ライフサイエンスコーパス: rate-limiting step

1 e-independent, relatively slow, and thus the rate-limiting step).

2 n of the catalyst resting state and turnover-rate limiting step.

3 the product complex would correspond to the rate-limiting step.

4 emains linear, consistent with an unchanging rate-limiting step.

5 lified quantitative models based on a single rate-limiting step.

6 viously assumed and sorption serves as a key rate-limiting step.

7 thway confirms that CC bond formation is the rate-limiting step.

8 ies indicate that C-H palladation is not the rate-limiting step.

9 ed state, and P3 disruption occurs after the rate-limiting step.

10 We also report that NTD assembly is the rate-limiting step.

11 C-H activation would not be involved in the rate-limiting step.

12 ution rates were also measured to define the rate-limiting step.

13 ition of pyrimidine modifications might be a rate-limiting step.

14 e proton-transfer reaction coordinate in the rate-limiting step.

15 rmediate to a small-molecule acceptor is the rate-limiting step.

16 p to reach a definitive conclusion about the rate-limiting step.

17 he C-S bond in the substrate Me-S-CoM is the rate-limiting step.

18 t photo-oxidation of PhPyr by the QDs is the rate-limiting step.

19 nd demonstrate that product formation is the rate-limiting step.

20 and a simple classifier for determining the rate-limiting step.

21 ent, suggesting that ejection of the SM is a rate-limiting step.

22 tely 58 s(-1) so that PPi release became the rate-limiting step.

23 fect indicate that H-H bond formation is the rate-limiting step.

24 the requisite allosteric coupling, remains a rate-limiting step.

25 nalysis reveals the presence of at least two rate limiting steps.

26 ation but is useful in diagnosing additional rate-limiting steps.

27 P14 is formed in the rate-limiting step along the conformational selection pa

28 nformational selection pathway but after the rate-limiting step along the induced-fit pathway.

29 These experiments reveal a slow, rate-limiting step along the unfolding pathway.

30 Pt(IV) hydroperoxo species 4 is the reaction rate-limiting step and (ii) the anionic complex 2 is mor

31 d, it acts as a viable proton donor past the rate-limiting step and a sluggish buffer that maintains

32 ions show that the C-H activation is not the rate-limiting step and indicate that the reaction procee

33 Deuteration shifts the rate-limiting step and markedly alters the concentration

34 lso shows that the first priming step is the rate-limiting step and partial agonists require an incre

35 tional strategies agree on the nature of the rate-limiting step and provided close results for the re

36 t tertiary mutations may be used to identify rate-limiting steps and dissect folding and assembly pat

37 Rate studies reveal that rate-limiting steps and even the choice of reaction coor

38 in conditions routinely cause shifts in the rate-limiting steps, and autocatalysis is prevalent and

39 The calculated reaction barrier of the rate-limiting step ( approximately 22 kcal mol(-1)) is c

40 this strange region of nonlimiting behavior, rate-limiting steps are often poorly defined, sometimes

41 anscription being initiated through a single rate limiting step, as it had been previously proposed,

42 the proton transfer is occurring during the rate-limiting step, as in the distinction between genera

43 The overall rate-limiting step associated with the highest energetic

44 Reduction of Pu(V) was found to be the rate-limiting step at concentrations higher than approxi

45 Adsorption of Pu(V) was found to be the rate-limiting step at plutonium concentrations less than

46 oplet reactions and it is concluded that the rate-limiting step at steady state is reagent transport

47 minant parallel and consecutive pathways and rate limiting steps by estimating the reaction rate cons

48 gy status regulates atRA biosynthesis at the rate-limiting step, catalyzed by retinol dehydrogenases

49 a two-step transmetalation with a low energy rate-limiting step characterized by a four-center transi

50 The rate-limiting step during electrocatalysis is determined

51 strate that Jak3 autophosphorylation was the rate-limiting step during Jak3 trans-phosphorylation of

52 e show that Jak3 autophosphorylation was the rate-limiting step during Jak3 trans-phosphorylation of

53 somerization of proline peptide bonds is the rate-limiting step during triple-helix formation.

54 Activation of myofibroblast rich stroma is a rate-limiting step essential for cancer progression.

55 by CuO through outer-sphere interaction, the rate-limiting step, followed by a rapid reaction with 2,

56 he first carbon-carbon bond formation is the rate-limiting step, followed by a rotation about the new

57 suggesting that CGA hydrolysis could be the rate limiting step for CO2 formation from CGA.

