ライフサイエンスコーパス: raise question about

1 L exposure to CpG oligodeoxynucleotide (ODN) raised questions about a central role for TLR-9.

2 that are depleted of repeat sequences, which raises questions about a role for mammalian Piwi's in tr

3 arger-scale, multicenter studies of ACF have raised questions about ACF.

4 erious to cycling cells than ATR inhibition, raising questions about ATR and Chk1 functions in the ab

5 f As(II,III) for Fe in our synthetic samples raises questions about both the possible occurrence and

6 This raises questions about causality and possible carbonaceo

7 on of biosynthetic enzymes across genera but raises questions about conserved biosynthetic mechanisms

8 effect across many different service systems raises questions about coordination of services and sect

9 Our study raises questions about decision regret in patients who a

10 eplicate the results of the initial studies, raising questions about differences in the behaviors of

11 Increasing use of genetic testing raises questions about disclosing secondary findings, in

12 ransmitter release at many central synapses, raising questions about effects of FHM1 mutations on neu

13 moking appears limited to Hispanic children, raising questions about ethnic differences in tobacco-re

14 ed to investigate aspects of fungal biology, raising questions about evolution and specialization wit

15 volved multiple times in a range of animals, raising questions about factors that drive such extreme

16 Indeed, most lncRNAs are not conserved, raising questions about function.

17 Differences in incidence by sex and race raise questions about genetic and environmental influenc

18 Taken together, these findings raise questions about how best National Institutes of He

19 These data raise questions about how long allergen tolerance is mai

20 logical roles of hydroxymethylation serve to raise questions about how this epigenetic modification e

21 However, they raise questions about how to best address potential thre

22 te mesodermal derivatives to the bauplan has raised questions about how this apparent gain in potenti

23 This knowledge therefore raises questions about how asthma affects fertility path

24 s roles in both cancer and Golgi trafficking raises questions about how GOLPH3 and the Golgi contribu

25 This raises questions about how plants manage to translate st

26 The study raises questions about how policy-makers deal with the c

27 New research raises questions about how such domains are defined with

28 This raises questions about how the time course of endocytosi

29 rils of chimerism, including cheating, which raises questions about how the victims survive in nature

30 fated GlcNH(3)(+)-disaccharides in kidney HS raises questions about how these sequences are generated

31 lantation and pathological metastasis, which raises questions about how this process is controlled.

32 Kerberos may be much darker, raising questions about how a heterogeneous satellite sy

33 However, iRhom2(-/-) mice appear normal, raising questions about how ADAM17 is regulated in other

34 dividual motors are not robustly processive, raising questions about how dynein-associated cargoes ca

35 biome and less prevalent in the healthy gut, raising questions about how fusobacteria localize to CRC

36 independently of host-specific interactions, raising questions about how mutualism shapes the realise

37 of the only known vertebrate sweet receptor, raising questions about how specialized nectar feeders s

38 ntrol and spontaneous imaginative processes, raising questions about how these regions interact to su

39 towards less intensive alternative regimens raises questions about identifying patients in whom an a

40 results clarify the H. habilis hypodigm, but raise questions about its phylogenetic relationships.

41 use paraquat is di-cationic in plasma, which raises questions about its ability to cross the blood br

42 nt in humans that localizes to the membrane, raises questions about its function in neddylation.

43 sformation, the complexity of the D'' region raises questions about its geophysical significance.

44 of a unique TCR chain in marsupials, TCRmu, raises questions about its possible role in early develo

45 evance of miR-29b in aortic disease but also raises questions about its specific role.

46 DSM criteria for major depressive disorder, raising questions about its clinical significance.

47 y seen in arbovirus-infected mosquito cells, raising questions about its importance as an antiviral d

48 since been shown to be a common phenomenon, raising questions about its role in DNA damage induced b

49 vergence relative to the remaining variants, raising questions about its taxonomic status.

50 ty in families of people with schizophrenia, raising questions about its utility in genetic studies.

51 in or function compared with sham treatment, raising questions about its value for these patients.

52 The apparent strength of the cohort trends raises questions about life-course inequalities in the s

53 ion, particularly in obese and older donors, raises questions about limitations of the renal adaptive

54 onstraints on water resources are appearing, raising questions about limits to water availability.

