ライフサイエンスコーパス: rate constant

1 as measured by the single-turnover cleavage rate constant.

2 unctional assay to determine the dissolution rate constant.

3 sate it by keeping the actual mRNA synthesis rate constant.

4 the same driving force occurred with similar rate constants.

5 es on association (ka) and dissociation (kd) rate constants.

6 ntary reaction mechanisms and their reaction-rate constants.

7 which was hence chosen for determination of rate constants.

8 ectly correlated with the measured change in rate constants.

9 the determination of the respective kinetic rate constants.

10 d binding is obtained from solute effects on rate constants.

11 eptor subunits with different affinities and rate constants.

12 sferred to H37 bidirectionally with distinct rate constants.

13 on (up to 385%) of aerobic biotransformation rate constants.

14 ese antioxidants according to their reaction rate constants.

15 quantify changes in such vascular transport rate constants.

16 y kinetic functions to extract corresponding rate constants.

17 a and diethylurea effects on equilibrium and rate constants.

18 ted based on similarity reactions with known rate constants.

19 ases in pKa do not correlate to increases in rate constants.

20 substrates react with essentially identical rate constants.

21 cid or base catalyzed, resulting in numerous rate constants.

22 CPET process make equal contributions to the rate constants.

23 determination of the individual microscopic rate constants.

24 log orders higher paclitaxel bulk absorption rate-constants.

25 s for methanol oxidation with a second-order rate constant 2 orders of magnitude higher than that on

26 Methylation of 19 cytosines increased the rate constant 3-fold for adduction on G at the major rea

27 g concentration can alter vascular transport rate constants along with having direct tumoricidal effe

28 The systolic and diastolic rate constants also increased, while the diastolic time

29 Increased uptake rate constants, an increase in the total internal concen

30 ine a polarization for the electron-transfer rate constant and show that it correlates with the stren

31 enzyme conformational changes and chemistry (rate constants and activation enthalpy).

32 sis enables determination of the interaction rate constants and affinity of two ligands while simulta

33 ts the discrepancy among literature-reported rate constants and aids in the determination of the rate

34 es have long-established prominence, binding rate constants and binding mechanisms have gained increa

35 Whole tumor and regional rate constants and blood volume fraction (VB) were compu

36 tween the natural logarithm of the reduction rate constants and DeltarG.

37 biased estimation of key observables such as rate constants and equilibrium state populations to grea

38 ion of physical factors that control binding rate constants and mechanisms.

39 The single-turnover catalytic rate constants and Michaelis constants of the incorporat

40 hat specificity is determined by association rate constants and that variants lacking the minimal seq

41 When the ET rate constants and the maximum VOC are plotted versus th

42 and C4a-hydroxy-FAD) in the reaction, define rate constants and the order of substrate binding, and d

43 tween the log k (where k is the second-order rate constant) and the DeltaH of reaction.

44 er source had the same effect on the MS-CPET rate constants, and a combined Bronsted plot of ln(kMS-C

45 longer exponential, cannot be quantified by rate constants, and may depend on the excitation wavelen

46 (SS-QRRK) for predicting pressure-dependent rate constants, and VTST in the solid phase, liquid phas

47 The frequency distribution of rate constants appears to be log-normal, with a surprisi

48 nzene isomer showed a higher proton transfer rate constant ( approximately 25 M(-1) s(-1)) compared t

49 ations, and the simulated energy barrier and rate constants are consistent with experimental findings

50 Association rate constants are quantified in experiments as well as

51 over, it was determined that charge transfer rate constants are reliable for the establishment of adv

52 The HAT rate constants are significantly higher than those obser

53 A rate constant as high as 18 m(-1) s(-1) was obtained bet

54 he loop (segment 14-33) occurs with the same rate constant as the nucleation of helix HII (segment 33

55 e constant or the average change in multiple rate constants as compared to some reference condition.

56 high reactivity with biological thiols (with rate constants as high as 10(9) M(-1) s(-1)).

57 aic efficiency and obtain an estimate of the rate constant associated with the ORR.

58 The zero-order rate constant at 37 degrees C was the same for manuka ho

59 were fit globally to derive a single set of rate constants at 37 degrees C and a set of activation e

60 the large AQY variability, daily photolysis rate constants at the sea surface spanned a smaller rang

61 estimated were Cmax, Tmax, t1/2, elimination rate constant, AUC0-t and AUC0-inf.