58 neO intermediate (O-O bond formation) is the rate limiting step for OER catalysis at low pH.

59 the voltage sensor in the first domain is a rate limiting step for release of the inactivation domai

60 red by z-exchange spectroscopy represent the rate-limiting step for a one-base-pair shift from the sp

61 Release of ATP is a rate-limiting step for activating caspase-1, as extracel

62 We found that the overall rate-limiting step for aldol cleavage shifted from C-C b

63 nts that suggest the isomerization to be the rate-limiting step for bispropargyl ethers, while cycliz

64 ate of hydration of [Formula: see text] is a rate-limiting step for calcite dissolution in seawater.

65 es and high-energy states can constitute the rate-limiting step for catalytic turnover.

66 Identification of the rate-limiting step for cellobiohydrolases remains contro

67 s C, syntrophic propionate oxidation was the rate-limiting step for CH4 production; above this thresh

68 ound charge pairs is identified as the major rate-limiting step for charge carriers' generation.

69 f the metallacyclobutane intermediate is the rate-limiting step for cyclic olefins having ring sizes

70 The rate-limiting step for initiation of alternative NHEJ is

71 Glucokinase (GK) is the rate-limiting step for insulin release from the pancreas

72 eased the basal PDE activity and speeded the rate-limiting step for phototransduction deactivation, c

73 nclude that Na(+) binding is most likely the rate-limiting step for substrate binding.

74 y stroke (slowed 3-fold), which could be the rate-limiting step for the ATPase cycle.

75 In samples containing excess albumin the rate-limiting step for the chronopotentiometry readout a

76 del predicted that monomer activation is the rate-limiting step for the entire pore formation process

77 most likely arising from differences in the rate-limiting step for the two activities.

78 It is also unclear whether the rate-limiting step for transport occurs at the nuclear b

79 n can be accounted for by assuming different rate-limiting steps for ChiA and Cel7A.

80 flavodoxin reported a major revision of the rate-limiting step from MoFe protein and Fe protein diss

81 action, catalyst resting state, and turnover-rate limiting step has been examined.

82 These changes in dominant rate-limiting steps have a direct effect on the duty rat

83 It can also be a rate-limiting step if high false positive or negative ra

84 uptake mechanism with N-chlorination as the rate-limiting step; (ii) under alkaline conditions, N-ch

85 technologies, genetic mapping has become the rate limiting step in mammalian forward genetics.

86 us preventing the eIF4F complex formation, a rate limiting step in the translation initiation cascade

87 pecific aspects include the time scales, the rate limiting steps in the degradation pathway, the effe

88 The present work gives insight into the rate limiting steps in the reaction mechanism, the effec

89 n of CYP27A1, the enzyme responsible for the rate-limiting step in 27-hydroxycholesterol biosynthesis

90 s and provides a simple means to predict the rate-limiting step in a folding reaction.

91 hat is coupled to Lck; this is the first and rate-limiting step in a kinetic proofreading chain of ev

92 ing have made computational analysis a major rate-limiting step in adaptive laboratory evolution and

93 experiments implicate C-H activation as the rate-limiting step in all cases.

94 E-1 (beta-site APP cleaving enzyme-1) is the rate-limiting step in amyloid-beta (Abeta) production an

95 mbrane integration of the beta domain is the rate-limiting step in autotransporter assembly and that

96 cid dehydrogenase (BCKD) responsible for the rate-limiting step in BCAA catabolism.

97 on of metastasis suppressor genes is a major rate-limiting step in breast cancer progression that pre

98 artments that increase the efficiency of the rate-limiting step in carbon fixation by sequestering re

99 e 1 (3betaHSD1), which catalyzes the initial rate-limiting step in conversion of the adrenal-derived

100 Because nucleotide exchange is the rate-limiting step in cyclical activation of G-proteins,

101 (IPT; encoding the enzyme that mediates the rate-limiting step in cytokinin synthesis) under the con

102 As enzyme activity is the putative rate-limiting step in decomposition, enhanced activity d

103 ncentrations above approximately 100 nm, the rate-limiting step in detergent- or membrane- induced po

104 onstrate that the search for homology is the rate-limiting step in DSB repair and suggest that cells

105 The rate-limiting step in each mechanism is **COOH formation

106 A rate-limiting step in efficiently applying TALEN and CRI

107 vious studies, our findings suggest that the rate-limiting step in enzymatic cellulose degradation is

108 ic acid (ACC) synthases (ACS), generally the rate-limiting step in ethylene biosynthesis, which is re

109 uggesting that triglyceride hydrolysis was a rate-limiting step in EVO degradation and subsequent rea

110 se (ACC), the enzyme that controls the first rate-limiting step in fatty acid biosynthesis.

