ライフサイエンスコーパス: rapid

1 tation is most severe and land use change is rapid.

2 within cascade reaction sequences to provide rapid access to a diverse array of different heterocycli

3 This method opens a rapid access to gamma-substituted propyl-1,1-diesters, k

4 A versatile and rapid access to various chain lengths of ethylene-bridge

5 neurons as nerve activity produces large and rapid acid loads in presynaptic terminals.

6 nts implicated in the mechanism of action of rapid-acting antidepressant ketamine: activation of brai

7 CXCL12 treatment also produced rapid activation of STAT3, NFkappaB, and MAPK signaling

8 Rapid adaptive changes can result from the drastic alter

9 Rapid advances in genome sequencing make it possible to

10 We propose that rapid alteration of PTEN activity through changes in its

11 A major challenge is the lack of a rapid and accurate point-of-care (PoC) device that can p

12 cular dynamics (DMD) platform, iFoldNMR, for rapid and accurate structure modeling of complex RNAs.

13 segregated inputs from two ears and display rapid and compartment-specific reorganization in respons

14 A lateral flow assay (LFA) can provide a rapid and cost-effective means to detect targets in situ

15 rom rice, sorghum, and Brachypodium revealed rapid and dynamic changes only occurring to the Ae. taus

16 tivation of the MAPK/ERK pathway mirrors the rapid and dynamic induction of DLL4 transcription and th

17 to determine food adulteration efficiently, rapid and easy-to-use on-site analytical methods are nee

18 coupled with mass spectrometry (HDXMS) is a rapid and effective method for localizing and determinin

19 inty during an epidemic outbreak can lead to rapid and efficient decision making, provided that the u

20 that fluorescence spectroscopy could offer a rapid and high-throughput screening method for identific

21 Condensin's translocation activity is rapid and highly processive, with individual complexes t

22 ts of a quorum-sensing (QS) apparatus have a rapid and potent killing phenotype following microinject

23 ertebrates rely on fast sensory encoding for rapid and precise initiation of startle responses.

24 The rapid and progressive neurodegeneration in MoCD presents

25 Rapid and reliable detection of disease-associated DNA m

26 ses in SNL, these ultrathin 2D films display rapid and reversible red-blue color change upon the wett

27 This metric allows rapid and rigorous evaluation of specimen preparation me

28 e immunization of rhesus macaques elicited a rapid and robust antibody response, conferring complete

29 ketamine hydrochloride's ability to produce rapid and robust antidepressant effects in patients with

30 C57BL/6NJ but not C57BL/6J mice showed rapid and robust escalation in palatable food consumptio

31 idal science, in which the former allows for rapid and robust synthesis of complex particles, and the

32 enic substrates for bacterial enzymes allows rapid and specific detection of M. tuberculosis in live

33 high cargo capacity was constructed for the rapid and stable expression of recombinant proteins in d

34 We infer rapid and sustained ice-sheet retreat driven by MICI, co

35 sure to cocaine and the test chamber induced rapid and transient NPAS4 expression in a small subpopul

36 The most rapid and well documented cases of island dwarfing known

37 n be improved by introducing cost-effective, rapid, and high-throughput fabrication techniques and lo

38 es are affordable, sensitive, user-friendly, rapid, and scalable for manufacturing.

39 dress these limitations due to its low-cost, rapid, and simple features, but the poor analytical sens

40 A rapid anti-diastereoselective halocyclization of these s

41 Conversely, dHc TLQP-62 infusion had rapid antidepressant efficacy, which was reduced in BDNF

42 defined as fatal or nonfatal aortic rupture, rapid aortic growth (>10 mm/y), aneurysm formation (>/=6

43 -) under the UV-vis spectroscopy through the rapid appearance of deep pink color.

44 The availability of rapid approaches for quantitative detection of biomarker

45 Rapid Arctic warming is expected to increase global gree

46 two-step integrated protocol creates a more rapid autoinductive cascade than previously reported, as

47 Biosensors can deliver the rapid bacterial detection that is needed in many fields

48 Kinetic assays showed rapid bactericidal effect of LyeTxI against all periodon

49 The presented RAPID biosensor platform is significantly faster and les

50 howed binding in the PD-L1-rich spleen, with rapid blood clearance through the kidneys and bladder.

