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1 s ((18)F-FDG, (99m)Tc-rhAnnexin V-128, or no radiotracer).
2 h-quality second-generation TSPO-binding PET radiotracer.
3 F to a carbon in the organic backbone of the radiotracer.
4 ramycin demonstrated specific binding of the radiotracer.
5 FSPG images to evaluate the kinetics of this radiotracer.
6 d binding in the dorsal striatum with either radiotracer.
7 ther studied to evaluate it as a PET imaging radiotracer.
8 6.2 d (range, 0-13 d) after injection of the radiotracer.
9 y or late time points after injection of the radiotracer.
10 the sand patties as shown with a (35)SO4(2-) radiotracer.
11 limited by local retention of cell-effluxed radiotracer.
12 essed using (99m)Tc-linear duramycin control radiotracer.
13 ormed to assess beta-cell selectivity of the radiotracer.
14 a rise in hypoxia-mediated entrapment of the radiotracer.
15 escribed herein was to identify such a novel radiotracer.
16 nts relative to healthy controls with 2 TSPO radiotracers.
17 n CT and low uptake in the lung for both PET radiotracers.
18 l molecules to generate disease specific PET radiotracers.
19 nto the development of new TSPO-specific PET radiotracers.
20 lar in magnitude to many other (18)F-labeled radiotracers.
21 d solutions of the most common PET and SPECT radiotracers.
22 ance of MPI with low-dose and ultra-low-dose radiotracers.
23 esion confirm their potential as in vivo PET-radiotracers.
24 ore, these studies have only used antagonist radiotracers.
25 2.5-fold increase over baseline for both PET radiotracers.
26 , a known characteristic for exendin-4-based radiotracers.
27 e chiral (18)F synthons for the synthesis of radiotracers.
28 after injection in comparison to the other 2 radiotracers.
29 erformed to assess the bioequivalence of all radiotracers.
30 onvenient synthon for labeling potential PET radiotracers.
31 milar kinetic and binding profiles for the 2 radiotracers.
32 ating the in vivo behavior of antibody-based radiotracers.
33 essibility and short half-lives of perfusion radiotracers.
34 nt in vitro studies suggested that the novel radiotracer 1-(2-(18)F-fluoroethyl)-l-tryptophan ((18)F-
35 umor uptake of fructose metabolism-targeting radiotracers 1-[(18)F]FDF, 6-[(18)F]FDF, and 1-[(18)F]FD
36 -labeled prosthetic as a potential (18)F-PET radiotracer (1) or a fluorescence probe (2) for internal
37 re compared with (18)F-FBA -labeled A20FMDV2 radiotracers (1- 3) bearing either no PEG or different P
40 nthesis and characterization of the SV2A PET radiotracer (11)C-UCB-J ((R)-1-((3-((11)C-methyl-(11)C)p
41 sis and cerebral glucose metabolism with the radiotracers (11)C-Pittsburgh compound-B (PIB), (11)C-de
42 bility in the VS with the use of the agonist radiotracer [(11)C]-(+)-PHNO (n = 26) and the antagonist
45 PET imaging using the second-generation TSPO radiotracer [(11)C]DPA-713 revealed a strong trend towar
46 ) and positron emission tomography using the radiotracer [(11)C]FLB457 before and after amphetamine t
48 D2/3 agonist positron emission tomography radiotracer [(11)C]N-propyl-norapomorphine ([(11)C]NPA)
49 the cannabinoid receptor-1 (CB1R) selective radiotracer [(11)C]OMAR on the high resolution research
50 ography and the selective mu-opioid and D2/3 radiotracers [(11)C]carfentanil and [(11)C]raclopride ha
51 administered 1 min prior to injection of the radiotracer, [(11)C]GR103545 binding potential (BPND) wa
52 aphy and the micro-opioid receptor-selective radiotracer [11C]carfentanil after each 1-week inactive
53 with the positron emission tomography (PET) radiotracer [11C]PBR28, which binds to translocator prot
54 this problem by identifying and describing a radiotracer, [11C]GV1-57, that appears to specifically l