111 during early stages of folding, prior to the rate-limiting step in folding.

112 -hydroxyproline or 4-hydroxyproline, and the rate-limiting step in formation of the triple helix is t

113 called poly(A) tail shortening, is the first rate-limiting step in general cytoplasmic mRNA degradati

114 n, and that proteolysis is the regulated and rate-limiting step in generating soluble EGF bioactivity

115 A rate-limiting step in gluconeogenesis is the conversion

116 Pyruvate kinase catalyzes the last and rate-limiting step in glycolysis and theMtbgenome harbor

117 synthesis pathway catalyzing the initial and rate-limiting step in glycosaminoglycan chain assembly.

118 The rate-limiting step in green fluorescent protein is assig

119 h) acyltransferase (HHAT) that catalyzes the rate-limiting step in Hh ligand production.

120 using by RNA polymerase II (Pol II) is a key rate-limiting step in HIV-1 transcription and latency re

121 and it shows that mTEC homeostasis is not a rate-limiting step in intrathymic Foxp3(+) Treg producti

122 iption of Atgl, the enzyme that mediates the rate-limiting step in lipolysis, is a key point of this

123 ulating deadenylation, the initial and often rate-limiting step in mRNA degradation.

124 Although the expression of Fn14 is a rate-limiting step in muscle atrophy on denervation, mec

125 amide phosphoribosyltransferase (NAMPT), the rate-limiting step in NAD(+) synthesis, is highly expres

126 dent expression of NLRP3, which represents a rate-limiting step in NLRP3 inflammasome assembly.

127 ed heterolytic O-O bond cleavage of 2 as the rate-limiting step in olefin oxidation.

128 cellular carboxylesterases is considered the rate-limiting step in polyester biodegradation.

129 l cis-trans prolyl-isomerization (PPIase), a rate-limiting step in protein folding and a conformation

130 ed view of an intein poised to carry out the rate-limiting step in protein splicing, shedding light o

131 suitable conditions for crystallization is a rate-limiting step in protein structure determination.

132 that MOR conformational changes are not the rate-limiting step in receptor activation.

133 RP3) inflammasome activation often acts as a rate-limiting step in regulating critical cell-fate deci

134 Cleavage at the NS2/3 junction is a rate-limiting step in replication of particular HCV isol

135 mediated by RNA polymerase I represents the rate-limiting step in ribosome biogenesis.

136 so2-Sec9 'binary' t-SNARE complex, the early rate-limiting step in SNARE complex assembly, and stimul

137 nsferase, an enzyme catalyzing the first and rate-limiting step in sphingolipid biosynthesis: the con

138 ort to the inner mitochondrial membrane, the rate-limiting step in steroid hormone biosynthesis.

139 nzyme A reductase (HMGCR), which catalyzes a rate-limiting step in synthesis of cholesterol.

140 nit of PRC2 indicate that demethylation is a rate-limiting step in the activation of such genes.

141 We now conclude that the rate-limiting step in the base-catalyzed aldol condensat

142 butyrate dehydrogenase 2 (Bdh2), catalyzes a rate-limiting step in the biogenesis of the eukaryotic s

143 nase (SDR) family of reductases, catalyzes a rate-limiting step in the biogenesis of the mammalian si

144 However, PhCCR1 does not perform a rate-limiting step in the biosynthesis of phenylpropenes

145 ive sentinel is heme oxygenase-1 (HO-1), the rate-limiting step in the catabolism of heme into the bi

146 on of relative configuration is frequently a rate-limiting step in the characterization of small orga

147 d others demonstrated that the regulated and rate-limiting step in the choline pathway for PC biosynt

148 f goethite, suggesting Fe(II) release is the rate-limiting step in the conduction mechanism during re

149 ation of its native tetrameric assembly is a rate-limiting step in the conversion from a native struc

150 osomal proteases functioning in a direct and rate-limiting step in the Ctr1 ectodomain cleavage.