55 prisingly few pathways signal between cells, raising questions about mechanisms for tissue-specific r

56 separase lacks microtubule-binding activity, raising questions about mechanisms underlying this pheno

57 therapy (NAC) for operable breast cancer has raised questions about optimal local therapy for the axi

58 otic proteins, CenH3's are rapidly evolving, raising questions about orthology and conservation of fu

59 Results raised questions about our current understanding of the

60 This raises questions about our fundamental understanding of

61 The study raised questions about persistence of diseases through i

62 nce in different diseases and in health have raised questions about potential pathogenic mechanism me

63 Research on geologic carbon sequestration raises questions about potential impacts of subsurface m

64 ARs appear to be linked to innate responses, raising questions about regulatory mechanisms that might

65 n-selective cells but lack orientation maps, raising questions about relationships of horizontal conn

66 ingle organism and from different organisms, raising questions about sequence-specific effects on RNA

67 This finding raises questions about signal processing within the reti

68 These findings raise questions about skills transfer from simulation tr

69 These observations raise questions about SNARE control in exocytosis and en

70 d HslV within these bacterial genomes, which raises questions about specialized protein degradation s

71 of molecules in Phase III for poor efficacy raise questions about target identification and validati

72 new level of interspecies communication, and raise questions about the ability of parasites to recogn

73 ogical response to influenza vaccination and raise questions about the added benefits of using a quad

74 terion C symptoms for preschool children and raise questions about the appropriateness of this thresh

75 Our results raise questions about the assumed social-information ben

76 hallenges for spacefaring civilizations, and raise questions about the assumption of a thermoregulato

77 nhanced prospects for natural gas production raise questions about the balance of impacts on air qual

78 astroenteritis outbreaks, these observations raise questions about the biological properties of the v

79 inconsistent with long-term persistence and raise questions about the capsule's role in pneumococcal

80 Concerns about cardiovascular safety raise questions about the chronic use of nonsteroidal an

81 They raise questions about the concept of restricted antigen

82 The results raise questions about the continued use of traditional l

83 st degradation of organic carbon in soil and raise questions about the current prediction of terrestr

84 Their results raise questions about the developmental formation of thi

85 These findings raise questions about the effect of antifungal agents an

86 ntrolled trials, published in 2015 and 2016, raise questions about the effectiveness of pressure ther

87 These results raise questions about the effectiveness of punishment fo

88 These findings also raise questions about the efficacy of CD8(+) T cell-base

89 The results of the present study raise questions about the focus of risk assessment schem

90 elayed rectifier (FDR) potassium current and raise questions about the function of this current.

91 These data raise questions about the general nature of the relation

92 These findings raise questions about the implications of notifying pati

93 tat6 in airway epithelium induces murine AHR raise questions about the importance of direct IL-4R eff

94 cell wall pores in plant uptake of MNMs, and raise questions about the importance of plant species to

95 of sodium channel blockers in immune cells, raise questions about the long-term effects of sodium ch

96 s linked to the consumption of fresh produce raise questions about the mechanisms by which human path

97 These findings raise questions about the origins of differences among S

98 These findings raise questions about the physical nature of the strong

99 These findings raise questions about the potential role of HRV in the a

100 These findings raise questions about the potential role of Itk and Rlk

101 These results raise questions about the prevalence of HPV infection in

102 the biogenesis and regulation of miRNAs, and raise questions about the processes and molecular mechan

103 ssible and physiological ADAMTS13 assays may raise questions about the rationale for and value of pla

104 These results raise questions about the reasons for the ubiquity of Me

105 with proximal dendrites of granule cells and raise questions about the recurrent excitation hypothesi

106 The results raise questions about the relative effectiveness of inte

107 virus (AIV) H9 infection in frugivorous bats raise questions about the role of bats in IAV epidemiolo

108 Our findings raise questions about the role of isolated 3' UTR sequen

109 Taken together, these data raise questions about the role of PKCepsilon in driving

110 Most importantly, these results raise questions about the role of the organizer grafts a

111 n of delay eyeblink conditioning and MWM and raise questions about the role, if any, of cerebellar co

112 Surprisingly, these results raise questions about the rules for renal filtration, gi

113 These observations raise questions about the sources of the B cells that re

114 e of the overall transplant waiting list and raise questions about the stewardship of scarce resource

115 , however, patterns of amino acid usage that raise questions about the strength (and possibly the uni

116 These findings raise questions about the types of learning environments

117 These findings raise questions about the use of critical care at the en

118 These findings raise questions about the usefulness of pretreatment PSR

119 Through these comparisons, the authors raise questions about the validity of self-reported fami

120 These findings raise questions about the value of PET-CT scans in this

121 Research has raised questions about the ability of clinicians to make

122 r waves and Ca2+ sparks in perinuclear area) raised questions about the classical views of RyR2 distr

123 rus transmission, particularly in India, has raised questions about the degree of mucosal immunity in

