apolipop
268 e-1,4,7-triacetic acid at the N terminus for radiolabeling with (64)Cu with a polyethylene glycol spa
270 lator p-SCN-Bn-DFO was conjugated to AMG102, radiolabeling with (89)Zr was performed in high radioche
276 ane (CB-TE2A) was conjugated to c(RGDyK) for radiolabeling with 64Cu (t(1/2), 12.7 h; beta+, 17.4%; E
278 nctionalized biomolecules for the purpose of radiolabeling with 99mTc for gamma detection or single p
281 e human Kv1.1 protein in Sf9 cells, covalent radiolabeling with [(3)H]palmitate, chemical stability s
282 on of selective Triton X-114 solubilization, radiolabeling with [(3)H]palmitic acid, and sucrose dens
283 n elegant new technique for combining iodine radiolabeling with an azamacrocyclic chelator to confer
286 modifications of oligonucleotides to permit radiolabeling with gamma- or positron emitters interfere
291 esent in an ionic environment, was mapped by radiolabeling with N-[3H]ethylmaleimide and identified a
294 This series includes hydrophilic ligands for radiolabeling with the [(99m)Tc(CO)3](+) core (L8-L10),
297 ange reaction, a method that is adaptable to radiolabeling with the positron-emitting isotope fluorin
298 cursors and methods are readily adaptable to radiolabeling with various radiohalides suitable for SPE
300 -methoxyphenyl)iodonium salt and its [(18)F] radiolabeling within a one-step, fully automated and cGM
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