ライフサイエンスコーパス: rapidly progressive

1 children and adults, and does not seem to be rapidly progressive.

2 esence of preceding MS, C9ORF72-ALS was more rapidly progressive.

3 younger than 2 months old at diagnosis with rapidly progressive abdominal disease may benefit from e

4 Amyotrophic lateral sclerosis (ALS) is a rapidly progressive, adult-onset motor neuron disease th

5 Clinically advanced and rapidly progressive AIDS-associated Kaposi sarcoma (AIDS

6 Rapidly progressive alcohol-related liver injury was see

7 Rapidly progressive Alzheimer's disease that is associat

8 ary amyloidosis, due to the development of a rapidly progressive amyloid cardiomyopathy.

9 proteins is the hallmark of the late-onset, rapidly progressive and devastating neurodegenerative di

10 l hypertension (PAH), a disorder that can be rapidly progressive and fatal despite current treatments

11 from abnormal liver-function test results to rapidly progressive and fatal hepatic failure.

12 yotrophic lateral sclerosis (FALS) develop a rapidly progressive and fatal motor neuron disease (MND)

13 ical course in Finnish children is uniformly rapidly progressive and fatal.

14 severe crescentic transformation, leading to rapidly progressive and irreversible allograft failure.

15 The clinical course is rapidly progressive and is lethal at a very young age in

16 transition from compensated hypertrophy to a rapidly progressive and lethal cardiomyopathy.

17 d mitochondrial respiratory dysfunction, and rapidly progressive and lethal dilated cardiomyopathy.

18 the patients with Bag3opathy may have had a rapidly progressive and more severe phenotype.

19 among them that meningococcemia is rare and rapidly progressive and patients are widely dispersed ge

20 Type 1 HRS is rapidly progressive and portends a very poor prognosis a

21 Cobalt can cause a distinctive, rapidly progressive and reversible depression of cardiac

22 Clinical presentation was marked by rapidly progressive and severe visual impairment for all

23 human pathogen Pseudomonas aeruginosa causes rapidly progressive and tissue-destructive infections, s

24 ch less frequent in childhood but may have a rapidly progressive and ultimately fatal course.

25 phologic differentiation the cells underwent rapidly progressive apoptosis.

26 Thus patients with rapidly progressive AVCD are treated with a sense of urg

27 fected individuals share a core phenotype of rapidly progressive axonal sensorimotor neuropathy (mani

28 Meningococcemia is an ideal model of a rapidly progressive bacterial infection associated with

29 erm management of corticosteroid-responsive, rapidly progressive, bilateral sensorineural hearing los

30 Rapidly progressive bone loss is one feature of EOP.

31 RF72 cases show the features of a relatively rapidly progressive, but otherwise typical, variant of a

32 f small avascular masses of tumor cells into rapidly progressive cancers is triggered by the angiogen

33 level overexpression of the beta(2)AR caused rapidly progressive cardiac failure in this model.

34 s 4 and 6, alpha-MHC403/403 mice developed a rapidly progressive cardiomyopathy with left ventricular

35 venile onset of myopathy, 8 of whom also had rapidly progressive cardiomyopathy, requiring heart tran

36 ed in the diagnostic workup of patients with rapidly progressive central nervous system syndromes, pa

37 ations include structural abnormalities (eg, rapidly progressive cerebellar atrophy), myopathies (inc

38 mutations in the ABCD1 gene, which lead to a rapidly progressive cerebral inflammatory demyelination

39 Meningococcal disease is a rapidly progressive childhood infection of global import

40 on of manganese in these patients results in rapidly progressive childhood-onset parkinsonism-dystoni

41 vations, we hypothesize that during ACS, the rapidly progressive clinical course that can occur is ca

42 a more aggressive large cell lymphoma with a rapidly progressive clinical course.

43 neoplasm with cutaneous manifestations and a rapidly progressive clinical course.

44 e children who died at our institution after rapidly progressive clinical deterioration from this inf

45 A 62-year-old man presented with rapidly progressive cognitive decline associated with at

46 While the severe type I mouse model has a rapidly progressive condition mimicking type I SMA in hu

47 e a clinical spectrum ranging from a severe, rapidly progressive congenital or early infantile enceph

48 All four patients had a rapidly progressive course and have become mute and non-

49 le in different individuals, spanning from a rapidly progressive course to a long-term asymptomatic i

50 ho fail to respond to steroids or who have a rapidly progressive course.