124 Renewed interest in stem cells has raised questions about the effect de-differentiation has

125 lts of blinded versus open trial designs has raised questions about the effectiveness of water qualit

126 e spliceosome functions in 3' end processing raised questions about the evolutionary origin and conse

127 inding, and crystallographic structures have raised questions about the extent to which generalizatio

128 tructural analyses of ARFs and Aux/IAAs have raised questions about the functional complexes driving

129 These observations have raised questions about the functional significance of th

130 sonance imaging for viability assessment has raised questions about the future role of positron emiss

131 een the CSS progenitor strains in that study raised questions about the impact of genetic divergence:

132 an M. genitalium-and these tiny genomes have raised questions about the limits of genome reduction an

133 igh-level Ag-specific Ab responses, but also raised questions about the mechanisms responsible for su

134 i Migratory Bird Flyway in Wisconsin, U.S.A. raised questions about the natural history of these rare

135 ee as a vehicle for added fat and sugar have raised questions about the net impact of coffee on healt

136 h morphometric and metagenomic analyses have raised questions about the prevalence of nontailed, ssDN

137 to a third HRV species, Human rhinovirus C, raised questions about the prevalence of these picornavi

138 studies of water quality interventions have raised questions about the risk associated with fecally

139 dexamethasone (RVD) in this population have raised questions about the role and timing of transplant

140 ent receptor types 1 and 2 (CR1 and CR2) has raised questions about the role of C3d-CR2 interactions

141 ection of two CDT-negative clinical isolates raised questions about the role of CDT in some cases of

142 proteins within mRNA processing bodies have raised questions about the roles of the Ccr4-Not complex

143 region for bidirectional signaling with MCM raised questions about the roles of the switch I and II

144 e nuclear power complex in Fukushima, Japan, raised questions about the safe operation of nuclear pow

145 The unexpectedly broken ionic lock has raised questions about the true conformation(s) of the i

146 In addition, recent clinical trials have raised questions about the use of WBRT.

147 n coding for sedation by proceduralists have raised questions about the value of procedural sedation

148 after sleep deprivation in bipolar disorder raises questions about the appropriateness of these meth

149 This raises questions about the appropriateness of using rati

150 tyle of the intestinal parasite Blastocystis raises questions about the biochemistry and function of

151 This raises questions about the biological mechanism(s) that

152 concentrations in many cell culture studies raises questions about the biological relevance of the o

153 short, mismatched ssDNAs into their genomes raises questions about the biological significance of th

154 This raises questions about the cardiovascular side effects a

155 n breastfeeding duration or exclusivity also raises questions about the causal nature of the observed

156 The identification of this new factor raises questions about the causal relationships between

157 This raises questions about the cellular capacity for adaptat

158 mall size of the treatment effects, however, raises questions about the clinical utility of this proc

159 vascular risk factors in both conditions and raises questions about the current separation of the two

160 conserved proteins in multiple processes and raises questions about the endogenous substrate(s) and r

161 availability of so many approved treatments raises questions about the ethics and safety of placebo-

162 The work also raises questions about the evolutionary changes in this

163 t adopt at least five different folds, which raises questions about the evolutionary processes that m

164 thematics (STEM) settings is provocative and raises questions about the extent to which gender bias m

165 g microheterogeneity in heme orientation and raises questions about the fidelity of heme incorporatio

166 pression was silenced rapidly by methylation raises questions about the future application of such te

167 This conclusion raises questions about the geographic origins (Old World

168 ng disrupted for a relatively common species raises questions about the impacts on less tolerant grou

169 all aromatic amino groups in metabolites and raises questions about the intermediacy of this species

170 ieved, and the modest efficacy that resulted raises questions about the level of effect that is achie

171 r the selection of both NKT and MAIT subsets raises questions about the mechanisms underlying acquisi

172 empirical evidence regarding empathy, which raises questions about the ordering and modulation of di

173 resulted from human overhunting, its demise raises questions about the Pleistocene overkill model, w

174 This raises questions about the possible off-target binding o

175 This study raises questions about the potential ability of thousand

176 Therefore, this result raises questions about the potential of epsilonretroviru

177 tion structure as putative species, our work raises questions about the practice of genome-based spec

178 lumn evolution in the earliest tetrapods and raises questions about the presumed vertebral architectu

179 nt interest in modeling biochemical networks raises questions about the relationship between often co

180 The diminished V1R repertoire in dogs raises questions about the relative contributions of V1R

181 This raises questions about the relative importance of these

182 This difference raises questions about the relevance of TCR to neurologi

183 s been suggested as a mechanism, recent work raises questions about the role of biofilms in CF.