56 uptake were observed when the CD20-specific radiotracers (125)I-Fab-ABD and (125)I-Fab-PAS200 were a
57 ivo The pharmacologic properties of the PARP radiotracer [(125)I] KX1: was characterized in multiple
58 ate the role of the synthetic amino acid PET radiotracer (18)F-fluciclovine in modifying the defined
60 erwent positron emission tomography with the radiotracer [(18)F]fluoro-l-DOPA to quantify striatal pr
61 s to evaluate if the recently introduced PET radiotracer [(18)F]tetrafluoroborate ([(18)F]BF4(-)) is
63 btype) availability using PET imaging of the radiotracer 2-(18)F-fluoro-3-(2(S)-azetidinylmethoxy)pyr
65 ting (T87) tumor phenotype using 2 different radiotracers, 2 different image reconstruction algorithm
68 lts for the novel estrogen receptor (ER) PET radiotracer 4-fluoro-11beta-methoxy-16alpha-(18)F-fluoro
70 d adjuvant arthritis mice model, whether the radiotracer (99m)Tc-N-(triethylammonium)-3-propyl-[15]an
71 n emission computed tomography imaging and a radiotracer ((99m)Tc-labeled rhesus immunoglobulin G1 an
74 t of intraoperative detectors that can image radiotracers accumulated within tumors, thus facilitatin
75 with the amount of time required for kidney radiotracer activity to fall by 50% after intravenous ad
78 went PET/CT with (68)Ga-DOTA-E-[c(RGDfK)](2) radiotracer and blood-sample tests to quantify angiogene
79 we developed a (18)F-labeled small molecule radiotracer and investigated its in vivo pharmacokinetic
81 obtained using PET/CT guidance contain bound radiotracer and therefore provide information about trac
82 tion, should enable their theranostic use as radiotracers and as photothermal probes in tumor ablatio
84 ith [(11)C]FLB457, a dopamine D2/D3 receptor radiotracer, and positron emission tomography (PET).
86 gs; in 32 (30.8%), on the findings with both radiotracers; and in 50 (48.1%), on the (68)Ga-DOTATATE
87 ptake of the synthetic amino acid analog PET radiotracer anti-3-(18)F-FACBC ((18)F-fluciclovine) in b
89 ation dynamics in lotic food webs, we used a radiotracer approach to characterize accumulation in per
91 are many, positron emission tomography (PET) radiotracers are still available only as research tools.
93 includes physiologic biodistribution of the radiotracer, as well as conditions that engender false-p
94 ular disorders by use of a validated ex-vivo radiotracer assay that involved incubation of cholestero
95 mino acid fluxes via VRAC were quantified by radiotracer assays in cells challenged with hypoosmotic
101 ters is based on pharmacokinetic modeling of radiotracer biodistribution, which requires the blood in
103 al relative to nondisplaceable uptake of the radiotracer, BPnd) (in 31 methamphetamine users and 37 c
104 anoparticle constructs have been utilized as radiotracers, but irrespective of the particle class, ra
105 T with selective adenosine 2A receptor (A2A) radiotracers can be used to study a variety of neurodege
106 ion tomography with the dopamine D2 receptor radiotracer carbon 11-labeled FLB457 before and after am
107 using the positron emission tomographic D2/3 radiotracer carbon 11-labeled FLB457 in combination with
109 mulations showed a limited impact of CBF and radiotracer clearance changes on multilinear reference t
110 re performed to assess the effect of CBF and radiotracer clearance changes on SUVRs and noninvasive k
111 ond, to assess the impact of CBF changes and radiotracer clearance on SUVRs and noninvasive kinetic m
113 te analysis using the combined data from all radiotracers clearly separated the different groups alon
114 positron emission tomography (PET) using D2R radiotracers combined with psychostimulant challenge.