51 nterferon alpha-2a and ribavirin may trigger rapidly progressive CR in patients with therapeutic immu

52 ce of congenital scoliosis is critical, as a rapidly progressive curve may lead to significant deform

53 ly surgical treatment is often necessary for rapidly progressive curves.

54 al for microRNA (miRNA) processing, leads to rapidly progressive DCM, heart failure, and postnatal le

55 Nephrogenic systemic fibrosis (NSF) is a rapidly progressive, debilitating condition that causes

56 Patients with ALS suffer from rapidly progressive degeneration of motor neurons ultima

57 the differential diagnosis of patients with rapidly progressive dementia (RPD).

58 acterized by organic sleep related symptoms, rapidly progressive dementia and sympathetic symptoms.

59 An early and accurate in vivo diagnosis of rapidly progressive dementia remains challenging, despit

60 on-time MR images in an elderly patient with rapidly progressive dementia represents a specific findi

61 ed with HIV clade B, some patients develop a rapidly progressive dementia that if untreated results i

62 Rapidly progressive dementia, altered behavior, and cere

63 Four of the patients developed rapidly progressive dementia, and the other 2 patients h

64 The classic triad of symptoms consists of: rapidly progressive dementia, myoclonus and typical elec

65 sporadic Creutzfeldt-Jakob disease (sCJD), a rapidly progressive dementia.

66 sporadic Creutzfeldt-Jakob disease (sCJD), a rapidly progressive dementia.

67 ly distinguishing treatable from untreatable rapidly progressive dementias and for future therapeutic

68 Because many rapidly progressive dementias are treatable, it is param

69 onditions that typically develop over years, rapidly progressive dementias can develop subacutely ove

70 Creutzfeldt-Jakob disease (CJD) and nonprion rapidly progressive dementias is important and sometimes

71 tic fatal demyelinating disease, because its rapidly progressive demyelination in the nervous system

72 nephritis (GN) is a devastating disease with rapidly progressive deterioration in kidney function, wh

73 ial electrodiagnostic testing demonstrated a rapidly progressive diffuse sensory motor axonopathy, an

74 The cardiac defect results in a severe and rapidly progressive dilated cardiomyopathy.

75 Patients with CML in accelerated phase have rapidly progressive disease and are characteristically u

76 ic T lymphocytes (CTL) in an individual with rapidly progressive disease and high levels of viremia.

77 isease with no need for immediate therapy to rapidly progressive disease associated with therapeutic

78 By contrast, rapidly progressive disease correlated with persistent a

79 tients with multiple sclerosis who display a rapidly progressive disease course and in whom potent ph

80 ommon c.745G>A mutation generally had a less rapidly progressive disease course than the 17 cases wit

81 of these enzymes were strikingly reduced in rapidly progressive disease in homozygous cystic mice an

82 ciency virus (SIV)-infected macaques develop rapidly progressive disease in the apparent absence of d

83 54, B*55, and B*56--has been associated with rapidly progressive disease in white patients with human

84 ity of some M. tuberculosis strains to cause rapidly progressive disease may relate to their intrinsi

85 apse, and all patients in this group died of rapidly progressive disease postrelapse.

86 nti-CTLA4 monoclonal antibody developed more rapidly progressive disease than sham-treated mice, wher

87 r, nearly one third of patients experience a rapidly progressive disease with a dismal outcome.

88 ent and incomplete response with evidence of rapidly progressive disease within 2.5 months posttransp

89 enotypic spectrum from infancy (early onset, rapidly progressive disease) to childhood/adolescence an

90 /null mice are normal, Pkd1RC/null mice have rapidly progressive disease, and Pkd1RC/RC animals devel

91 PC1 and PC2 in the kidney exhibited severe, rapidly progressive disease, illustrating the importance

92 nteresting feature of plague is that it is a rapidly progressive disease, suggesting that Y. pestis e

93 ected, static CTL response in a patient with rapidly progressive disease.

94 of the identical mutation causes severe and rapidly progressive disease.

95 melanoma, a subset of patients will develop rapidly progressive disease.

96 A rapidly progressive disorder termed consumptive coagulop

97 ung development, with a phenotype comprising rapidly progressive distal airspace dilation, impaired g

98 y young age at onset, early weight loss, and rapidly progressive dopa-responsive parkinsonism, follow

99 7-year-old Italian boy with childhood-onset rapidly progressive encephalomyopathy and stroke-like ep

100 isability in the mother of a girl with RS to rapidly progressive encephalopathy in her brother.