184 processing in the primate visual system and raises questions about the role of dorsal lateral genicu

185 This raises questions about the role of GR in maintaining the

186 high prevalence of traditional risk factors raises questions about the role of NADPH oxidase in the

187 citation in the epileptic hippocampus, which raises questions about the role of sprouting and adult n

188 This raises questions about the role of TNFR2 signaling in th

189 This raises questions about the safety of consumers, and it s

190 The cleavage of CoA raises questions about the side of the membrane where th

191 This finding raises questions about the sites for doped oxygen, the m

192 polarity and compartmentalization of neurons raises questions about the spatial and temporal regulati

193 wever, the discovery of histone demethylases raises questions about the stability of histone methylat

194 last, and glycosylation in the cytoplasm, it raises questions about the subcellular localization of g

195 E sequence were incorporated into the genome raises questions about the threat of ectopic recombinati

196 lon with subsequent referral for colonoscopy raises questions about the threshold of polyp size that

197 This raises questions about the typical anti-viral capability

198 The insect's successful performance raises questions about the underlying mechanisms.

199 ange between commercial and exhibition swine raises questions about the understudied interface betwee

200 This assumption raises questions about the validity and utility of curre

201 s and genes required to survive that stress, raising question about the role of stress-activated gene

202 e variable and not especially distinct, thus raising question about the utility of executive impairme

203 for tropical rainforest hunter-gatherers but raising questions about the antiquity of this behavior.

204 light chain LC7 recognition sequence on IC, raising questions about the apparently contradictory eff

205 nding on how the average ZT values are used, raising questions about the applicability of ZT in the c

206 rapies compared with chemotherapeutic drugs, raising questions about the assessment of changes in tum

207 and MORB do not appear to be in equilibrium, raising questions about the cogenetic relationship betwe

208 on the rhythm by cADPR overexpression, thus raising questions about the conclusions of Dodd et al.

209 y, they are evolutionarily distantly related raising questions about the conservation of the RNAi pat

210 in phenotype even within affected families, raising questions about the determinants of the progress

211 atric surgery for severe adolescent obesity, raising questions about the durability of early response

212 nt treatment failures in cases of skin rash, raising questions about the efficacy or suitability of t

213 only recombinant HCV to have spread widely, raising questions about the epidemiological background i

214 cy do not develop the characteristics of DC, raising questions about the etiology of DC and/or mouse

215 ' task faster than many tool-using primates, raising questions about the evolution of sophisticated p

216 not expressed near the caudal limit of Otx, raising questions about the existence of an MHB organize

217 cross almost the entire Greenland ice sheet, raising questions about the frequency and spatial extent

218 allosum were generated after 7 weeks of age, raising questions about the function of the late-myelina

219 ates with lysosome subcellular localization, raising questions about the functional implications and

220 e revealed ordered internal water molecules, raising questions about the functional role of those wat

221 ates of stroke to approximately 1% per year, raising questions about the generalizability of these pr

222 microorganisms in a PGN-independent manner, raising questions about the identity of the bPGRP-S liga

223 acid is key in integrating these responses, raising questions about the impact of altering GA respon

224 nger effects on common carotid IMT in women, raising questions about the mechanism of the causal SNP

225 ulation is eliminated during postnatal life, raising questions about the nature and purpose of the co

226 the genes to synthesize lipopolysaccharide, raising questions about the nature of the inducing molec

227 orer has been observed at several locations, raising questions about the nature, distribution and dyn

228 an small glomeruli from children and adults, raising questions about the origin of these podocytes.

229 1 as a Ca(2+) sensor for fast SV exocytosis, raising questions about the physiological significance o

230 use and confinement in livestock production, raising questions about the potential for occupational e

231 rae but has not been found in many bacteria, raising questions about the prevalence and function of c

232 pulations of naive T cells can be recognised raising questions about the processes that give rise to

233 s appear to be confined by crystal contacts, raising questions about the putative large-scale induced

234 cause of the emergence of a different clone, raising questions about the relevance of CMR in ET patie

235 rent depending on the modeling methods used, raising questions about the reliability of ensemble proj

236 ected variation among the ecological models, raising questions about the reliability of forecasts bas

237 ay reflect inhibition of FICZ metabolism and raising questions about the reported promiscuity of the

238 implements the formalism in a different way, raising questions about the reproducibility of such pred

239 anisms, including some Vibrio genus members, raising questions about the role of microplastics as a n

240 e become available for treatment of myeloma, raising questions about the role of SCT for its manageme

241 ence of 2 viral lineages within West Africa, raising questions about the roles of reduced air traffic

242 shold in the acoustic brainstem response, so raising questions about the significance of PIEZO2 in th

243 d spiral organization of the ATPase domains, raising questions about the significance of the conforma

244 tributes to localization of the MSL complex, raising questions about the source of the siRNAs involve

245 ly from a spectrum of cardiac abnormalities, raising questions about the specific functions of this t

246 sfully passed a narrow gap frequently burst, raising questions about the sperm discharge mechanism in

247 show that climate change continues unabated, raising questions about the status of the "hiatus".