116 contiguous acquisition steps, corrected for radiotracer decay and injected dose, and fitted to a bic
119 (18)F-DCFBC, a small-molecule PSMA-targeted radiotracer, detected more lesions than CIM and promises
128 model, significantly longer retention of the radiotracer during (18)F-FDG lymphography was seen in me
130 ability to bind cell surface PSMA, and both radiotracers exhibited selective uptake into PSMA-positi
134 bring data in favor of the (99m)Tc-NTP 15-5 radiotracer for assessing, in vivo, cartilage remodeling
138 (89)Zr-DFO-AC-10 is a promising CD30-imaging radiotracer for clinical translation in patients with va
139 mycin holds promise as a noninvasive imaging radiotracer for early treatment evaluation in the clinic
140 r study to target VX2 tumor and serve as the radiotracer for follow-up single-photon emission compute
141 We have developed a metabolically activated radiotracer for functional imaging of P-gp/BCRP activity
143 ivo evaluation of (18)F-MNI-444, a novel PET radiotracer for imaging A2A, in healthy human subjects.
146 develop and evaluate preclinically a (68)Ga radiotracer for imaging PSMA expression that could be ra
147 acterial accumulation, make it an attractive radiotracer for infection imaging in clinical practice.
150 use as a positron emission tomography (PET) radiotracer for noninvasive detection of lung inflammati
155 PET)/computed tomography (CT) is a promising radiotracer for quantitative assessment of bone metastas
157 8)F-LY2459989 appears to be an excellent PET radiotracer for the imaging and quantification of the KO
161 This process has potential for preparing new radiotracers for molecular imaging with positron emissio
165 g because of the use of this radionuclide in radiotracers for positron emission tomography (PET).
167 ed with radioisotopes are being developed as radiotracers for the detection and phenotyping of diseas
168 their development and application as [(18)F]radiotracers for the study of S1PR biodistribution and i
169 11)C-elacridar and (11)C-tariquidar are safe radiotracers, for which an injected activity of 400 MBq
171 e kinetic data showed rapid clearance of the radiotracer from the blood pool and most organs, except
174 application of these second-generation TSPO radiotracers has revealed additional problems, including
176 89 as the first (18)F-labeled KOR antagonist radiotracer in nonhuman primates and its comparison with
179 nalization and the resulting accumulation of radiotracers in cells is necessary for efficient tumor t
182 and BxPC-3 (alphavbeta6+), we evaluated the radiotracers in vitro (serum stability; cell binding and
184 red in biodistribution studies 285 min after radiotracer injection (percentage injected dose per gram
188 pheres were injected simultaneously with the radiotracer injections at rest and stress to measure blo
189 em that converts the beta radiation from the radiotracer into photons close to the decay origin throu
191 fore, we conclude that this first antagonist radiotracer is highly useful for PET studies of KOR.
193 PET/CT-guided biopsy using (89)Zr-labeled radiotracers is safe and effective without tracer reinje
194 hese studies, performed with D2/3 antagonist radiotracers, is the failure to provide information abou
195 rived compounds, including metabolism of the radiotracer itself, led to the development of synthetic
196 ted from dynamic acquisitions and reflecting radiotracer kinetics may provide additional information.