101 Acute necrotizing encephalopathy (ANE) is a rapidly progressive encephalopathy that can occur in oth

102 High-risk neuroblastomas are rapidly progressive; even with intensive myeloablative c

103 BV-positive B lymphocytes and often follow a rapidly progressive fatal clinical course.

104 ant differential regulation in patients with rapidly progressive fibrosis.

105 e of the highest-expressing line developed a rapidly progressive fibrotic dilated cardiomyopathy and

106 body titers did not differ between cats with rapidly progressive FIV disease and long-term survivors.

107 irus load is 1 to 2 logs higher in cats with rapidly progressive FIV disease than in long-term surviv

108 al Alzheimer's disease clinical subtypes-the rapidly progressive form (r-AD) and the posterior cortic

109 ing the pathogenetic mechanisms of this most rapidly progressive form of focal segmental sclerosis is

110 rovirulent virus called FrCasE that causes a rapidly progressive form of this disease.

111 Fibrosing cholestatic hepatitis (FCH) is a rapidly progressive form of viral hepatitis B that occur

112 se requiring only brief hospitalization to a rapidly progressive, fulminant illness resulting in the

113 In this model of rapidly progressive gastritis due to H. pylori, the O ch

114 ntil age 12 years when they began developing rapidly progressive generalized dystonia.

115 s unique periodontal presentation were pain, rapidly progressive gingival recession, and significant

116 sease were 2.33 times more likely to develop rapidly progressive glaucoma disease despite significant

117 merular basement membrane (GBM) disease is a rapidly progressive glomerulonephritis (GN) resulting fr

118 lar basement membrane (GBM), usually causing rapidly progressive glomerulonephritis (GN).

119 Crescentic rapidly progressive glomerulonephritis (RPGN) represents

120 ococcal glomerulonephritis, IgA nephropathy, rapidly progressive glomerulonephritis (RPGN), and membr

121 iated vasculitis is the most common cause of rapidly progressive glomerulonephritis and immune-mediat

122 the use of PLEX to rescue organ function in rapidly progressive glomerulonephritis and lung haemorrh

123 Rapidly progressive glomerulonephritis in Goodpasture di

124 Rapidly progressing AVCD is analogous to rapidly progressive glomerulonephritis in that inner ear

125 Rapidly progressive glomerulonephritis is characterized

126 ciated vasculitis (AAV) is a common cause of rapidly progressive glomerulonephritis resulting in end-

127 e as a potential therapeutic intervention in rapidly progressive glomerulonephritis, we treated mice

128 ransplant nephritis alloantibodies mediating rapidly progressive glomerulonephritis.

129 ntigens (ANCA) is the most frequent cause of rapidly progressive glomerulonephritis.

130 utrophil accumulation in post-infectious and rapidly progressive glomerulonephritis.

131 more frequently recognized in the setting of rapidly progressive glomerulonephritis.

132 as a potential novel therapeutic strategy in rapidly progressive glomerulonephritis.

133 e focal segmental glomerulosclerosis (FSGS), rapidly progressive glomerulonephritis/idiopathic cresce

134 the formation of both cellular crescents in rapidly progressive GN and sclerotic lesions in FSGS.

135 otoxic serum to induce crescentic nephritis (rapidly progressive GN), this genetic inactivation of th

136 In a model of rapidly progressive GN, Notch3 expression was induced by

137 n in allografts as it can be associated with rapidly progressive graft failure.

138 HL) is characterized typically by bilateral, rapidly progressive hearing loss that responds therapeut

139 virus (EBOV) and Marburg virus (MARV) cause rapidly progressive hemorrhagic fever with high mortalit

140 es associating plaque angiogenesis with more rapidly progressive high-grade disease.

141 Children with rapidly progressive HIV-1 disease have more frequent EBV

142 ocrine cancers that are widely metastatic or rapidly progressive, however, the role of the medical on

143 dema appears to be decreasing, patients with rapidly progressive (hyperacute) liver failure, such as

144 lar mesenchymal cells of human subjects with rapidly progressive idiopathic pulmonary fibrosis (IPF).

145 Idiopathic pulmonary fibrosis is a rapidly progressive illness of unknown cause characteriz

146 Melioidosis pneumonia is often a rapidly progressive illness with high mortality, particu

147 All six rapidly progressive imatinib-resistant implants from fiv

148 luating the molecular etiology for isolated, rapidly progressive infantile hepatic failure.

149 specific immune responses over the course of rapidly progressive infection are not well defined.

