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1 tected lesions (surgery or stereotactic body radiotherapy).
2 monitoring treatment response; and targeting radiotherapy.
3 nssphenoidal surgery, medical therapies, and radiotherapy.
4 during contemporary conformal breast cancer radiotherapy.
5 d chemoradiotherapy than in patients who had radiotherapy.
6 survive standard therapies-chemotherapy and radiotherapy.
7 NSCLC delivering conventionally fractionated radiotherapy.
8 erapy and can limit the duration and dose of radiotherapy.
9 tumors regress at similar rates after plaque radiotherapy.
10 partial-breast]) compared with whole-breast radiotherapy.
11 ving anti-CCR2 antibody treatment to improve radiotherapy.
12 s to their limited sensitivity to chemo- and radiotherapy.
13 targeting enhances the anti-tumor effects of radiotherapy.
14 lopment of more sophisticated strategies for radiotherapy.
15 h to prevent hair loss from chemotherapy and radiotherapy.
16 ansarterial radioembolization, ablation, and radiotherapy.
17 of LC patients received preoperative planned radiotherapy.
18 , using less chemotherapy and more selective radiotherapy.
19 red with standard FU and LV before and after radiotherapy.
20 b combined with neoadjuvant capecitabine and radiotherapy.
21 ; 0.9 MBq/kg) at least 2 wk after completing radiotherapy.
22 tic drugs for synergistically combined chemo-radiotherapy.
23 c therapy, helical tomotherapy, and adaptive radiotherapy.
24 ting personalized radiobiological effects in radiotherapy.
25 stimate the radiobiological effect of clinic radiotherapy.
26 ed surgery, and 16.6% of those who underwent radiotherapy.
27 c strategy to improve the response of GBM to radiotherapy.
28 of the cytotoxic effects of temozolomide and radiotherapy.
29 q22.1-q22.2 amplification fail to respond to radiotherapy.
30 32 patients previously treated with radical radiotherapy.
31 n ions are an increasingly important tool in radiotherapy.
32 tered before, rather than concurrently with, radiotherapy.
33 ned to chemoradiotherapy and 109 patients to radiotherapy.
34 ction could be an alternative to whole-brain radiotherapy.
35 lute long-term risks of modern breast cancer radiotherapy.
36 h are resistant to standard chemotherapy and radiotherapy.
37 d to conventional and 83 to hypofractionated radiotherapy.
38 personalisation and biological adaptation of radiotherapy.
39 as higher in women who had received adjuvant radiotherapy.
40 f excision or, where appropriate, chest-wall radiotherapy.
41 red with those without previous extracranial radiotherapy (0.59 [95% CI 0.36-0.96], p=0.034; median o
43 my (36.2 [95% CI, 30.4-42.0]), external beam radiotherapy (13.9 [95% CI, 6.7-21.2]), and brachytherap
45 azine chemotherapy along with involved-field radiotherapy (25 Gy) for early stage (IA, IB, and IIA) a
46 g patients who received a complete course of radiotherapy (3086 [estimated survival probability, 73.2
47 tabine (825 mg/m(2) orally twice daily) with radiotherapy (50.4 Gy in 1.8 Gy fractions daily, approxi
48 0 mg/m(2) per day on days 1-4 and 29-32) and radiotherapy (50.4 Gy in 28 daily fractions); and also d
49 using the minimisation technique, to receive radiotherapy (59.4 Gy in 33 fractions of 1.8 Gy) alone o
51 objective was to determine whether previous radiotherapy affected progression-free survival, overall
52 arge regional variation exists in the use of radiotherapy after breast-conserving surgery (BCS) for d
53 gn to either palliative chemoradiotherapy or radiotherapy alone for treatment of malignant dysphagia
55 , increase in dysphagia relief compared with radiotherapy alone, with minimal improvement in dysphagi
57 lts of treatment of non-MALT lymphomas using radiotherapy also were good, but they were not as favora
58 t radiotherapy (control), 36 Gy whole-breast radiotherapy and 40 Gy to the partial breast (reduced-do
59 rcinoma (RCC) is polyresistant to chemo- and radiotherapy and biologicals, including TNF-related apop
60 duced skin injury is a common side effect of radiotherapy and can limit the duration and dose of radi
61 icant need to find biomarkers of response to radiotherapy and cetuximab in locally advanced head and
63 which correlates strongly with resistance to radiotherapy and chemotherapy across different tumors.