197 success of PC treatment with PSMA inhibitor radiotracers leads to several questions from the basic r
199 ifficulties with preparing suitably labelled radiotracers limit its scientific and diagnostic applica
200 ng both [(11)C]DASB and [(18)F]MPPF, two PET radiotracers, marking the serotonin transporter and the
202 after diagnostic PET/CT using (89)Zr-labeled radiotracers (mean dose, 180 MBq; range, 126-189 MBq) ta
203 sing tetramethylammonium, as well as earlier radiotracer methods, have shown that the extracellular s
204 tumor imaging features of this last class of radiotracers mirror the upregulation of transmembrane am
205 and validating targeted adrenoceptor-binding radiotracers, namely the heavily weighted flow dependenc
207 We used (123)I-iodobenzovesamicol, a SPECT radiotracer of the vesicular acetylcholine transporter,
208 and ischemia, rate-pressure product, type of radiotracer or stress agent used, and revascularization
210 e feasibility of within-suite (89)Zr-labeled radiotracer PET/CT-guided biopsy performed without reinj
211 xisting fluorine-18-labeled amino acid-based radiotracers predominantly visualize amino acid transpor
212 -444, compared with previously developed A2A radiotracers, provide the opportunity to foster global u
216 l maximum signal intensity (MSI), MSI value, radiotracer retention index (RI, myocardial activity/blo
217 we hypothesise will result in minimal local radiotracer reuptake and allow a more accurate estimatio
225 with naturally occurring amino acid-derived radiotracers, such as l-(11)C-methionine and l-1-(11)C-5
226 attenuation correction (AC), and inaccurate radiotracer SUV estimation can limit future PET/MR clini
233 compound [(125)I] KX1: as a PARP-1-selective radiotracer that can accurately measure PARP-1 expressio
235 8)F-fluciclovine) is a leucine analog PET/CT radiotracer that depicts amino acid transport into cells
236 cid ((18)F-fluciclovine) is a leucine analog radiotracer that depicts amino acid transport into cells
237 d that (125)I-iodo-DPA-713, a small-molecule radiotracer that specifically targets macrophages, could
238 steine ((18)F-DCFBC), a low-molecular-weight radiotracer that targets the prostate-specific membrane
240 ions to study the brain has been the lack of radiotracers that can identify and measure specific type
241 e potential to become a prototype for future radiotracers that can identify other neuronal cell types
242 d pharmacokinetics of the antibody-based PET radiotracers that correlated well with the behavior obse
243 nvolved in cognition and behaviors, by using radiotracers that detect relevant biological reactions.
244 itron emission tomography (PET) imaging with radiotracers that target translocator protein 18 kDa (TS
245 estimated that by administering 3 mBq/kg of radiotracer, the time needed to detect a 0.1-mL remnant
246 that by administering a 3 MBq/kg activity of radiotracer, the time needed to detect a 0.1-mL remnant
250 ositron emission tomography may be the first radiotracer to reflect the loss of pigmented neurons in
252 : verified in vitro results, validating PARP radiotracers to define PARP-1 enzyme expression as an in
253 locator protein positron emission tomography radiotracer together with amyloid imaging using Pittsbur
259 rtery, and assessed the relationship between radiotracer uptake and plaque phenotype or predicted car
261 administration of ICM led to a reduction in radiotracer uptake by the thyroid, accompanied by a dram
262 bbed droplet radiofluidics, that can measure radiotracer uptake for single cells encapsulated into an
263 the first time, the detection of [(18)F]FDG radiotracer uptake in single cells through fluorescence
266 combined findings of grade 2 or 3 myocardial radiotracer uptake on bone scintigraphy and the absence
267 have nonamyloid cardiomyopathies, myocardial radiotracer uptake on bone scintigraphy was >99% sensiti
273 cause inaccuracies in the quantification of radiotracer uptake, which negatively affects PET-guided
278 de strong preclinical evidence that this new radiotracer warrants further studies that may lead to a
281 )C]flumazenil, a benzodiazepine-specific PET radiotracer, was measured before and after administratio
282 th the recent development of in vivo tau PET radiotracers, we show that Abeta and tau are associated
283 tumor targeting and pharmacokinetics of the radiotracers were also evaluated in HCC827, H1975, H358
288 hymidine ((18)F-FLT); a clinically available radiotracer which we hypothesise will result in minimal
289 d to the development of synthetic amino acid radiotracers, which are not metabolized and therefore mo
292 this characteristic can be exploited when a radiotracer with a long half-life, such as 90Y, is used.
293 - or (177)Lu-labeled NeoBOMB1 is a promising radiotracer with excellent tumor uptake and favorable ph
294 ated analogues aiming for an [(18)F]-labeled radiotracer with improved CB2 binding affinity and selec
296 hat allow the use of relatively low doses of radiotracers with high sensitivity for even small breast
297 d concentration of most common PET and SPECT radiotracers with high temporal resolution in small bloo
298 25 novel radioligands that aims to identify radiotracers with optimal pharmacokinetic and dosimetric
299 conducted, with the eventual replacement of radiotracers with stable isotopically labeled ones, even
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