ライフサイエンスコーパス: ramp

1 cts a robust analysis of metabolic pathways (RAMP).

2 call Ratio Analysis of Multiple Precursors (RAMP).

3 g the repeat-associated mysterious proteins (RAMPs).

4 on sloped terrain (as in traversing hills or ramps).

5 three receptor activity-modifying proteins (RAMPs).

6 ydraulic retention time over the temperature ramp.

7 eedback to stabilize pitch as it drove off a ramp.

8 ints over a virtually continuous temperature ramp.

9 osed mechanisms are responsible for dopamine ramps.

10 tor network models predict slow depolarizing ramps.

11 different levels are connected by helicoidal ramps.

12 ls are used to monitor responses to temporal ramps.

13 ons, a single LTS could be evoked by current ramps.

14 d found expression correlation for GPCRs and RAMPs.

15 axial electric field distortion and voltage ramping.

16 ant stress and stress-varying magnetic field ramping.

17 e-step (10 degrees C within a day) or a slow ramping (0.1 degrees C/day for 100 days) temperature inc

18 Receptor activity-modifying proteins (RAMPs) 1, 2, and 3 are unusual accessory proteins that d

19 both receptor activity-modifying protein-1 (RAMP-1) and calcitonin receptor gene (CT-R) expression i

20 y acute physiologically relevant temperature ramps (11-23 degrees C), the network frequency and phase

21 reshold was for the 8-milliseconds ascending ramp (14.6+/-7.3 J [mean+/-SD]), which was significantly

22 stimulating MFC D1DR neurons could increase ramping activity among MFC neurons.

23 Finally, interval timing and striatal ramping activity are disrupted when the medial frontal c

24 d that MFC D1DR blockade strongly attenuated ramping activity of MFC neurons that correlated with beh

25 ensory responses of the subthalamic nucleus, ramping activity of the subthalamic nucleus, and movemen

26 as we observed that MFC neurons with strong ramping activity tended to be coherent with stimulus-tri

27 Furthermore, we found that striatal ramping activity was correlated with and dependent upon

28 No such smooth-ramping activity was observed in DS ensembles as firing

29 surement to production and was followed by a ramping activity whose slope encoded the previously meas

30 Network models can produce persistent and ramping activity, but the positive feedback that is crit

31 First, "ramping" activity, a monotonic change in neuronal firing

32 -timing tasks and found that time-dependent "ramping" activity, a monotonic increase or decrease in n

33 We benchmark RAMP against traditional FBA on genome-scale metabolic r

34 selectivity and support the hypothesis that RAMPs allosterically modulate CTR peptide affinity.

35 ns and restitution slope during cycle-length ramping alternans control, was designed and validated.

36 ozone observations only in contrast with the RAMP and a Constant Air Quality Model Performance (CAMP)

37 behavior, midway through the path we imposed ramp and hold translation perturbations of the support s

38 aining additional oligonucleotide-conjugated Ramp and horseradish peroxidase (HRP).

39 ells to characterize the effect of different RAMP and ligand combinations on this pathway.

40 vent composition range covered by the mixing ramp and on the available pressure.

41 POL beta incorporated rAMP and rCMP opposite 7,8-dihydro-8-oxoguanine (8-oxodG

42 h were correlated with both the slope of the ramp and the monkey's corresponding production interval

43 opic control, we are able to demonstrate how ramped and phase-modulated spin-lock radiation can enhan

44 Temperature-ramping and isothermal anisotropy measurements reveal th

45 We discovered that RAMPs and GPCRs tend to have orthologs in the same speci

46 In humans, there are three RAMPs and over 800 expressed GPCRs, making direct experi

47 Detection and recognition of ramps and steps are important for the safe mobility of p

48 ght into factors affecting the visibility of ramps and steps for people with low vision.

49 ults suggest global coevolution of GPCRs and RAMPS and support the hypothesis that GPCRs interact glo

50 rational stresses are negligible for typical ramp-and-hold stimuli.

51 firing frequencies in response to mechanical ramp-and-hold stimuli.

52 activity in M1 in two behavioral phases of a ramp-and-hold visuomotor adaptation paradigm.