64 ometastatic patients with the chemotherapy + radiotherapy and chemotherapy alone were 25.2% and 12.7%
65 noma, and contributes to NPC's resistance to radiotherapy and cisplatin by regulating DNA damage and
66 ponse and altered immunity in the setting of radiotherapy and cisplatin treatment and to evaluate the
67 l carcinoma (HNSCC) have better responses to radiotherapy and higher overall survival rates than do p
68 urthermore, the immunosuppressive effects of radiotherapy and STING agonists can be abrogated in huma
69 s designed to show superiority of once-daily radiotherapy and was not powered to show equivalence, th
70 r predicting the absorbed doses in molecular radiotherapy and, thus, the safety and efficacy of a tre
71 Hodgkin lymphoma (HL) survivors treated with radiotherapy and/or chemotherapy are known to have incre
72 one local treatment (surgery with or without radiotherapy) and had completed 4-6 years of adjuvant en
73 ) after radical prostatectomy, external beam radiotherapy, and brachytherapy vs active surveillance.
77 ancer cells to conventional chemotherapy and radiotherapy, and the potential to overcome tumor microe
78 med for both reduced-dose and partial-breast radiotherapy, and was confirmed by the test against the
79 eatment type (radical prostatectomy, radical radiotherapy, androgen deprivation therapy, and watchful
81 RT dosage to improve survival.Significance: Radiotherapy appears to influence systemic IDO activity
83 logic benefit, use of postoperative adjuvant radiotherapy (aRT) in patients with prostate cancer is s
84 inical adverse effect for patients receiving radiotherapy as part of the standard course of treatment
85 ncology modalities but also chemotherapy and radiotherapy as standards of care in the oncology clinic
86 le if patients received chemoradiotherapy or radiotherapy as the main treatment, reported LNP proport
87 ; 95% CI, 0.59-0.81; P < .001) and receiving radiotherapy at a different hospital than the one where
89 A total of 122 patients (40.9%) responded to radiotherapy at day 10 and 116 patients (38.9%) at day 4
90 e for muscle-invasive bladder cancer (MIBC), radiotherapy-based, bladder-sparing trimodal therapy (TM
96 tomy followed by multiagent chemotherapy and radiotherapy; cohort one included patients with R0 resec
97 gnificantly worse with altered fractionation radiotherapy compared with concomitant chemoradiotherapy
98 feriority of partial-breast and reduced-dose radiotherapy compared with the standard whole-breast rad
99 atients who previously received extracranial radiotherapy compared with those without previous extrac
100 atients who previously received extracranial radiotherapy compared with those without previous extrac
103 signed (1:1:1) to receive 40 Gy whole-breast radiotherapy (control), 36 Gy whole-breast radiotherapy
104 diotherapy (SCRT) compared with conventional radiotherapy (ConvRT) evaluating clinically meaningful e
106 fter brain metastasis resection, whole brain radiotherapy decreases local recurrence, but might cause
107 here is a substantial opportunity to improve radiotherapy delivery beyond just technological and anat
111 a multiagent regimen of ECF before and after radiotherapy does not improve survival compared with sta
114 nter phase II study investigated a selective radiotherapy dose increase to tumor areas with significa
122 eatment in vivo significantly enhances chemo-radiotherapy efficacy and improves survival of rats and
125 g-term findings showed that hypofractionated radiotherapy failed the intent of either reducing physic
127 ols), who underwent contemporary (1998-2013) radiotherapy for breast cancer with computed tomography-
128 xamine whether regional practice patterns of radiotherapy for DCIS affect the use of mastectomy in th
129 Although patients who do not receive initial radiotherapy for DCIS are candidates for subsequent BCS
132 e benign or low-grade brain tumors requiring radiotherapy for long-term tumor control, SCRT compared
133 toxicity in patients who previously received radiotherapy for non-small-cell lung cancer (NSCLC) befo
135 fficacy when used with concurrent definitive radiotherapy for patients with stage III unresectable NS
136 l wound healing after eAPR with preoperative radiotherapy for rectal cancer was not improved when usi
138 ) of 97 patients had previously received any radiotherapy for the treatment of NSCLC before the first
139 adiotherapy group and 38 (35%, 26-44) in the radiotherapy group obtained dysphagia relief (difference
141 Three (13%) patients with previous thoracic radiotherapy had treatment-related pulmonary toxicity co
143 r radiation sensitization, and external beam radiotherapy has emerged as a valid treatment option.