51 mally requires highly sensitive tracers with rapid blood clearance.

52 posure to painful stimuli during a period of rapid brain development, before pain modulatory systems

53 e (NHP) PET imaging studies, [(18)F]8 showed rapid brain uptake and high target specificity, indicati

54 Rapid cancer cell proliferation promotes the production

55 Coastal wetlands are sites of rapid carbon (C) sequestration and contain large soil C

56 ium (LCM)-treated C2C12 myotubes underwent a rapid catabolic response in a TLR4-dependent manner, inc

57 The rapid catalytic ability of the chalcogel-supported Pt na

58 Unexpectedly, in the rapid cell cycles preceding the midblastula transition,

59 re, formation of a single, compact speck and rapid cell-death induction in vivo requires a full-lengt

60 in physiological media and facilitates their rapid cellular internalization, making them effective TL

61 ciate with corals have the capacity for more rapid change, potentially aiding the adaptation of long-

62 These measurements reveal rapid changes in protein-RNA interactions within 1 min f

63 on and competition experiments, we show that rapid changes in sperm velocity are mediated by seminal

64 des a new and comparatively cheap tool for a rapid characterisation of water and soil DOM.

65 ning protein-protein interactions enable the rapid characterization of engineered binding proteins an

66 the proposed methodology could be considered rapid, cheap and environmentally friendly.

67 d dose per cubic centimeter at 40-60 min and rapid clearance from blood to kidney and bladder.

68 Rapid climate change is anticipated in tropical regions

69 nt mechanism that organisms use to cope with rapid climate change.

70 Rapid climate warming has resulted in shrub expansion, m

71 mental protocols, thus limiting their use as rapid clinical screening tools.

72 These action potentials (APs) cause rapid closure of the trap and activate secretory functio

73 solid organobase has been developed for the rapid construction of a novel class of densely functiona

74 and when released from the surface underwent rapid contraction.

75 as designed with a diamond-embedded tip (for rapid cooling) and 6 surface thermocouples to reflect ti

76 del of osmotic demyelination, we showed that rapid correction of chronic hyponatremia induces severe

77 Rapid cycling (RC) bipolar disorder is considered as a s

78 bipolar disorder, but it is unclear whether rapid cycling bipolar disorder is linked to highly alter

79 Patients with a history of psychosis or rapid-cycling bipolar disorder were excluded.

80 P (db-cAMP), BAY60-6583 or Cicaprost induced rapid cytoskeleton remodelling and inhibited proliferati

81 nd does not represent a single response to a rapid decline in atmospheric pCO2 at the EOT.

82 without HF, and 22% of patients with HF had rapid decline in eGFR compared with 8.5% in patients wit

83 proper fuel availability as evidenced by the rapid decline in neuronal function during ischemic attac

84 re 34 weeks were characterized by an initial rapid decrease in risk with increasing intake (P for non

85 with tocilizumab in 13 subjects resulted in rapid defervescence (median, 4 hr) and clinical improvem

86 e formed during this seismic cluster records rapid degassing of CO2, suggesting an interval of anomal

87 We recently reported that ischemia induced rapid degradation of tight junction protein occludin in

88 uencies because of reduced activation of the rapid delayed-rectifier current IKr.

89 tmospheric boundary layer undergoes frequent rapid depletions in ozone and gaseous elemental mercury

90 Mi-2beta depletion resulted in rapid deployment of both a pro-inflammatory and an immun

91 A standard rapid desensitization protocol is safe and effective acr

92 hotomous method was also developed to enable rapid detection and avoid tedious calibration.

93 The data show the potential of our assay for rapid detection of antifungal resistance, although the M

94 examples of using this cartridge to perform rapid detection of clinically significant proteoforms fr

95 benefits, but due to their strong odors and rapid deterioration, their application in food formulati

96 veal the potential of Raman spectroscopy for rapid determination (45s) of erucic acid in canola oil.

97 d (ISO 200776-1; 2006) and could be used for rapid determination of antimicrobial susceptibility in a

98 This rapid determination of bacterial sensitivity to differen

99 y (cryo-EM) data processing allowing for the rapid determination of protein structures using a smalle

100 ing strategy for biosensors facilitates both rapid development and small-scale manufacturing.