53 between walking on level ground, stairs, and ramps--and of the ability to reposition the leg while th

54 as equally apparent when the slow irradiance ramp appeared alone or when a variety of higher-frequenc

55 variability in model performance, our novel RAMP approach is able to extract more information in ter

56 Regionalized Air Quality Model Performance (RAMP) approach to integrate chemical transport model (CT

57 These ramps are commonly assumed to reflect the gradual accumu

58 Receptor activity-modifying proteins (RAMPs) are widely expressed in human tissues and, in som

59 tly between the two contraction modes for SL ramps as fast as 5 ms.

60 ms in which grid fields are produced by slow ramps, as in attractor models, whereas theta oscillation

61 rcuit trials involving level-ground walking, ramp ascent and descent, and stair ascent and descent.

62 The RAMPs augment the binding site with distinct contacts to

63 and holding briefly for 1.0 ms followed by a ramp back down to -0.4 V.

64 with a marked sign-reversal of Cotton effect ramping between Deltaepsilon = +35 M(-1) cm(-1) for [P-1

65 ampling and to enable controlled temperature ramps beyond the present upper limit of about 415 degree

66 as the stochastic elements dissipate, and C) RAMP can identify biologically tolerable diversity of a

67 expensive enzymatic reagents or temperature ramping capabilities associated with RT-PCR-based method

68 Enabling ramping capability for NPPs would raise the limit of PV

69 ase-load nuclear power plants (NPPs) without ramping capability in the region limits PV integration l

70 ng the population bursts of CA3-CA1 neurons (ramping cells).

71 ferred conformation of peptides that require RAMPs; CGRP, AM, and amylin.

72 ensity-step changes (clouds and shadows) and ramp changes (sunrise), respectively.

73 How peptides selectively bind GPCR:RAMP complexes is unknown.

74 nd may inform drug development targeting CLR:RAMP complexes.

75 Using a pulsed power generator, we ramp compress spherical gold nanoparticle arrays to pres

76 Our dynamic magnetic ramp compression approach produces smooth, shockless (th

77 pproach applies magnetically driven uniaxial ramp compression to mimic established embossing and impr

78 Recent developments in shock-free dynamic (ramp) compression now allow laboratory access to this de

79 Here we describe ramp-compression measurements for diamond, achieving 3.7

80 is, human subjects performed slow triangular ramp contractions of the ankle dorsiflexors in the absen

81 e effects of this mutation on activation and ramp current are dominant over the reduced persistent cu

82 ar frequency-current responses to triangular ramp current injections.

83 ional variants of Nav1.8 that either enhance ramp current or shift activation in a hyperpolarizing di

84 stent late sodium current and an increase in ramp current.

85 The mutation increases ramp currents in response to slow depolarizations.

86 activation, enhanced persistent and enhanced ramp currents may be related to the approximately -40 mV

87 nhance currents evoked by slow ramp stimuli (ramp currents).

88 e inactivation, faster repriming, and larger ramp currents, override the depolarizing shift of activa

89 ases in amplitude of persistent currents and ramp currents.

90 when averaged together, resemble traditional ramping decision signals.

91 n more than it did the output of a standard (ramping) decision-making model, and provided a robust pr

92 ing body development and EPS production in a RAMP-dependent manner.

93 amily of receptors displays both ligand- and RAMP-dependent signaling bias among the Galphas, Galphai

94 e number of action potentials generated by a ramp depolarization, suggesting increased neuronal excit

95 olarizes activation and the response to slow ramp depolarizations.

96 results reveal unexpected differences in how RAMPs determine CTR and CLR peptide selectivity and supp

97 n variability showed that the utilization of ramps, dips, and peaks, with different slopes and minima

98 sient voltages applied to tBLMs by pulsed or ramped direct-current amperometry can, however, provide

99 ation testing was performed using a range of ramp displacements.

100 A 12-week ramp down in both temperature (27 --> 10 degrees C) and

101 sets obtained from leafy spurge exposed to a ramp down in both temperature and photoperiod (RDtp) ver

102 temperature and photoperiod (RDtp) versus a ramp down in temperature (RDt) alone.

103 xylate (ACC) to paradormant plants without a ramp down treatment.