150 nd that this inhibition did not abrogate the rapidly progressive infection in these RMs.

151 acid (AAI) nephropathy (AAN) is a common and rapidly progressive interstitial nephropathy caused by i

152 RGMc) cause juvenile hemochromatosis (JH), a rapidly progressive iron overload disorder in which expr

153 However, in mouse infections, after a delay rapidly progressive lesions appeared, and purified amast

154 tosomal dominant inheritance of a late onset rapidly progressive leukodystrophy in which exome sequen

155 he clinical details of three patients with a rapidly progressive, levodopa-unresponsive bradykinetic-

156 Necrotizing fasciitis (NF) is a rapidly progressive, life-threatening soft-tissue infect

157 hepatitis C appears to cause more severe and rapidly progressive liver disease leading more frequentl

158 mia survivors with chronic HCV may have more rapidly progressive liver disease than has been previous

159 Four patients developed rapidly progressive liver failure while receiving interf

160 nuary 1995, 13 infants were transplanted for rapidly progressive liver failure.

161 with the onset of RD at 3 weeks of age and a rapidly progressive loss of photoreceptors.

162 er the next 3 months, serial audiograms show rapidly progressive loss of threshold and word recogniti

163 t-3-deleted mice to 95% oxygen caused a more rapidly progressive lung injury associated with alveolar

164 a Minnesota resident, aged 7 years, died of rapidly progressive meningoencephalitis after local fres

165 Ethylmalonic encephalopathy is a fatal, rapidly progressive mitochondrial disorder caused by ETH

166 Group 1: Three patients developed a rapidly progressive MND, less prominent symptoms of invo

167 ion of ILK in Pkd1(fl/fl) ;Pkhd1-Cre mice, a rapidly progressive model of ADPKD, decreased renal Akt/

168 mpairment and behavioral changes followed by rapidly progressive motor and gait impairment.

169 hQ200 mice is paralleled by earlier and more rapidly progressive motor deficits: progressive imbalanc

170 al care unit for evaluation and treatment of rapidly progressive motor weakness and encephalopathy.

171 ly Hdh(neoQ20)/Hdh(neoQ111) mice exhibited a rapidly progressive movement disorder that, in the absen

172 The approach to the diagnosis of a rapidly progressive multifocal brain disorder is discuss

173 Acute liver failure can be associated with rapidly progressive multiorgan failure and devastating c

174 otentially lethal disease that presents with rapidly progressive multiple organ thromboses.

175 There were 21 patients with rapidly progressive multiple sclerosis (MS) treated on a

176 ine spinal muscular atrophy (HCSMA) features rapidly progressive muscle weakness that affects muscles

177 and lower motor neuron dysfunction and loss, rapidly progressive muscle weakness, wasting and death.

178 a new recessive mouse mutation that causes a rapidly progressive muscular dystrophy and a neonatal fo

179 A case of fatal ehrlichiosis with rapidly progressive myocarditis and multiorgan failure f

180 A 69-yr-old retired fisherman with rapidly progressive necrotizing fasciitis from Photobact

181 Deletion of CSPalpha produces rapidly progressive neurodegeneration in mice, presumabl

182 port defects have also been observed in more rapidly progressive neurodegeneration, such as that obse

183 y form of X-linked adrenoleukodystrophy is a rapidly progressive neurodegenerative disease, as devast

184 c lateral sclerosis (ALS) is one of the most rapidly progressive neurodegenerative diseases of unknow

185 ion diseases are universally fatal and often rapidly progressive neurodegenerative diseases.

186 Amyotrophic lateral sclerosis (ALS) is a rapidly progressive neurodegenerative disorder due to se

187 zheimer's disease and Parkinson disease, are rapidly progressive neurodegenerative disorders caused b

188 n levels induce SMA pathology by instigating rapidly progressive neurodegenerative pathways in lower

189 l (COFS) syndrome is a recessively inherited rapidly progressive neurologic disorder leading to brain

190 An acute and rapidly progressive neurologic syndrome developed in thr

191 ro-oculo-facio-skeletal (COFS) syndrome is a rapidly progressive neurological disorder leading to bra

192 SF RT-QuIC testing in 2,141 patients who had rapidly progressive neurological disorders, determined d

193 The latter develop rapidly progressive neurological signs around 20 days an

194 retrograde signaling pathways correlate with rapidly progressive neuronal cell death.