151 Axin, a scaffolding protein that controls a rate-limiting step in the destruction of beta-catenin, t

152 sible for biliary secretion of bile acids, a rate-limiting step in the enterohepatic circulation of b

153 Phospholipase A2s mediate the rate-limiting step in the formation of eicosanoids such

154 oming the immune response to senescence is a rate-limiting step in the formation of IR-induced osteos

155 ependent rate of intersystem crossing is the rate-limiting step in the formation of photo-Favorskii o

156 ch slower than either fingers closing or the rate-limiting step in the forward direction; this rate b

157 alled poly(A) tail shortening, is the first, rate-limiting step in the general cytoplasmic mRNA degra

158 substrate molecules from the bilayer is the rate-limiting step in the hydrolysis of GPLs by some sec

159 R by suppressing end resection, which is the rate-limiting step in the initiation of HDR.

160 yptophan 2,3-dioxygenase, which catalyze the rate-limiting step in the kynurenine pathway, producing

161 talization (senescence bypass) is a critical rate-limiting step in the malignant transformation of ma

162 l colonization of the secondary organ is the rate-limiting step in the metastatic process; thus, expe

163 The rate-limiting step in the NAD(+) biosynthetic pathway fr

164 ceptors coating the mRNA and that there is a rate-limiting step in the nuclear basket that is potenti

165 Heme oxygenase (HO) catalyzes the rate-limiting step in the O2-dependent degradation of he

166 and -2.8, respectively, indicating that the rate-limiting step in the oxidations involves hydride ab

167 eparating lower and upper glycolysis, is the rate-limiting step in the pathway and the levels of fruc

168 tidic acid phosphatase (PAP) controlling the rate-limiting step in the phospholipid synthesis pathway

169 The rate-limiting step in the production of Abeta from APP i

170 rucial intermediates for the selectivity and rate-limiting step in the proposed Rh(I)-catalytic cycle

171 ot observed with 1b, which suggests that the rate-limiting step in the reaction is neither C-H activa

172 for the substrate and the alteration of the rate-limiting step in the reaction.

173 also promotes HC relaxation to accelerate a rate-limiting step in the repair of complex genomes.

174 enhances product release, which also is the rate-limiting step in the steady-state.

175 Tyrosine hydroxylase (TH) catalyzes the rate-limiting step in the synthesis of catecholamine neu

176 sion of l-tyrosine into l-DOPA, which is the rate-limiting step in the synthesis of catecholamines, s

177 ables provide quantitative evidence that the rate-limiting step in the TPP(+) transport cycle is not

178 this case, a slow transient process was the rate-limiting step in the transitions.

179 t catalyses the first committed reaction and rate-limiting step in the urea cycle.

180 These observations suggest that the rate-limiting step in this reaction is protonation of th

181 Initiation is a highly regulated, rate-limiting step in transcription.

182 In unicellular organisms, initiation is the rate-limiting step in transcription; in metazoan organis

183 By mediating the rate-limiting step in triacylglycerol hydrolysis, adipos

184 Phenotyping has become the rate-limiting step in using large-scale genomic data to

185 Positive correlations suggest that the rate-limiting steps in biosynthesis of glucosinolates in

186 t mechanism of adaptation was to relieve the rate-limiting steps in cofactor metabolism and substrate

187 e microtubule (MT; KT capture) is one of the rate-limiting steps in establishing proper KT-MT interac

188 ngs help reveal the nature and origin of the rate-limiting steps in substrate translocation on the ba

189 a1, which encode enzymes responsible for the rate-limiting steps in the classic and alternate bile ac

190 xygenase 2 (COX-2), an enzyme that catalyzes rate-limiting steps in the conversion of arachidonic aci

191 ation of the rates, and determination of the rate-limiting steps in the paradigmatic case of the tryp

192 lial margination and tissue recruitment, are rate-limiting steps in the periodontal inflammatory proc

193 entify the primary HS response genes and the rate-limiting steps in the transcription cycle that GAGA

194 lained by differences in the kinetics of the rate-limiting steps in transcription between promoters a

195 and eIF4F complex assembly are the two major rate-limiting steps in translation initiation regulated

196 encing (WGS), genetic mapping has become the rate-limiting step, inhibiting unbiased forward genetics

197 The rate-limiting step involves movement of the tetracationi

198 inding and activity can be reconciled if the rate-limiting step is after the catalysis (i.e. in the d

199 The overall nitrogenase rate-limiting step is associated with ATP-driven electro

200 he diffusion through the coating and (2) the rate-limiting step is the diffusion through the aqueous

201 s can be simplified into two models: (1) the rate-limiting step is the diffusion through the coating

202 according to the theoretical discussion, the rate-limiting step is the diffusion through the coating;

203 The rate-limiting step is the iodine abstraction from an alk

204 he self-immolative reaction reveals that the rate-limiting step is the release of the first fluoride

205 , there might be intermediate steps, but the rate-limiting step is the same.