104 Increments with half-ramp durations between 5 and 50,000 ms are used.

105 Prior work has demonstrated that MFC neurons ramp during interval timing, suggesting that they underl

106 ent features (such as codon usage and the 5' ramp effect) in determining the accuracy of predictions.

107 Slower light ramps elicited sustained gamma frequency oscillations, w

108 However, in the adult pulvinar, current ramps evoked multiple LTSs in >70% of recorded neurons.

109 most of the observed effects in temperature-ramp experiments are due to entropic effects (fitting wi

110 Voltage-clamp slow-ramp experiments showed that serotonin caused a strong i

111 he problem of relating force-clamp and force-ramp experiments, and identify a linker and loading rate

112 n of rupture forces in force-clamp and force-ramp experiments, respectively.

113 QCM temperature ramping experiments identified domains of different phas

114 sed motion information acquired in the short-ramp extinction presentation to track the target from th

115 In the first of each pair (short-ramp extinction) the target was visible for only 150 ms.

116 e shifting, known from isothermal and normal ramped fast-GC systems, are overcome.

117 s in rodents, monkeys, and humans, including ramping firing rates between the onset of reward-predict

118 A ramp/flat fault plane can introduce an anticline with be

119 A compressive force introduced by a ramp/flat fault was suggested as its origin of formation

120 tion with ICAM-1 mainly corresponds to force ramps followed by sudden jumps.

121 s Laboratory University of Udine temperature ramp), for the collection of hydrogen-deuterium exchange

122 d-particles were then subjected to a heating-ramp from 22 to 44 degrees C.

123 e, which is set by reversing the temperature ramp from heating to cooling during the MIT.

124 ized its behavior in response to temperature ramps from 7 degrees C to 31 degrees C.

125 properties were characterized by Temperature-Ramp FTIR, DSC & CMC measurements.

126 These RAMP genes are indispensable for CRISPR3* to affect deve

127 In addition, the resulting RAMP-GPCR interaction map suggests that RAMP1 and RAMP3

128 However, whether RAMP-GPCR interactions are widespread, and the nature of

129 ng and molecular dynamics simulations of the RAMP-GPCR-G protein complexes.

130 The ascending ramp has a significantly lower defibrillation threshold

131 Moreover, RAMP has the properties that: A) metabolic states are (L

132 Such previously unrecognized functions of RAMPs highlight the need to consider all receptor-intera

133 ocedure involving the metalation of the SAMP/RAMP hydrazones of N-Boc-azetidin-3-one, reaction with a

134 (up to 84% ee) by the metalation of the SAMP/RAMP hydrazones of oxetan-3-one, followed by reaction wi

135 (R)-1-amino-2-methoxymethylpyrrolidine (SAMP/RAMP)hydrazones.

136 Reduced fast ice after 2006 ramped iceberg scouring, killing half the encrusting ben

137 iomarkers, were determined in each sample by RAMP immunoassay.

138 NGFCs exhibited a late firing pattern with a ramp in membrane potential prior to firing action potent

139 rrelated to taste palatability, the apparent ramp in stimulus-aligned choice-related firing was shown

140 in the measurement epoch to the slope of the ramp in the production epoch.

141 However, the ramping in trial-averaged responses could instead arise

142 hypothesis that GPCRs interact globally with RAMPs in cellular signaling pathways.

143 ected at six different cloverleaf freeway on-ramps in Southern Michigan, using 2D images from scannin

144 rgy homeostasis, but the significance of CNS RAMPs in the control of energy balance remains unknown.

145 as employed, in conjunction with temperature ramping, in a practical application to separate a mixtur

146 rom a listening test (N = 10) using linearly ramped increment-decrement envelopes applied to pseudo-c

147 varied whilst contrast was held constant for ramped increments with effective modulation rates betwee

148 The results are discussed in the context of RAMP interactions probed through molecular modeling and

149 These different CLR-RAMP interactions yield discrete receptor pharmacology a

150 s, the traditional ages where people find on-ramps into science, technology, engineering, and mathema

151 PFG NMR associated with a sigmoid gradient ramp is an exciting strategy to study drugs as a whole,

152 ities, although our analysis shows that this ramp is caused by rapid initiation of short genes rather

153 ystalline optical potential is also linearly ramped, light can undergo periodic Bloch oscillations, a