101 nes for vaccines or therapy, as well as more rapid development of countermeasures against potential b

102 With the rapid development of deep sequencing techniques in the r

103 However, the rapid development of drug resistance has been a major hu

104 involvement of ACTH and TSH and a relatively rapid development of hypopituitarism.

105 the mechanical behaviour of skin due to the rapid development of microneedle devices for drug delive

106 al use, China is attempting to duplicate the rapid development of shale gas that has taken place in t

107 irth, relative to HR infants who showed more rapid developmental progress, as well as relative to all

108 enced by a precision medicine approach, with rapid diagnostic techniques of both bacterial and host f

109 adly reactive and highly sensitive influenza rapid diagnostic tests (IRDTs) are required.

110 arum-specific histidine-rich protein 2-based rapid diagnostic tests (RDTs) to evaluate suspected mala

111 o Feb 27, 2014, who were tested with malaria rapid diagnostic tests (RDTs), and administered question

112 Commercially available rapid diagnostic tests are based upon detection of the i

113 Rapid diagnostic tests based on Plasmodium falciparum hi

114 Rapid diagnostics that enable identification of infectio

115 Rapid diffusion of these DNA-loaded nanocomplexes observ

116 Horizontal gene transfer permits rapid dissemination of genetic elements between individu

117 We demonstrate rapid dissolution kinetics of the microneedles in skin.

118 Our results show how rapid diversification in the immune repertoire immediate

119 ISPR-based diagnostic (CRISPR-Dx), providing rapid DNA or RNA detection with attomolar sensitivity an

120 urthermore, we observed that 1B6 displayed a rapid dose-dependent clearance (t(1/2) 10-60 h) in contr

121 ting environments is vital in the context of rapid ecological change, one of the most potent selectiv

122 incident CKD, incident CKD or mortality, and rapid eGFR decline.

123 rkably, BG505 SOSIP immunization resulted in rapid elicitation of broad and potent serum antibody res

124 The rapid emergence of carbapenem-resistant Klebsiella pneum

125 In recent years, rapid emergence of induced pluripotent stem cells (iPSC)

126 These results suggest that colitis promotes rapid enteric neurogenesis in adult mice and humans thro

127 Rapid epithelial renewal occurs, but the specific cell o

128 olved CO2 near the electrode surface through rapid equilibrium between bicarbonate and dissolved CO2.

129 e implemented EthSEQ to provide reliable and rapid ethnicity annotation from whole exome sequencing i

130 This approach permitted rapid evaluation of over 400 admixture combinations for

131 Colonization events are crucibles for rapid evolution, but it is not known whether evolutionar

132 functions, particularly under conditions of rapid evolutionary change.

133 toluminescent at room temperature, and their rapid excited-state deactivation precludes their use as

134 of moesin from recipient mice supported the rapid expansion of adoptively transferred CD8+ T cells a

135 A Bayesian skyline plot revealed the rapid expansion of CRF01_AE in China around 1999-2000.

136 omote the transition to wakefulness from non-rapid eye movement (NREM) and rapid eye movement (REM) s

137 p cycles: delta (0-3 Hz) activity during non-rapid eye movement (NREM) associated stages was greater

138 lness from non-rapid eye movement (NREM) and rapid eye movement (REM) sleep.

139 during NREM states was lower than Awake and rapid eye movement (REM).

140 sporter (DAT) imaging to identify idiopathic rapid eye movement sleep behavior disorder (IRBD) patien

141 RO5256390 profoundly reduced rapid eye movement sleep in wild-type mice; these effect

142 e oscillations and sleep spindles during non-rapid-eye-movement (NREM) sleep has been proposed to sup

143 e interaction of the cardinal rhythms of non-rapid-eye-movement (NREM) sleep-the thalamo-cortical spi

144 rstanding of the mechanisms and functions of rapid-eye-movement (REM) sleep have occurred over the pa

145 ption of polydimethylsiloxane (PDMS) for the rapid fabrication of microfluidic networks and the utili

146 y, we show that a reduced BCAA diet promotes rapid fat mass loss without calorie restriction in obese

147 whilst fern understories supported the most rapid fire spread, angiosperm shrubs delivered the large

148 FFRangio is a computational method based on rapid flow analysis for the assessment of FFR.

149 investigated for their abilities to promote rapid fluorination at silicon.

150 onical endosomal markers thus reflects their rapid flux towards degradation rather than specific targ

151 rillatory conduction of multiple wavelets or rapid focal activity.