62 del for accurately determining hybridization rate constants based on sequence information.

63 Indeed, the rate constants between Ohr and several fatty acid hydrop

64 amatically increases bidirectional transport rate constants, but decreases in cholesterol levels have

65 resulting in an increase in the association rate constants by up to 2 orders of magnitude.

66 (kISC), and T1 --> S0 relaxation (kT1-->S0) rate constants can be finely tuned in M-(PM')n-M compoun

67 be extracted, parameters derived from these rate constants can be recovered and used to assign mecha

68 alized that binding mechanisms, like binding rate constants, can and should be quantitatively determi

69 We show that even when exact rate constants cannot be extracted, parameters derived f

70 the changes in the nucleation and elongation rate constants caused by candidate small molecules.

71 ns exhibited similar kinetics, the unfolding rate constant changed upon deletion of the disulfide bon

72 We evidence that the heterogeneous rate constant characterizing the electron transfer betwe

73 metabolic rates (Ki, the irreversible uptake rate constant) comparable to compartment modeling.

74 ect while HEPES resulted in a 40 times lower rate constant compared to experiments in which no buffer

75 Using the rate constants compiled from literature for contaminants

76 rature-dependence of the respective reaction rate constants complied with the Arrhenius equation.

77 e physical arguments, predicts heterogeneous rate constants consistent with previous experimental obs

78 The second-order rate constants correlate linearly with the parameters E

79 Based on the measured rate constants, Cuox NPs are expected to dissolve comple

80 aerobic conditions the first-order oxidation rate constants decreased by one to several orders of mag

81 Calculation of the kinetic rate constants determining each step in the permeation e

82 ound the acidic proton is shown to influence rate constants dramatically.

83 The electron transfer (ET) rate constants driving the VOC generation are shown to v

84 c parameters (IP, induction period, min; ki, rate constant during IP, meq/kgmin) of control sample (3

85 presence of AE3 increases the acidification rate constant during pHi recovery from intracellular alk

86 files alter important atmospheric photolysis rate constants [e.g., J(NO2) and J(O3)] by attenuating s

87 nt pair with evenly matched self-propagation rate constants favors randomly distributed side chains.

88 analyses showed that the intrinsic reduction rate constants followed the order of V10 > VO2(+) > V4 >

89 The rate constant for Abeta degradation by CatB and the equi

90 werstroke, despite a twofold increase in the rate constant for actin-activated phosphate release, the

91 However, the rate constant for ATP hydrolysis (k+H + k-H) was reduced

92 The second-order rate constant for carboxylated SWCNTs reacting with (*)O

93 However, the second-order rate constant for CysK:CdiA-CT binding is two orders of

94 alyses indicate that manganese increases the rate constant for deoxynucleoside 5'-triphosphate insert

95 From competition experiments, the rate constant for H atom abstraction was determined and

96 also inactivated CBP21, but the second-order rate constant for inactivation was about 3 orders of mag

97 ic isotope effect studies determine that the rate constant for methanol oxidation on alpha-Fe2O3 is r

98 t was possible to determine the second-order rate constant for O-attack as well as for C-attack and t

99 he bilinear nature of the Eyring plot of the rate constant for pyridine ligand edge exchange reaction

100 The bimolecular rate constant for reaction of alanine with OPA is found

101 The rate constant for retinol removal increased linearly wit

102 iency arises from a higher template-mediated rate constant for the cycloaddition and lower stability

103 ation energy and a smaller electron transfer rate constant for the doubly versus singly oxidized cuba

104 The rate constant for the formation of -NH2D(+) from -NH3(+)

105 from -NH3(+) is 3660 +/- 290 s(-1), and the rate constant for the formation of -NHD2(+) from -NH2D(+

106 ted with nucleobase desolvation, whereas the rate constant for the polymerization step is influenced

107 However, the rate constant for the polymerization step is regulated b

108 The second-order rate constant for the reaction of [(PyPz)Fe(III)(OH) (OH

109 Gaussian distributed populations and Eyrings rate constant for the transition state, to describe inac

110 icin leakage can be described by first order rate constant for transport across the lipid bilayer wit