248 to induce otic tissue in ectopic locations, raising questions about the sufficiency of Fgf and the d

249 ain small fractions of phenotypic variation, raising questions about the use of further studies.

250 the term 'race' to human population groups, raising questions about the validity of inferences made

251 th an ecotropic murine leukemia virus (MLV), raising questions about the validity of results obtained

252 banks they have collected are well suited to raising questions about the validity of the existing dia

253 ble effect on CKD or mortality months later, raising questions about the value of using small to mode

254 Montsechia is Barremian in age, raising questions about the very early divergence of the

255 e hundreds of generations, observations that raise questions about their contribution to natural vari

256 quire different computational approaches and raise questions about their effectiveness on plant data.

257 ution, but competing phylogenetic hypotheses raise questions about their relationships, biogeography,

258 Inconsistencies between these trends raise questions about their reliability, especially beca

259 tic resonance spectroscopy data and analyses raise questions about their results.

260 rgs from Antarctica over the past decade has raised questions about their potential impact on the sur

261 e (PR5-L) sequences in nematodes and insects raises questions about their evolutionary relationships.

262 f neuron-specific endocytic protein isoforms raises questions about their importance for specialized

263 on of many HDAC isoforms in eukaryotic cells raises questions about their possible specificity or red

264 on structures of amelogenin protein in vitro raises questions about their role in enamel formation.

265 ms and have their own scoring systems, which raises questions about their similarity and the potentia

266 reveals NADPH-enriched populations of cells, raising questions about their distinct metabolic roles.

267 -specific Cre-recombinase transgenic models, raising questions about their general usefulness in rese

268 e, despite limited absorption and digestion, raising questions about their mechanism of action.

269 e too short for Dicer to excise their loops, raising questions about their mechanism of action.

270 emarkably broad-spectrum virocidal activity, raising questions about their modes of membrane associat

271 rotid gland express both IK and BK channels, raising questions about their particular respective role

272 have been caused by GII.4 genotype strains, raising questions about their persistence in the populat

273 This difference raises questions about understanding the catalytic role

274 Our study raises questions about using snapshots of ES provision a

275 ordant in Parkinson disease clinical trials, raising questions about validity of these imaging measur

276 require thoughtful measurement decisions and raise questions about what a spatial effect represents.

277 for recombination hotspots in eukaryotes but raises questions about what forces have driven such rapi

278 ne may weave through itself in complex ways, raising questions about what sequence of events might ha

279 o the complexity of decision-making and have raised questions about whether a finite course of pegyla

280 These observations have raised questions about whether microchimeric cells are r

281 s adverse events with rosiglitazone use have raised questions about whether the evidence of harm just

282 ling by glutamate, but this distribution has raised questions about whether the protein actually cont

283 These findings raised questions about whether these vascular defects we

284 om, identified by gene ablation studies, has raised questions about whether they are directly mechani

285 ever, the low bioavailability of resveratrol raises questions about whether the antidiabetic effects

286 aps for a number of different organisms, and raises questions about whether the divergence of Plasmod

287 ociation with multiple filled prescriptions) raises questions about whether this association is causa

288 response to the mode of infant milk feeding, raising questions about whether formula feeding ought to

289 rted in up to 40% of the general population, raising questions about whether it is a distinct patholo

290 lation of several tyrosine kinase receptors, raising questions about whether oncogenic tyrosine kinas

291 pend on the spread of signals between cells, raising questions about whether PD are in different func

292 "Long-term study" of DC is raising questions about whether the procedure should be

293 otocols, but their phenotypes often overlap, raising questions about whether they are truly distinct.

294 n prostatic intraepithelial neoplasia (PIN), raising questions about whether TMPRSS2-ERG contributes

295 nd AURELIA, also showed improvements in PFS, raising questions about whether VEGF-inhibiting agents s

296 etic studies in this issue of Molecular Cell raise questions about which polymerases are copying the

297 various other agents can also cause changes, raising questions about which mechanisms are dominant.

298 ut some express up to five different toxins, raising questions about which toxins are necessary for t

299 D in infected captive cervid populations and raise questions about why some prion strains develop dru

300 ght have evolved sexual dimorphism, but also raise questions about why the putative ancestral-like MT