206 ng the mechanisms behind translation and its rate-limiting steps is crucial for both the development

207 cause product release occurs after a second, rate-limiting step, many cycles of intermediate formatio

208 uropsychiatric disease genetics in which the rate-limiting step may no longer be gene discovery.

209 ast two distinct reaction mechanisms or that rate-limiting steps might vary.

210 responsible for bilirubin glucuronidation, a rate-limiting step necessary for bilirubin metabolism an

211 inhibition of acetyl CoA carboxylase 1, the rate limiting step of FAS, inhibit generation of early m

212 ed in the presence of the secretome, and the rate limiting step of the reaction was the oxidation of

213 dedimerization, with energy barriers for the rate-limiting step of 29.9 kcal/mol for C-methyl nitrone

214 ting cytosines and causing U:G mismatches, a rate-limiting step of Ab gene diversification.

215 rst electron transfer to the NAC was not the rate-limiting step of abiotic reduction.

216 sium ions, and the processes that govern the rate-limiting step of ADP release are unresolved.

217 latory protein (StAR), which facilitates the rate-limiting step of aldosterone steroidogenesis.

218 SS1) to inactivate ASS1, which catalyzes the rate-limiting step of arginine biosynthesis.

219 ASS1 catalyzes the rate-limiting step of arginine synthesis in urea cycle a

220 e first electron transfer to the NAC was the rate-limiting step of bioreduction.

221 cine amidinotransferase (GATM) catalyzes the rate-limiting step of creatine biosynthesis: the transfe

222 se, the enzyme responsible for the first and rate-limiting step of de novo sphingolipid biosynthesis.

223 rotein fluctuations and product release, the rate-limiting step of DHFR catalysis.

224 Ribonucleotide reductase (RR) catalyzes the rate-limiting step of dNTP synthesis and is an establish

225 The rate-limiting step of eicosanoid generation is the liber

226 a general acid nor a reaction partner in the rate-limiting step of electrochemical CO2 reduction cata

227 EEDs address the critical rate-limiting step of endosomal escape in delivery of ma

228 However, overcoming the rate-limiting step of endosomal escape into the cytoplas

229 e 1a (CPT1a) is a protein that catalyzes the rate-limiting step of FAO, here we investigated the in v

230 sion that FOL2 was the key gene encoding the rate-limiting step of folate biosynthesis in wine yeast.

231 ctions in the viral envelope may control the rate-limiting step of fusion.

232 enzyme in glycogen metabolism, catalyzes the rate-limiting step of glycogen mobilization.

233 vealing that a single H/D is involved in the rate-limiting step of H2 formation.

234 The analysis suggests that the rate-limiting step of hydrolysis is the transport of the

235 Kinetic analysis revealed the rate-limiting step of inactivation of the PLP-dependent

236 ase, the enzyme that catalyzes the first and rate-limiting step of inositol biosynthesis.

237 creased due to a reaction at a N atom in the rate-limiting step of NDMA formation.

238 eins, the last of which acts to accelerate a rate-limiting step of nucleotide exchange of Hsc70.

239 The rate-limiting step of PAR signaling is determined by the

240 nt of viral hemagglutinin, which affects the rate-limiting step of pH-triggered fusion.

241 the activation loop which might speed-up the rate-limiting step of phosphorylation.

242 ed isoform of the CEK family involved in the rate-limiting step of PtdCho biosynthesis and appears to

243 d suggest that PCSK9 self-proteolysis is the rate-limiting step of secretion.

244 cs, indicating that glycine formation is the rate-limiting step of SHMT catalysis.

245 Arguably, the first and rate-limiting step of SNARE assembly is the formation of

246 o 0.05 s(-1), making the hydrolysis step the rate-limiting step of the ATPase cycle in the presence a

247 In addition to decreasing the rate-limiting step of the cycle (phosphate release), mav

248 The rate-limiting step of the cycle is nucleotide exchange o

249 om carboxybiotin to oxamate is the partially rate-limiting step of the enzymatic reaction.