145 Despite its common use in cancer treatment, radiotherapy has not yet entered the era of precision me
146 radicals, including photodynamic therapy and radiotherapy, have emerged as promising treatments in th
147 diotherapy than in patients without previous radiotherapy (hazard ratio [HR] 0.56 [95% CI 0.34-0.91],
148 red with those without previous extracranial radiotherapy (HR 0.50 [0.30-0.84], p=0.0084; median prog
149 diotherapy than in patients without previous radiotherapy (HR 0.58 [95% CI 0.36-0.94], p=0.026; media
150 g performed on cancer tissues prior to chemo/radiotherapy identified one hypermethylated CpG site (Cp
151 (VMAT), and fixed-field intensity-modulated radiotherapy (IMRT) for NSCLC delivering conventionally
154 comparing conventional and hypofractionated radiotherapy in high-risk, organ-confined prostate cance
156 ur data suggest that previous treatment with radiotherapy in patients with advanced NSCLC results in
157 ermine whether PET can obviate consolidation radiotherapy in patients with diffuse large B-cell lymph
159 ADT) (86.0%, n = 308) alone or combined with radiotherapy in prostate cancer IS (80.8%, n = 517).
161 rapy compared with the standard whole-breast radiotherapy in terms of local relapse in a cohort of pa
164 rocognitive dysfunction include avoidance of radiotherapy in young children and reduction of the radi
165 nation radiotherapy vs altered fractionation radiotherapy) included 33 trials and 11 423 patients.
166 effects after reduced-dose or partial-breast radiotherapy, including two patient domains achieving st
167 th BCL-2 inhibition, as DNA damage caused by radiotherapy increases the activity of pro-apoptotic BCL
168 tment type (radical prostatectomy or radical radiotherapy), increasing comorbidity does not seem to s
171 cedure, with stratification by country, age, radiotherapy intent, nodal status, and oestrogen recepto
174 ck (MARCH) showed that altered fractionation radiotherapy is associated with improved overall and pro
176 city-induced hair loss from chemotherapy and radiotherapy is often encountered in cancer treatment, a
178 rst version of MARCH, that hyperfractionated radiotherapy is, along with concomitant chemoradiotherap
179 the use of upfront EGFR-TKI, and deferral of radiotherapy, is associated with inferior OS in patients
180 d cancer cell's response to chemotherapy and radiotherapy, little is known about the role of histone
184 m that Cu-Cy nanoparticles may improve X-ray radiotherapy on cancer treatment and X-ray activated Cu-
185 nce, smoking can determine the net effect of radiotherapy on mortality, but smoking cessation substan
188 ow or HER2-negative breast cancers following radiotherapy or endocrine therapy, and this drives tumor
190 enetoclax combined with either external beam radiotherapy or radioimmunotherapy (RIT), which joins th
193 nsurance status was predictive of completing radiotherapy (OR, 1.60; 95% CI, 1.16-2.21; P = .004).
194 nhance the efficacy of cancer immunotherapy, radiotherapy, or 'immunogenic' chemotherapy by leveragin
195 ontrol group, investigating hypofractionated radiotherapy, or including mostly nasopharyngeal carcino
197 ded management plans for treatment (surgery, radiotherapy, or systemic therapy) within 90 d for lung
199 explain the superiority of hyperfractionated radiotherapy over other altered fractionation radiothera
200 sone for the prophylaxis of pain flare after radiotherapy, patients were accrued from 23 Canadian cen
201 tinal toxicity in patients undergoing pelvic radiotherapy.Patients were randomly assigned to low-fibe
204 patients with nonmetastatic disease with no radiotherapy planned and for patients with metastatic di
211 photodynamic therapy, photothermal therapy, radiotherapy, protected delivery of bioactive moieties,
214 adiotherapy over other altered fractionation radiotherapy regimens and to assess the benefit of alter
215 ever, overall survival in patients receiving radiotherapy remained very good, with the 5-year and 10-
216 Clinical Question: Is up-front whole-brain radiotherapy required to treat multiple brain metastases
217 ts may alter MDM2 expression and thus affect radiotherapy response and prognosis of squamous cell car
218 ce to follow a high-fiber diet during pelvic radiotherapy resulted in reduced gastrointestinal toxici
220 Purpose To evaluate the effect of adjuvant radiotherapy (RT) after breast conservation surgery in d
227 kelihood of a local relapse, the addition of radiotherapy (RT) to limb-sparing surgery may result in
228 r receptor (EGFR) monoclonal antibodies with radiotherapy (RT) to standard chemoradiotherapy in locor
229 ed patients with stage III disease receiving radiotherapy (RT) with carboplatin-paclitaxel or cisplat
231 uideline on treatment with stereotactic body radiotherapy (SBRT) for patients with early-stage non-sm
232 tage small-cell lung cancer, but the optimal radiotherapy schedule and dose remains controversial.