152 ozone or sHA, in part because it facilitates rapid formation of HA-HC complexes.

153 igh flu-specific IgG-antibody titers mounted rapid functional antibodies after infection and experien

154 structural class of amphiphilic peptide with rapid fungicidal activity caused by C. neoformans.

155 Qc SNAREs, and that this assembly undergoes rapid fusion upon addition of Qb and Sec17.

156 ytoplasmic NAD(+) regeneration that sustains rapid glucose breakdown through glycolysis.

157 and M. asiaticum; however, in these samples, rapid growers like M. mageritense occurred at much highe

158 Here we report the rapid growth (seconds) of micrometre-sized, face-centred

159 The human brain undergoes rapid growth in both structure and function from infancy

160 on generally increased with age which showed rapid growth in severe cases.

161 ed for their miniaturization has fuelled the rapid growth of interest in two-dimensional (2D) materia

162 emains a need to anticipate supply given the rapid growth of specialty and subspecialty fellowships.

163 In the wake of this rapid growth, clinicians may lack sufficient information

164 While the field has experienced rapid growth, conceptual and methodological challenges r

165 flowering, the inflorescence stem undergoes rapid growth, with elongation occurring predominantly in

166 Rapid GTP hydrolysis by monomeric Cdc10 drives assembly

167 d robotics, which we demonstrate through the rapid heat dissipation of an elastomer-mounted extreme h

168 A rapid high-performance liquid chromatography method with

169 iomaterial (i.e. BP) and further validates a rapid, high-throughput method for immunoproteomic antige

170 Rapid identification of bacterial infection is essential

171 Nanopore sequencing, have made possible the rapid identification of CGRs with single base pair resol

172 creening' to provide an interactive page for rapid identification of known and putative targets in BG

173 Rapid identification of microorganisms from positive blo

174 Surrogate structures enable the rapid identification of parameters that reveal mechanist

175 re, we describe a high-throughput method for rapid identification of synergistic small-molecule pairs

176 d by an age-related decline that may be more rapid in related donors.

177 e product, and demonstrate the potential for rapid in situ through-container analysis; achieving uneq

178 Country success stories include rapid increases in Kenya, Mozambique, Malawi, Lesotho, S

179 Rapid induction is key to control virus infection, where

180 Cocaine induces the rapid induction of Arc and its nuclear accumulation in s

181 rescent protein (GFP)-knock-in mice revealed rapid induction of gene expression during papilloma indu

182 gen challenge, subjects with atopy displayed rapid induction of upper airway symptoms, an enrichment

183 Here, we describe a rapid, inexpensive, and portable strategy to robustly re

184 emonstrates the potential of the method as a rapid, inexpensive, high sensitivity CVD biomarker assay

185 that converts changes in external K(+) into rapid, 'inside-out' electrical signaling to direct blood

186 Aqua ligands can undergo rapid internal rotation about the M-O bond.

187 t step towards a fully integrated system for rapid label-free separation and on-chip phenotypic chara

188 Therefore a simple, rapid, label free, inexpensive, excellent, sensitive and

189 d-friendly test conditions, we evaluated two rapid lateral flow assays (LFA) for detection of Mycobac

190 Rapid learning can be critical to ensure elite performan

191 ssues (aorta, brain and kidney), resulted in rapid lethality marked by weight loss, changes in nutrit

192 hemokine signaling with timing coherent with rapid LFA-1 affinity activation.

193 gitudinal rotation while swimming, with more rapid longitudinal rotation correlating with swimming pa

194 Moreover, the rapid losses of nucleobases to pond seepage during wet p

195 Rapid, low-cost and portable solution is in highly deman

196 In this article, we report rapid lymphoma development in Id2/Id3 double-knockout mi

197 t scatter specimens were used for downstream rapid matrix-assisted laser desorption ionization-time o

198 ents submitted to orthodontic treatment with rapid maxillary expansion and facemask therapy.

199 high-resolution data acquisition now permits rapid measurement of the width of a peak (Wh), at any he

200 ed to estimate the viability as a simple and rapid method for analysis of nutrient elements in seed k

201 A simple, sensitive and rapid method is proposed for simultaneous determination

202 Microfluidic devices >500 mum, rapid mixing (71% +/- 12% after 5 mm, 100 muL/min) was o

203 t to which these interactions are subject to rapid modulations in response to signals is unknown.