111 A comparison of the rate constant for various aromatic rings indicates that

112 Rate constants for 37 trihalomethanes, haloacetonitriles

113 In a detailed investigation, we report rate constants for all reactions in the chlorination of

114 Zero-order rate constants for artificial honey with added amino aci

115 entration was most strongly dependent on the rate constants for beta-oxidation and oxidative phosphor

116 that OS binding brings about an increase in rate constants for both the ingress and egress of substr

117 one of their key fundamental properties, the rate constants for ET between the constituent heme group

118 re identified in terms of pseudo-first-order rate constants for formation of reactive species and sec

119 thus provide predictions of the second-order rate constants for general-base-catalyzed racemization t

120 lobal kinetic modeling helped assign sets of rate constants for individual or groups of reactions, in

121 Data reveal pseudo-second-order rate constants for most MPs ranging between 1.5 and 40 g

122 We also calculated photolysis rate constants for nitrogen dioxide (NO2) and nitrate ra

123 Rate constants for non-CpG codons 244 and 243 were not i

124 c group transfer for the binding and release rate constants for nucleotides in F1-ATPase as a functio

125 We show that rate constants for racemization (measured by ourselves a

126 t the chemical scope of compounds with known rate constants for racemization in aqueous conditions wa

127 We estimated the rate constants for radiotracer transfer across the BRB (

128 rmation of reactive species and second-order rate constants for reaction of reactive species with DOM

129 e higher than previously reported (apparent) rate constants for reactions containing O2 but no added

130 Rate constants for spontaneous hydrolysis of aryl glycos

131 Rate constants for temporal decline of PCB congeners in

132 events in the experiments and obtaining the rate constants for the hydrolysis and synthesis reaction

133 Rate constants for the hydrolysis were obtained under ps

134 is approach allows determination of apparent rate constants for the oxidation of proteins by haem pro

135 ers were determined for 9 CBDs: second-order rate constants for the reactions of CBDs with ozone (kO3

136 ptivity and fluence-based pseudo-first-order rate constants for transformation of the six fluoroquino

137 he (very fast) electron transfer rates (both rate constants >/= 4000 s(-1)) and quantify the energeti

138 Degradation rate constants, half-lives and degradation percentages w

139 easured the creatine kinase forward reaction rate constant in BD.

140 eduction in creatine kinase forward reaction rate constant in the BD group (F = 4.692, p = .036), whe

141 d the alcohol, as well as a higher intrinsic rate constant in the constrained environments compared w

142 Since this reaction proceeds with a rate constant in the order of 10(-4) s(-1) despite an ex

143 by the 10(4)-10(7)-fold decrease in the HAT rate constants in acetonitrile following addition of 0.1

144 ted that the estimation of biotransformation rate constants in biofilm can be significantly biased if

145 er from chloride to the Ru metal center with rate constants in excess of 10(10) M(-1) s(-1).

146 be a useful tool for predicting inactivation rate constants in natural waters of any depth and absorb

147 results allowed estimating biotransformation rate constants in sewer biofilms, which were compared to

148 Such determination of rate constants in the total catalysis regime is a prereq

149 st order hydrogenase inactivation, providing rate constants insensitive to initial hydrogenase concen

150 The higher rate constant is caused by a greater entropy of activati

151 f the catalytic rate constant to the leakage rate constant is more than 2 orders of magnitude greater

152 lationship between acid pKa and second-order rate constants is observed for weaker acids.

153 ly on chamber walls) with methylamine with a rate constant k = (9 +/- 2) x 10(-17) cm(3) molecule(-1)

154 The rate constant k for the conversion of 3a into 3b was det

155 ed during phase 1 after rapid [Pi]-increase (rate constant k+Pi(1)) and during the single-exponential

156 nd during the single-exponential force rise (rate constant k-Pi) after rapid [Pi]-decrease.