233 zed clinical trial of stereotactic conformal radiotherapy (SCRT) compared with conventional radiother
234 nd adjuvant temozolomide to hypofractionated radiotherapy seems to be safe and efficacious without im
235 valence, the implication is that twice-daily radiotherapy should continue to be considered the standa
236 breast-conserving surgery with whole-breast radiotherapy should not undergo ALND (in most cases).
239 a-camera with (90)Y after selective internal radiotherapy (SIRT) may allow for verification of treatm
240 lineations for prostate cancer (PCa) salvage radiotherapy (SRT) after radical prostatectomy are usual
241 ain management-analgesia, adjunct therapies, radiotherapy, surgery, systemic anticancer therapy, and
242 Cs (including those recurrent after surgery, radiotherapy, systemic chemotherapy, or topical chemothe
246 ential role of modern imaging and innovative radiotherapy techniques in minimisation of neurocognitiv
247 lication of stereotactic and other conformal radiotherapy techniques in treating brain tumors is larg
249 nger in patients who previously received any radiotherapy than in patients without previous radiother
250 nger in patients who previously received any radiotherapy than in patients without previous radiother
255 vidence demonstrates that adding neoadjuvant radiotherapy to surgery offers better local control in t
256 imiting radiation dermatitis associated with radiotherapy, to cutaneous radiation syndrome, a frequen
258 were also strongly predictive of outcome in radiotherapy-treated patients across multiple independen
261 should be done relative to PMRT and whether radiotherapy treatment should be directed towards the ti
262 occurred more often in patients with radical radiotherapy treatment, positive (68)Ga-PSMA scan result
263 gnosis, approaches to surgery, chemotherapy, radiotherapy, treatment of recurrence, palliative care,
264 evious study on the efficacy of the thoracic radiotherapy (TRT) in oligometastatic or polymetastatic
265 cally advanced cSCC who declined surgery and radiotherapy underwent treatment with pembrolizumab, an
266 sis, prior chemotherapy, prior external-beam radiotherapy, uptake on the [(111)In-DTPA(0)]octreotide
268 Residence in an HSA characterized by greater radiotherapy use for DCIS increased the likelihood of re
270 pread use of techniques such as image-guided radiotherapy, volumetric modulated arc therapy, helical
271 Comparison 1 (conventional fractionation radiotherapy vs altered fractionation radiotherapy) incl
272 among patients not receiving previous pelvic radiotherapy was 24.5 months versus 16.8 months (0.64 [0
274 (nonmetastatic); prostate (+/- pelvic node) radiotherapy was encouraged for men without metastases.
277 change in score between the start and end of radiotherapy was smaller in the high-fiber group (mean +
279 Stereotactic radiosurgery (SRS), whole-brain radiotherapy (WBRT), and epidermal growth factor recepto
283 lue predicts for high therapeutic effect for radiotherapy; which we postulate would relate to clinica
284 intestinal tract from deleterious effects of radiotherapy will significantly improve patient quality
285 To investigate QOL at days 10 and 42 after radiotherapy with a bone metastases-specific QOL tool.
287 Recommendations Partial-brain fractionated radiotherapy with concurrent and adjuvant temozolomide i
288 mozolomide given on days 1-5); or to receive radiotherapy with concurrent temozolomide 75 mg/m(2) per
289 days apart, followed by intensity-modulated radiotherapy with daily image guidance plus 30 mg/m(2) p
290 ain reduction and better QOL at day 10 after radiotherapy with further improvements in QOL at day 42
293 HNSCC from a phase 3 trial of cisplatin plus radiotherapy with or without cetuximab (NRG Oncology RTO
294 Twenty-five studies reported results using radiotherapy with or without chemotherapy or surgery.
298 se 2 dose of veliparib plus capecitabine and radiotherapy, with an exposure-adjusted continual reasse
299 ion-free survival compared with conventional radiotherapy, with hyperfractionated radiotherapy showin
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