204 In mice, during the rapid muscle atrophy induced by fasting, the desmin cyto

205 The rapid non-linear increase in heat-related morbidity is d

206 cessing, direct microscopic examination, and rapid nonmolecular testing, while approximately 60% perf

207 th heparin plus GPI, possibly because of the rapid offset of bivalirudin's antithrombotic effect duri

208 fficacy of three unique drugs, with reported rapid onset antidepressant properties, is coupled with a

209 after the first known ingestion with typical rapid onset IgE-mediated symptoms.

210 ferrous iron and sulfide in conjunction with rapid oxidant consumption suggested that the sediments h

211 The wavelength-dependent conversion of two rapid photoinduced ligation reactions, i.e., the light a

212 g procedures may make this test suitable for rapid point-of-care detection.

213 Rapid point-of-care testing (POCT) for respiratory virus

214 Poirel (rapid polymyxin NP test) in 2016, detects glucose metabo

215 Here, we show that FXR activation triggers a rapid posttranscriptional mechanism to degrade Cyp7a1 mR

216 to the intercalated disc is a continuous and rapid process critical for intercellular coupling.

217 trating the sensor's suitability to enable a rapid process decision in terms of a successfully perfor

218 the engineered capsular polymerases enabled rapid production of capsular polysaccharides with high y

219 Despite the rapid progress in this area, simultaneous realization of

220 ysis serves to document the considerable and rapid progress within in the field, while also highlight

221 tumors, onset of polyps in adolescence, and rapid progression of some polyps to advanced adenomas.

222 ow-up, which were presumably undergoing more rapid progression.

223 eases; accordingly, these conjugates promote rapid proteasomal clearance of aggregation-prone protein

224 ease, but this remains to be realized due to rapid proteolysis of apelin-derived peptides by protease

225 tches of 49 in 1 h 15 min, which allowed for rapid prototyping and testing of new crystal mounting de

226 The increasing availability of rapid prototyping technology makes it possible to quickl

227 are industry as they offer the advantages of rapid provision of results, ease of use, reduced cost, a

228 Time-lapse imaging reveals rapid pulsatile level changes in Gata2 reporter expressi

229 We infer that Lanzhousaurus had a rapid rate of tooth enamel elongation or amelogenesis at

230 cells that die by apoptosis in vivo is their rapid recognition and engulfment by phagocytic cells (a

231 mension and offers significant advantages of rapid reconstruction without heavy computation during po

232 s a cost-effective and scalable solution for rapid recovery of large STR and SNP datasets in any spec

233 ither 1 or 10 ng venlafaxine, which led to a rapid reduction (90%) of this drug in the embryo at hatc

234 solithic-Neolithic boundary from the Dnieper Rapids region of Ukraine.

235 glacial-interglacial cycles, likely causing rapid regional replacement of biota.

236 te myeloid leukaemia and are associated with rapid relapse and short overall survival.

237 In particular, there is an unmet need in rapid, reliable detection of short RNA regions which cou

238 Our study calls for a rapid removal of PCB-containing materials in animal husb

239 at lower rates of axon degeneration and more rapid remyelination make relapsing MS more resilient tha

240 cle is to assist hospitals in establishing a rapid response for identification, notification, and eva

241 A total of 282,710 rapid response team calls from 274 hospitals were includ

242 Index rapid response team calls occurring on the general wards

243 Regulation of NPQ allows for a rapid response to changes in light intensity and in vasc

244 ann1 mutants showed elevated chitin-induced rapid responses.

245 In addition, microscopy revealed rapid restoration of bladder integrity following chitosa

246 tions in prefrontal sensorimotor control and rapid, reward-dependent reorganization of control dynami

247 rdiology recommends a 0/1-hour algorithm for rapid rule-out and rule-in of non-ST-segment elevation m

248 Together, our data show that the rapid S1P-induced increase in endothelial integrity is m

249 uding humans, flies generate both smooth and rapid saccadic movements to stabilize their gaze.

250 for analytical methods that can both perform rapid sample analysis and overcome the limitations of co

251 We report a rapid "sample-to-answer" platform that can be used for t

252 ier (BBB) models are crucial tools to enable rapid screening of brain-penetrating drugs.