195 imeric murine oncornavirus FrCas(E) causes a rapidly progressive noninflammatory spongiform encephalo

196 To explore an anatomic basis for rapidly progressive OA, this observational study compare

197 We describe 2 Greek siblings who developed a rapidly progressive oculopharyngeal somatic syndrome, at

198 Infection by Ebola virus causes rapidly progressive, often fatal, symptoms of fever, hem

199 istration of the same antibodies in the more rapidly progressive P301S tauopathy model not only reduc

200 31-year-old Caucasian female presented with rapidly progressive painful proptosis of the right eye a

201 Highly aggressive Burkitt lymphoma (BL) with rapidly progressive painful proptosis of the right eye i

202 nerative disease characterized clinically by rapidly progressive paralysis leading ultimately to deat

203 nical course of CMT4J, including asymmetric, rapidly progressive paralysis, in two siblings.

204 imeric murine oncornavirus FrCas(E) causes a rapidly progressive paralytic disease associated with sp

205 Rapidly progressive PDAC was observed in the setting of

206 This report describes a case of rapidly progressive periodontal tissue breakdown and bon

207 rly-onset periodontitis (G-EOP, encompassing rapidly progressive periodontitis and generalized juveni

208 by hyperkeratosis of the palms and soles and rapidly progressive periodontitis resulting in loss of d

209 s sarcoidosis of the jaw bones that mimicked rapidly progressive periodontitis.

210 nderstanding of the etiology of juvenile and rapidly progressive periodontitis.

211 Within 31 months, six imatinib-resistant rapidly progressive peritoneal implants (metastatic foci

212 ely progressive PKD), kidneys from cpk mice (rapidly progressive PKD), and human autosomal dominant P

213 Our findings suggest that rapidly progressive pneumoconiosis in these miners was a

214 Recent recognition of rapidly progressive pneumoconiosis in younger miners, ma

215 fication scheme to determine if criteria for rapidly progressive pneumoconiosis were confirmed.

216 deficiency (MoCD) is characterised by early, rapidly progressive postnatal encephalopathy and intract

217 A severe, rapidly progressive, predominantly length dependent axon

218 promotes both reactivation TB from LTBI and rapidly progressive primary TB following recent exposure

219 ) with associated necrotizing fasciitis is a rapidly progressive process that kills 30-60% of patient

220 Four patients required reoperation for rapidly progressive pulmonary homograft stenosis; in all

221 o Jan 31, 2009, in patients with metastatic, rapidly progressive, radioiodine-refractory differentiat

222 that develop a severe glomerulosclerosis and rapidly progressive renal disease overexpress IL-4 in vi

223 en 20 years since the first description of a rapidly progressive renal disease that is associated wit

224 nction test results were normal, but she had rapidly progressive renal failure.

225 SP-B gene (121ins2) and is characterized by rapidly progressive respiratory failure immediately afte

226 aques and end-stage pulmonary fibrosis, with rapidly progressive respiratory failure.

227 Of these patients, 15 had a severe rapidly progressive sensorimotor PN (9 were wheelchair d

228 ymphomatous ONI is rare and characterized by rapidly progressive severe visual impairment.

229 cocci (CoNS) that is responsible for severe, rapidly progressive skin and soft tissue infections and

230 riant of Friend MuLV (F-MuLV) which causes a rapidly progressive spongiform neurodegenerative disease

231 unction measurements showed USH3A to be more rapidly progressive than USH2A.

232 diabetic guinea pigs resulted in severe and rapidly progressive tuberculosis (TB) with a shortened s

233 olochic acid nephropathy is characterized by rapidly progressive tubulointerstitial nephritis culmina

234 y healthy child who developed acute, severe, rapidly progressive vanishing bile duct syndrome shortly

235 Rapidly progressive vasculopathy by IVUS, defined as an

236 l follow-up of 5.9 years, more patients with rapidly progressive vasculopathy died, as compared with

237 Rapidly progressive vasculopathy was defined as the chan

238 2 (2.1%) of 76 patients without (p = 0.003) rapidly progressive vasculopathy.

239 t report of organ donation in a patient with rapidly progressive ventilator-dependent ALS.

240 N) is a disorder characterized by severe and rapidly progressive visual loss when caused by a mutatio

241 ozygous Tk2 mutant (Tk2(-/-)) mice developed rapidly progressive weakness after age 10 days and died

242 disorder characterized by motor neuron loss, rapidly progressive weakness and early death has been co

243 onsistent with humoral rejection, and showed rapidly progressive xenograft failure.