157 ignificantly more reactive with second order rate constants k'2 that are 2-3 orders of magnitude high

158 xtures afforded an increase in the catalytic rate constant (k(obs)) of the EECC pathway, but k(obs) f

159 Calculation of the rate constant (k) and activation energy (Ea) for this hy

160 , resulting on a decrease of the degradation rate constant (k) and in several alterations in the cy3g

161 of heterogeneous standard electron-transfer rate constants (k degrees ) in a clean environment witho

162 s followed first-order kinetics and reaction rate constants (k values), which were obtained by non-li

163 5 x 10(9) M(-1) s(-1)), photon fluence-based rate constants (k') (210-2730 m(2) einstein(-1)), and qu

164 ctly different heterogeneous charge transfer rate constants (k(0) values) apply at the individual GC

165 -order reaction kinetics and the degradation rate constants (k) were calculated.

166 (*) + Br(-) --> Br2(*-), with a second-order rate constant, k = (5.4 +/- 1) x 10(8) M(-1) s(-1).

167 e formal potential (E(0)') and heterogeneous rate constant (k0) for CO2 reduction were determined wit

168 icated by the variable values of the kinetic rate constant K1 Except for 3 cases, some degree of hypo

169 ne follows a second-order reaction, with the rate constant k1 is 5.0 x 10(4) M(-1) s(-1) at pH approx

170 ring ABCB1 inhibition, retinal VT and influx rate constant K1 were significantly, by 1.4 +/- 0.5-fold

171 compartmental model to estimate the kinetic rate constants K1, K1/k2, and k3-surrogates for perfusio

172 tes autodecomposed slowly with a first order rate constant k2 = 0.003 min(-1); when a reductant was a

173 Retinal efflux rate constant k2 was significantly decreased by 2.8 +/-

174 The second-order rate constants k2 for the reactions of the iodonium ylid

175 Second-order rate constants (k2) of the reactions of various barbitur

176 ith free chlorine, exhibiting a second-order rate constant k3 = 16.8 M(-1) s(-1).

177 Apparent binding rate constants (kapp) of wild-type and mutated SR5 speci

178 Selectivity data (relative rate constants kappaobs) were collected from competition

179 ysis rate constant (kd) and its re-formation rate constant (kc).

180 kinetic parameters, the C-ON bond homolysis rate constant (kd) and its re-formation rate constant (k

181 19 and 8610 L.kg(-1).d(-1), while depuration rate constants (kd) ranged between 0.14 and 5.14 d(-1) i

182 isomerization time, the forward and backward rate constants (kE-->Z and kZ-->E) were determined.

183 electron transfer that resulted in a smaller rate constant, ket = (1.5 +/- 0.2) x 10(7) s(-1), in the

184 re-reported experimentally measured reaction rate constants, kexp, for 22 chlorine-derived inorganic

185 ing (BPND) for [(11)C]carfentanil and influx rate constant (Ki) values for [(18)F]fluorodopa were ana

186 We show that inhibition rate constants (kinh) are accurately determined for a ra

187 y PPCPs, the estimated whole-body metabolism rate constant (km) values were comparable to the observe

188 The reaction rate constants (km) for the dissolution of uranyl-vanada

189 Observed pseudo-first-order rate constants (kobs) ranged from 3.8 x 10(-3) to 7.8 x

190 ly 10(4)-10(5) M(-1) s(-1), and dissociation rate constants (koff) approximately 10(-4)-10(-3) s(-1);

191 Association rate constant kon was linearly correlated to affinity.

192 cYY binding resulted in a lower second-order rate constant (kon (CN)) but a much more stable cyanide

193 II) were surprisingly slow, with association rate constants (kon) approximately 10(4)-10(5) M(-1) s(-

194 ntibody-antigen association and dissociation rate constants, kon and koff, in a single experiment, we

195 Rate constants kp and 2kt, (M(-1)s(-1)) at 30 degrees C

196 noma tumors, to estimate uptake (K), release rate constant (kR), and hence AC, a kinetic model analys

197 The apparent heterogeneous electron transfer rate constants (kS) of CtCDH were calculated to be 21.5+

198 Also, the electron transfer rate constants (ks) of MB were estimated.

199 Uptake rate constants (ku) ranged between 0.19 and 8610 L.kg(-1

200 scence parameters, like intensity, radiative rate constant, lifetime, polarization, zero-field splitt

201 Substitution of the 57 measured second-order rate constants (log k) and the previously reported nucle

202 Binding and unbinding rate constants measured across a wide range of forces (1

203 This approach was used to re-evaluate the ET rate constants measured for several electroactive specie

204 Arrhenius plot of the adsorption/desorption rate constants measured from 9 to 55 degrees C shows tha

205 PCR rate constants were 2-7x larger than the rate constants measured with transformation assays.

206 The second-order rate constants, measured using stopped-flow kinetic tech

207 d by the development of a pseudo first-order rate constant model, and tested in a paper-based assay f

208 hat the mtSSB tetramer binds to ssDNA with a rate constant near the diffusion limit (2 x 10(9) m(-1)

209 carbonate radicals) by correlating relative rate constants (normalized to 4-chloroaniline) to EHOMO

210 ical calculations that suggest a net forward rate constant of 0.3-0.9 s(-1).