154 ncoding receptor activity-modifying protein (RAMP)-like triterpene glycoside receptor (RL-TGR), a nov

155 rafish, receptor activity modifying protein (RAMP)-like triterpene glycoside receptor (RL-TGR), was p

156 firing rate variance in the ACC was a smooth ramp-like change as the animal progressed through the se

157 easures of fMRI brain activity highlighted a ramp-like increase in orbitofrontal cortex (OFC) that pe

158 However, recent reports of ramp-like increases in dopamine concentration in the str

159 T cells encountering the ramp-like structures exhibited MLC accumulation near hea

160 In this study, we fabricated ramp-like structures with a 5 mum height and various slo

161 tion near head-tail junctions contacting the ramp-like structures, and made turns to the direction pe

162 probability of T cells climbing sharp-edged ramp-like structures, indicating intriguing turning beha

163 ing turning behavior of T cells climbing the ramp-like structures.

164 slopes, and observed T cells climbing up the ramp-like structures.

165 turns to the direction perpendicular to the ramp-like structures.

166 for >1 s) even when subjected to slow force ramps (<10 pN/s).

167 We find that the embryo generates a ramping magnitude of force until it reaches a peak force

168 ter control of ions over the classic voltage ramping mass-selective instability scanning method.

169 Collectively, these suggest that dopamine ramps may be explained, with only minor disturbance, by

170 lem shows that FBA is a limiting case of our RAMP method.

171 atures of the crRNAs associated with the Cas RAMP module (Cmr) effector complex, which cleaves target

172 constructions of native type III Cmr (CRISPR RAMP module) complexes in the absence and presence of ta

173 crete multipoint steady-state and continuous ramped-multipoint data acquisition methods.

174 Third, striatal ramping neurons are correlated with activity of the medi

175 capitulates the previously reported 5'-to-3' ramp of decreasing ribosome densities, although our anal

176 SA-like sheath field in the downward density ramp of the target, leading to an overall broad spectrum

177 eferentially associated with an anticipatory ramping of activity up to the reward sites.

178 toneuron discharge elicited by intracellular ramps of current and the force developed by its motor un

179 measurements of bond lifetimes under steady ramps of force to achieve a direct assay for the off-rat

180 Grid cells had large and reproducible ramps of membrane potential depolarization that were the

181 We injected current ramps of variable slope into neurons that were sufficien

182 lus-evoked synaptic input, current steps and ramps of varied duration, and noise.

183 was achieved through catalysis, by the free Ramp, of a restriction cascade containing additional oli

184 d on: (i) hybridization of a target DNA to a Ramp-oligonucleotide probe conjugate, followed by (ii) s

185 ding the molecular details of the effects of RAMPs on CLR.

186 Voltage-clamp using ramp or repetitive action potentials as commands showed

187 al current-clamp recordings using excitatory ramp or square-step current injections failed to reveal

188 Hospital RAMP outlier status is a rectal cancer surgery composite

189 , high outlier (worse than expected), or non-RAMP outlier using standard observed-to-expected methodo

190 lateral prefrontal cortex (RLPFC) activation ramped over sequence position and reset at the initiatio

191 The trabeculae were subjected to shortening ramps over a range of velocities and the extent of RLC p

192 D is shown to increase towards long duration ramps (p<10(-6)).

193 Continuous 21-day treatment with ramping PDM doses (days 1-7: 0.32 mg/kg/h; days 8-21: 1.

194 were seen that could be broadly described as ramps, peaks, and dips, with different slopes, direction

195 was either provided after each trial of the ramp phase of adaptation when a gradual increase in the

196 First, we inactivated I(Na) using a ramp prepulse to 45 mV.

197 e synthesis factor produces a characteristic RAMP profile that exhibits consistency across a range of

198 Using a voltage ramp protocol, normalized current responses of R222Q cha

199 ns allow us to analyze force-clamp and force-ramp pulling experiments.