250 release of hydrogen, and we suggest that the rate-limiting step of the HER is the reduction and proto

251 ansition state supports a model in which the rate-limiting step of the hybridization reaction is the

252 The initial and rate-limiting step of the kynurenine pathway involves ox

253 ss plays a key regulatory role in the first, rate-limiting step of the kynurenine pathway, which prod

254 kov state model that allowed identifying the rate-limiting step of the ligand unbinding process.

255 pe effects have been used to interrogate the rate-limiting step of the Michael addition of glycinate

256 The rate-limiting step of the overall mechanism is a conform

257 emonstrated that the second arylation is the rate-limiting step of the overall transformation.

258 he transition state, thereby determining the rate-limiting step of the phosphorylation reaction of ar

259 by the catalyst as well as to determine the rate-limiting step of the process, which consists in the

260 activation is associated with changes in the rate-limiting step of the reaction caused by additional

261 In the rate-limiting step of the reaction, Ag(I)-carboxylate is

262 his intermediate is attacked by HS(-) in the rate-limiting step of the reduction reaction.

263 the key metabolic enzyme that catalyzes the rate-limiting step of the serine biosynthesis pathway, i

264 isotopic labeling studies indicates that the rate-limiting step of the transformation is the encapsul

265 the other hand, for nonpolar compounds, the rate-limiting step of the uptake process is diffusion th

266 ng using stalled polyribosomes to bypass the rate-limiting step of translation initiation.

267 glycerol acyltransferases (DGATs) catalyze a rate-limiting step of triacylglycerol (TAG) biosynthesis

268 at dysregulation of cell fate may be a novel rate-limiting step of tumorigenesis.

269 ng Neu5Ac cleavage, the enzyme catalyzes the rate-limiting step of two biocatalytic reactions produci

270 l-tRNA reductase, which catalyzes one of the rate-limiting steps of chlorophyll biosynthesis.

271 f transcriptional complexes that control the rate-limiting steps of hepatic glucose release and accre

272 yclonals'-effectively bypass the potentially rate-limiting steps of membrane translocation and glycos

273 gain insight into the stereodetermining and rate-limiting steps of the reaction.

274 l protein hubs and DNA processing during the rate-limiting steps of transcription.

275 ll drug-sensitive cancer cells have a single rate-limiting step on the path to cell death.

276 that spontaneously converted CO2 to CO in a rate-limiting step on the second time scale in the dark

277 orbital (EHOMO)] to specific for the likely rate-limiting step [one-electron oxidation potentials (E

278 rone, indicating that C-H bond breaking is a rate-limiting step over a 10(4)-fold range of catalytic

279 Their phosphorylation differs by the rate-limiting steps: product release is rate-limiting fo

280 e promoter-proximal pausing of RNAPII, a key rate-limiting step required for productive elongation.

281 on an agar-filled Petri dish; however, this rate-limiting step requires up to 12 h of incubation tim

282 The rate-limiting step (RLS) in the catalytic cycle is not t

283 With increasing DO, the rate slowed and the rate-limiting step shifted from surface oxidation to U(V

284 ch dichotomous kinetics implicate additional rate-limiting steps that are essential for DNA-damage-in

285 phasizes that niclosamide degradation is the rate-limiting step to dehalogenation and mineralization

286 f.i-Bu3N bearing a hindered amine shifts the rate-limiting step to proton transfer.

287 nd use different substrates, reveal that the rate-limiting step under these conditions is the H2 form

288 determined by isocyanide addition, while the rate-limiting step was found to deviate from traditional

289 To exert control over this rate-limiting step, we designed sequence-specific synthe

290 (+)) binding result in a voltage-independent rate-limiting step where SERT may return to the outward-

291 present in both intermediate states, and the rate-limiting step which is likely to involve the thread

292 n barrier and a greater entropy gain for the rate-limiting step, which eventually leads to propene.

293 single proton is critical in the peroxidase rate-limiting step, which is very likely the proton-coup

294 hanges to 2, consistent with a change of the rate-limiting step, which now involves oxidation of comp

295 ion of the compound II to resting state is a rate-limiting step, which will explain the contradictory

296 OA is the rate-limiting step, while RE determines selectivity: the

297 wo CO2 molecules synchronously, which is the rate-limiting step with an energy barrier of 0.47 eV.

298 nding trajectories and describe the critical rate-limiting steps with unprecedented detail.

299 transfer of the second hydrogen atom, is the rate-limiting step, with a computed free energy barrier

300 ailoring elegantly precise inhibitors of the rate-limiting steps within the signaling pathways that c