211 nifedipine/PVP, had the highest dissolution rate constant of 0.37 +/- 0.05 min(-1), and the lowest t

212 issolution can be described by a first order rate constant of 1.0x10(-9)cms(-1) at 37 degrees C.

213 age normoxic water column Hg(II) methylation rate constant of 2 x 10(-4) d(-1).

214 ted (maximum found for raffinose degradation rate constant of 3.22x10(-4)s(-1)) whereas diffusion pre

215 he temperatures that give the same effective rate constant of 3x10(-5) s(-1) , tunneling accounts for

216 complex of 1.3 10(4)mol/L and a first-order rate constant of 6.6 10(-1)s(-1) for dissociation of the

217 uM concentrations, in neutral buffer, with a rate constant of 9 M(-1) s(-1) as measured by NMR spectr

218 iction algorithm, in which the hybridization rate constant of an unknown sequence is predicted based

219 xpansion reaction takes place at 10 K with a rate constant of approximately 7.4 x 10(-7) s(-1), despi

220 uction kinetics: for both clay minerals, the rate constant of Cr(VI) reduction varies by more than 3

221 kdown also caused a 1.4-fold increase in the rate constant of Glut4 endocytosis (ken).

222 e was due primarily to a 62% decrease in the rate constant of Glut4 exocytosis (kex), although Rab10

223 O157:H7 died within 2 h with a disinfection rate constant of k = 0.01 min(-1), which is three times

224 to ground state products with a first-order rate constant of k = 2 x 10(3) s(-1).

225 lues of k+Pi(1) and k-Pi were similar to the rate constant of mechanically induced force redevelopmen

226 an intramolecular H-shift with a net forward rate constant of order 0.1 s(-1) or higher.

227 Propagation speed and rate constant of phase 2 (k+Pi(2)) had a similar [Pi]-de

228 The OER rate constant of the "fast" site was 1.70 s(-1) per atom

229 The kinetic association rate constant of the binding of the S339D/S340D mutant t

230 First, by determining the rate constant of the oxidation of PDI's redox-active Cys

231 ransfer of the Fc(2+/+) couple with standard rate constants of >/=12 cm/s as estimated from symmetric

232 ence standard and to compare pharmacokinetic rate constants of (18)F-FDG metabolism, including region

233 The rate constants of adsorption and desorption processes of

234 traviolet absorbance (SUVA), while Cu uptake rate constants of both dissolved Cu and CuO NP decreased

235 First order decay rate constants of both enterococci and E. coli were betw

236 Rate constants of carotenoid micellar incorporation were

237 Furthermore, the SL dependency of rate constants of cross-bridge distortion dynamics (c) a

238 First-order dissolution rate constants of CuO NPs increased with increasing NOM

239 erimentally determined folding and unfolding rate constants of DraE-sc and a disulfide bond-lacking D

240 inactive conformation, and have measured the rate constants of interconversion.

241 e WNV model, which can predict hybridization rate constants of new sequences to within a factor of 3

242 hrough competition experiments, the relative rate constants of O((3)P) with thiols and other function

243 from chemical reduction (66 vs 6 h(-1)) and rate constants of overall homogeneous catalysis (kobs) d

244 gths do not significantly alter the observed rate constants of PRORP2 in single-turnover cleavage ass

245 The rate constants of the above reactions were determined by

246 tic development in two ways: by altering the rate constants of the adaptive processes or by altering

247 he association (kon) and dissociation (koff) rate constants of the capture and detection antibodies a

248 of nitrite with heme iron, and the observed rate constants of the reactions were determined.