200 cellular uptake and pore size, we designed a ramped pulse exposure scheme for optimizing microbubble

201 This new strategy employs a ramped pulse shape, where the maximum amplitude is achie

202 Ramped pyrolysis (RP) targets distinct components of soi

203 Here, a ramped pyrolysis carbon isotope technique is employed to

204 Ramped pyrolysis profiles indicate that the organic mate

205 this requires the reference standard method (RAMP(R) immunoassay)) or alternatively on the basis of t

206 is protonated on the adenines of every other rAMP-rAMP helix base pair.

207 nd 6-sulfo-sialyl Lewis X were impervious to ramp rate changes.

208 the latter ligand, suggesting that the high ramp rate induced similar structural changes as the muta

209 8H substitution in L-selectin eliminated the ramp rate responsiveness of its dissociation from PSGL-1

210 se mutation H108A in P-selectin acquired the ramp rate responsiveness.

211 otein ligand-1 (PSGL-1) loaded at a constant ramp rate to a constant hold force behaved as catch-slip

212 he generator's net efficiency, capacity, and ramp rate.

213 egardless of the strain rate and temperature ramping rate.

214 r lambda phage DNA and H3 influenza RNA with ramp rates and cycle times consistent with traditional P

215 old force behaved as catch-slip bonds at low ramp rates that transformed to slip-only bonds at high r

216 that transformed to slip-only bonds at high ramp rates.

217 ly released from a source region into the on ramp region of the cyclical drift tube and these pulses

218 The amount of Ramp released into solution upon cleavage was proportion

219 tivation and enhanced (approximately 2-fold) ramp response for the mutant channel while robotic recor

220 In voltage clamp, voltage ramps revealed a non-inactivating, low-voltage-activated

221 The characteristics of this ramp-reversal memory effect do not coincide with any pre

222 Two mutant REases for amplification (Ramp), S17C BamHI and K249C EcoRI, were conjugated to ol

223 Using 3D radially ramp-sampled proton MRI, with a combination of adiabatic

224 These dopamine increases (ramps) scaled flexibly with both the distance and size o

225 Temperature-ramped separations of a simple alkane mixture using the

226 agnitude of ktr following step shortening or ramp shortening.

227 , we explore three possible accounts of such ramping signals: (a) the resolution of uncertainty about

228 loying single speed step-ramp target motion (ramp speed = 25 degrees /s) were used before and after a

229 including buffer ionic strength and thermal ramping speed as these parameters both influence the lig

230 We describe temperature-ramped spin-exchange optical pumping (TR-SEOP) in an aut

231 Furthermore, voltage-ramp stimulation proved useful.

232 tivation and enhance currents evoked by slow ramp stimuli (ramp currents).

233 persistent current and the response to slow ramp stimuli by 10- to 11-fold compared with wild-type N

234 Subjects viewed horizontal step-ramp stimuli which occurred in pairs of identical veloci

235 ns, with strain increments from 5% to 50%, a ramp-strain rate of 2% per second, and relaxation period

236 tern of rabbit skeletal muscle fibers during ramp stretch compared to those during isometric contract

237 readmission during the 1 year following the ramp study (total of 18 events; hazards ratio, 1.09; 95%

238 Control trials employing single speed step-ramp target motion (ramp speed = 25 degrees /s) were use

239 neurons in the monkey during pursuit of step-ramp target motion.

240 Both ramped temperature and isothermal thermogravimetric anal

241 The B value from the tensile ramp test also was significantly lower in the affected g

242 We devised a unique ramp test protocol to be routinely used at the time of d

243 d during an echocardiography-monitored speed ramp test.

244 re, normalization of decoupling (n=8) during ramp testing was significantly associated with higher 1-

245 al and heart failure readmission rates after ramp testing were assessed.

246 LVADs underwent routine invasive hemodynamic ramp testing with right heart catheterization, during wh

247 er adjustment of their rotation speed during ramp testing, 30 patients (48%) had inappropriate decoup

248 iesel particle filter (DPF), driven on speed ramp tests and transient cycles.

249 Ramp tests facilitate optimal speed changes and device m

250 Fifty-two ramp tests for 39 patients were prospectively collected

251 Seventeen patients had ramp tests performed for suspected device thrombosis, an

252 Twenty-eight ramp tests were performed for speed optimization, and sp

253 the presence of dissociation points or "exit ramps" that naturally would terminate sliding.