253 ogy has been proposed for several years as a rapid screening tool, whereby negative specimens are exc

254 Rapid sediment clearance occurred that was potentially a

255 Rapid, selective, and highly controllable iridium-cataly

256 se small AIEgens are fruitfully employed for rapid sensing of nitroaromatic compounds (NACs) where pi

257 lly replicate prion diseases and the lack of rapid, sensitive biological screening systems.

258 We developed and validated a rapid, sensitive, and robust method, the polyclonal seru

259 al to be an alternative approach for simple, rapid, sensitive, and selective DNA detection.

260 Rapid, sensitive, and unambiguous identification of biot

261 Rapid separation and efficient ion collection at low pre

262 s suggest DESI-MS as a powerful approach for rapid serous ovarian cancer diagnosis based on altered m

263 Ligandbook enables the rapid set up of reproducible molecular dynamics simulati

264 ry-like phenomena arise from a confluence of rapid, short-lived positive signals driven by the protei

265 eveals that the pool of maternal Vg1 enables rapid signaling at low concentrations of zygotic Nodal.

266 Herein, a novel approach for rapid, simple and cost-effective discrimination/clusteri

267 how the initial state engenders and supports rapid social learning.

268 Mechanistically, TCR stimulation induced rapid sodium influx in Napa(hyh/hyh) CD4 T cells, which

269 h morphokinetic cellular analysis to provide rapid species identification (ID) and antimicrobial susc

270 ing the early-Holocene, was mitigated by the rapid spread of plant taxa.

271 structures among ancient proteins, and more rapid structure evolution of proteins with lower packing

272 hus, our findings support the existence of a rapid subcortical pathway that is nonselective in terms

273 e amygdala first receives visual input via a rapid subcortical route that conveys "coarse" informatio

274 ARE complex interaction that is required for rapid synchronization and Ca(2+) cooperativity of vesicl

275 ctic black hole system V404 Cygni, showing a rapid synchrotron cooling event in its 2015 outburst, we

276 mines, this methodology was used to design a rapid synthesis of (+/-)-vindeburnol from tryptamine in

277 at by avoiding stereochemical issues enabled rapid synthesis of acrylate ketone, ester, and amide ana

278 This method was applied to a rapid synthesis of the spliceosome inhibitor herboxidien

279 A fully automated and rapid system for (99)Tc monitoring is introduced with th

280 /2 and Autotest-VIH), and 1 antigen/antibody rapid test (Alere HIV Combo) for the diagnosis of HIV in

281 ies: the visual immunogold OnSite Leprosy Ab Rapid test [Gold-LFA] and the quantitative, luminescent

282 ogenase (G6PD) status was determined using a rapid test.

283 Inadequate access to rapid testing for Ebola virus disease during the 2014-to

284 be difficult to distinguish clinically, and rapid testing was not available in many Ebola Treatment

285 ys (Architect and Bioplex), 2 antibody-based rapid tests (Vikia-HIV-1/2 and Autotest-VIH), and 1 anti

286 Cell proliferation is essential to rapid tissue growth and repair, but can result in replic

287 The loss of synaptic GluA2 is caused by rapid trafficking of GluA2-containing AMPARs from the ce

288 ing between these metabolic modes requires a rapid transcriptional response and this is orchestrated

289 antidepressant properties, is coupled with a rapid transient rise in glutamate cycling in the medial

290 and interdependent mechanisms that underpin rapid transitions between transcriptional states, and el

291 r overburden cover, which may allow for more rapid transport of MtBE from land-surface releases.

292 Here we use the rapid turnover of venom genes in parasitoid wasps to stu

293 Rapid ultracentrifugation was used to directly measure L

294 ion rate of the environmental quality due to rapid urbanization and industrialization causes a severe

295 he mass spectrometer through a heated inlet, rapid vaporization leads to the formation of molecular i

296 has evolved to small-incisional surgery with rapid visual recovery, good visual outcomes, and minimal

297 a predictive context that was embedded in a rapid visual stream modulated the perception of a subseq

298 insula (WAP), a region which has experienced rapid warming and ecosystem changes.

299 The last phase coincided with rapid warming since 1985, and shows with 33 m per 1 degr

300 ensor systems offer considerable promise for rapid warning regarding personal exposure to OP nerve-ag