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1 n the Randomized Aldactone Evaluation Study (RALES).
2 ironolactone initiation after publication of RALES.
3 eased >7-fold (3.0% to 21.3% P<0.0001) after RALES.
5 emia, low systolic blood pressure, pulmonary rales above the bases, or an exacerbation of known ische
7 increased markedly after the publication of RALES, and many treated patients were at risk for hyperk
9 ngham Criteria variables (dyspnea, pulmonary rales, cardiomegaly, interstitial or pulmonary edema on
10 n findings typical of interstitial fibrosis (rales, clubbing, or cyanosis) raised the risk of subsequ
11 r the Randomized Aldactone Evaluation Study (RALES) demonstrated a 30% mortality benefit for treating
13 f the Randomized Aldactone Evaluation Study (RALES) in national cohorts of older patients hospitalize
14 confidence interval {CI}, 1.2-4.1]), to have rales on examination (OR, 1.9 [95% CI, 1.0-3.7]), to be
17 ase, atrial fibrillation, diabetes mellitus, rales, peripheral edema, higher New York Heart Associati
20 Clinical follow-up does not adhere to the RALES trial guidelines, resulting in higher complication
21 setting, we analyzed the application of the RALES trial protocol to the care of 104 patients, whom w
25 (Randomized Spironolactone Evaluation Study [RALES] trial), we noted a marked increase in widespread
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