254 spital risk-adjusted margin positivity rate (RAMP) that allows identification of performance-based ou

255 n eject at the ss(z) = 1 instability line by ramping the amplitude of the drive rf potential applied

256 cation of the individual oligomers by slowly ramping the probe temperature and collecting data-depend

257 locity traveling-wave ion mobility settings, ramping the traveling-wave velocity increased drift spac

258 ases in recently fixed carbon during thermal ramping, thereby maintaining overall increases in isopre

259 We applied RAMP to examine how endonucleolytic cleavages of the mou

260 (e.g., 37 and 615 Hz) superimposed onto a dc ramp to quantify the close-to-reversible Fc(0/+) process

261 p from the surface and the probe temperature ramped to liberate the sampled materials into the gas ph

262 s study further highlights the importance of RAMPs to CLR pharmacology and to bias in general, as wel

263 Tethering RAMPs to CTR enhanced binding of rAmy, CGRP, and the AMY

264 SL with contractions observed after rapid SL ramps to that same SL just before activation.

265 it adaptation experimentally, we used a step-ramp tracking with two different velocities (adaptation

266 ea, a face-space coding model with sigmoidal ramp tuning provided a better account of the data than o

267 ecifically, firing rate has been observed to ramp up or down in a manner resembling the accumulation

268 of five targets: a single step up or down, a ramp up or down, or a flat continuation of the sidewalk.

269 or for Africa and the WHO Executive Board to ramp up routine immunization (RI) activities, began to i

270 ploying a GC column and detector temperature ramp up to 220 degrees C.

271 ine concentration changes were detected that ramped up as rats executed each action sequence and decl

272 Non-Chinese primary production ramped up at a speed of 4% of total market volume per ye

273 in the bilayer of the cubic mesophase can be ramped up stepwise from less than a milligram per millil

274 Furthermore, ramping up and rapid loss of activity were closely assoc

275 ogical blockade of cholesterol absorption by ramping up de novo sterol synthesis through activation o

276 calories that are burned off effortlessly by ramping up energy expenditure?

277 While it is known that ramping up laser pump power increases the amplitude of s

278 e-transcriptase inhibitors, and the standard ramp-up dosing strategy.

279 patients were treated with a weekly stepwise ramp-up in doses as high as 400 mg per day.

280 ), we projected the impacts of a countrywide ramp-up of transfusion therapy.

281 starting at 20 mg per day with stepwise dose ramp-up over 5 weeks to 400 mg per day.

282 Treatment commenced with a 3-week dose ramp-up period for most patients in dose-escalation coho

283 of virus isolated from the donors during the ramp-up phase of acute infection, and three monkeys infe

284 als is approximately 16 times slower than in ramp-up plasma virus recipient animals and approximately

285 Furthermore, L2/3 acquired a ramp-up response temporal profile, potentially encoding

286 ted once daily venetoclax with a weekly dose ramp-up schedule (20, 50, 100, 200, 400 mg) over 4-5 wee

287 A gene-activation or gene-specific ramp-up strategy would be generally helpful if such coul

288 rithm of eight ablations that were gradually ramped-up to 50 W, until full impedance.

289 IP) area exhibit firing rates that appear to ramp upward or downward during decision-making.

290 It is unclear whether RAMPs use a similar mechanism to modulate CTR affinity f

291 information available from slow temperature ramps versus ballistic temperature jumps is presented.

292 es of operation: deterministic integration ("ramping") versus stochastic decision-making ("jumping"),

293 rents in hERG R56Q channels during a dynamic ramp voltage clamp.

294 loss, CUE, and MBC were greater in the slow (ramp) warming treatment.

295 A tensile ramp was performed following DMA.

296 n I was significantly less for the ascending-ramp waveform (0.80+/-0.54 ng/mL) than for the truncated

297 were determined for 11 waveforms-3 ascending-ramp waveforms, 3 descending-ramp waveforms, 3 rectiline

298 rms-3 ascending-ramp waveforms, 3 descending-ramp waveforms, 3 rectilinear first-phase biphasic wavef

299 st was recorded during a heating temperature ramp where carbon monoxide (CO) and hydrocarbon (HC) lig

300 raised to various levels, either stepwise or ramp-wise, while keeping upstream pressure constant.