249 Conversely, the dissociation rate constants of the ternary complexes varied dramatica

250 The second-order rate constants of these reactions were 4.9 x 10(5) and 2

251 a log-linear decline in the bulk absorption rate-constant of (14)C-labeled, declining 5.5-fold per c

252 etic constants (for instance, on- versus off-rate constants) on TCR-ligand interaction and subsequent

253 ethod to determine the change in an observed rate constant or the average change in multiple rate con

254 e modifications tuned the homopolymerization rate constants over 2 orders of magnitude (0.36 M(-1) s(

255 ction coefficients, quantum yields and (*)OH rate constants predicted experimental DBP loss in a lab-

256 imple rate equations; computation of binding rate constants; quantitative determination of binding me

257 meters, such as ion channel conductances and rate constants, remains a challenging problem.

258 , we set out to determine whether changes in rate constants resulting from intravascular drug release

259 n data to a complex model including explicit rate constants results in an ill-posed problem with a va

260 y shown to be a superoxide scavenger, with a rate constant similar to superoxide dismutase.

261 upon depletion of the peroxo oxidant with a rate constant that is substrate independent.

262 e report the set of heme-heme theoretical ET rate constants that define electron flow in the tetra-he

263 he result is a clear sequence of events with rate constants that vary with experimental conditions, w

264 e experimental binding profiles for a set of rate constants that were consistent with surface plasmon

265 The pH dependence of the rate constants, the correlation between intrinsic reacti

266 Comparing to these rate constants, the kCysteine decreased whereas, kArgini

267 We present all relevant apparent bimolecular rate constants, the spectral signatures of the redox int

268 n isolation requiring no knowledge of actual rate constants themselves.

269 ssion techniques, the ratio of the catalytic rate constant to the leakage rate constant is more than

270 using different combinations of the standard rate constant, transfer coefficient, and standard potent

271 A steep increase of the peptide aggregation rate constant upon increase of solution pH from 5.0 to 6

272 quantified creatine kinase forward reaction rate constant using (31)P magnetization transfer magneti

273 nstants and aids in the determination of the rate constant using quantum mechanical calculations.

274 ed equilibrium data also allow us to propose rate constant values for some hydrolysis and disproporti

275 largely independent of the specific reaction-rate constant values, and depend on the topology of the

276 pressure on the temperature dependencies of rate constants versus substrate KIEs provides direct evi

277 lopes of the plots of the pseudo-first-order rate constants versus the concentrations of the reactant

278 An exponential attenuation of the PCET rate constant was found: kPCET(d) = k(0)PCETexp[-beta(d

279 The degradation rate constant was improved by 29 times in the presence o

280 The temperature dependence of the rate constants was found to obey the Arrhenius law in a

281 ngth of the entire pWH1266 plasmid, the qPCR rate constants were 2-7x larger than the rate constants

282 ture, self-propagation and cross-propagation rate constants were determined according to a terminal c

283 d little (0.12-0.59 mol/Einstein), such that rate constants were driven by the orders of magnitude va

284 Calculated pseudo-first order reaction rate constants were in the following order; kCysteine>kA

285 At four sites, methylation rate constants were low in snowpacks (km = 0.001-0.004 d

286 minant treatment, test compound electrolysis rate constants were measured in authentic latrine wastew

287 the Michaelis-Menten parameters and maximal rate constants were not significantly different.

288 stopped-flow spectrofluorimetry, association rate constants were observed to approach the diffusion l

289 first-order conditions, and the second-order rate constants were obtained as the slopes of the plots

290 The cross-propagation rate constants were obtained by nonlinear least-squares

291 The apparent rate constants were similar for all the sorbents, RHs an

292 First order decay rate constants were well correlated to the daily average

293 The estimated reaction rate constants were within 1 order of magnitude for pH 7

294 orous particle, expressed as a heterogeneous rate constant, were nearly 50-times faster than the pyre

295 med from 1-deoxyglucosone with high reaction rate constants while glyoxal formed through glucose degr

296 loped solely using the second order reaction rate constant with ozone (kO3).

297 Computed rate constants with and without tunneling confirm that t

298 Bimolecular reaction rate constants with hydroxyl radicals ranged from (2.04

299 10(9) M(-1) s(-1) and showed an increase in rate constants with increasing carbon side-chain length.

300 The good agreement of extracted rate constants with literature values and analogous SPR